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Query: gi|15894672|ref|NP_348021.1| phosphoribosylaminoimidazole synthetase (CA_C1393) [Clostridium acetobutylicum ATCC 824] (Range: 1-332), from C.acetobutylicum

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVTYKDSGVNIEEGYKSVKLMKDYASKTFIPGVINNLGSFAGMFEIGSGYKNPVLVSGTDGVGTKLAVAFATKKYDTVGIDCTAMCVNDILCHGAKPVFFLDYIACGKLEAEVASDLVKGVSEGCSQAGCALIGGETAEMPGFYKEGEYDLAGFAVGLVDKDKIIDGSKIEDGNVLIGIASSGIHSNGYSLVRKLITDFNEEFNGKKIGEVLLTPTKIYVKPVLKVLESFDVKGMAHITGGGFYENIPRMFKGDFTAVINKESLEIPEIFKHIMSLGVDENHAFNTFNMGIGFVICAAKEDKDGIIASLKESGEKAYEIGYVKAGGSGVCIKLast
1 -78.700sp|P22102|PUR2_HUMAN Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens GN=GART PE=1 SV=1 (Range: 451-750)  ali follow..  47  1.................VKKIQPLAKATSRSGCKVDLGGFAGLFDLAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLHLERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQGHLSEEEMARTFNCGVGAVLVVSKEQTEQIL.......................... 300
2 -51.300sp|P22102|PUR2_HUMAN Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens GN=GART PE=1 SV=1 (Range: 301-600)  ali follow..  54  135.LTYKESGVDIAAGNMLVKKIQPLAKATSRSGCKVDLGGFAGLFDLAAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKL....................................................................................................................................................................... 299
3 -46.900sp|Q99611|SPS2_HUMAN Selenide, water dikinase 2 OS=Homo sapiens GN=SEPHS2 PE=1 SV=3  ali follow..  15  107..........................GPSPTFPALGIGMDSCVIPLRHG--GLSLVQTTD------FFYPLVEDPYMMGRIACANVLSDLYAMGITECDNMLMLLSVEEREKVTPLMVKGFRDAAEEGGTAVTGGQTVVNPWI------IIGGVATVVCQPNEFIMPDSAVVGDVLVLTKPLGTQVAVNAHQWNKVKMVVSREEVELAYQEAMFNMATLNRTAAGLMHTFNAHAATDITGGILGHSQNLAKQQRNEVSFVIHNLPIIAKMAAVSKASG---RFGLLQGTSAGLLICLPREQAARFCSEIKSSGHQAWIVGIVEKGNRTARI. 416
4 -46.500sp|P49903|SPS1_HUMAN Selenide, water dikinase 1 OS=Homo sapiens GN=SEPHS1 PE=1 SV=2  ali follow..  14  27......KGTGCKVPQDVLQKLLESLQFLGAVMPRLGIGMDTCVIPLRHG--GLSLVQTTDYIYPIVDD------PYMMGRIACANVLSDLYAMGVTECDNMLMLLGVRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWI------VLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETGLLICLPREQAARFCAEIKSPGHQAWIIGIVEKGNRTARI. 366
5 -38.900sp|P22102|PUR2_HUMAN Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens GN=GART PE=1 SV=1 (Range: 601-900)  ali follow..  39  2......................................................................................................................................................................LERITEGDVVVGIASSGLHSNGFSLVRKIVAKSSLQYSDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPEKLGVDLDAQTWRIPRVFSWLQQGHLSEEEMARTFNCGVGAVLVVSKEQTEQILRDIQQHKEEAWVIGSVVARAEGS... 173
6 -21.000sp|O15067|PUR4_HUMAN Phosphoribosylformylglycinamidine synthase OS=Homo sapiens GN=PFAS PE=1 SV=4 (Range: 301-600)  ali follow..  10  4......................................................VVFTAETHNFPTGV-----CPFSGATTGTGGRIRDVQCTGAHVVAGTAGYCFGNLHIPVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRRIMFSGGIGSMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPEMEIRACVEAPKGNPICSLHDQGAGGNGNVLELSDPAGAIIYTSRFQ---------LGDPTLNALEIWGAEYQE-SNALLLRSPNRDFLTHVSARERCPACFVGTIT-GDRRIVL. 300
7 -17.800sp|O15067|PUR4_HUMAN Phosphoribosylformylglycinamidine synthase OS=Homo sapiens GN=PFAS PE=1 SV=4 (Range: 751-1050)  ali follow..  12  2.........................................................................................VFALVTDLRDVKCSGNWLPGEGAALADACEAMVAVMAALGVAVDGGKDSLSMAARVGTE-SLVISAYAVCPDITATVTPDLKHPELLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENL----VRAFSITQGLLKDRLLCSGHDVSDGGLTCLLEMAFAGNCGLQVDVPVPRVDV--------------LSVLFAEEPGLVLEVQEPDLAQVLKRYRDAGLHCLELGHTGEAGPHAMVR 241
8 -9.040sp|O15067|PUR4_HUMAN Phosphoribosylformylglycinamidine synthase OS=Homo sapiens GN=PFAS PE=1 SV=4 (Range: 451-750)  ali follow..  10  2....................................................................................................................................VGGPV---------YRIGVGGGAASSVDNTSDLDFGAVQRGD---------------PEMEQKMNRV--------------------IRACVEAPKGNPICSLHDQGAGGNGNVLKELSDPA-GAIIYTSRFQ-------LGDPTLNALEIWGAEYQE-SNALLLRSPNRDFLTHVSARERCPACFVGTITGDRR..... 147
9 -8.560sp|O15067|PUR4_HUMAN Phosphoribosylformylglycinamidine synthase OS=Homo sapiens GN=PFAS PE=1 SV=4 (Range: 601-900)  ali follow..  10  62..............HQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIGAATALGEQAVAEALTNLVFALVTDLRDVKCSGNWMWAAKALADACEAMVAVMAALGVAVDGGKDSLSMAARVGTE-SLVISAYAVCPDTATVTPDLKHPEGRGVALSPGQHRLGGTALAQ........................................................................................................................................... 270
10 -7.970sp|O15067|PUR4_HUMAN Phosphoribosylformylglycinamidine synthase OS=Homo sapiens GN=PFAS PE=1 SV=4 (Range: 151-450)  ali follow..  14  93.........GQKLVHSLFESIMSTQESSNPNNVLKFCDNSSAISRFQQQQGLRHVVFTAETHNFPTGVCPFSGATTGTG------RIRDVQCTGAHVVAGTAGYCFGNLHIEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQ--MFSGGIGSMEADH-ISKEAPEPGMEVV........................................................................................................................................................... 300

FFAS is supported by the NIH grant R01-GM087218-01
1 3 1 8 9 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.