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Query: gi|60682029|ref|YP_212173.1| putative bifunctional CbiF/CbiG cobalamin biosynthesis protein (BF2549) [Bacteroides fragilis NCTC 9343] (Range: 1-599), from B.fragilis

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKTAIIVISEAGIALAKTLEQELPESEIFSTGTDTDCHSISNLQEAVPEIFHKFDAIIFIGAMGICIRAIAPHIEDKHKDPAVVCVDSTGRYAVSVLSGHIGGANGLTRYVASILGAEPVITTRSDRTGLWALDTLGKKYGWQTVPAESSDMNHLITLFVDCKPTALLLDIRDEGTTQLEHTLPPHVDVFYKFEDMDLRKYDLLLLVTPFIYNTSDTPALYYVPPVLHMGVGLARDAHPVDTVITHLMDVVVQANMIPLAIRTVSSIEEKKDEPVLKLLAEAYQTRLYTASQLSKIEVPTPSEVVNKHMGTPSVSEASALLSSGGGPLLLPKQKGANFTVAIAMDAASVRQGHIEIVGAGPGDPELISVRGRHFLEEADLILYAGSLVPRELTECAKAGATIRSSASMTLEEQFALMKEFYDRGQLVVRLHTGDPCIYGAIQEQMNFFDQYGMHYHITPGISSFQAAAAALQSQFTIPERVQTIILTRGEGRTPMPEKEKLSLLARSQSTMCIFLSAGVVDQVQRELLEHYPPTTPVAACYHLTWKDERIFRGQLQDLAKIVNENHLTLTTMIVVGDAIDNREGLSRLYSHQFKHLFRKLast
1 -67.4004e16_A mol:protein length:253 precorrin-4 C(11)-methyltransferase  ali model follow..  44  3.............................................................................................................................................................................................................................................................................................................................................................AMNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLEYCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLNIDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTSMVIFLSVQEIEKVVSKLLEGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNINKTALIMVGRFLGEEYNNSKLYDKDFKHEYR. 252
2 -67.1003eeq_A mol:protein length:336 putative Cobalamin biosynthesis protein G homolog  ali model follow..  20  9RGICIISASEDAFSAGETIKEKLKSFEIPV-------VHYRYKDAEIETIWKCYDAIVFVMALEGATRIVCKYAKSKTEDPAIVCIDDKINYVIPLLGGH-WGANDIARELSVILNSTPIITTAAEIKGKLSIERIANILIAKII--NPENIVKINAALLRDESICIDGIDVNVNFPE---------------NIKVNSEECSYIISLRGDKEYKDKIVVWLKPLKISIGIGSKKDV-KMEEIRDGIYKVLERLNLKRERIGIIASI-----REEVKKIADEFNVRFVNEEEINNFMNPTPPSKTLIEVGLKGVAEISALIAGGNSKLILRKIAIRNSTIAVATYE............................................................................................................................................................................................................................................................. 329
3 -64.1003nei_A mol:protein length:281 Precorrin-4 C(11)-methyltransferase  ali model follow..  34  1.................................................................................................................................................................................................................................................................................................................................................MGSSSSGLVPRGSHMTVHFIGAGPGAADLITIRGRDLIASCPVCLYAGSLVPEALLAHCPPGAKIVNTAPMSLDAIIDTIAEAHAAGQDVARLHSGDLSIWSAMGEQLRRLRALNIPYDVTPGVPSFAAAAATLGAELTLPGVAQSVILTRTSGRSAMPAGETLENFARTGAVLAIHLSVHVLDEVVQKLVPHYGEDCPVAIVWRASWPDQRVVRATLATLQTSLG-AELERTALILVGRSLATEDFDESR........... 251
4 -62.5001cbf_A mol:protein length:285 COBALT-PRECORRIN-4 TRANSMETHYLASE  ali model follow..  41  1.................................................................................................................................................................................................................................................................................................................................................MGSSSSGLVPRGSHMKLYIIGAGPGDPDLITVKGLKLLQQADVVLYADSLVSQDLIAKSKPGAEVLKTAGMHLEEMVGTMLDRMREGKMVVRVHTGDPAMYGAIMEQMVLLKREGVDIEIVPGVTSVFAAAAAAEAELTIPDLTQTVILTRAEGRTPVPEFEKLTDLAKHKCTIALFLSSTLTKKVMKEFINGWSEDTPVVVVYKATWPDEKIVRTTVKDLDDAMRTNGIRKQAMILAGWALDPATP............... 248
5 -56.8002zvb_A mol:protein length:295 Precorrin-3 C17-methyltransferase  ali model follow..  21  2...............................................................................................................................................................................................................................................................................................................................................................GELFLVGMGPGDLPGLTQRAREALEGAEVVIGYSTYVKLLEEMGLLAGKEVVRKGMTEELDRAEEALERALSGQRVALVSGGDPGIYGMAAPVLELMEERGVFLAVIPGVTAANAVASLLGSPLAH----DTCLISLSDLLTPWPLIERLHAAGQGDFVVVLYNPQSKLRKSAEILLEYRPKETPAALVKSAYRKRQEVALTTLEGL----REAEAGMLTTVVIGNRQSRFYEGTFL-TPRGY..... 261
6 -55.6003nut_A mol:protein length:251 Precorrin-3 methylase  ali model follow..  21  2..............................................................................................................................................................................................................................................................................................................................................................SGWVTVAGLGPGREDLVTPEVTAALAEATDIVGYIPYVARI-----REGLTLHPTDNRVELDRATHALEMAAEGRRVVVVSSGDPGVFAMASALFEALEAHGTEIRILPGITAMLAAAAAAGAPLGH----DFCAINLSDNLKPFEILERLRHAARGDFAMAFYNPRSKFTRVLEILREECEPGRLILFARAVTTPEQAISVVELRDA----TPEMADMRTVVLVGNAATRRVG-PWVYTPRGV..... 243
7 -55.3002ybo_A mol:protein length:294 METHYLTRANSFERASE  ali model follow..  22  1.......................................................................................................................................................................................................................................................................................................................................AMADIGSMNTTVIPPSLLDVDFPAGSVALVGAGPGDPGLLTLRAWALLQQAEVVV-YDRLVARELIALLPESCQRIYVHSLPQEEINELLVRLARQQRRVVRLKGGDPFIFGRGAEELERLLEAGVDCQVVPGVTAASGCSTYAGIPLTHRDLAQSCTFVTGHLQNDGRLDLDWAGLARGKQTLVFYMGLGNLAEIAARLVEGLASDTPAALVSQGTQAGQQVTRGALAELPALARRYQLKPPTLIVVGQVVALFAERAMAHPS........ 270
8 -55.2002ybq_A mol:protein length:292 METHYLTRANSFERASE  ali model follow..  22  2..........................................................................................................................................................................................................................................................................................................................................PLGSMNTTVIPPSLLDVDFPAGSVALVGAGPGDPGLLTLRAWALLQQAEVVV-YDRLVARELIALLPESCQRIYVHSLPQEEINELLVRLARQQRRVVRLKGGDPFIFGRGAEELERLLEAGVDCQVVPGVTAASGCSTYAGIPLTHRDLAQSCTFVTGHLQNDGRLDLDWAGLARGKQTLVFYMGLGNLAEIAARLVEGLASDTPAALVSQGTQAGQQVTRGALAELPALARRYQLKPPTLIVVGQVVALFAERAMAHPS........ 268
9 -54.3001s4d_A mol:protein length:280 Uroporphyrin-III C-methyltransferase  ali model follow..  21  1.................................................................................................................................................................................................................................................................................................................................................MIDDLFAGLPALEKGSVWLVGAGPGDPGLLTLHAANALRQADVIV-HDALVNEDCLKLARPGAVLEFAPSPKQRDISLRLVELARAGNRVLRLKGGDPFVFGRGGEEALTLVEHQVPFRIVPGITAGIGGLAYAGIPVTHREVNHAVTFLTGHDSSG-PDRINWQGIASGSPVIVMYMAMKHIGAITANLIAGRSPDEPVAFVCNAATPQQAVLETTLARAEADVAAAGLEPPAIVVVGEVVRLRAALDWI........... 258
10 -53.4001ve2_A mol:protein length:235 Uroporphyrin-III C-methyltransferase  ali model follow..  23  1.............................................................................................................................................................................................................................................................................................................................................................MRGKVYLVGAGFGGPEHLTLKALRVLEVAEVVL-HDRLVHPGVLALAKGELKEGYGGKTPQEAITARLIALAREGRVVARLKGGDPMVFGRGGEEALALRRAGIPFEVVPGVTSAVGALSALGLPLTHRGLARSFAVATGH---------DPALPLPRADTLVLLMPLHTLGGLKERLLERFPPETPLALLARVGWPGEAVRLGRVEDLPGLGE--GLPSPALLVVGKVVGLYGELLPKDHG........ 234
11 -52.1001pjq_A mol:protein length:457 Siroheme synthase  ali model follow..  17  6...................................................................................IFCQLRDRDCL------VGGGDVAERKARLLLEAGARLT-------VNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRV-------------SDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSG-----GTSPVLARLLREKLES--LLPQHLGQVARY---------------------AGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHR-----GEVVLVGAGPGDAGLLTLKGLQQIQQADIVV-YDRLVSDDIMNLVRRDADRVFVHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGEL--DWENLAAEKQTLVFYMGLNQAATIQEKLIAGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQ--QVESPALIIVGRVVALRDKLNWFSN......... 456
12 -46.5001v9a_A mol:protein length:239 Uroporphyrin-III C-methyltransferase  ali model follow..  22  1...............................................................................................................................................................................................................................................................................................................................................................GRVYLVGAGPGDPELLTLKAYRLLKEAPVVL-YDRLVDERVLALAPGEKVYVGKESEKQEEIHRLLLRHARAHPFVVRLKGGDPMVFGRGGEEVLFLLRHGVPVEVVPGVTS----LLASGLPLTHRGLAHGFAAVSGVLEG--GGYPDLRPFARVP-TLVVLMGVGRRVWIAKELLRGRDPREPTLFVERASTPKERRVHARLEEVAEGK--VEVRPPALWILGEVVRVFAEKEAPVDAL....... 235
13 -43.7002e0k_A mol:protein length:259 Precorrin-2 C20-methyltransferase  ali model follow..  20  3.............................................................................................................................................................................................................................................................................................................................................................NQGSIISVSLGPGDPGLITVKALSQLREADVIYYVTSVALDILKEFDLDPSKLRGAAEASYAANYASMAEEVQAGRRVAVVSVGDGGFYSTASAIIERARRDGLDCSMTPGIPAFIAAGSAAGMPLALQS--DSVLVLAQI-----DEIGELERALVTHSTVVVMKLSTVRDELVSFLERY---AKPFLYAEKVGMAGEFITME-----VDALRSRAIPYFSLLVCSPHCRQSTLSPFA---SKLAAALE 253
14 -43.4002qbu_A mol:protein length:232 Precorrin-2 methyltransferase  ali model follow..  17  2..............................................................................................................................................................................................................................................................................................................................................................HGKLIGVGVGPGDSELLTLRAVNVLRSVPVICAPRSSIVEDILTERRDGCRILDELESHWDSAARMVAAELEDGRDVAFITLGDPSIYSTFSYLQQRIEDMGFKTEMVPGVTSFTACAATAGRTLVEGD--EILLVVPRV-------DDRFERVLRDVDACVIMKTSRHGRRAMEVVES-DPRGKDVVSVANCSMDDEVVERGFASGG---------GYLATTLVRF...................... 228
15 -40.8003i4t_A mol:protein length:292 diphthine synthase  ali model follow..  14  1.................................................................................................................................................................................................................................................................................................................................................MAMGTLEAQTQGPGSMLYIIGLGLYDEKDITVRGLEAVKSCDLVFLYTAILQCDVAKLEEFYGKKVIIGDRDLVETEADQILEPAKTKNVALLVVGDVYGATTHSDIFVRCQKMGIEVKVIHNASIMNAIGCSGLQLYRFNNMHTLVLLDIKVKERSEESIIKGRDIFEPPRYMTINQCIEQLLEVEKEQHLGYDEDTMVVGMARVACADQKIVYGKMKDLLH--YDFGAPMHCLLIPAPQVDDPEL............... 275
16 -39.9002npn_A mol:protein length:251 Putative cobalamin synthesis related protein  ali model follow..  15  3...............................................................................................................................................................................................................................................................................................................................................................RTIYVIGIGTGSPEFLTLQAISGLRHAQAIVALDK-LRQKIVDTHAPGTPIYRWHAERAHLLASTIRERTPDDGAVAFLVWGDPSLYDSTLEHMRNLEDLHADVKVIPGITAVQVLTAEHGILINRIG--EAIHITTGRNLPE-------TSAKDRRNCVVMLDGKTAWQDVAT-------EHTYMWWGAFLGTEQQVLRKGYVHEIGAQVA--ELKQQLRTEHGWIMDT.................. 244
17 -38.4003nd1_A mol:protein length:275 Precorrin-6A synthase/CobF protein  ali model follow..  13  3..................................................................................................................................................................................................................................................................................................................................................SSSSGLVPRGSHMIELSLIGIGTGNPRHITGQAVDAMNAADLILIPLKGADKSDLAGLRRKGVDDWHDAIAETWLSEITAHVPGLEGRVALLVWGDPSLYDSTLRIAERLKSRPLTTKVIPGITAIQALCAAHAIPLNDIG--APVVITTGRQLRD-------HGWPAGTETVVAMLDGECSFQSLP------PDGLTIFWGACVAMPEEVLIRGPVAEVTDEILQ--ARADLRARHGWVMDI.................. 259
18 -38.2001vce_A mol:protein length:265 diphthine synthase  ali model follow..  13  3.................................................................................................................................................................................................................................................................................................................................................................LYFIGLGLYDERDITVKGLEIAKKCDYVF-AEFYTSLMAGTTLGRIQKLIGKEIRVELNFENIVLPLA-KENDVAFLTPGDPLVATTHAELRIRAKRAGVESYVIHAPSIYSAVGI-TGLHIYKFGKSATVAYPEGNWFPGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGFTDDTLVVVLARAGSLNPTIRAGYVKDLIR--EDFGDPPHILIVPGKLHIVEAE............... 248
19 -37.1001vhv_A mol:protein length:268 diphthine synthase  ali model follow..  17  5.............................................................................................................................................................................................................................................................................................................................................................HMSLLTFVGLGLWDVKDISVKGLEAVREADEVY-VEYYTSKLLSSIEE-GKRVVELERSDLEENSFRLIERA-KSKSVVLLVPGDPMVATTHSAIKLEAERKGVKTRIIHGASISTAVCGLTGLHNYRFGKSATVSWHRSQTPVNVIKANRSIDAHTLLFLDLHPEPMTIGHAVENLIEDAQMKDLYAVGIARAGSGEEVVKCDRLENLKKI--DFGKPLHVMVVLAKTLHFMEF............... 240
20 -36.4001wde_A mol:protein length:294 Probable diphthine synthase  ali model follow..  14  7..............................................................................................................................................................................................................................................................................................................................................................AVTLLLVGWGYAP-GMQTLEALDAVRRADVVY-VESYTMPGSSWLYKSEARVVEASRRDLEERSREIVSRA-LDAVVAVVTAGDPMVATTHSSLAAEALEAGVAVRYIPGVSGVQAARGATMLSFYRFGGTVTLPGPWRGVTPISVARRIYLNLCAGLHTTALLQGVSLLLEADREYARELARLPSVLVEAGAGGGHRVLYWSSLERLSTA--DVEGGVYSIVIPARLSGVEEWLLAAASGQRRPLEYD 274
21 -35.1003by5_A mol:protein length:155 Cobalamin biosynthesis protein  ali model follow..  25  2.........................................................................................................................................................................................................................SLELGQAMVTVAGIGCRKGA-ASDAIIAAVRAAERAFGV---TVDYLATAPLKADEAGLAEAAKGLSLSLVAQERLEAVAAETFSQASLDHSGSPSVSEAAALAAAGGARLVAPRLVVGDVTVAIAMTSDAP-HGSRSAIEYGEQEEG.......................................................................................................................................................................................................................................... 149
22 -32.7002w6k_A mol:protein length:145 COBE  ali model follow..  25  2........................................................................................................................................................................................................................SHMPLPIPSLLIAGIGCRRGC-SAEHLRALLERTLGEHGRSLAELDALASIDGKRDEPGLRQLATLLERPVLAPAVLHDYEPRSPSAVALRETGCSSVAEAAALALAGRADLLGAKRSDDRASIALARLL............................................................................................................................................................................................................................................................. 139
23 -30.2006mjg_A mol:protein length:420 fusion protein of dbOphMA and methylated peptide  ali model follow..  11  11.............................................................................................................................................................................................................................................................................................................................................................KPGSLIVVGTGIESIGQMTLQALSYIEAASKVFYVIDPATEAFILTKNKNCVDLYQRMDTYTQMAELMLKEVRNGLDVVGVFYGHPGVFVNPSHRAAIARSEGYQARMLPGVSAEDCLFADLCIDPSNPGCASDFLIRERPVNVHSHLILFQVGCVGIADFNFSGFDNSKFTILVDRLEQEYGPDHTVVHYIAAMMPDPVTDKFTIGQLREPEIAKRVGGVSTFYIPPKARKDINTDII........... 264
24 -30.0002bb3_A mol:protein length:221 cobalamin biosynthesis precorrin-6Y methylase (cbiE)  ali model follow..  19  5....................................................................................................................................................................................................................................................................................................................................................SSGRENLYFSGHMIWIVGSGTCRGQ-TTERAKEIIERAEVIYGSRRAL-ELAGVVDDSRARILRSFKGDEIRR----IMEEGREREVAVISTGDPMVAGLGRVLREIAEDVEI--KIEPAISSVQVALARLKVDL-----SEVAVVDCHAK----DFDAELTELLKYRHLLILADSHFPLERL---------GKRRVVLLENLCMEGERIREGNADSIEL------ESDYTIIFVEREVM................... 212
25 -29.6005n0n_A mol:protein length:410 Peptide N-methyltransferase  ali model follow..  12  2........................................................................................................................................................................................................................................................................................................................................................TSTQTKAGSLTIVGTGIESIGQMTLQALSYIEAAAKVFYIDPATEAFILTKNKNCVDLFQYYDNGKTQMSELMVREVRKGLDVVGVFYGHPGVFVNPSHRAAIAKSEGYRARMLPGVSAEDCLFADLCIDPSNPGCASDFLIRDRPVSIHSHLVLFQVGCVGIADFNFTGFDNNKFGVLVDRLEQEYGAEHPVVHYIAAMMPDPVTDKYTVAQLREPEIAKRVGGVSTFYIPPKARKASNLDII........... 260
26 -25.1005hw4_A mol:protein length:248 Ribosomal RNA small subunit methyltransferase I  ali model follow..  15  2...............................................................................................................................................................................................................................................................................................................................................................GQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLP------SDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVL........................ 220
27 -22.8003kwp_A mol:protein length:296 Predicted methyltransferase  ali model follow..  18  16...............................................................................................................................................................................................................................................................................................................................................................GHLYLVPTPIGNLDDMTFRAVKTLTAVDLIAAEDTRNTQKLLNHFEITTKQISFHEHNTQERIPQLIAKLKQGMQIAQVSAGMPSISDPGHELVNACIDAHIPVVPLPGANAGLTALIASGLA------PQPFYFYGFLDRKPKDRKAEIAGLAQRPETLIFYEAPHRLKKTLQNLAAGFGDERPAVLCRELTKRYEEFLRGSLAELANWAATDTVRGEFVVLVGGNPAPTTA............... 243
28 -20.5001wyz_A mol:protein length:242 putative S-adenosylmethionine-dependent methyltransferase  ali model follow..  11  2..............................................................................................................................................................................................................................................................................................................................................................ETALYLLPVTLGDTPLLPSYNTEIIRGIRHFIVEDVRSARRFLKKVDDSLTFYPLNKHTSPEDISGYLKPLAGGASMGVISAGCPAVADPGADVVAIAQRQKLKVIPLVGPSSIILSVMASGFNGQSFAFHGYLPIEPGERAKKLKTLEQ--RVYAESQTQLFIETPYRNHKMIEDILQNCRPQTKLCIAANITCEGEFIQTRTVKDWKGHIPELSKIPCIFLLYK....................... 234
29 -16.4003hh1_A mol:protein length:117 Tetrapyrrole methylase family protein  ali model follow..  18  5..............................................................................................................................................................................................................................................................................................................................................................KGTLYVVATPLGNLDDMTFRAVNTLRNAGAIACEDTRRTSILLKHFGEGKRLVSYHSFNEERAVRQVIELLEEGSDVALVTAGTPAISDPGYTMASAAHAAGLPVVPVPGA.......................................................................................................................................... 117
30 -13.8003fq6_A mol:protein length:115 Methyltransferase  ali model follow..  16  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................NATAFVPALVASGLPNEK-------FCFEGFLPQKKGRQTRLKALAEEHRTMVFYESPHRLLKTLTQFAEYFGTERQATVSREISKLHEETVRGSLAELIEHFTATEPRGEIVIVLAGI..................... 113
31 -13.8003ffy_A mol:protein length:115 Putative tetrapyrrole (Corrin/porphyrin) methylase  ali model follow..  17  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................NATAFVPALVASGLPNEK-------FCFEGFLPQKKGRMTKLKSLVDEHRTMVFYESPHRLLKTLTQFAEYFGPERQVSVSREISKIHEETVRGTLSELIEHFTATDPRGEIVIVLAGI..................... 113

FFAS is supported by the NIH grant R01-GM087218-01
1 2 6 4 9 8   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.