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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|6319249|ref|NP_009332.1|(removed signalp:1-20) hypothetical protein; Pau8p (YAL068C) [Saccharomyces cerevisiae] 100 COG1018 22-99 -5.990 15  [S] COG2431 Predicted membrane protein
CSGID 10-100 -6.790 7  IDP92617 hypothetical protein SAUSA300_1868 [Staphylococcus aureus subsp. aureus USA300_FPR3757] SAUSA300_1868 [Staphylococcus aureus subsp. aureus USA300_FPR3757]
H.sapiens 21-82 -7.570 22  sp|Q9H3S5|PIGM_HUMAN GPI mannosyltransferase 1 OS=Homo sapiens GN=PIGM PE=1 SV=1
HGM_OVER 24-94 -5.840 6  PB025553 _HOMD.0078651_ pint_c_1_4510 Prevotella intermedia 17 [1755134 - 1755736] ORF
NEW_HUMAN_DOMAINS 2-92 -7.460 16  sp|Q9UKL3|C8AP2_HUMAN CASP8-associated protein 2 OS=Homo sapiens GN=CASP8AP2 PE=1 SV=1
PDB1018 1-91 -8.490 12  2jk1_A mol:protein length:139 HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN HUPR1
PfamA32U 2-95 -43.900 23  PF00660.17; E7KHT3_YEASA/13-116; Seripauperin and TIP1 family
SCOP207 2-77 -8.620 11  d2bgga2 c.44.3.1 (A:11-170) Hypothetical protein AF1318 {Archaeoglobus fulgidus [TaxId: 2234]}
VFDB 22-99 -5.990 15  [S] COG2431 Predicted membrane protein
2 gi|33438754|ref|NP_878038.1| Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; Yal067w-ap (YAL067W-A) [Saccharomyces cerevisiae] 75 COG1018 3-73 -8.050 28  [S] COG4003 Uncharacterized protein conserved in archaea
CSGID 11-63 -5.030 22  IDP91344 hypothetical protein VV2_0026 [Vibrio vulnificus CMCP6] VV2_0026 [Vibrio vulnificus CMCP6]
H.sapiens 1-53 -9.200 20  sp|Q9P2D6|F135A_HUMAN Protein FAM135A OS=Homo sapiens GN=FAM135A PE=1 SV=2
HGM_OVER 3-64 -3.370 8  PB007011 gi|160888195|ref|ZP_02069198.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]gi|156862330|gb|EDO55761.1| hypothetical protein BACUNI_00603 [Bacteroides uniformis ATCC 8492]
NEW_HUMAN_DOMAINS 12-63 -6.840 17  sp|Q8N7L0|CM030_HUMAN Uncharacterized protein C13orf30 OS=Homo sapiens GN=C13orf30 PE=2 SV=1
PDB1018 13-74 -6.140 18  1udz_A mol:protein length:182 Isoleucyl-tRNA synthetase
PfamA32U 22-64 -6.960 32  PF05432.11; D2GX57_AILME/17-317; Bone sialoprotein II (BSP-II)
SCOP207 3-75 -6.430 8  d1yrba2 c.37.1.10 (A:1-245) ATP(GTP)-binding protein PAB0955 {Pyrococcus abyssi [TaxId: 29292]}
VFDB 3-73 -8.050 28  [S] COG4003 Uncharacterized protein conserved in archaea
3 gi|6319250|ref|NP_009333.1| Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide; Seo1p (YAL067C) [Saccharomyces cerevisiae] 593 COG1018 56-586 -98.200 13  [G] KOG2533 Permease of the major facilitator superfamily
CSGID 133-550 -44.600 14  IDP04335 putative transport protein [Salmonella typhimurium LT2] STM1543_1_428 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 3-286 -19.500 9  sp|Q496J9|SV2C_HUMAN Synaptic vesicle glycoprotein 2C OS=Homo sapiens GN=SV2C PE=2 SV=1
40-574 -41.600 8  sp|Q8IVW8|SPNS2_HUMAN Protein spinster homolog 2 OS=Homo sapiens GN=SPNS2 PE=1 SV=2
128-565 -44.900 8  sp|O43826|G6PT1_HUMAN Glucose-6-phosphate translocase OS=Homo sapiens GN=SLC37A4 PE=1 SV=1
HGM_OVER 220-356 -6.340 16  HGC00993 gi|163626727|dbj|BABG01009540.1|1.0 TMP01352;
NEW_HUMAN_DOMAINS 153-325 -5.820 11  tr|E9PPM1|E9PPM1_HUMAN Uncharacterized protein OS=Homo sapiens GN=TP53I11 PE=4 SV=1
PDB1018 107-583 -25.600 10  4j05_A mol:protein length:530 Phosphate transporter
121-566 -45.100 12  1pw4_A mol:protein length:451 Glycerol-3-phosphate transporter
PfamA32U 96-593 -19.700 9  PF06609.13; Q8NII4_FUSAU/1-598; Fungal trichothecene efflux pump (TRI12)
131-564 -20.800 11  PF00083.24; STP1_ARATH/26-489; Sugar (and other) transporter
146-548 -26.400 9  PF06779.14; Q8Y185_RALSO/36-399; Uncharacterised MFS-type transporter YbfB
SCOP207 124-564 -44.200 12  d1pw4a1 f.38.1.1 (A:5-448) Glycerol-3-phosphate transporter {Escherichia coli [TaxId: 562]}
VFDB 56-586 -98.200 13  [G] KOG2533 Permease of the major facilitator superfamily
4 gi|6319252|ref|NP_009335.1| Putative protein of unknown function; has homology to FLO1; possible pseudogene; (YAL065C) [Saccharomyces cerevisiae] 128 COG1018 79-128 -6.530 22  [T] KOG3797 Peripheral-type benzodiazepine receptor and related proteins
CSGID 3-104 -6.390 9  IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
H.sapiens 61-124 -7.650 23  sp|Q8TEW0|PARD3_HUMAN Partitioning defective 3 homolog OS=Homo sapiens GN=PARD3 PE=1 SV=2
HGM_OVER 99-127 -3.640 14  HGC00690 gi|162868815|dbj|BABB01001192.1|3.0 TMP00870;
NEW_HUMAN_DOMAINS 79-111 -6.340 27  sp|Q2KHR3|QSER1_HUMAN Glutamine and serine-rich protein 1 OS=Homo sapiens GN=QSER1 PE=1 SV=3
PDB1018 55-118 -7.790 14  2dk8_A mol:protein length:81 DNA-directed RNA polymerase III 39 kDa polypeptide
PfamA32U 89-126 -6.990 36  PF07666.11; Q8EWG6_MYCPE/16-144; M penetrans paralogue family 26
SCOP207 65-118 -6.700 13  d2dk8a1 a.4.5.85 (A:8-75) DNA-directed RNA polymerase III subunit RPC6, RPO3F {Mouse (Mus musculus) [TaxId: 10090]}
VFDB 79-128 -6.530 22  [T] KOG3797 Peripheral-type benzodiazepine receptor and related proteins
5 gi|6319253|ref|NP_009336.1| Fungal-specific protein of unknown function; Yal064w-bp (YAL064W-B) [Saccharomyces cerevisiae] 126 COG1018 32-126 -7.770 16  [C] KOG4769 Cytochrome c oxidase, subunit I
CSGID 1-97 -6.200 20  CPX_91710_91752 Complex of NXF1_HUMAN with TIP_SHV2C [Undefined organism]
H.sapiens 1-92 -8.380 15  sp|Q9NRM1|ENAM_HUMAN(removed signalp:1-39) Enamelin OS=Homo sapiens GN=ENAM PE=2 SV=3
HGM_OVER 6-125 -4.050 10  PB006205 Q3F123_BACTI/1-181 PB006205; Pfam-B_6205;
NEW_HUMAN_DOMAINS 92-123 -5.960 18  sp|Q9UPA5|BSN_HUMAN Protein bassoon OS=Homo sapiens GN=BSN PE=1 SV=4
PDB1018 32-126 -6.980 20  1fft_A mol:protein length:663 UBIQUINOL OXIDASE
PfamA32U 13-78 -7.580 35  PF17608.2; Q74KI2_LACJO/1-124; Family of unknown function (DUF5504 topsan)
SCOP207 32-126 -6.750 17  d3s8ga_ f.24.1.1 (A:) Bacterial ba3 type cytochrome c oxidase subunit I {Thermus thermophilus [TaxId: 274]}
VFDB 32-126 -7.770 16  [C] KOG4769 Cytochrome c oxidase, subunit I
6 gi|7839146|ref|NP_058136.1| Putative protein of unknown function; YAL064C-A is not an essential gene; Yal064c-ap (YAL064C-A) [Saccharomyces cerevisiae] 126 COG1018 9-116 -8.760 12  [S] COG4402 Uncharacterized protein conserved in bacteria
CSGID 2-113 -25.000 17  IDP92660 hypothetical protein CPE2277 [Clostridium perfringens str. 13] NP_563193 [Clostridium perfringens str. 13]
H.sapiens 1-126 -39.100 11  sp|P08F94|PKHD1_HUMAN(removed signalp:1-23) Fibrocystin OS=Homo sapiens GN=PKHD1 PE=1 SV=1
HGM_OVER 12-109 -5.920 15  PB011023 A7V2G7_BACUN/1-167 PB011023; Pfam-B_11023;
NEW_HUMAN_DOMAINS 2-111 -8.720 10  sp|A4D0S4|LAMB4_HUMAN Laminin subunit beta-4 OS=Homo sapiens GN=LAMB4 PE=2 SV=1
PDB1018 1-126 -55.300 70  4gq7_A mol:protein length:224 Flocculin
PfamA32U 1-98 -44.300 30  PF10528.9; B4UN21_CANGA/106-200; GLEYA domain
SCOP207 1-124 -53.800 80  d2xjpa1 b.179.1.2 (A:23-271) GLEYA domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
VFDB 9-116 -8.760 12  [S] COG4402 Uncharacterized protein conserved in bacteria
7 gi|6319254|ref|NP_009337.1| Protein of unknown function; may interact with ribosomes, based on co-purification experiments; (YAL064W) [Saccharomyces cerevisiae] 108 COG1018 18-95 -5.570 21  [S] KOG4487 Uncharacterized conserved protein
CSGID 49-81 -6.090 26  IDP92577 serine proteinase inhibitor TgPI-2, putative [Toxoplasma gondii ME49] TGME49_008430 [Toxoplasma gondii ME49]
H.sapiens 28-80 -7.590 26  sp|Q96PS6|GAFA1_HUMAN Putative uncharacterized protein GAFA-1 OS=Homo sapiens GN=GAFA1 PE=2 SV=1
HGM_OVER 15-103 -4.900 15  PB001934 Q6PSL5_CHLRE/821-1150 PB001934; Pfam-B_1934;
NEW_HUMAN_DOMAINS 9-96 -5.850 21  sp|Q9Y597|KCTD3_HUMAN BTB/POZ domain-containing protein KCTD3 OS=Homo sapiens GN=KCTD3 PE=1 SV=2
PDB1018 1-101 -6.700 13  5lfp_A mol:protein length:131 Bacterial proteasome activator
PfamA32U 15-82 -6.810 16  PF01822.19; A7ERH4_SCLS1/37-114; WSC domain
SCOP207 49-94 -7.250 23  d1nuba3 g.68.1.1 (A:78-135) Domain of BM-40/SPARC/osteonectin {Human (Homo sapiens) [TaxId: 9606]}
VFDB 18-95 -5.570 21  [S] KOG4487 Uncharacterized conserved protein
8 gi|33438755|ref|NP_878039.1| Putative protein of unknown function; identified by expression profiling and mass spectrometry; Yal063c-ap (YAL063C-A) [Saccharomyces cerevisiae] 96 COG1018 4-90 -6.220 11  [K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)
CSGID 13-73 -5.510 9  IDP00530 gene: ccmC; putative heme exporter protein C YPO2736 [Yersinia pestis CO92]
H.sapiens 26-95 -6.940 21  sp|Q6F5E8|LR16C_HUMAN Leucine-rich repeat-containing protein 16C OS=Homo sapiens GN=RLTPR PE=1 SV=2
HGM_OVER 7-83 -5.270 16  PB002776 gi|157737147|ref|YP_001489830.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]gi|157699001|gb|ABV67161.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]
NEW_HUMAN_DOMAINS 28-95 -7.960 16  sp|Q9Y2B1|TMEM5_HUMAN Transmembrane protein 5 OS=Homo sapiens GN=TMEM5 PE=2 SV=1
PDB1018 16-92 -7.090 10  1c0f_S mol:protein length:127 GELSOLIN SEGMENT 1
PfamA32U 31-94 -6.790 25  PF13798.6; X2GN24_9BACI/8-168; Protein of unknown function with PCYCGC motif
SCOP207 16-92 -6.820 10  d4cbug_ d.109.1.1 (G:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
VFDB 4-90 -6.220 11  [K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)
9 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 COG1018 146-499 -20.300 10  [TU] KOG3895 Synaptic vesicle protein Synapsin
228-499 -21.400 6  [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
CSGID 153-500 -21.400 6  IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
H.sapiens 110-337 -10.700 9  sp|P08F94|PKHD1_HUMAN(removed signalp:1-23) Fibrocystin OS=Homo sapiens GN=PKHD1 PE=1 SV=1
240-499 -16.200 10  sp|P16150|LEUK_HUMAN(removed signalp:1-19) Leukosialin OS=Homo sapiens GN=SPN PE=1 SV=1
312-499 -17.700 13  sp|P56975|NRG3_HUMAN Pro-neuregulin-3, membrane-bound isoform OS=Homo sapiens GN=NRG3 PE=1 SV=1
344-499 -17.900 12  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
HGM_OVER 4-20 -4.060 23  HGC01215 gi|162843249|dbj|BABA01001460.1|3.0 TMP01713;
NEW_HUMAN_DOMAINS 111-500 -8.180 8  sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2
PDB1018 1-254 -42.400 85  4lhl_A mol:protein length:263 Flocculation protein FLO1
110-499 -15.500 10  5ife_C mol:protein length:1304 Splicing factor 3B subunit 1
PfamA32U 4-216 -9.730 11  PF07691.12; Q7SG54_NEUCR/449-597; PA14 domain
112-213 -24.800 34  PF10528.9; B4UN21_CANGA/106-200; GLEYA domain
242-500 -13.900 4  PF08549.10; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)
SCOP207 1-245 -44.400 89  d2xjpa1 b.179.1.2 (A:23-271) GLEYA domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
VFDB 146-499 -20.300 10  [TU] KOG3895 Synaptic vesicle protein Synapsin
228-499 -21.400 6  [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
10 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 COG1018 1-485 -23.100 8  [TU] KOG3895 Synaptic vesicle protein Synapsin
CSGID 1-500 -31.600 7  IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
H.sapiens 1-161 -15.100 9  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
185-500 -19.700 7  sp|Q92804|RBP56_HUMAN TATA-binding protein-associated factor 2N OS=Homo sapiens GN=TAF15 PE=1 SV=1
HGM_OVER 417-494 -1.010 12  PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
NEW_HUMAN_DOMAINS 48-489 -2.470 6  sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2
PDB1018 40-491 -11.100 9  6fhj_A mol:protein length:1009 protein,protein
103-500 -18.700 8  5ife_C mol:protein length:1304 Splicing factor 3B subunit 1
PfamA32U 1-500 -11.800 11  PF06070.11; PP150_HCMVM/1-1048; Herpesvirus large structural phosphoprotein UL32
114-500 -13.300 7  PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
SCOP207 1-96 -2.920 7  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 1-485 -23.100 8  [TU] KOG3895 Synaptic vesicle protein Synapsin
11 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 COG1018 1-462 -23.700 9  [TU] KOG3895 Synaptic vesicle protein Synapsin
212-500 -21.200 6  [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
CSGID 1-500 -31.000 8  IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
H.sapiens 1-161 -15.900 13  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
17-273 -11.900 8  sp|O15240|VGF_HUMAN(removed signalp:1-22) Neurosecretory protein VGF OS=Homo sapiens GN=VGF PE=1 SV=2
211-500 -19.200 4  sp|Q92804|RBP56_HUMAN TATA-binding protein-associated factor 2N OS=Homo sapiens GN=TAF15 PE=1 SV=1
HGM_OVER 1-80 -1.530 13  PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
NEW_HUMAN_DOMAINS 33-500 -2.240 5  sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2
PDB1018 30-241 -10.700 11  5fur_J mol:protein length:677 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6
77-500 -18.200 7  5ife_C mol:protein length:1304 Splicing factor 3B subunit 1
PfamA32U 1-500 -11.600 12  PF06070.11; PP150_HCMVM/1-1048; Herpesvirus large structural phosphoprotein UL32
61-496 -13.200 12  PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
SCOP207 1-97 -2.610 13  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 1-462 -23.700 9  [TU] KOG3895 Synaptic vesicle protein Synapsin
212-500 -21.200 6  [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
12 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 500 COG1018 1-500 -24.300 10  [TU] KOG3895 Synaptic vesicle protein Synapsin
CSGID 2-500 -34.200 6  IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
H.sapiens 1-173 -21.400 6  sp|Q92804|RBP56_HUMAN TATA-binding protein-associated factor 2N OS=Homo sapiens GN=TAF15 PE=1 SV=1
211-500 -13.100 8  sp|O15240|VGF_HUMAN(removed signalp:1-22) Neurosecretory protein VGF OS=Homo sapiens GN=VGF PE=1 SV=2
363-500 -15.100 6  sp|O00555|CAC1A_HUMAN Voltage-dependent P/Q-type calcium channel subunit alpha-1A OS=Homo sapiens GN=CACNA1A PE=1 SV=2
HGM_OVER 66-147 -1.800 8  PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
NEW_HUMAN_DOMAINS 496-500 -1.180 0  sp|P52272|HNRPM_HUMAN Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens GN=HNRNPM PE=1 SV=3
PDB1018 1-415 -19.300 7  5ife_C mol:protein length:1304 Splicing factor 3B subunit 1
412-500 -13.100 10  6fhs_H mol:protein length:491 les2
PfamA32U 1-453 -13.200 9  PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
412-500 -12.100 6  PF05466.12; F6R3X8_HORSE/2-233; Brain acid soluble protein 1 (BASP1 protein)
SCOP207 1-116 -3.040 10  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 1-500 -24.300 10  [TU] KOG3895 Synaptic vesicle protein Synapsin
13 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] 298 COG1018 2-284 -25.600 7  [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
CSGID 2-288 -25.500 8  IDP91521 C2 domain-containing protein [Toxoplasma gondii ME49] TGME49_040910 [Toxoplasma gondii ME49]
H.sapiens 1-288 -22.100 9  sp|Q92804|RBP56_HUMAN TATA-binding protein-associated factor 2N OS=Homo sapiens GN=TAF15 PE=1 SV=1
HGM_OVER 209-298 -2.830 10  PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
NEW_HUMAN_DOMAINS 1-3 -2.530 0  sp|O43734|CIKS_HUMAN Adapter protein CIKS OS=Homo sapiens GN=TRAF3IP2 PE=2 SV=3
PDB1018 1-287 -19.900 8  5ife_C mol:protein length:1304 Splicing factor 3B subunit 1
PfamA32U 19-284 -15.600 9  PF17076.5; SBE22_CANGA/1-813; SBE2, cell-wall formation
SCOP207 5-121 -3.280 11  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 2-284 -25.600 7  [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
14 gi|6319256|ref|NP_009339.1| NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; Gdh3p (YAL062W) [Saccharomyces cerevisiae] 457 COG1018 1-455 -109.000 27  [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
CSGID 2-456 -110.000 28  IDP02649 putative glutamic dehyrogenase-like protein [Salmonella typhimurium LT2] STM1795 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 2-457 -95.600 23  sp|P49448|DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial OS=Homo sapiens GN=GLUD2 PE=1 SV=2
HGM_OVER 310-421 -2.770 10  PB022697 Q5LAY4_BACFN/1-165 PB022697; Pfam-B_22697;
NEW_HUMAN_DOMAINS 312-421 -4.980 11  sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-terminal hydrolase 35 OS=Homo sapiens GN=USP35 PE=1 SV=3
PDB1018 2-456 -116.000 49  3r3j_A mol:protein length:456 Glutamate dehydrogenase
PfamA32U 3-454 -22.600 13  PF05088.12; A4XWG7_PSEMY/77-1608; Bacterial NAD-glutamate dehydrogenase
40-168 -73.700 31  PF02812.18; R6WCN3_9CLOT/34-162; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
185-454 -72.400 32  PF00208.21; DHE3_ORYSJ/176-408; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
SCOP207 9-184 -76.000 31  d1gtma2 c.58.1.1 (A:3-180) Glutamate dehydrogenase {Pyrococcus furiosus [TaxId: 2261]}
180-457 -76.900 40  d1bgva1 c.2.1.7 (A:195-449) Glutamate dehydrogenase {Clostridium symbiosum [TaxId: 1512]}
VFDB 1-455 -109.000 27  [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
15 gi|6319257|ref|NP_009340.1| Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene; Bdh2p (YAL061W) [Saccharomyces cerevisiae] 417 COG1018 1-382 -85.600 29  [Q] KOG0024 Sorbitol dehydrogenase
89-417 -10.700 12  [J] KOG2915 tRNA(1-methyladenosine) methyltransferase, subunit GCD14
CSGID 1-376 -78.800 25  IDP02503 gene: gutB; putative zinc-binding dehydrogenase [Yersinia pestis CO92] YPO2502 [Yersinia pestis CO92]
7-417 -10.300 12  IDP90674 gene: hemA; glutamyl-tRNA reductase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0542 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
H.sapiens 1-382 -85.200 29  sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo sapiens GN=SORD PE=1 SV=4
89-417 -10.800 12  sp|Q9BVS5|TR61B_HUMAN(removed signalp:1-20) Potential tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B OS=Homo sapiens GN=TRMT61B PE=1 SV=2
HGM_OVER 12-137 -4.890 13  HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
NEW_HUMAN_DOMAINS 34-131 -5.680 20  sp|O75592|MYCB2_HUMAN Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 PE=1 SV=3
PDB1018 1-378 -90.400 29  5vm2_A mol:protein length:347 Alcohol dehydrogenase
PfamA32U 26-159 -44.900 35  PF08240.12; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain
144-417 -10.300 11  PF08704.10; Q6DFS3_XENTR/64-300; tRNA methyltransferase complex GCD14 subunit
167-387 -40.800 18  PF16912.5; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus
SCOP207 1-203 -69.100 29  d1pl8a1 b.35.1.2 (A:1-145,A:317-356) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
87-417 -10.300 11  d2b25a1 c.66.1.13 (A:6-329) Hypothetical protein FLJ20628 {Human (Homo sapiens) [TaxId: 9606]}
164-337 -49.600 28  d1pl8a2 c.2.1.1 (A:146-316) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-382 -85.600 29  [Q] KOG0024 Sorbitol dehydrogenase
89-417 -10.700 12  [J] KOG2915 tRNA(1-methyladenosine) methyltransferase, subunit GCD14
16 gi|6319258|ref|NP_009341.1| NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source; Bdh1p (YAL060W) [Saccharomyces cerevisiae] 382 COG1018 1-381 -86.000 25  [Q] KOG0024 Sorbitol dehydrogenase
CSGID 1-382 -78.500 23  IDP00931 gene: ybdR; putative dehydrogenase STM0615 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
H.sapiens 1-381 -85.600 25  sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo sapiens GN=SORD PE=1 SV=4
HGM_OVER 12-137 -5.120 9  HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
NEW_HUMAN_DOMAINS 34-131 -5.550 23  sp|O75592|MYCB2_HUMAN Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 PE=1 SV=3
PDB1018 1-377 -89.600 25  5vm2_A mol:protein length:347 Alcohol dehydrogenase
PfamA32U 26-159 -46.200 32  PF08240.12; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain
167-382 -42.000 19  PF16912.5; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus
SCOP207 1-203 -68.700 25  d1pl8a1 b.35.1.2 (A:1-145,A:317-356) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
164-336 -49.200 24  d1pl8a2 c.2.1.1 (A:146-316) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-381 -86.000 25  [Q] KOG0024 Sorbitol dehydrogenase
17 gi|6319259|ref|NP_009342.1| Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export; Ecm1p (YAL059W) [Saccharomyces cerevisiae] 212 COG1018 3-64 -7.050 14  [S] KOG2890 Predicted membrane protein
CSGID 1-172 -7.730 11  IDP05117 putative collagen-binding protein [Clostridium difficile 630] CD2831 [Peptoclostridium difficile 630]
H.sapiens 1-152 -7.760 10  sp|O95886|DLGP3_HUMAN Disks large-associated protein 3 OS=Homo sapiens GN=DLGAP3 PE=1 SV=3
HGM_OVER 71-135 -4.440 9  PB003142 Q8DVS6_STRMU/1-162 PB003142; Pfam-B_3142;
NEW_HUMAN_DOMAINS 2-53 -5.290 13  sp|Q76FK4|NOL8_HUMAN Nucleolar protein 8 OS=Homo sapiens GN=NOL8 PE=1 SV=1
PDB1018 1-169 -7.040 9  6b5v_A mol:protein length:730 Transient receptor potential cation channel subfamily V member 5
PfamA32U 31-152 -61.400 52  PF09135.11; Q6CLT8_KLULA/8-125; Alb1
SCOP207 1-49 -6.070 16  d4i43b3 c.52.1.36 (B:1653-1838) Pre-mRNA splicing factor 8, Prp8 / Spp42 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
VFDB 3-64 -7.050 14  [S] KOG2890 Predicted membrane protein
18 gi|6319260|ref|NP_009343.1|(removed signalp:1-19) Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast; Cne1p (YAL058W) [Saccharomyces cerevisiae] 483 COG1018 1-435 -113.000 29  [O] KOG0675 Calnexin
CSGID 1-117 -6.100 12  IDP91976 hypothetical protein HMPREF0837_10616 [Streptococcus pneumoniae TCH8431/19A] HMPREF0837_10616 [Streptococcus pneumoniae TCH8431/19A]
H.sapiens 1-434 -122.000 30  sp|P27824|CALX_HUMAN(removed signalp:1-20) Calnexin OS=Homo sapiens GN=CANX PE=1 SV=2
HGM_OVER 34-141 -4.140 7  PB042013 A7V626_BACUN/1-162 PB042013; Pfam-B_42013;
NEW_HUMAN_DOMAINS 304-406 -5.670 15  sp|Q99932|SPAG8_HUMAN Sperm-associated antigen 8 OS=Homo sapiens GN=SPAG8 PE=1 SV=2
PDB1018 1-421 -135.000 31  1jhn_A mol:protein length:424 calnexin
PfamA32U 14-394 -125.000 32  PF00262.18; R4XC34_TAPDE/40-408; Calreticulin family
SCOP207 3-261 -69.800 23  d1jhna4 b.29.1.12 (A:61-262,A:412-458) Calnexin {Dog (Canis familiaris) [TaxId: 9615]}
222-363 -54.400 44  d1jhna3 b.104.1.1 (A:270-411) Calnexin {Dog (Canis familiaris) [TaxId: 9615]}
VFDB 1-435 -113.000 29  [O] KOG0675 Calnexin
19 gi|41629666|ref|NP_009345.2| Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p; Gpb2p (YAL056W) [Saccharomyces cerevisiae] 880 COG1018 4-864 -23.700 9  [TR] KOG4441 Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
173-866 -43.100 10  [T] KOG2437 Muskelin
265-866 -46.800 13  [R] KOG1230 Protein containing repeated kelch motifs
CSGID 16-875 -21.400 11  IDP90191 gene: CPXV193 CDS; CPXV193 protein AAM13632.1 [Cowpox virus (Brighton Red)]
283-870 -27.000 12  IDP04233 putative lipoprotein [Clostridium perfringens ATCC 13124] CPF_0722 [Clostridium perfringens ATCC 13124]
H.sapiens 3-850 -22.900 11  sp|Q2WGJ6|KLH38_HUMAN Kelch-like protein 38 OS=Homo sapiens GN=KLHL38 PE=2 SV=3
272-867 -47.300 11  sp|Q8TBB5|KLDC4_HUMAN Kelch domain-containing protein 4 OS=Homo sapiens GN=KLHDC4 PE=1 SV=1
HGM_OVER 1-191 -3.960 11  HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;
NEW_HUMAN_DOMAINS 2-105 -6.890 11  sp|Q5TG08|YV009_HUMAN Putative uncharacterized protein LOC388900 OS=Homo sapiens PE=1 SV=2
PDB1018 4-880 -21.800 12  2zw9_A mol:protein length:695 Leucine carboxyl methyltransferase 2
276-871 -43.900 11  5gqt_A mol:protein length:478 Nitrile-specifier protein 1
PfamA32U 258-851 -34.400 11  PF03089.14; F6YI02_MONDO/51-390; Recombination activating protein 2
SCOP207 287-804 -20.200 12  d3ii7a_ b.68.11.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
498-880 -19.600 12  d2vpja_ b.68.11.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
VFDB 4-864 -23.700 9  [TR] KOG4441 Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
173-866 -43.100 10  [T] KOG2437 Muskelin
265-866 -46.800 13  [R] KOG1230 Protein containing repeated kelch motifs
20 gi|6319263|ref|NP_009346.1| Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation; Pex22p (YAL055W) [Saccharomyces cerevisiae] 180 COG1018 4-143 -6.650 8  [S] COG5353 Uncharacterized protein conserved in bacteria
CSGID 36-161 -6.080 10  IDP06515 protein of hypothetical function DUF552 [Enterococcus faecium DO] AFK58423 [Enterococcus faecium DO]
H.sapiens 5-155 -6.850 9  sp|Q6ZPD9|D19L3_HUMAN Protein dpy-19 homolog 3 OS=Homo sapiens GN=DPY19L3 PE=2 SV=1
HGM_OVER 64-167 -4.740 7  PB044822 Q89ZL7_BACTN/1-147 PB044822; Pfam-B_44822;
NEW_HUMAN_DOMAINS 86-166 -6.900 8  tr|B1AHL2|B1AHL2_HUMAN Fibulin 1 OS=Homo sapiens GN=FBLN1 PE=4 SV=1
PDB1018 51-180 -74.100 97  2y9m_B mol:protein length:130 PEROXISOME ASSEMBLY PROTEIN 22
PfamA32U 51-167 -55.300 22  PF12827.7; C4Y073_CLAL4/43-162; Peroxisomal biogenesis protein family
SCOP207 44-155 -8.100 13  d1x4fa1 d.58.7.1 (A:8-106) Matrin 3 {Mouse (Mus musculus) [TaxId: 10090]}
VFDB 4-143 -6.650 8  [S] COG5353 Uncharacterized protein conserved in bacteria

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Rychlewski L, Li Z, Li W, Godzik A. FFAS03: a server for profile--profile sequence alignments. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W284-8.