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Query: [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit, from COG0516

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRVLast
1 -78.300sp|O95363|SYFM_HUMAN Phenylalanyl-tRNA synthetase, mitochondrial OS=Homo sapiens GN=FARS2 PE=1 SV=1  ali follow..  27  2....................VGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECAQRAPGSVVELLGKSYPQDDHSNLTRK------VLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYFSVYDNSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDA----FLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINF------------HGEWLEVLGCGVMEQQLVNSAGAQD--RIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFC.. 344
2 -58.400sp|Q9Y285|SYFA_HUMAN Phenylalanyl-tRNA synthetase alpha chain OS=Homo sapiens GN=FARSA PE=1 SV=3  ali follow..  26  130..DSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEV----------TLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDKNLLRTHTTSASARALYRKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL----TQLRFKPAYNPYTEPSMEVFSYHQGLK----------KWVEVGNSGVFRPEMLLPMGL-PENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYD.. 489
3 -54.300sp|Q9BRP7|FDXA1_HUMAN Ferredoxin-fold anticodon-binding domain-containing protein 1 OS=Homo sapiens GN=FDXACB1 PE=2 SV=3 (Range: 301-600)  ali follow..  17  3.............................................................................................................................LTGGTSQDVEDFLVSFSELSLLKNPGRDEACEGTCGQAKICLRPSLLVHVQDVIEVPDFLSGSLHILSGPVFQKCHILPFTMPAFHETLFILGVNQSLLDHLKGILDSLLTQTLPESSKLSLVKFVLQSNGKDYMIRVKTHNFSPD---------CTEDLIIGSVITSAT---SVIHKDQCFVFVSMNLDLLAMLVWCISDWRMLWTFDNRFLKNFVP. 220
4 -15.400sp|Q9BRP7|FDXA1_HUMAN Ferredoxin-fold anticodon-binding domain-containing protein 1 OS=Homo sapiens GN=FDXACB1 PE=2 SV=3 (Range: 451-624)  ali follow..  27  8.....................................................................................................................................................................................................................................................................................SPDCTEDLIIGSVITSATSVIHKD---QCFVFVSMNLDLLAMLVWCISDWRMLWTFDNRFLKNFV.. 69
5 -11.400sp|Q9NSD9|SYFB_HUMAN Phenylalanyl-tRNA synthetase beta chain OS=Homo sapiens GN=FARSB PE=1 SV=3  ali follow..  12  316..............................KKVGIRETPENLAKLLTRMYIGDGNQIEIEIPPTRADIIHACD-------VEDAAIAYGYNNIQMTLP-KTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYVIKASEGPAF---------PGRCAEIFARGQSVGKLG--VLHPDVITKFELTMPCS---SLEINVGPF........................... 588
6 -7.330sp|Q9H8W4|PKHF2_HUMAN Pleckstrin homology domain-containing family F member 2 OS=Homo sapiens GN=PLEKHF2 PE=1 SV=1  ali follow..  13  2...................................................................VDRLANSEANTRRISIVENCFGAAGQPLTIPGRVIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHI--NKCVTDLLSKSGKTPSNEHAAVWVPDSEATVC-------------------MRCQKAKFTPVNRRHH----CRKCGFVVCGPCSEK................................................................. 189
7 -6.790sp|Q96S99|PKHF1_HUMAN Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens GN=PLEKHF1 PE=1 SV=3  ali follow..  11  2...................................................................VDHLANTEINSQRIAAVESCFGASGQPLALPGRVLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHI--EECVRRQLRATGRPPSTEHAAPWIPDKATDIC-------------------MRCTQTRFSALTRRHH----CRKCGFVVCAECSRQ................................................................. 189
8 -6.710sp|Q86YW0|PLCZ1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 OS=Homo sapiens GN=PLCZ1 PE=2 SV=1 (Range: 301-600)  ali follow..  13  1........................................................IGTLKETHERKGSDKRGDNQDKETGVKKLPGVMLF---------KKKKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQQFNENNSIGETQARKLSKLRVHEFIFHTRKFITRIYPKATRA--DSSNFNPQEFWNIG---------CQMVALNFQTPGLPMDLQNGKFLDNGGSGYILKPHFLRESKSYFNPSNIKEGMPIT---LTIRLISGIQLPLTHSSS-IEVFGQMKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNE--FLGQY... 271
9 -6.700sp|Q9P212|PLCE1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 OS=Homo sapiens GN=PLCE1 PE=1 SV=3 (Range: 1651-1950)  ali follow..  14  4.............NKKESRQIAPELSDLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCR--RYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN---------------------------------YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLT-SGQNVCPSNS-VDVLGSCHFRTKPIHRNTLNPMWNEQFLFHVHFEDLVFLRFAVVE.................. 292
10 -6.670sp|Q8N3E9|PLCD3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 OS=Homo sapiens GN=PLCD3 PE=1 SV=3 (Range: 451-750)  ali follow..  13  12................PNPEELPSPEQLKGRVLVKGKKLPAARSEDGRALSDR---------EEEEEDDEEEEEEVEAAAQRRLAKQISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALN---------------------------------FQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEYPGPPRTTLSIQVLTAQ-AEKPHSIVDPLVRIEIHGCARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPND--FVGQ.... 300

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 5 2 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.