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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|238922433|ref|YP_002935946.1| chromosomal replication initiation protein (EUBREC_0001) [Eubacterium rectale ATCC 33656] 453 COG1018 3-452 -118.000 33  [L] COG0593 ATPase involved in DNA replication initiation
CSGID 1-451 -125.000 45  IDP00004 Chromosomal replication initiator protein dnaA BA_0001 [Bacillus anthracis str. Ames]
H.sapiens 84-327 -11.000 15  sp|Q96S55|WRIP1_HUMAN ATPase WRNIP1 OS=Homo sapiens GN=WRNIP1 PE=1 SV=2 (Range: 151-450)
114-349 -13.400 12  sp|Q9NVI7|ATD3A_HUMAN ATPase family AAA domain-containing protein 3A OS=Homo sapiens GN=ATAD3A PE=1 SV=2 (Range: 301-600)
132-425 -12.300 11  sp|Q13608|PEX6_HUMAN Peroxisome assembly factor 2 OS=Homo sapiens GN=PEX6 PE=1 SV=2 (Range: 451-750)
149-370 -14.300 14  sp|Q6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 OS=Homo sapiens GN=ATAD2 PE=1 SV=1 (Range: 451-750)
HGM_OVER 111-444 -3.420 11  PB005684 gi|160884252|ref|ZP_02065255.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]gi|156109991|gb|EDO11736.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]
NEW_HUMAN_DOMAINS 255-408 -4.900 11  sp|Q8NFP9|NBEA_HUMAN Neurobeachin OS=Homo sapiens GN=NBEA PE=1 SV=3 (Range: 1330-1485)
PDB1018 7-453 -116.000 34  2z4r_A mol:protein length:440 Chromosomal replication initiator protein dnaA
PfamA32U 5-71 -14.200 20  PF11638.8; DNAA_LAWIP/5-67; DnaA N-terminal domain
113-334 -97.600 60  PF00308.18; DNAA_STRCO/317-535; Bacterial dnaA protein
149-442 -10.100 13  PF03969.16; ZAPE_ECOLI/4-371; AFG1-like ATPase
361-429 -35.100 42  PF08299.11; D9QS97_ACEAZ/358-426; Bacterial dnaA protein helix-turn-helix
SCOP207 111-329 -91.100 38  d1l8qa2 c.37.1.20 (A:77-289) Chromosomal replication initiation factor DnaA {Aquifex aeolicus [TaxId: 63363]}
346-453 -43.400 24  d1l8qa1 a.4.12.2 (A:290-399) Chromosomal replication initiation factor DnaA C-terminal domain IV {Aquifex aeolicus [TaxId: 63363]}
VFDB 3-452 -118.000 33  [L] COG0593 ATPase involved in DNA replication initiation
2 gi|238922434|ref|YP_002935947.1| DNA polymerase III, beta subunit (EUBREC_0002) [Eubacterium rectale ATCC 33656] 370 COG1018 1-368 -98.400 22  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
CSGID 1-365 -97.900 24  IDP90614 DNA polymerase III subunit beta [Vibrio cholerae O1 biovar eltor str. N16961] VC0013 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 136-370 -12.100 11  sp|P12004|PCNA_HUMAN Proliferating cell nuclear antigen OS=Homo sapiens GN=PCNA PE=1 SV=1
HGM_OVER 7-343 -4.700 PB004476 gi|139436894|ref|ZP_01771054.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]gi|133776541|gb|EBA40361.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]
NEW_HUMAN_DOMAINS 306-345 -4.230 17  tr|F5GXK0|F5GXK0_HUMAN Uncharacterized protein OS=Homo sapiens GN=ANK3 PE=4 SV=1 (Range: 101-205)
PDB1018 1-370 -106.000 100  3t0p_A mol:protein length:371 DNA polymerase III, beta subunit
PfamA32U 1-118 -46.800 33  PF00712.19; DPO3B_CAUVC/1-121; DNA polymerase III beta subunit, N-terminal domain
128-243 -49.500 28  PF02767.16; DPO3B_PSEPK/129-244; DNA polymerase III beta subunit, central domain
245-364 -44.900 29  PF02768.15; DPO3B_BACSU/253-376; DNA polymerase III beta subunit, C-terminal domain
SCOP207 1-121 -54.200 23  d5w7za1 d.131.1.0 (A:1-122) automated matches {Rickettsia conorii [TaxId: 272944]}
122-244 -53.300 29  d4k3la2 d.131.1.1 (A:123-244) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
245-366 -49.300 25  d1vpka3 d.131.1.1 (A:244-366) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
VFDB 1-368 -98.400 22  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
3 gi|238922435|ref|YP_002935948.1| hypothetical protein (EUBREC_0003) [Eubacterium rectale ATCC 33656] 71 COG1018 5-70 -33.800 40  [S] COG2501 Uncharacterized conserved protein
CSGID 13-71 -21.600 22  IDP91360 16S rRNA uridine-516 pseudouridylate synthase [Vibrio vulnificus CMCP6] VV1_2843 [Vibrio vulnificus CMCP6]
H.sapiens 14-63 -14.700 16  sp|P46781|RS9_HUMAN 40S ribosomal protein S9 OS=Homo sapiens GN=RPS9 PE=1 SV=3
HGM_OVER 24-57 -3.390 20  PB015266 gi|154494998|ref|ZP_02034003.1| hypothetical protein PARMER_04044 [Parabacteroides merdae ATCC 43184]gi|154085548|gb|EDN84593.1| hypothetical protein PARMER_04044 [Parabacteroides merdae ATCC 43184]
NEW_HUMAN_DOMAINS 1-68 -6.150 16  sp|Q8IUI8|CRLF3_HUMAN Cytokine receptor-like factor 3 OS=Homo sapiens GN=CRLF3 PE=1 SV=2 (Range: 281-442)
PDB1018 9-70 -37.900 35  1p9k_A mol:protein length:79 orf, hypothetical protein
PfamA32U 6-69 -37.000 57  PF13275.6; D4IXS8_BUTFI/4-68; S4 domain
SCOP207 9-70 -37.700 35  d1p9ka1 d.66.1.6 (A:3-79) Hypothetical protein YbcJ {Escherichia coli [TaxId: 562]}
VFDB 5-70 -33.800 40  [S] COG2501 Uncharacterized conserved protein
4 gi|238922436|ref|YP_002935949.1| DNA replication and repair protein RecF (EUBREC_0004) [Eubacterium rectale ATCC 33656] 362 COG1018 1-359 -103.000 23  [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
CSGID 1-359 -103.000 23  IDP00109 gene: recF; Rec protein NT01SF4517 [Shigella flexneri 2a str. 2457T]
H.sapiens 1-244 -16.900 15  sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 OS=Homo sapiens GN=RAD50 PE=1 SV=1 (Range: 1-300)
3-199 -18.700 13  sp|Q8IY18|SMC5_HUMAN Structural maintenance of chromosomes protein 5 OS=Homo sapiens GN=SMC5 PE=1 SV=2 (Range: 1-300)
120-337 -12.100 13  sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 OS=Homo sapiens GN=RAD50 PE=1 SV=1 (Range: 1051-1312)
HGM_OVER 211-362 -3.540 10  PB011051 Q8A0P0_BACTN/1-227 PB011051; Pfam-B_11051;
NEW_HUMAN_DOMAINS 258-308 -4.820 sp|Q6ZUM4|RHG27_HUMAN Rho GTPase-activating protein 27 OS=Homo sapiens GN=ARHGAP27 PE=1 SV=3 (Range: 141-208)
PDB1018 1-360 -104.000 38  5z68_A mol:protein length:373 DNA replication and repair protein RecF
PfamA32U 1-339 -23.900 15  PF13175.6; I1YS32_PREI7/1-378; AAA ATPase domain
SCOP207 1-337 -29.700 17  g1f2t.1 c.37.1.12 (A:,B:) Rad50 {Pyrococcus furiosus [TaxId: 2261]}
VFDB 1-359 -103.000 23  [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
5 gi|238922437|ref|YP_002935950.1| DNA gyrase, B subunit (EUBREC_0005) [Eubacterium rectale ATCC 33656] 645 COG1018 5-645 -151.000 53  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
CSGID 3-645 -200.000 60  IDP04572 DNA gyrase subunit B [Bacillus anthracis str. Sterne] BAS0005 [Bacillus anthracis str. Sterne]
H.sapiens 1-249 -69.700 22  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 1-300)
89-402 -81.600 18  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 151-450)
269-565 -101.000 24  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 301-600)
402-645 -85.600 29  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 451-750)
HGM_OVER 296-641 -2.900 11  PB005684 gi|160884252|ref|ZP_02065255.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]gi|156109991|gb|EDO11736.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]
NEW_HUMAN_DOMAINS 429-503 -6.690 15  sp|Q6IEE8|SN12L_HUMAN Schlafen family member 12-like OS=Homo sapiens GN=SLFN12L PE=2 SV=3 (Range: 1-81)
PDB1018 2-645 -181.000 53  4juo_C mol:protein length:670 DNA topoisomerase 4 subunit B
PfamA32U 41-145 -14.200 16  PF13589.6; A5G4D8_GEOUR/22-165; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
230-400 -59.600 46  PF00204.25; A9KS52_LACP7/226-396; DNA gyrase B
538-638 -37.000 19  PF16898.5; K5XBZ3_PHACS/641-767; C-terminal associated domain of TOPRIM
SCOP207 22-229 -81.300 66  d4k4oa1 d.122.1.0 (A:18-224) automated matches {Enterococcus faecalis [TaxId: 226185]}
230-401 -58.700 44  d1kija1 d.14.1.3 (A:221-392) DNA gyrase B {Thermus thermophilus [TaxId: 274]}
403-636 -51.600 28  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
422-624 -92.600 55  d3m4ia_ e.78.1.1 (A:) DNA gyrase beta-prime domain {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 5-645 -151.000 53  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
6 gi|238922438|ref|YP_002935951.1| DNA gyrase, A subunit (EUBREC_0006) [Eubacterium rectale ATCC 33656] 852 COG1018 3-830 -161.000 43  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
CSGID 3-848 -174.000 48  IDP04555 gene: gyrA; DNA gyrase subunit A [Salmonella typhimurium LT2] STM2272_1_878 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 6-227 -46.900 26  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 601-900)
50-364 -58.300 23  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 751-1050)
232-510 -28.000 12  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 901-1200)
HGM_OVER 12-178 -1.910 14  HGC00690 gi|162868815|dbj|BABB01001192.1|3.0 TMP00870;
NEW_HUMAN_DOMAINS 38-170 -5.370 21  sp|Q9H1B7|I2BPL_HUMAN Interferon regulatory factor 2-binding protein-like OS=Homo sapiens GN=IRF2BPL PE=1 SV=1 (Range: 373-516)
PDB1018 1-493 -123.000 61  2xco_A mol:protein length:726 DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A
31-756 -130.000 37  1zvu_A mol:protein length:716 Topoisomerase IV subunit A
500-810 -41.100 31  1suu_A mol:protein length:312 DNA gyrase subunit A
609-852 -23.400 14  4mn4_A mol:protein length:259 DNA topoisomerase 4 subunit A
PfamA32U 33-465 -66.000 21  PF00521.20; A0A0D1DXS4_USTMA/785-1232; DNA gyrase/topoisomerase IV, subunit A
SCOP207 6-521 -68.100 16  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
31-493 -115.000 52  d3ilwa_ e.11.1.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
507-809 -40.000 31  d1suua_ b.68.10.1 (A:) DNA gyrase A C-terminal domain {Lyme disease spirochete (Borrelia burgdorferi) [TaxId: 139]}
VFDB 3-830 -161.000 43  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
7 gi|238922439|ref|YP_002935952.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (EUBREC_0007) [Eubacterium rectale ATCC 33656] 281 COG1018 8-281 -94.300 27  [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
CSGID 2-281 -82.700 27  IDP01694 gene: fumA; fumarate hydratase, class I [Yersinia pestis CO92] YPO3335 [Yersinia pestis CO92]
H.sapiens 184-281 -8.500 15  sp|Q86WS3|PLACL_HUMAN(removed signalp:1-17) Placenta-specific 1-like protein OS=Homo sapiens GN=PLAC1L PE=2 SV=1
HGM_OVER 2-109 -4.470 HGC00573 gi|163306732|dbj|BABD01003960.1|2.0 TMP00669;
NEW_HUMAN_DOMAINS 1-268 -5.710 12  sp|Q9Y2V0|CO041_HUMAN Uncharacterized protein C15orf41 OS=Homo sapiens GN=C15orf41 PE=2 SV=2 (Range: 1-281)
PDB1018 2-281 -81.600 26  5l2r_A mol:protein length:604 Fumarate hydratase
PfamA32U 11-278 -105.000 55  PF05681.14; H3K4A5_9FIRM/11-279; Fumarate hydratase (Fumerase)
SCOP207 26-232 -7.340 12  d1ijba_ c.62.1.1 (A:) von Willebrand factor A1 domain, vWA1 {Human (Homo sapiens) [TaxId: 9606]}
VFDB 8-281 -94.300 27  [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
8 gi|238922440|ref|YP_002935953.1| hypothetical protein (EUBREC_0008) [Eubacterium rectale ATCC 33656] 47 COG1018 11-47 -4.490 16  [KT] COG3835 Sugar diacid utilization regulator
CSGID 27-46 -6.200 25  IDP00603 gene: sarX; staphylococcal accessory protein X SACOL0726 [Staphylococcus aureus subsp. aureus COL]
H.sapiens 12-41 -7.660 32  sp|Q16821|PPR3A_HUMAN Protein phosphatase 1 regulatory subunit 3A OS=Homo sapiens GN=PPP1R3A PE=1 SV=3 (Range: 901-1122)
HGM_OVER 17-46 -1.850 13  PB009534 gi|153852721|ref|ZP_01994158.1| hypothetical protein DORLON_00140 [Dorea longicatena DSM 13814]gi|149754363|gb|EDM64294.1| hypothetical protein DORLON_00140 [Dorea longicatena DSM 13814]
NEW_HUMAN_DOMAINS 25-38 -6.670 42  sp|Q5VYV7|CT094_HUMAN UPF0492 protein C20orf94 OS=Homo sapiens GN=C20orf94 PE=1 SV=1 (Range: 1-54)
PDB1018 1-22 -6.280 31  6fti_1 mol:protein length:162 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1,RPN1
PfamA32U 16-43 -6.250 21  PF18004.1; H0EIK8_GLAL7/868-1046; 26S proteasome regulatory subunit RPN2 C-terminal domain
SCOP207 9-43 -4.660 12  d4adya3 b.3.8.1 (A:754-925) Proteasome regulatory subunit Rpn2, C-terminal domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 11-47 -4.490 16  [KT] COG3835 Sugar diacid utilization regulator
9 gi|238922441|ref|YP_002935954.1| fumarate hydratase subunit B (EUBREC_0009) [Eubacterium rectale ATCC 33656] 183 COG1018 1-182 -86.300 37  [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
CSGID 1-182 -71.700 43  IDP02526 gene: fumA; fumerate hydratase [Francisella tularensis subsp. tularensis SCHU S4] FTT1600c [Francisella tularensis subsp. tularensis SCHU S4]
H.sapiens 5-158 -6.620 sp|A4D1Z8|GRIFN_HUMAN Putative grifin OS=Homo sapiens GN=GRIFIN PE=5 SV=3
HGM_OVER 6-59 -2.850 11  PB008806 Q5L9W8_BACFN/1-127 PB008806; Pfam-B_8806;
NEW_HUMAN_DOMAINS 119-169 -5.260 13  sp|Q6P2C0|WDR93_HUMAN WD repeat-containing protein 93 OS=Homo sapiens GN=WDR93 PE=2 SV=1 (Range: 101-233)
PDB1018 1-175 -81.100 41  2isb_A mol:protein length:192 Fumarase
PfamA32U 1-175 -84.400 38  PF05683.12; W4Y8Y1_STRPU/30-236; Fumarase C-terminus
SCOP207 1-174 -82.000 41  d1vpja_ c.8.9.1 (A:) Fumarate hydratase class I beta subunit {Archaeoglobus fulgidus [TaxId: 2234]}
VFDB 1-182 -86.300 37  [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
10 gi|238922442|ref|YP_002935955.1| putative oxidoreductase (EUBREC_0016) [Eubacterium rectale ATCC 33656] 329 COG1018 2-329 -84.800 18  [GQ] KOG2741 Dimeric dihydrodiol dehydrogenase
CSGID 2-329 -55.200 16  IDP02458 putative oxidoreductase [Yersinia pestis CO92] YPO2259 [Yersinia pestis CO92]
H.sapiens 22-329 -102.000 26  sp|Q9UQ10|DHDH_HUMAN(removed signalp:1-23) Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase OS=Homo sapiens GN=DHDH PE=1 SV=1
HGM_OVER 118-243 -2.840 13  PB001025 Q1QFV3_NITHX/1-288 PB001025; Pfam-B_1025;
NEW_HUMAN_DOMAINS 32-114 -5.080 18  sp|A2RRP1|NBAS_HUMAN Neuroblastoma-amplified sequence OS=Homo sapiens GN=NBAS PE=1 SV=2 (Range: 483-641)
PDB1018 3-329 -105.000 24  2o48_X mol:protein length:334 Dimeric dihydrodiol dehydrogenase
PfamA32U 4-122 -31.800 16  PF01408.22; YEAH_SCHPO/36-187; Oxidoreductase family, NAD-binding Rossmann fold
134-240 -21.200 16  PF02894.17; IOLW_BACSU/143-250; Oxidoreductase family, C-terminal alpha/beta domain
SCOP207 3-185 -70.100 24  d2q4ea1 c.2.1.3 (A:6-133,A:305-360) Probable oxidoreductase At4g09670 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
127-290 -42.600 17  d2q4ea2 d.81.1.5 (A:134-304) Probable oxidoreductase At4g09670 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
VFDB 2-329 -84.800 18  [GQ] KOG2741 Dimeric dihydrodiol dehydrogenase
11 gi|238922443|ref|YP_002935956.1| transcription repressor of fructose operon FruR (EUBREC_0017) [Eubacterium rectale ATCC 33656] 247 COG1018 1-247 -79.800 27  [KG] COG1349 Transcriptional regulators of sugar metabolism
CSGID 1-247 -80.500 23  IDP00219 probable deoR-family transcriptional regulatory protein YPO1938 [Yersinia pestis CO92]
H.sapiens 79-212 -11.200 16  sp|P49247|RPIA_HUMAN Ribose-5-phosphate isomerase OS=Homo sapiens GN=RPIA PE=1 SV=3
HGM_OVER 1-138 -7.130 14  PB001025 Q1QFV3_NITHX/1-288 PB001025; Pfam-B_1025;
NEW_HUMAN_DOMAINS 5-50 -6.390 13  sp|Q12789|TF3C1_HUMAN General transcription factor 3C polypeptide 1 OS=Homo sapiens GN=GTF3C1 PE=1 SV=4 (Range: 615-711)
PDB1018 1-57 -20.400 21  4hob_A mol:protein length:69 Putative uncharacterized protein
1-110 -16.200 20  1j5y_A mol:protein length:187 TRANSCRIPTIONAL REGULATOR, BIOTIN REPRESSOR FAMILY
54-212 -14.200 12  3enq_A mol:protein length:235 Ribose-5-phosphate isomerase A
PfamA32U 1-126 -32.500 11  PF06163.11; A0A070SGS2_ECOLX/1-127; Bacterial protein of unknown function (DUF977 topsan)
76-232 -58.400 26  PF00455.22; A9CFA5_AGRFC/78-235; DeoR C terminal sensor domain
SCOP207 7-55 -17.000 16  d2htja1 a.4.5.73 (A:1-73) P fimbrial regulatory protein PapI {Escherichia coli [TaxId: 562]}
77-226 -34.700 12  d1lk5a1 c.124.1.4 (A:1-130,A:211-229) D-ribose-5-phosphate isomerase (RpiA), catalytic domain {Pyrococcus horikoshii [TaxId: 53953]}
VFDB 1-247 -79.800 27  [KG] COG1349 Transcriptional regulators of sugar metabolism
12 gi|238922444|ref|YP_002935957.1| fructose-1-phosphate kinase (EUBREC_0018) [Eubacterium rectale ATCC 33656] 305 COG1018 1-304 -84.600 26  [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
CSGID 1-304 -85.800 29  IDP02618 gene: fruK; 1-phosphofructokinase [Salmonella typhimurium LT2] STM2205 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 3-297 -33.900 15  sp|Q9H477|RBSK_HUMAN Ribokinase OS=Homo sapiens GN=RBKS PE=1 SV=1
HGM_OVER 90-252 -3.280 11  PB021133 Q64YN4_BACFR/1-310 PB021133; Pfam-B_21133;
NEW_HUMAN_DOMAINS 130-254 -5.950 tr|Q49A14|Q49A14_HUMAN CCDC108 protein OS=Homo sapiens GN=CCDC108 PE=2 SV=1 (Range: 1-123)
PDB1018 1-304 -91.100 44  2abq_A mol:protein length:306 fructose 1-phosphate kinase
PfamA32U 11-286 -31.000 14  PF00294.24; ADK_YEAST/21-336; pfkB family carbohydrate kinase
SCOP207 1-304 -91.000 43  d2jg5a_ c.72.1.0 (A:) automated matches {Staphylococcus aureus [TaxId: 1280]}
VFDB 1-304 -84.600 26  [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
13 gi|238922445|ref|YP_002935958.1| PTS system, fructose-specific, IIABC component (EUBREC_0019) [Eubacterium rectale ATCC 33656] 642 COG1018 6-256 -44.500 20  [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
172-295 -51.300 49  [G] COG1445 Phosphotransferase system fructose-specific component IIB
302-641 -87.800 55  [G] COG1299 Phosphotransferase system, fructose-specific IIC component
CSGID 1-641 -162.000 49  IDP04367 PTS system, fructose-specific IIABC component [Bacillus anthracis str. Sterne] BAS3563 [Bacillus anthracis str. Sterne]
H.sapiens 1-148 -30.500 16  sp|Q8NBS3|S4A11_HUMAN Sodium bicarbonate transporter-like protein 11 OS=Homo sapiens GN=SLC4A11 PE=1 SV=2 (Range: 1-300)
17-271 -13.200 11  sp|P48751|B3A3_HUMAN Anion exchange protein 3 OS=Homo sapiens GN=SLC4A3 PE=1 SV=2 (Range: 451-750)
HGM_OVER 112-276 -4.650 12  PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;
NEW_HUMAN_DOMAINS 181-242 -4.560 17  sp|Q7L0X0|TRIL_HUMAN TLR4 interactor with leucine rich repeats OS=Homo sapiens GN=TRIL PE=1 SV=2 (Range: 720-789)
PDB1018 1-151 -52.400 22  3urr_A mol:protein length:153 PTS IIA-like nitrogen-regulatory protein PtsN
1-636 -12.500 12  4yzf_A mol:protein length:911 Band 3 anion transport protein
173-278 -49.800 50  2r48_A mol:protein length:106 Phosphotransferase system (PTS) mannose-specific enzyme IIBCA component
PfamA32U 5-148 -22.200 21  PF00359.22; Q9KMS5_VIBCH/6-152; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
356-640 -12.700 17  PF13303.6; Q9A1Q9_STRP1/29-336; Phosphotransferase system, EIIC
SCOP207 1-151 -52.700 22  d3urra1 d.112.1.0 (A:1-151) automated matches {Burkholderia thailandensis [TaxId: 271848]}
176-278 -49.400 51  d2r48a1 c.44.2.2 (A:2-104) Mannose-specific enzyme IIBCA component ManP, N-terminal domain {Bacillus subtilis [TaxId: 1423]}
VFDB 6-256 -44.500 20  [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
172-295 -51.300 49  [G] COG1445 Phosphotransferase system fructose-specific component IIB
302-641 -87.800 55  [G] COG1299 Phosphotransferase system, fructose-specific IIC component
14 gi|238922446|ref|YP_002935959.1| chaperone protein DnaK (EUBREC_0020) [Eubacterium rectale ATCC 33656] 586 COG1018 1-585 -154.000 54  [O] COG0443 Molecular chaperone
CSGID 1-586 -159.000 53  IDP06131 gene: dnaK; molecular chaperone DnaK [Helicobacter pylori J99] NP_222822 [Helicobacter pylori J99]
H.sapiens 3-482 -128.000 29  sp|Q0VDF9|HSP7E_HUMAN Heat shock 70 kDa protein 14 OS=Homo sapiens GN=HSPA14 PE=1 SV=1
226-531 -93.900 54  sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial OS=Homo sapiens GN=HSPA9 PE=1 SV=2 (Range: 301-600)
268-568 -83.100 43  sp|P11021|GRP78_HUMAN(removed signalp:1-18) 78 kDa glucose-regulated protein OS=Homo sapiens GN=HSPA5 PE=1 SV=2 (Range: 301-600)
HGM_OVER 91-472 -7.910 10  PB162065 _Gut.Meta.Jp.0089312_ gi|162832207|dbj|BABA01012502.1||1 (- 0:1326~0 complete)
NEW_HUMAN_DOMAINS 327-479 -9.140 15  sp|O43301|HS12A_HUMAN Heat shock 70 kDa protein 12A OS=Homo sapiens GN=HSPA12A PE=1 SV=2 (Range: 520-675)
PDB1018 1-586 -160.000 51  5nro_A mol:protein length:611 Chaperone protein DnaK
PfamA32U 4-586 -162.000 52  PF00012.20; HSP7E_DROME/54-653; Hsp70 protein
SCOP207 3-160 -72.400 58  d3i33a1 c.55.1.1 (A:6-189) automated matches {Human (Homo sapiens) [TaxId: 9606]}
158-353 -75.800 42  d3i33a2 c.55.1.1 (A:190-384) automated matches {Human (Homo sapiens) [TaxId: 9606]}
366-483 -59.100 65  d4f01a1 b.130.1.1 (A:389-506) automated matches {Escherichia coli K-12 [TaxId: 83333]}
484-586 -19.700 18  d4f01a2 a.8.4.1 (A:507-602) automated matches {Escherichia coli K-12 [TaxId: 83333]}
VFDB 1-585 -154.000 54  [O] COG0443 Molecular chaperone
15 gi|238922447|ref|YP_002935960.1| hypothetical protein (EUBREC_0021) [Eubacterium rectale ATCC 33656] 290 COG1018 3-139 -11.000 15  [D] COG3599 Cell division initiation protein
CSGID 3-141 -11.200 IDP04265 putative cell division protein DivIVA [Clostridium perfringens ATCC 13124] CPF_2105 [Clostridium perfringens ATCC 13124]
34-151 -14.200 12  IDP06542 gene: divIVA; cell division initiation protein DivIVA [Enterococcus faecium DO] AFK58425 [Enterococcus faecium DO]
H.sapiens 2-173 -8.770 12  sp|Q13751|LAMB3_HUMAN(removed signalp:1-17) Laminin subunit beta-3 OS=Homo sapiens GN=LAMB3 PE=1 SV=1 (Range: 751-1050)
HGM_OVER 2-127 -4.270 14  PB202086 Q8G498_BIFLO/2-200 PB202086; Pfam-B_202086;
NEW_HUMAN_DOMAINS 2-128 -5.470 sp|P04114|APOB_HUMAN Apolipoprotein B-100 OS=Homo sapiens GN=APOB PE=1 SV=2 (Range: 1680-2256)
PDB1018 36-138 -11.000 11  6fkf_p mol:protein length:222 ATP synthase subunit b`, chloroplastic
PfamA32U 3-128 -10.700 PF05103.13; Q8E178_STRA5/3-143; DivIVA protein
SCOP207 64-127 -8.050 11  d1l2pa_ f.23.21.1 (A:) F1F0 ATP synthase subunit B, membrane domain {Escherichia coli [TaxId: 562]}
VFDB 3-139 -11.000 15  [D] COG3599 Cell division initiation protein
16 gi|238922448|ref|YP_002935961.1| DNA-binding response regulator (EUBREC_0022) [Eubacterium rectale ATCC 33656] 230 COG1018 2-229 -98.000 35  [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CSGID 2-228 -104.000 48  IDP91043 gene: vanRG; response regulator [Enterococcus faecalis] EFE0003 [Enterococcus faecalis]
H.sapiens 3-156 -30.100 12  sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2 (Range: 1-300)
3-205 -21.800 11  sp|O60658|PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8A OS=Homo sapiens GN=PDE8A PE=1 SV=2 (Range: 1-300)
HGM_OVER 57-153 -3.660 14  PB039305 _Gut.Meta.Jp.0057508_ gi|162726131|dbj|BAAY01002830.1||2 (- 1092:1581~0 complete)
NEW_HUMAN_DOMAINS 1-129 -32.800 12  sp|Q9NX45|SOLH2_HUMAN Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 OS=Homo sapiens GN=SOHLH2 PE=2 SV=2 (Range: 1-196)
PDB1018 2-230 -102.000 36  2gwr_A mol:protein length:238 DNA-binding response regulator mtrA
PfamA32U 2-212 -52.200 14  PF01993.18; F6D7B4_METPW/3-276; methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase
SCOP207 2-119 -62.900 31  d2qzja_ c.23.1.0 (A:) automated matches {Clostridium difficile [TaxId: 272563]}
2-169 -54.500 17  d3rqia_ c.23.1.0 (A:) automated matches {Burkholderia pseudomallei [TaxId: 320372]}
130-230 -47.900 33  d4ixaa_ a.4.6.0 (A:) automated matches {Staphylococcus epidermidis [TaxId: 176280]}
VFDB 2-229 -98.000 35  [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
17 gi|238922449|ref|YP_002935962.1|(removed signalp:1-29) hypothetical protein (EUBREC_0023) [Eubacterium rectale ATCC 33656] 428 COG1018 125-427 -52.500 17  [T] COG0642 Signal transduction histidine kinase
CSGID 24-427 -78.000 32  IDP04550 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0460 [Clostridium perfringens ATCC 13124]
H.sapiens 152-428 -22.200 13  sp|Q16654|PDK4_HUMAN [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial OS=Homo sapiens GN=PDK4 PE=1 SV=1
HGM_OVER 169-390 -3.710 10  PB021133 Q64YN4_BACFR/1-310 PB021133; Pfam-B_21133;
NEW_HUMAN_DOMAINS 151-404 -6.400 sp|Q5CZC0|FSIP2_HUMAN Fibrous sheath-interacting protein 2 OS=Homo sapiens GN=FSIP2 PE=1 SV=4 (Range: 4508-4797)
PDB1018 126-427 -48.200 18  4biu_A mol:protein length:298 SENSOR PROTEIN CPXA
176-427 -49.200 22  4q20_A mol:protein length:268 Sensor protein DivL
PfamA32U 206-270 -15.100 23  PF00512.25; Q55783_SYNY3/185-253; His Kinase A (phospho-acceptor) domain
318-428 -24.700 28  PF02518.26; O52937_9CYAN/626-739; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SCOP207 192-273 -22.000 23  d2c2aa1 a.30.2.1 (A:232-320) Sensor histidine kinase TM0853 {Thermotoga maritima [TaxId: 2336]}
271-427 -31.700 22  d1bxda_ d.122.1.3 (A:) Histidine kinase domain of the osmosensor EnvZ {Escherichia coli [TaxId: 562]}
VFDB 125-427 -52.500 17  [T] COG0642 Signal transduction histidine kinase
18 gi|238922450|ref|YP_002935963.1| hypothetical protein (EUBREC_0024) [Eubacterium rectale ATCC 33656] 761 COG1018 1-761 -156.000 18  [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase superfamily)
CSGID 10-761 -150.000 18  IDP02220 gene: acnA; aconitate hydratase [Yersinia pestis CO92] YPO2221 [Yersinia pestis CO92]
H.sapiens 24-265 -68.600 25  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 1-300)
56-312 -71.700 23  sp|P48200|IREB2_HUMAN Iron-responsive element-binding protein 2 OS=Homo sapiens GN=IREB2 PE=1 SV=3 (Range: 151-450)
116-431 -88.300 26  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 151-450)
266-566 -66.100 18  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 301-600)
432-733 -51.800 17  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 451-750)
HGM_OVER 348-455 -2.760 12  HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
NEW_HUMAN_DOMAINS 120-275 -4.780 sp|Q8IX21|F178A_HUMAN Protein FAM178A OS=Homo sapiens GN=FAM178A PE=1 SV=2 (Range: 727-883)
PDB1018 5-761 -152.000 19  2b3x_A mol:protein length:888 Iron-responsive element binding protein 1
PfamA32U 47-479 -104.000 21  PF00330.20; D2R1Y9_PIRSD/11-461; Aconitase family (aconitate hydratase)
549-695 -37.600 21  PF00694.19; ACON_BOVIN/582-712; Aconitase C-terminal domain
549-761 -30.800 14  PF06434.13; Q01EA0_OSTTA/235-442; Aconitate hydratase 2 N-terminus
SCOP207 5-525 -111.000 19  d2b3ya2 c.83.1.1 (A:2-630) Iron-responsive element binding protein 1, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
515-761 -45.200 19  d2b3ya1 c.8.2.1 (A:631-889) ron-responsive element binding protein 1, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-761 -156.000 18  [AJ] KOG0452 RNA-binding translational regulator IRP (aconitase superfamily)
19 gi|238922451|ref|YP_002935964.1| hypothetical protein (EUBREC_0025) [Eubacterium rectale ATCC 33656] 437 COG1018 52-426 -54.600 16  [R] COG0628 Predicted permease
CSGID 282-404 -5.380 13  IDP95412 set236a-014 [Undefined organism]
H.sapiens 181-437 -22.700 12  sp|Q9H330|CI005_HUMAN Transmembrane protein C9orf5 OS=Homo sapiens GN=C9orf5 PE=1 SV=2 (Range: 601-900)
HGM_OVER 232-389 -6.590 HGC00928 gi|162868028|dbj|BABB01001979.1|3.0 TMP01255;
NEW_HUMAN_DOMAINS 259-372 -6.890 12  sp|Q0VDI3|CE028_HUMAN Transmembrane protein C5orf28 OS=Homo sapiens GN=C5orf28 PE=2 SV=1 (Range: 1-112)
PDB1018 294-388 -8.160 19  3rlb_A mol:protein length:192 ThiT
PfamA32U 53-404 -57.400 18  PF01594.16; Y338_HAEIN/10-332; AI-2E family transporter
SCOP207 86-219 -5.420 d1gs9a_ a.24.1.1 (A:) Apolipoprotein E {Human (Homo sapiens), E4 [TaxId: 9606]}
VFDB 52-426 -54.600 16  [R] COG0628 Predicted permease
20 gi|238922452|ref|YP_002935965.1| hypothetical protein (EUBREC_0026) [Eubacterium rectale ATCC 33656] 877 COG1018 9-239 -11.100 12  [DO] KOG1174 Anaphase-promoting complex (APC), subunit 7
10-187 -14.900 15  [R] COG4105 DNA uptake lipoprotein
255-876 -11.000 [L] KOG1514 Origin recognition complex, subunit 1, and related proteins
532-851 -11.900 [L] KOG2028 ATPase related to the helicase subunit of the Holliday junction resolvase
614-847 -16.300 [R] COG2607 Predicted ATPase (AAA+ superfamily)
631-877 -12.800 13  [L] COG2812 DNA polymerase III, gamma/tau subunits
CSGID 1-134 -13.000 12  IDP93896 secretion system chaperone SscA [Yersinia enterocolitica subsp. palearctica Y11] YP_006007024 [Yersinia enterocolitica subsp. palearctica Y11]
1-182 -13.000 12  IDP90425 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_547 [Chlamydia trachomatis D/UW-3/CX]
179-679 -17.600 IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
631-847 -14.700 12  IDP04216 gene: ruvB; Holliday junction DNA helicase B [Salmonella typhimurium LT2] STM1894_1_336 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
631-877 -14.300 16  IDP05235 gene: ruvB; Holliday junction DNA helicase B [Listeria monocytogenes EGD-e] lmo1532 [Listeria monocytogenes EGD-e]
H.sapiens 1-224 -12.000 11  sp|Q9UJX2|CDC23_HUMAN(removed signalp:1-21) Cell division cycle protein 23 homolog OS=Homo sapiens GN=CDC23 PE=1 SV=3
10-196 -15.100 16  sp|Q9Y5Q9|TF3C3_HUMAN General transcription factor 3C polypeptide 3 OS=Homo sapiens GN=GTF3C3 PE=1 SV=1 (Range: 151-450)
22-264 -11.800 11  sp|O15550|KDM6A_HUMAN Lysine-specific demethylase 6A OS=Homo sapiens GN=KDM6A PE=1 SV=2 (Range: 301-600)
472-851 -12.200 10  sp|Q99741|CDC6_HUMAN Cell division control protein 6 homolog OS=Homo sapiens GN=CDC6 PE=1 SV=1
549-840 -13.300 11  sp|Q96S55|WRIP1_HUMAN ATPase WRNIP1 OS=Homo sapiens GN=WRNIP1 PE=1 SV=2 (Range: 151-450)
603-867 -13.500 14  sp|P40937|RFC5_HUMAN Replication factor C subunit 5 OS=Homo sapiens GN=RFC5 PE=1 SV=1
620-847 -14.600 11  sp|Q9NVI7|ATD3A_HUMAN ATPase family AAA domain-containing protein 3A OS=Homo sapiens GN=ATAD3A PE=1 SV=2 (Range: 301-600)
HGM_OVER 643-876 -4.750 12  PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;
NEW_HUMAN_DOMAINS 47-155 -10.400 16  tr|F5H535|F5H535_HUMAN Uncharacterized protein OS=Homo sapiens GN=TAF1A PE=4 SV=1 (Range: 171-282)
PDB1018 2-187 -15.400 15  5waq_A mol:protein length:251 Outer membrane protein assembly factor BamD
2-859 -12.600 5yfp_A mol:protein length:1336 Exocyst complex component SEC3
606-876 -41.400 17  3syk_A mol:protein length:309 Protein CbbX
PfamA32U 8-169 -11.400 12  PF16918.5; V9XE69_9NOCA/412-767; Protein kinase G tetratricopeptide repeat
16-288 -10.500 13  PF12569.8; A7S752_NEMVE/188-686; NMDA receptor-regulated protein 1
25-769 -10.400 PF17825.1; G1PD96_MYOLU/1-1455; Family of unknown function (DUF5587 topsan)
39-198 -14.000 16  PF13525.6; D3V9W2_XENNA/28-237; Outer membrane lipoprotein
633-844 -16.000 10  PF05673.13; Q0K6N5_CUPNH/29-287; Protein of unknown function (DUF815 topsan)
SCOP207 3-190 -9.620 13  d1xnfa_ a.118.8.1 (A:) Lipoprotein NlpI {Escherichia coli [TaxId: 562]}
16-170 -12.100 12  d2vsna1 a.118.8.1 (A:22-192) O-GlcNAc transferase, OGT {Xanthomonas campestris [TaxId: 314565]}
631-876 -15.200 13  d1in4a2 c.37.1.20 (A:17-254) Holliday junction helicase RuvB {Thermotoga maritima [TaxId: 2336]}
VFDB 9-239 -11.100 12  [DO] KOG1174 Anaphase-promoting complex (APC), subunit 7
10-187 -14.900 15  [R] COG4105 DNA uptake lipoprotein
255-876 -11.000 [L] KOG1514 Origin recognition complex, subunit 1, and related proteins
532-851 -11.900 [L] KOG2028 ATPase related to the helicase subunit of the Holliday junction resolvase
614-847 -16.300 [R] COG2607 Predicted ATPase (AAA+ superfamily)
631-877 -12.800 13  [L] COG2812 DNA polymerase III, gamma/tau subunits


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Slabinski L, Jaroszewski L, Rodrigues AP, Rychlewski L, Wilson IA, Lesley SA, Godzik A. The challenge of protein structure determination--lessons from structuralgenomics. Protein Sci. 2007 Nov;16(11):2472-82.