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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|15607143|ref|NP_214515.1| chromosomal replication initiation protein (Rv0001) [Mycobacterium tuberculosis H37Rv] 507 COG1018 8-503 -117.000 34  [L] COG0593 ATPase involved in DNA replication initiation
CSGID 6-502 -117.000 47  IDP00004 Chromosomal replication initiator protein dnaA BA_0001 [Bacillus anthracis str. Ames]
H.sapiens 102-379 -11.300 15  sp|Q96S55|WRIP1_HUMAN ATPase WRNIP1 OS=Homo sapiens GN=WRNIP1 PE=1 SV=2 (Range: 151-450)
178-500 -13.100 11  sp|Q99741|CDC6_HUMAN Cell division control protein 6 homolog OS=Homo sapiens GN=CDC6 PE=1 SV=1
204-422 -14.300 16  sp|Q6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 OS=Homo sapiens GN=ATAD2 PE=1 SV=1 (Range: 451-750)
HGM_OVER 166-495 -3.390 10  PB005684 gi|160884252|ref|ZP_02065255.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]gi|156109991|gb|EDO11736.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]
NEW_HUMAN_DOMAINS 236-433 -4.750 sp|Q6ZV50|RFX8_HUMAN DNA-binding protein RFX8 OS=Homo sapiens GN=RFX8 PE=2 SV=2 (Range: 148-329)
PDB1018 12-507 -112.000 31  2z4r_A mol:protein length:440 Chromosomal replication initiator protein dnaA
PfamA32U 10-88 -12.000 28  PF11638.8; DNAA_LAWIP/5-67; DnaA N-terminal domain
168-386 -93.000 79  PF00308.18; DNAA_STRCO/317-535; Bacterial dnaA protein
204-507 -10.600 14  PF03969.16; ZAPE_ECOLI/4-371; AFG1-like ATPase
413-480 -29.800 51  PF08299.11; D9QS97_ACEAZ/358-426; Bacterial dnaA protein helix-turn-helix
SCOP207 166-381 -87.000 39  d1l8qa2 c.37.1.20 (A:77-289) Chromosomal replication initiation factor DnaA {Aquifex aeolicus [TaxId: 63363]}
398-504 -38.000 28  d1l8qa1 a.4.12.2 (A:290-399) Chromosomal replication initiation factor DnaA C-terminal domain IV {Aquifex aeolicus [TaxId: 63363]}
VFDB 8-503 -117.000 34  [L] COG0593 ATPase involved in DNA replication initiation
2 gi|15607144|ref|NP_214516.1| DNA polymerase III subunit beta (Rv0002) [Mycobacterium tuberculosis H37Rv] 402 COG1018 13-402 -95.500 24  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
CSGID 13-400 -97.100 29  IDP90614 DNA polymerase III subunit beta [Vibrio cholerae O1 biovar eltor str. N16961] VC0013 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 140-366 -10.700 14  sp|P12004|PCNA_HUMAN Proliferating cell nuclear antigen OS=Homo sapiens GN=PCNA PE=1 SV=1
HGM_OVER 19-359 -5.380 10  PB004476 gi|139436894|ref|ZP_01771054.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]gi|133776541|gb|EBA40361.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]
NEW_HUMAN_DOMAINS 40-133 -6.470 sp|Q04912|RON_HUMAN Macrophage-stimulating protein receptor OS=Homo sapiens GN=MST1R PE=1 SV=2 (Range: 865-959)
PDB1018 1-402 -114.000 100  3p16_A mol:protein length:408 DNA polymerase III subunit beta
PfamA32U 13-129 -49.500 25  PF00712.19; DPO3B_CAUVC/1-121; DNA polymerase III beta subunit, N-terminal domain
138-260 -45.700 22  PF02767.16; DPO3B_PSEPK/129-244; DNA polymerase III beta subunit, central domain
262-399 -43.300 26  PF02768.15; DPO3B_BACSU/253-376; DNA polymerase III beta subunit, C-terminal domain
SCOP207 13-132 -51.600 20  d5w7za1 d.131.1.0 (A:1-122) automated matches {Rickettsia conorii [TaxId: 272944]}
133-261 -46.900 25  d4k3la2 d.131.1.1 (A:123-244) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
262-401 -49.300 27  d1vpka3 d.131.1.1 (A:244-366) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
VFDB 13-402 -95.500 24  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
3 gi|15607145|ref|NP_214517.1| recombination protein F (Rv0003) [Mycobacterium tuberculosis H37Rv] 385 COG1018 1-377 -101.000 24  [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
CSGID 1-377 -101.000 25  IDP00109 gene: recF; Rec protein NT01SF4517 [Shigella flexneri 2a str. 2457T]
H.sapiens 1-261 -18.600 12  sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 OS=Homo sapiens GN=RAD50 PE=1 SV=1 (Range: 1-300)
136-373 -11.400 13  sp|Q9UQE7|SMC3_HUMAN Structural maintenance of chromosomes protein 3 OS=Homo sapiens GN=SMC3 PE=1 SV=2 (Range: 901-1200)
HGM_OVER 195-372 -2.940 11  PB062763 Q9F6U5_BACTN/1-245 PB062763; Pfam-B_62763;
NEW_HUMAN_DOMAINS 237-327 -4.790 18  tr|E9PBY9|E9PBY9_HUMAN Uncharacterized protein OS=Homo sapiens GN=C10orf93 PE=4 SV=1 (Range: 41-150)
PDB1018 1-377 -103.000 25  5z68_A mol:protein length:373 DNA replication and repair protein RecF
PfamA32U 1-359 -24.100 PF13175.6; I1YS32_PREI7/1-378; AAA ATPase domain
SCOP207 1-381 -30.800 19  g1f2t.1 c.37.1.12 (A:,B:) Rad50 {Pyrococcus furiosus [TaxId: 2261]}
VFDB 1-377 -101.000 24  [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
4 gi|15607146|ref|NP_214518.1| hypothetical protein (Rv0004) [Mycobacterium tuberculosis H37Rv] 187 COG1018 1-187 -80.100 70  [R] COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives
CSGID 52-165 -42.200 14  IDP90373 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_191 [Chlamydia trachomatis D/UW-3/CX]
H.sapiens 1-160 -7.450 12  sp|Q969I6|S38A4_HUMAN Sodium-coupled neutral amino acid transporter 4 OS=Homo sapiens GN=SLC38A4 PE=1 SV=1
HGM_OVER 77-186 -4.780 14  PB047496 gi|150008556|ref|YP_001303299.1| hypothetical protein BDI_1942 [Parabacteroides distasonis ATCC 8503]gi|149936980|gb|ABR43677.1| conserved hypothetical protein [Parabacteroides distasonis ATCC 8503]
NEW_HUMAN_DOMAINS 23-163 -6.640 11  sp|Q7Z4N2|TRPM1_HUMAN Transient receptor potential cation channel subfamily M member 1 OS=Homo sapiens GN=TRPM1 PE=1 SV=2 (Range: 611-769)
PDB1018 74-143 -8.710 14  3bvc_A mol:protein length:212 Uncharacterized protein Ism_01780
PfamA32U 75-162 -37.500 25  PF05258.12; Q02A53_SOLUE/3-88; Dna[CI] antecedent, DciA
SCOP207 100-160 -6.980 13  d1csei_ d.40.1.1 (I:) Eglin C {Medicinal leech (Hirudo medicinalis) [TaxId: 6421]}
VFDB 1-187 -80.100 70  [R] COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives
5 gi|15607147|ref|NP_214519.1| DNA gyrase subunit B (Rv0005) [Mycobacterium tuberculosis H37Rv] 714 COG1018 10-595 -10.600 11  [O] KOG0020 Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family
44-714 -154.000 49  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
CSGID 5-714 -82.600 34  IDP92137 DNA gyrase subunit B, putative [Toxoplasma gondii ME49] TGME49_097780 [Toxoplasma gondii ME49]
37-714 -192.000 51  IDP02606 gene: gyrB; DNA gyrase subunit B [Listeria monocytogenes EGD-e] lmo0006 [Listeria monocytogenes EGD-e]
H.sapiens 4-268 -75.200 19  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 1-300)
128-467 -75.500 14  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 151-450)
334-628 -95.300 19  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 301-600)
468-714 -79.500 25  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 451-750)
HGM_OVER 33-607 -2.990 PB002770 Q744K2_MYCPA/1-559 PB002770; Pfam-B_2770;
NEW_HUMAN_DOMAINS 496-592 -6.830 19  sp|Q14703|MBTP1_HUMAN Membrane-bound transcription factor site-1 protease OS=Homo sapiens GN=MBTPS1 PE=1 SV=1 (Range: 764-875)
PDB1018 29-714 -187.000 46  4juo_C mol:protein length:670 DNA topoisomerase 4 subunit B
PfamA32U 80-183 -13.700 20  PF13589.6; A5G4D8_GEOUR/22-165; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
295-465 -58.700 43  PF00204.25; A9KS52_LACP7/226-396; DNA gyrase B
603-707 -28.100 11  PF16898.5; K5XBZ3_PHACS/641-767; C-terminal associated domain of TOPRIM
641-703 -31.500 60  PF00986.21; M9X0E0_MANHA/738-800; DNA gyrase B subunit, carboxyl terminus
SCOP207 61-260 -85.200 52  d4k4oa1 d.122.1.0 (A:18-224) automated matches {Enterococcus faecalis [TaxId: 226185]}
295-466 -58.500 45  d1kija1 d.14.1.3 (A:221-392) DNA gyrase B {Thermus thermophilus [TaxId: 274]}
468-705 -49.100 26  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
487-693 -94.100 100  d3m4ia_ e.78.1.1 (A:) DNA gyrase beta-prime domain {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 10-595 -10.600 11  [O] KOG0020 Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family
44-714 -154.000 49  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
6 gi|15607148|ref|NP_214520.1| DNA gyrase subunit A (Rv0006) [Mycobacterium tuberculosis H37Rv] 838 COG1018 10-838 -159.000 40  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
CSGID 9-838 -167.000 46  IDP90834 DNA gyrase, subunit A [Vibrio cholerae O1 biovar eltor str. N16961] VC1258 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 12-233 -46.100 24  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 601-900)
56-371 -56.100 21  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 751-1050)
238-495 -24.400 14  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 901-1200)
HGM_OVER 1-178 -2.600 10  HGC00164 gi|163636082|dbj|BABG01000191.1|4.0 TMP00833;
NEW_HUMAN_DOMAINS 44-176 -5.110 18  sp|Q9H1B7|I2BPL_HUMAN Interferon regulatory factor 2-binding protein-like OS=Homo sapiens GN=IRF2BPL PE=1 SV=1 (Range: 373-516)
PDB1018 1-502 -120.000 99  3ifz_A mol:protein length:508 DNA gyrase subunit A
37-765 -125.000 32  1zvu_A mol:protein length:716 Topoisomerase IV subunit A
512-838 -41.600 99  3uc1_A mol:protein length:327 DNA gyrase subunit A
PfamA32U 39-478 -62.400 19  PF00521.20; A0A0D1DXS4_USTMA/785-1232; DNA gyrase/topoisomerase IV, subunit A
SCOP207 3-495 -64.400 16  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
37-499 -112.000 100  d3ilwa_ e.11.1.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
512-820 -40.100 100  d4g3na_ b.68.10.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
VFDB 10-838 -159.000 40  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
7 gi|15607149|ref|NP_214521.1| hypothetical protein (Rv0007) [Mycobacterium tuberculosis H37Rv] 304 COG1018 1-304 -10.200 [K] KOG3915 Transcription regulator dachshund, contains SKI/SNO domain
2-198 -11.000 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
CSGID 1-294 -11.300 10  IDP91949 pneumococcal histidine triad protein E [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100007099 [Streptococcus pneumoniae str. Canada MDR_19A]
H.sapiens 2-287 -10.200 10  sp|Q13563|PKD2_HUMAN Polycystin-2 OS=Homo sapiens GN=PKD2 PE=1 SV=3 (Range: 1-300)
72-302 -10.600 12  sp|Q3KNS1|PTHD3_HUMAN Patched domain-containing protein 3 OS=Homo sapiens GN=PTCHD3 PE=1 SV=2 (Range: 1-300)
HGM_OVER 188-304 -5.160 16  PB002104 Q72PH8_LEPIC/1-220 PB002104; Pfam-B_2104;
NEW_HUMAN_DOMAINS 192-287 -6.520 10  sp|Q96AG3|S2546_HUMAN Solute carrier family 25 member 46 OS=Homo sapiens GN=SLC25A46 PE=1 SV=1 (Range: 171-293)
PDB1018 200-287 -9.060 13  3vou_A mol:protein length:148 Ion transport 2 domain protein, Voltage-gated sodium channel
PfamA32U 186-302 -49.900 60  PF12089.8; Q0SAF2_RHOJR/351-465; Transmembrane domain of unknown function (DUF3566 topsan)
SCOP207 206-285 -6.930 11  d1lnqa2 f.14.1.1 (A:19-98) Potassium channel-related protein MthK {Methanothermobacter thermautotrophicus [TaxId: 145262]}
VFDB 1-304 -10.200 [K] KOG3915 Transcription regulator dachshund, contains SKI/SNO domain
2-198 -11.000 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
8 gi|15607150|ref|NP_214522.1| hypothetical protein (Rv0008c) [Mycobacterium tuberculosis H37Rv] 145 COG1018 1-128 -7.330 13  [R] COG5643 Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E
CSGID 7-133 -6.430 26  IDP90283 gene: GRA6; granule antigen protein GRA6 [Toxoplasma gondii] TGME49_075440 [Toxoplasma gondii]
H.sapiens 99-145 -8.100 21  sp|Q9HBG7|LY9_HUMAN T-lymphocyte surface antigen Ly-9 OS=Homo sapiens GN=LY9 PE=1 SV=3 (Range: 451-655)
HGM_OVER 85-144 -5.470 26  PB008694 Q9F6U1_BACTN/1-190 PB008694; Pfam-B_8694;
NEW_HUMAN_DOMAINS 86-142 -5.020 10  sp|Q5VWN6|CJ018_HUMAN Uncharacterized protein C10orf18 OS=Homo sapiens GN=C10orf18 PE=1 SV=1 (Range: 1-90)
PDB1018 2-129 -7.450 14  2ah6_A mol:protein length:208 BH1595, unknown conserved protein
PfamA32U 9-145 -92.100 100  PF10814.8; CWSA_MYCTU/9-145; Cell wall synthesis protein CwsA
SCOP207 15-145 -6.770 19  d1zq9a1 c.66.1.24 (A:36-313) Probable dimethyladenosine transferase {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-128 -7.330 13  [R] COG5643 Protein containing a metal-binding domain shared with formylmethanofuran dehydrogenase subunit E
9 gi|15607151|ref|NP_214523.1| iron-regulated peptidyl-prolyl cis-trans isomerase A (Rv0009) [Mycobacterium tuberculosis H37Rv] 182 COG1018 2-181 -86.800 45  [O] KOG0881 Cyclophilin type peptidyl-prolyl cis-trans isomerase
CSGID 13-173 -84.000 41  IDP01228 peptidyl-prolyl cis-trans isomerase, cyclophilin-type BA_4283 [Bacillus anthracis str. Ames]
H.sapiens 4-182 -88.600 46  sp|Q9Y3C6|PPIL1_HUMAN Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens GN=PPIL1 PE=1 SV=1
HGM_OVER 90-175 -3.110 20  PB031792 gi|154174791|ref|YP_001409041.1| flavodoxin family protein [Campylobacter curvus 525.92]gi|112804021|gb|EAU01365.1| flavodoxin family protein [Campylobacter curvus 525.92]
NEW_HUMAN_DOMAINS 54-149 -6.060 13  sp|Q8N2C7|UNC80_HUMAN Protein unc-80 homolog OS=Homo sapiens GN=UNC80 PE=2 SV=2 (Range: 767-872)
PDB1018 1-182 -102.000 99  1w74_A mol:protein length:191 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
PfamA32U 17-169 -56.200 26  PF00160.21; Q7NG65_GLOVI/261-474; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
SCOP207 13-182 -101.000 100  d1w74a_ b.62.1.1 (A:) Peptidyl-prolyl cis-trans isomerase A, PpiA {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 2-181 -86.800 45  [O] KOG0881 Cyclophilin type peptidyl-prolyl cis-trans isomerase
10 gi|15607152|ref|NP_214524.1| hypothetical protein (Rv0010c) [Mycobacterium tuberculosis H37Rv] 141 COG1018 39-132 -9.160 11  [S] COG4687 Uncharacterized protein conserved in bacteria
CSGID 18-141 -6.160 11  IDP95308 hypothetical protein VCA0021 [Vibrio cholerae O1 biovar El Tor str. N16961] NP_232422 [Vibrio cholerae O1 biovar El Tor str. N16961]
H.sapiens 60-130 -8.780 sp|P19823|ITIH2_HUMAN(removed signalp:1-18) Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens GN=ITIH2 PE=1 SV=2 (Range: 751-928)
HGM_OVER 69-141 -3.780 11  PB002776 gi|157737147|ref|YP_001489830.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]gi|157699001|gb|ABV67161.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]
NEW_HUMAN_DOMAINS 33-141 -8.710 sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein OS=Homo sapiens GN=NIPBL PE=1 SV=2 (Range: 2691-2804)
PDB1018 43-141 -7.470 4chj_A mol:protein length:164 IMC SUB-COMPARTMENT PROTEIN ISP3
PfamA32U 3-110 -11.300 12  PF17255.2; A4VVV1_STRSY/5-138; EbsA-like protein
58-134 -19.900 18  PF10756.9; Q5YRV9_NOCFA/80-151; Bacterial PH domain
SCOP207 61-115 -7.110 13  d1h4ra2 b.55.1.5 (A:215-313) Merlin {Human (Homo sapiens) [TaxId: 9606]}
VFDB 39-132 -9.160 11  [S] COG4687 Uncharacterized protein conserved in bacteria
11 gi|15607153|ref|NP_214525.1| putative septation inhibitor protein (Rv0011c) [Mycobacterium tuberculosis H37Rv] 93 COG1018 29-92 -8.430 18  [S] COG5528 Predicted integral membrane protein
CSGID 3-59 -5.620 IDP05012 cell wall surface anchor family protein [Bacillus anthracis str. Ames] BA_5070 [Bacillus anthracis str. Ames]
H.sapiens 4-69 -10.200 15  sp|Q2TAL8|QRIC1_HUMAN Glutamine-rich protein 1 OS=Homo sapiens GN=QRICH1 PE=1 SV=1 (Range: 601-776)
HGM_OVER 37-75 -3.470 10  PB042013 A7V626_BACUN/1-162 PB042013; Pfam-B_42013;
NEW_HUMAN_DOMAINS 16-52 -7.450 24  sp|Q8WU66|TSEAR_HUMAN Protein TSPEAR OS=Homo sapiens GN=TSPEAR PE=2 SV=2 (Range: 257-317)
PDB1018 1-93 -81.600 100  2mmu_A mol:protein length:101 Cell division protein CrgA
PfamA32U 1-93 -47.000 31  PF06781.12; D1BI18_SANKS/1-89; Cell division protein CrgA
SCOP207 6-92 -6.510 12  d4ogqb_ f.32.1.1 (B:) automated matches {Nostoc sp. [TaxId: 103690]}
VFDB 29-92 -8.430 18  [S] COG5528 Predicted integral membrane protein
12 gi|15607154|ref|NP_214526.1| hypothetical protein (Rv0012) [Mycobacterium tuberculosis H37Rv] 262 COG1018 18-250 -68.400 20  [S] COG3879 Uncharacterized protein conserved in bacteria
CSGID 22-256 -70.300 15  IDP05645 hypothetical protein CD3297 [Clostridium difficile 630] CD3297 [Peptoclostridium difficile 630]
H.sapiens 48-245 -7.200 14  sp|Q6GMR7|FAAH2_HUMAN(removed signalp:1-27) Fatty-acid amide hydrolase 2 OS=Homo sapiens GN=FAAH2 PE=2 SV=1
HGM_OVER 26-165 -7.190 13  PB006791 A6TXD6_9CLOT/1-181 PB006791; Pfam-B_6791;
NEW_HUMAN_DOMAINS 84-221 -6.020 10  sp|Q8IUI8|CRLF3_HUMAN Cytokine receptor-like factor 3 OS=Homo sapiens GN=CRLF3 PE=1 SV=2 (Range: 281-442)
PDB1018 86-259 -59.300 28  3gmg_A mol:protein length:170 Uncharacterized protein Rv1825/MT1873
PfamA32U 102-255 -63.000 26  PF05949.12; F6B3E0_DESCC/87-231; Bacterial protein of unknown function (DUF881 topsan)
SCOP207 103-213 -6.750 14  d3nz2a_ b.81.1.0 (A:) automated matches {Vibrio cholerae [TaxId: 243277]}
VFDB 18-250 -68.400 20  [S] COG3879 Uncharacterized protein conserved in bacteria
13 gi|57116682|ref|YP_177615.1| para-aminobenzoate synthase component II (Rv0013) [Mycobacterium tuberculosis H37Rv] 232 COG1018 2-232 -66.600 21  [F] KOG1622 GMP synthase
3-190 -85.300 50  [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
CSGID 1-232 -102.000 100  IDP06559 anthranilate synthase component II [Mycobacterium tuberculosis H37Rv] YP_177615 [Mycobacterium tuberculosis H37Rv]
H.sapiens 2-232 -71.000 21  sp|P49915|GUAA_HUMAN GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens GN=GMPS PE=1 SV=1 (Range: 1-300)
HGM_OVER 36-220 -3.220 HGC00267 gi|163310129|dbj|BABD01000566.1|6.0 TMP00066;
NEW_HUMAN_DOMAINS 62-118 -4.950 14  sp|Q2T9K0|TMM44_HUMAN Transmembrane protein 44 OS=Homo sapiens GN=TMEM44 PE=2 SV=2 (Range: 157-223)
PDB1018 1-205 -83.300 26  2a9v_A mol:protein length:212 GMP synthase
PfamA32U 4-189 -79.400 23  PF00117.28; GUAA_BACSU/10-192; Glutamine amidotransferase class-I
SCOP207 1-193 -83.000 31  d1wl8a1 c.23.16.1 (A:1-188) GMP synthase subunit A, GuaAA {Pyrococcus horikoshii [TaxId: 53953]}
VFDB 2-232 -66.600 21  [F] KOG1622 GMP synthase
3-190 -85.300 50  [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II
14 gi|15607156|ref|NP_214528.1| transmembrane serine/threonine-protein kinase B PKNB (protein kinase B) (STPK B) (Rv0014c) [Mycobacterium tuberculosis H37Rv] 626 COG1018 1-331 -104.000 35  [RTKL] COG0515 Serine/threonine protein kinase
429-626 -52.900 84  [S] COG2815 Uncharacterized protein conserved in bacteria
CSGID 1-626 -138.000 27  IDP06302 serine/threonine protein kinase [Streptococcus pneumoniae TIGR4] NP_346168 [Streptococcus pneumoniae TIGR4]
H.sapiens 4-220 -51.800 26  sp|O15075|DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 OS=Homo sapiens GN=DCLK1 PE=1 SV=2 (Range: 301-600)
34-299 -74.900 15  sp|Q9BXU1|STK31_HUMAN Serine/threonine-protein kinase 31 OS=Homo sapiens GN=STK31 PE=2 SV=2 (Range: 751-1019)
HGM_OVER 136-271 -3.750 HGC00024 gi|162813637|dbj|BABA01031072.1|2.0 TMP01508;
NEW_HUMAN_DOMAINS 176-271 -5.610 24  sp|Q5VZB9|DMRTA_HUMAN Doublesex- and mab-3-related transcription factor A1 OS=Homo sapiens GN=DMRTA1 PE=2 SV=1 (Range: 393-504)
PDB1018 1-308 -112.000 100  1mru_A mol:protein length:311 Probable serine/threonine-protein kinase pknB
4-607 -68.000 11  4ci6_B mol:protein length:643 PROTEIN KINASE YOPO
PfamA32U 11-270 -52.200 22  PF00069.25; KS6A1_MOUSE/407-664; Protein kinase domain
360-422 -16.400 33  PF03793.19; A0A098MZT7_LEPIR/112-183; PASTA domain
SCOP207 1-290 -113.000 99  d3orka1 d.144.1.7 (A:1-290) automated matches {Mycobacterium tuberculosis [TaxId: 419947]}
VFDB 1-331 -104.000 35  [RTKL] COG0515 Serine/threonine protein kinase
429-626 -52.900 84  [S] COG2815 Uncharacterized protein conserved in bacteria
15 gi|15607157|ref|NP_214529.1| transmembrane serine/threonine-protein kinase A PKNA (protein kinase A) (STPK A) (Rv0015c) [Mycobacterium tuberculosis H37Rv] 431 COG1018 4-343 -102.000 29  [RTKL] COG0515 Serine/threonine protein kinase
10-431 -48.300 19  [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase (MAP4K), germinal center kinase family
CSGID 4-427 -101.000 28  IDP06302 serine/threonine protein kinase [Streptococcus pneumoniae TIGR4] NP_346168 [Streptococcus pneumoniae TIGR4]
H.sapiens 2-280 -63.900 20  sp|Q9BXM7|PINK1_HUMAN Serine/threonine-protein kinase PINK1, mitochondrial OS=Homo sapiens GN=PINK1 PE=1 SV=1
36-294 -71.700 15  sp|Q9BXU1|STK31_HUMAN Serine/threonine-protein kinase 31 OS=Homo sapiens GN=STK31 PE=2 SV=2 (Range: 751-1019)
136-426 -53.700 14  sp|Q96GX5|MASTL_HUMAN Microtubule-associated serine/threonine-protein kinase-like OS=Homo sapiens GN=MASTL PE=1 SV=1 (Range: 151-450)
HGM_OVER 12-266 -3.950 PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;
NEW_HUMAN_DOMAINS 138-200 -4.550 20  sp|Q8TD84|DSCL1_HUMAN Down syndrome cell adhesion molecule-like protein 1 OS=Homo sapiens GN=DSCAML1 PE=1 SV=2 (Range: 1655-1722)
PDB1018 1-336 -110.000 100  4x3f_A mol:protein length:337 Serine/threonine-protein kinase PknA
2-384 -81.300 20  2pzi_A mol:protein length:681 Probable serine/threonine-protein kinase pknG
PfamA32U 12-260 -50.600 18  PF14531.6; B9QMZ2_TOXGV/253-542; Kinase-like
SCOP207 4-288 -102.000 40  d3orka1 d.144.1.7 (A:1-290) automated matches {Mycobacterium tuberculosis [TaxId: 419947]}
VFDB 4-343 -102.000 29  [RTKL] COG0515 Serine/threonine protein kinase
10-431 -48.300 19  [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase (MAP4K), germinal center kinase family
16 gi|15607158|ref|NP_214530.1|(removed signalp:1-30) penicillin-binding protein PbpA (Rv0016c) [Mycobacterium tuberculosis H37Rv] 461 COG1018 12-461 -94.700 24  [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
CSGID 12-458 -101.000 23  IDP00345 hypothetical protein lmo0441 lmo0441 [Listeria monocytogenes EGD-e]
H.sapiens 93-451 -5.340 12  sp|Q9UHX1|PUF60_HUMAN Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens GN=PUF60 PE=1 SV=1
HGM_OVER 43-193 -6.730 10  PB007733 A3U921_9FLAO/1-209 PB007733; Pfam-B_7733;
NEW_HUMAN_DOMAINS 100-189 -5.800 15  sp|Q9BVV6|K0586_HUMAN Uncharacterized protein KIAA0586 OS=Homo sapiens GN=KIAA0586 PE=1 SV=4 (Range: 833-942)
PDB1018 1-461 -136.000 99  3lo7_A mol:protein length:483 Penicillin-binding protein A
PfamA32U 12-93 -19.300 15  PF03717.15; Q31F48_HYDCU/68-242; Penicillin-binding Protein dimerisation domain
130-454 -74.000 21  PF00905.22; YQGFA_BACSU/352-682; Penicillin binding protein transpeptidase domain
SCOP207 12-107 -20.200 13  d1vqqa2 d.175.1.1 (A:139-327) Penicillin binding protein 2a (PBP2A), middle domain {Staphylococcus aureus [TaxId: 1280]}
108-460 -89.200 19  d1vqqa3 e.3.1.1 (A:328-668) Penicillin binding protein 2a (PBP2A), C-terminal domain {Staphylococcus aureus [TaxId: 1280]}
VFDB 12-461 -94.700 24  [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2
17 gi|15607159|ref|NP_214531.1|(removed signalp:1-35) cell division protein RodA (Rv0017c) [Mycobacterium tuberculosis H37Rv] 434 COG1018 1-420 -12.000 13  [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
35-415 -89.600 25  [D] COG0772 Bacterial cell division membrane protein
CSGID 12-414 -15.200 12  IDP91390 Lipid A core - O-antigen ligase [Vibrio vulnificus CMCP6] VV1_1426 [Vibrio vulnificus CMCP6]
H.sapiens 22-433 -8.330 12  sp|Q9Y267|S22AE_HUMAN Solute carrier family 22 member 14 OS=Homo sapiens GN=SLC22A14 PE=2 SV=4
HGM_OVER 293-433 -4.290 PB006154 _JGI.0331794_ 2004021056 [Human Gut Community Subject 7]
NEW_HUMAN_DOMAINS 253-318 -5.600 12  sp|O94761|RECQ4_HUMAN ATP-dependent DNA helicase Q4 OS=Homo sapiens GN=RECQL4 PE=1 SV=1 (Range: 1121-1208)
PDB1018 36-412 -90.100 28  6bar_A mol:protein length:359 Rod shape determining protein RodA
PfamA32U 45-410 -92.700 31  PF01098.19; SP5E_BACSU/10-366; Cell cycle protein
SCOP207 320-405 -6.400 15  d1oeda_ f.36.1.1 (A:) Acetylcholine receptor protein, alpha chain {Marbled electric ray (Torpedo marmorata) [TaxId: 7788]}
VFDB 1-420 -12.000 13  [M] COG3307 Lipid A core - O-antigen ligase and related enzymes
35-415 -89.600 25  [D] COG0772 Bacterial cell division membrane protein
18 gi|15607160|ref|NP_214532.1| serine/threonine phosphatase (Rv0018c) [Mycobacterium tuberculosis H37Rv] 514 COG1018 1-248 -67.200 29  [T] COG0631 Serine/threonine protein phosphatase
8-287 -28.700 16  [T] KOG0698 Serine/threonine protein phosphatase
CSGID 8-248 -82.000 34  IDP02614 hypothetical protein lmo1821 [Listeria monocytogenes EGD-e] lmo1821 [Listeria monocytogenes EGD-e]
12-419 -25.800 14  IDP92014 protein phosphatase 2C, putative [Toxoplasma gondii ME49] TGME49_067100 [Toxoplasma gondii ME49]
H.sapiens 8-279 -30.500 19  sp|P49593|PPM1F_HUMAN Protein phosphatase 1F OS=Homo sapiens GN=PPM1F PE=1 SV=3
9-242 -47.800 20  sp|Q8NI37|PPTC7_HUMAN(removed signalp:1-17) Protein phosphatase PTC7 homolog OS=Homo sapiens GN=PPTC7 PE=2 SV=1
418-506 -10.500 21  sp|Q99954|SMR3A_HUMAN(removed signalp:1-22) Submaxillary gland androgen-regulated protein 3A OS=Homo sapiens GN=SMR3A PE=2 SV=2
HGM_OVER 114-198 -3.830 20  PB044863 Q5LB69_BACFN/1-105 PB044863; Pfam-B_44863;
NEW_HUMAN_DOMAINS 428-506 -9.110 16  sp|Q9HAP2|MLXIP_HUMAN MLX-interacting protein OS=Homo sapiens GN=MLXIP PE=1 SV=2 (Range: 414-523)
PDB1018 4-240 -89.200 98  1txo_A mol:protein length:237 Putative Bacterial Enzyme
7-276 -30.200 14  3d8k_A mol:protein length:377 Protein phosphatase 2C
PfamA32U 30-231 -27.500 13  PF00481.21; B2AA70_PODAN/1451-1701; Protein phosphatase 2C
425-506 -10.800 17  PF12526.8; Q8JJN7_HEV/686-799; Protein of unknown function (DUF3729 topsan)
SCOP207 6-240 -88.800 98  d1txoa_ d.219.1.1 (A:) putative serine/threonine phosphatase pstp/ppp {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 1-248 -67.200 29  [T] COG0631 Serine/threonine protein phosphatase
8-287 -28.700 16  [T] KOG0698 Serine/threonine protein phosphatase
19 gi|15607161|ref|NP_214533.1| hypothetical protein (Rv0019c) [Mycobacterium tuberculosis H37Rv] 155 COG1018 42-155 -38.300 24  [T] COG1716 FOG: FHA domain
CSGID 63-154 -31.000 17  IDP92663 hypothetical protein BB0811 [Bordetella bronchiseptica RB50] NP_887360 [Bordetella bronchiseptica RB50]
H.sapiens 31-154 -38.700 13  sp|Q14676|MDC1_HUMAN Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens GN=MDC1 PE=1 SV=3 (Range: 1-300)
66-154 -44.700 21  sp|B1AJZ9|FHAD1_HUMAN Forkhead-associated domain-containing protein 1 OS=Homo sapiens GN=FHAD1 PE=2 SV=2 (Range: 1-300)
HGM_OVER 10-145 -5.290 10  HGC01213 gi|163579070|dbj|BABE01006032.1|2.0 TMP01709;
NEW_HUMAN_DOMAINS 95-151 -4.850 22  sp|O76015|KRT38_HUMAN Keratin, type I cuticular Ha8 OS=Homo sapiens GN=KRT38 PE=2 SV=3 (Range: 1-96)
PDB1018 49-154 -50.600 17  1r21_A mol:protein length:128 Antigen Ki-67
PfamA32U 65-155 -44.600 26  PF16697.5; E3FMY4_STIAD/31-122; Inner membrane component of T3SS, cytoplasmic domain
SCOP207 59-154 -48.900 22  d2ff4a3 b.26.1.2 (A:284-382) Probable regulatory protein EmbR, C-terminal domain {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 42-155 -38.300 24  [T] COG1716 FOG: FHA domain
20 gi|15607162|ref|NP_214534.1| hypothetical protein (Rv0020c) [Mycobacterium tuberculosis H37Rv] 527 COG1018 1-526 -9.770 [U] KOG1091 Ypt/Rab-specific GTPase-activating protein GYP6
23-435 -15.600 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
278-518 -24.100 12  [T] KOG3872 FOG: FHA domain
CSGID 32-520 -13.400 IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
443-526 -24.600 22  IDP92663 hypothetical protein BB0811 [Bordetella bronchiseptica RB50] NP_887360 [Bordetella bronchiseptica RB50]
H.sapiens 1-401 -10.700 15  sp|Q92734|TFG_HUMAN Protein TFG OS=Homo sapiens GN=TFG PE=1 SV=2
334-527 -18.900 15  sp|P85037|FOXK1_HUMAN Forkhead box protein K1 OS=Homo sapiens GN=FOXK1 PE=1 SV=1 (Range: 1-300)
430-525 -28.800 28  sp|P46013|KI67_HUMAN Antigen KI-67 OS=Homo sapiens GN=MKI67 PE=1 SV=2 (Range: 1-300)
HGM_OVER 2-144 -4.720 15  PB021133 Q64YN4_BACFR/1-310 PB021133; Pfam-B_21133;
NEW_HUMAN_DOMAINS 1-237 -4.930 13  sp|Q86XN7|PRSR1_HUMAN Proline and serine-rich protein 1 OS=Homo sapiens GN=PROSER1 PE=1 SV=2 (Range: 1-221)
PDB1018 1-132 -37.200 100  2lc0_A mol:protein length:132 Putative uncharacterized protein TB39.8
5-473 -16.700 5ife_C mol:protein length:1304 Splicing factor 3B subunit 1
374-525 -32.500 89  3oun_A mol:protein length:157 Putative uncharacterized protein TB39.8
PfamA32U 8-122 -32.800 28  PF12401.8; F8JSD1_STREN/4-118; Protein of unknown function (DUF2662 topsan)
442-527 -23.200 24  PF16697.5; E3FMY4_STIAD/31-122; Inner membrane component of T3SS, cytoplasmic domain
SCOP207 433-527 -26.300 100  d3po8a1 b.26.1.0 (A:3-97) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 1-526 -9.770 [U] KOG1091 Ypt/Rab-specific GTPase-activating protein GYP6
23-435 -15.600 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
278-518 -24.100 12  [T] KOG3872 FOG: FHA domain


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;