current user: public

Please be advised that we have recently moved our server to a new location. We tried our best to fully test all functions on the website, but if something does not work for you please let us know.

Query: [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340
# Score Template Links and tools%idFirst MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRVLast
1 -140.000[J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit  ali  100  1MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRV 344
2 -70.300[J] KOG2783 Phenylalanyl-tRNA synthetase  ali follow..  25  1.......................................................MFPHRVSHLSKLFSRRFPNWKRKVQT---DSWSNVPEHIHSKIGRNLFQKEGHPICSLRQLLEQQFQKFEMNVQKESPIVSVETNFDSLGFPKTHVSRSKSDTYYMNNKTCLRTHTSAHQPEEFSRKEGFKKNGFLITADVYRRDEVDSSHYPIFHQMEGALVWNRNDTAKMKNDLKKVALSPSLKSMVDDETTALETHNDMQDIYSLEETKFPSFQLEIDWKGKWLEILGCGVVQDRLLKGAGLNN--YIGWAFGIGLERLAMILYGIPDIRLFWSLDERFSKQFLP. 329
3 -68.000[J] COG2024 Phenylalanyl-tRNA synthetase alpha subunit (archaeal type)  ali follow..  21  1MKFDPQKYRELAEKDFEAA-------WKAGKEILAERSPNELYPRVGFSFGKEHP-LFATIQRLREAYLSSEVVNPLIVEDVHVKKQFGREALTLPKPNVGISAEKIRQIEAISKPLQEIFHRYKKGEIDGDDLS--YLIAEVLDVDDITAVKILDEVFPISSTLTLRSHMTTGWFITLSHDKLPLPIKLFSIDRCFRREQEDATRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQTEVFAFHPKLVGSSTKYSDGWIEIATFGIYSPTALAEYDIP---YPVMNLGLGVERLAMILYGYDDVRKMVYSDLDIAREIK.. 367
4 -58.800[J] KOG2784 Phenylalanyl-tRNA synthetase, beta subunit  ali follow..  24  176...SVDKGRVVRQATEVTDSTRKQLESLRIGSSDVSENEKKELKKRKLISEVNIKAL-SKGTSFTTSLAKQEADLTPEMIASGSWKDMQFKKYNFDSLGVVPSSGHLHPLMKVRSEFRQIFFSMGFEMATNRYVESSFWNFDALFQPQQHPARDAHDTFFVSDKNVLRTHTTAVSARQLYQQEGFRPSKLFSIDRVFRNETLDATHLAEFHQVEGVIAEKNLSLAHLIGIFTEFFKKL----TNLRFKPTYNPYTEPSMEIFAYHQGLT----------KWVEIGNSGMFRPEMLLPMGLPAD-VNVAGYGLSLERPTMIKYGINNIRDLFGSKIDLNVVYN.. 544
5 -9.950[J] KOG2472 Phenylalanyl-tRNA synthetase beta subunit  ali follow..  13  317..............................DSIGVSLKVEQVTSLLTRMQLQAEQAKSSDNQCAIKVHVPPS--RSDVLHPCDVMEDVAIAYGFNNIPTRKPASIKPLTLNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDVNSAVIVGNPR--ADFEAMRRALMPGLLKTVGHNNKYPPIKIFEISDVVMLDESKDVGASNRRHLAALYCGATSGFELIHGLVDRIMEVM-NEKDGYYVKLSQEPEFLP------------GRQASIIVRGKHIGNFG--IVHPEVLNNFDIPDPCS---YLELDIEAI........................... 597
6 -6.370[J] COG0072 Phenylalanyl-tRNA synthetase beta subunit  ali follow..  13  213LHTDASHRYERGVDPALQYKAMERATRLLIDICG--GEAGPVIDITNEATLPKRATITLRRSKLDRLIGHHIADEQDILRRLGCEVTEGKDEWQAVAPSWRFD------MEIEEDLVEEVARVYGYNLNDKGYQEVITYSFVDPKVQQMIHPGVEALLLISVEMSAMRLSLWTLATVVYNQNRQQNRVRIFESGLRFVPDTQAPLGIRQDLMLAGVICGETVDFYDLKGDLESVL-DLTGKLNEVEFRAEANPALHPGQSAAIYL-----------ERIGFV-----GVVHPELERKLDLNGRTL---VFELEWNKLA.......................... 551
7 -6.080[J] COG1190 Lysyl-tRNA synthetase (class II)  ali follow..  14  89.........QDVGGRIQLYVSRDDLPEGVYNEEFKKWDLGDILGARGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGLADQETRYRQRYLDLIANDESRHTFKVR--SQVMSGIRSFMVEKGFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAPELYLKRLVVGGFERVFE-------------NRNFRNEGVSPRHNPEFTMME-AYADYKDLIVLTEELFRTLTETILG-SSVVQYGEQTFDFGKPRPETNVADLDDMDKAVAIAESLGFEETAESHLIQPTFIRRNDDNPFITDRFEFFIGGREIG----GFSELNDAEDQAQRFADQVSA. 446
8 -5.830[P] KOG1120 Fe-S cluster biosynthesis protein ISA1 (contains a HesB-like domain)  ali follow..  14  1...............................................................................................................................................MKASQILAAAAARVGPALRKQVLTLTDEAASRVHHLLQQRQKPFLRL-CNGLSYTLNYADEKG-----KFDELVEEKGVRLVEPKALMHVIGTKMDFVDDKLR---SEFVFINPNSQGQCGC----GESFMTTSTSS................................................................ 131
9 -5.650[J] KOG1885 Lysyl-tRNA synthetase (class II)  ali follow..  18  180..............................DIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGL----------KDKETRYRQRYLDLILNDFVRQKFIIR--SKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYE-------------GRQFRNEGIDLTHNPEFTTCE-AYADYHDLMEITEKMVSGMVKHITG-SYKVTYHPD-VDFTPPFRRINM................................................................................. 396
10 -5.530[R] COG0655 Multimeric flavodoxin WrbA  ali follow..  16  32......................................................................................................................................................................IETEIFQIGTKPVRGCIGCGTCSKTGSGKCVFDDDTLNAGLEKAKTADGFIFGSPVHYAAASGALTSFLDRFFYAGKDFAYKPG----------AAIVSCRRGGAAAAFDQLNKYFTIANMPIV-----------SSQYWNMVHGNTPEEVKQDLEGMQTMRTLGKNMAWLLKSIQ.. 186

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 5 2 3   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.