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Query: gi|11497095|ref|NP_051172.1| hypothetical protein (BB_P11) [Borrelia burgdorferi B31], from B.burgdorferi

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPQDTISVSLLDSRIQASRPNYYNPLLVYKTAKIKVNKDAASYKILNLTVNNYEKQIETLEKENGNGEDQFGKEKTLLKTAMSNFFNSSEESLKSADLFIYKDKPEELKNYLKVHRHTFVVLINTEGDASDDGLKIYKDDYNKFKKPSTFFVFSTKEQEIKELFKDKGNTEKERNIAVYSNNKDNLHLKFISQYLHQASIFHAVNPYGMPLAATPLVDDTVIGKLRTAKINFYSLLNETGLDGVPAFKEGVDLAGGAIDEQFTYHYIKNEAIIELIRIWNKNNRQNSKLSALQLSGARDNAYTSAIECLLKRFVDRGLIIEYKNLRLTLSPTPQLKLELSVNITYNFSINAVALVITTQDIVDYQNSLSALast
1 -5.950[O] COG3175 Cytochrome oxidase assembly factor  ali follow..  12  33..........................................................................................................................................................................................................VVMMFGFGYAMVPLYK---------------KICELTNINVLTTFDSNSQGPFRFRPVKNSMEVHPGEINQIVYEVVNKEGRSVSAQAIPSYAPKQATEFFKKIECFC-----------FKQQTLAGNESREMPVVFVIDPDLPKDVKTITLSYTFFEIGKPVAQTPT 196
2 -5.920[T] COG5040 14-3-3 family protein  ali follow..  16  5....................................REDSVYLAKLAEQAERYEEMVENMKTVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELICSYRSKIETE-KISDDILSVLDS-----------HLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNASLEAYKTAS--------IATTELPPTHPIRLGLALNFSVFYYEIQNSP-DKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRLWTSDMSESGQ.................................................................................. 242
3 -5.050[R] KOG4733 FOG: RRM domain  ali follow..  13  3..................................KVWKQQMYPQYATYYYPQYLQAKQSLVPAHPMAPPSPSTTSSNNNSSSSS--NSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVS---------TKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSS-----TSRGVGFARMESTEKCEAVIGHFNGKFIKTPPG................................................................................................................ 211
4 -4.870[O] KOG0841 Multifunctional chaperone (14-3-3 family)  ali follow..  15  3....................................KNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIE--TELRDICNDVLSLLEK-----------FLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAF--------ISKKEMQPTHPIRLGLALNFSVFYYEILNSP-EKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRLWTSDTQGDEAEAGEGGEN.......................................................................... 245
5 -4.470[Z] KOG3155 Actin-related protein Arp2/3 complex, subunit ARPC3  ali follow..  16  32.PTVDIPNDIIDESLYFWKSNIF-----FRTYEVKSEVD----RVLIYITLYITECLKRLARCTSKSQG----QQELYTLAISRFDIPGDAGFPLNGIYTKPEDPELMRQYFLQLRQETGNRLLEKVFDTPDG------------KPSKWWICFAKKKFMEKSLSGPG.......................................................................................................................................................................................................... 173
6 -3.890[S] COG4866 Uncharacterized conserved protein  ali follow..  14  118...........................VYSIEELQFLTNHANFVYEKISPQNKKEVLEASQAESQTDDIGLINENKGIQSVLENYESLDVKGGEIASFSFIAGAYQIINQQLLLNEFSHLTYANREEDLGLEGLRRSKMSYNPVFLIDKYEA.......................................................................................................................................................................................................................... 286
7 -3.840[S] KOG3236 Predicted membrane protein  ali follow..  20  2......................................................................................................................................................................................................TLFHFFNPHAVYYSATPLSEYDTLGTSVKAAVVYLTFLQVSETEVFDPYQEALKAMIGFIDVAGLYYALAQLT--------HRNISQNHKFQAVGLGWAFADSVLHRLAPLW--VGARGLEFTWDYVLQGLEANANLVFTISLAA........................... 154
8 -3.820[S] COG3826 Uncharacterized protein conserved in bacteria  ali follow..  10  166.....................................................................................................................QVAILLSEPGADFTGGEFVMTEQRPRMQSRPDVV------------------PLRKGDAAVFAVSQRPVQ----ARGPYRVTMRHGVSRLGQRHTVGIIFHDAL..................................................................................................................................................... 250
9 -3.790[M] COG5632 N-acetylmuramoyl-L-alanine amidase  ali follow..  10  1...............................................................................................................MKKLVKSAVVFASLALIGTSATLITEKASASSIE--------TVQKVDDQSIYIPQGIRDGTATEEHDGFEDETNSVLKTTSLLRATTGYPDVNAY---IKSNKFSTASIEKQLKSQFPKFGVVIHETANNSSTIEGE-ISYMSRNYNNAFVHSFVDKSRIIQIHGVWGAGQYANARFIQVELVRSKTRSINNYAYYAAYLLDQYKL.................................................... 214
10 -3.590[S] KOG1008 Uncharacterized conserved protein, contains WD40 repeats  ali follow..  12  483......................................................................................................NNSNKLICYRSEQRDLALQLCGWAFEQELDRFIDQLYANKEYSRAAMICVFHLKIFHACNILSSAADNMRDPSLSSFNADRCSSTWRNQRSSANM----QIHDPH------------AVFSFLTMEKDNFDAVLKEEGV----SLSDRMAFA---------CKYLSETKLADYVAQQIQAAIDGGDLNGLLLTGESQDGID-----ILQSYMDTSFDVQTVALVAINYFRQELFEDKRIQ-SYLDHLNSWGLWEKRAELDIKIESIRP 729

FFAS is supported by the NIH grant R01-GM087218-01
1 3 5 0 8 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.