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Query: [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family, from COG0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAIRRASVNLAWEHCRFPWDFDVRERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRCLTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGSRYDHGTMFYHAPNEGLIDAAHSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYAPGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYMQGAKKGLast
1 -116.0001gq6_A mol:protein length:313 PROCLAVAMINATE AMIDINO HYDROLASE  ali model follow..  37  2...ERIDSHVSPRYAQIPTFMRLPHDPQPR--GYDVVVIGAPYDGGTSYRPGARFGPQAIRSESGLIHGVGI--DRGPGTFDLINCVDAGDINLTPFDMNIAIDTAQSHLSGLLKANAAFLMIGGDHSLTVAALRAVAEQHGPLAVVHLDAHSDTNPAGGRYHHGTPFRHGIDEKLIDPAAMVQIGIRGDYARGHGVRVVTADEFGELGVGGTADLIREKVGQRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCVGDLKPVGFDVMEVSPLYDHGGITSILATEIGAELLYQYARAH. 309
2 -116.0003nip_A mol:protein length:326 3-guanidinopropionase  ali model follow..  35  5.HPQPLDAAEIPRFAGIPTFMRLPAFTDPA--ALQVGLIGVPWDGGTTNRAGARHGPREVRNLSSLMRKVHH--VSRIAPYDLVRVGDLGDAPVNPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGR-ERPLGMVHFDAHSDTNDRDNPYTHGTPFRRAIEEGLLDPLRTVQIGIRGAFARECGIRVIHMEEFVELGVEATLAEARRVVGAGPTYVSFDVDVLDPAFAPGTGTPEIGGMTSLQAQQLVRGLRGLDLVGADVVEVSPPFDVGGATALVGATMMFELLCLLAESA. 314
3 -115.0003nio_A mol:protein length:319 Guanidinobutyrase  ali model follow..  37  5.LHQPLGGNEMPRFGGIATMMRLPHVQSPAELDLDAAFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNM--ATGAAPFDSLNVADIGDVAINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRANWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLPGVV. 317
4 -110.0004dz4_A mol:protein length:324 Agmatinase  ali model follow..  43  18..PSVYGSSIENTYAGVLSFMRRNYTRDLD--GVDVVVSGVPLDLATTFRSGARLGPSAVRAASVQLAELNP-YPWGFDPFDDLAVIDYGDCWFDAHHPLSIKPAIVEHARTILQSDARMLTLGGDHYITYPLLIAHAQKYGPLSLIHFDAHCDTWADPDSLNHGTMFYKAVKDGLIDPKASVQVGIRTWNDDYLGINVLDAAWVHEHGARATLERIESIVGGRPAYLTFDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGVNLIGADVVEVAPAYDQSEITAIAAAHVACDLLCLWRQRK. 320
5 -98.7001wog_A mol:protein length:305 agmatinase  ali model follow..  26  1.....MSGPAHLPYGGIPTFARAPLVQPDGDWQADVAALGVPFDIALGFRPGARFAPRALREASLRSV-PPFTGLDGKTRLQGVTFADAGDVILPSLEPQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFAD-VPDLHVVQLDAHLDFTDTDTKWSNSSPFRRAC-EALPNLVHITTVGLRGAAARARGHTIIPMDDVT----ADLAGVLAQLPRGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVFDHV. 304
6 -92.3003lhl_A mol:protein length:287 Putative agmatinase  ali model follow..  28  2...........................SLNYEESNLIVFGVGFDGTTSNRPGARFASSSMRKEFYGLETYSPFLD---LDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREENSKNSHATVIKRIWD--IVGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKI. 278
7 -88.6004rhi_A mol:protein length:351 Arginase  ali model follow..  22  2..........GSSSSGLVPRGSHMFSKF-----LMNVKGVTPRGSDWANRPVALFGYGAMPRRAPLLD-FFLQSPRDCDHYAELTIHDKGPIECPPETVMFMPVLNCEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFDDIVIVHFSARPSVSD------PRSPLRVLLDKGLLK--GVVSVGNRQKVRKLHKMFYMDMHAIYSKG----LFCIRDIRNDYPVFISIDASVLDPAFAPAVDSPVAGGLSTRDLLHIMNGIRGPKVVGIDVYGYNPDLDNVGLTAIALSKIIKEGILKAYSIS. 317
8 -87.0003m1r_A mol:protein length:322 Formimidoylglutamase  ali model follow..  24  7.YPFLREAGSSFKDRDVTKMSDLIATWD-GQDIKGPALIGVPLSKSSISHSGASFAPGTIRQALKHSSAYSAELGEHV---VSELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNT-GGPTNGTPFRRLLDEEIIEGQHLIQLGIREAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDKTIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIQQPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSP. 320
9 -86.0004rhm_A mol:protein length:351 Arginase  ali model follow..  23  8.............LVPRGSHMFSKFLMN--------VKGVTPRGSDWANRPVALFGYGAMPRRAPLLD-FFLQSPRDCDHYAELTIHDKGPIECPPETVMEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFDDIVIVHFDAHPDVSD------PRSPLRVLLDKGLLK--GVVSVGNRQKVRKLHKMFYMDMHAIYSKG----LFCIRDIRNDYPVFISIDADVLDPAFAPAVDSPVAGGLSTRDLLHIMNGIRGPKVVGIDVYGYNPDLDNVGLTAIALSKIIKEGILKAYSIS. 317
10 -81.8003pzl_A mol:protein length:313 Agmatine ureohydrolase  ali model follow..  26  3...LGGNGREKDHASELRSIFSLKKIADAVNGEAKYVVFGIPFDNTSSYRRGSKYAPDSIRGAYVNLESYEYSYGIDL---LASGMADLGDMEES-EDVEYVIDTVESVVSAVMSDGKIPIMLGGEHSITVGAVRAL---PKDVDLVIVDAHSDFRSSGNKYNHACVTRRALD--LLGEGRITSIGIRSEDPDFRKVSFISSFDVKKNGIDKYIEEVDR--KSRRVYISVDMDGIDPAYAPAVGTPEPFGLADTDVRRLIERL-SYKAVGFDIVEFSPLYD-NGNTSMLAAKLLQVFIASREKYY. 301
11 -75.5002a0m_A mol:protein length:316 ARGINASE SUPERFAMILY PROTEIN  ali model follow..  21  4...........AARTDDPRLLSLFSAQREE--DADIVIIGFPYDEGCVRRAGAKKGPAAFRFFLQRLGSVNNLE--LNVDASHLKLYDAGDITAS--TLEEAHEKLESKVFTVLARGAFPFVIGGGNDQSAPNGRAMLRAFGDVGVINVDSHLDVRPPDGRVHSGTPFRQLLEESSFSGKRFVEFACQGQYVRDHQGHLMWLSEVRKKGAVAALEDAFGLTGK-NTFFSFDVDSLKSSDMPGVSCPAAVGLSAQEAFDMCFLAKTPTVMMMDMSELNPLVEE-YRSPRVAVYMFYHFVLGFATRP. 304
12 -66.8001xfk_A mol:protein length:336 Formimidoylglutamase  ali model follow..  19  16...DPEDGQAGRRVHHIACPIQVG---ELANQEPGVALIGFECDAGVERRTGAKHAPSLIKQALANLA-----------WHHPIPIYDLGNIRCEGDELEQAQQECAQVIQQALP-HARAIVLGGGHEIAWATFQGLAQKQPRIGIINFDAHFDLRTFPVRPSSGTPFNQIHHFCQQQDFHYACLGVSRERADKLGVWYVEDKAFSPLSLKDHLTQLQHFIDDDYLYLTIDLDVFPAASAPGVSAPAARGVSLEALAPYFDRILHYKLMIADIAEYNPSFDIDQHTARLAARLCWDIANAMAEQV. 330
13 -45.6001pq3_A mol:protein length:306 Arginase II, mitochondrial precursor  ali model follow..  26  2..................................SVAVIGAPFSQGQK-RKGVEHGPAAIREAGLMKRLSSLGC----------HLKDFGDLSFNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSHGQPVSFLLRELCISSASIVYIGLRDVDPKNYDIQYFSMRDIDRLGIQKVMERTFDLLRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQT. 303
14 -44.4001t5f_A mol:protein length:314 Arginase 1  ali model follow..  26  2..................................PIEIIGAPFSKGCP-RGGVEKGPAALRKAGLVEKLKETEY----------NVRDHGDLAFNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLAVIWVDAHTDINTPLTTSSAGQPVAFLLKELAISAKDIVYIGLRDVDPKTLGIKYFSMTEVDKLGIGKVMEETFSYLKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSAFGTK. 302
15 -44.3004ity_A mol:protein length:330 Arginase  ali model follow..  20  2...........................RGSGMAKKMSIVLAPFSGGQP-HSGVELGPDYLLKQGLQQDMEKLGW----------DTRLERVFDGRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSHGCPLSILLGLDVLKPNKIAYIGLRAVDDHDLNIAAFSMHHVDRYGIDKVVSMAIEAVGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGLVALDVVECNPLLAATESHVNDTISVGCAIARCMMGET. 313
16 -44.2001wva_A mol:protein length:322 Arginase 1  ali model follow..  24  1............................MSAKSRTIGIIGAPFSKGQP-RGGVEEGPTVLRKAGLLEKLKEQEC----------DVKDYGDLPFNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSHGQPVSFLLKELCISAKDIVYIGLRDVDPKTLGIKYFSMTEVDRLGIGKVMEETLSYLKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLA. 307
17 -43.9001d3v_A mol:protein length:323 PROTEIN (ARGINASE)  ali model follow..  25  1............................MSSKPKPIEIIGAPFSKGQP-RGGVEKGPAALRKAGLVEKLKETEY----------NVRDHGDLAFNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSHGQPVAFLLKELCISAKDIVYIGLRDVDPKTLGIKYFSMTEVDKLGIGKVMEETFSYLKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTK. 307
18 -43.6001cev_A mol:protein length:299 PROTEIN (ARGINASE)  ali model follow..  28  3..................................PISIIGVPMDLGQT-RRGVDMGPSAMRYAGVIERLERLHY----------DIEDLGDIPINLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSHGMPLAASLGFGKIKPEHVVLIGVRSLDEREKGIKIYTMHEVDRLGMTRVMEETIAYLKERGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIISAEFVEVNPILDERNKTASVAVALMGSLF........ 294
19 -43.5002eiv_A mol:protein length:291 Arginase  ali model follow..  26  3..................................RVAVVGVPMDLGAN-RRGVDMGPSALRYARLLEQLEDLGY----------TVEDLGDVPVSLARASRRRGRGLAYLEEILPEGVFPIVLGGDHSLSMGSVAGAAR-GRRVGVVWVDAHADFNTPETSPSHGMPLAVLSGLGAVDPKDVVLVGVRSLDPKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTYREAHLLMEILAESGRVSLDLVEVNPILDERNRTAEMLVGLALSLL........ 286
20 -41.5004q3p_A mol:protein length:385 Arginase  ali model follow..  21  38..................................SANFLGIPTNRGQP-KIGTYQGPELIRKSNFFQLVAEDGI----------QLTDCGDIIPWSRSFSLTTLRIAERVEELMKQSNKLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASHGMPLSFLVKELCLNASNIAYIGLRDLDARKHGIAYFTMLDVDRMGIEAVIKEALLAVLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGLSVVELAELNPLLGSQE-TQSSAVHILRACL........ 348
21 -41.2004g3h_A mol:protein length:330 Arginase (RocF)  ali model follow..  19  1...................................MILVGLEAELGASKR-GTDKGVRRLREALSATHGDVIKGMQTITQERCVLYKEFRYAKNFEDYYLFCKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKKIGILYLDAHADIHTAYDSDSHGMPLGMVLNRV-IDPKCLVYFGVRSTEQRELQIPLFSVDAI-RENMQEVVQKTKESLAVDIIYLSLDLDIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESFLKAVEVTEYNPTVSIKHNNE--EEKQVLEILDLIINSC. 309
22 -36.9003mmr_A mol:protein length:413 Arginase  ali model follow..  22  19..................................NVSIIGSPLAAGQP-LGGVQLACDDLRKLGLHNVIDVLGW----------KYEDIGNIDNNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSHGMTLAHTLGLFYLKPENTAIIGIRDIDAKKCNINYYTIFDIEKNGIYNTICTALEKISNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKVVSMDLVEYNPSLDEVDKTGKLCLELIARVL........ 402

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 1 8 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sasin JM, Godzik A, Bujnicki JM. SURF'S UP! - protein classification by surface comparisons. J Biosci. 2007 Jan;32(1):97-100.