current user: public

Please be advised that we have recently moved our server to a new location. We tried our best to fully test all functions on the website, but if something does not work for you please let us know.

Query: [J] COG0013 Alanyl-tRNA synthetase, from COG0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560    .  570    .  580    .  590    .  600    .  610    .  620    .  630    .  640    .  650    .  660    .  670    .  680    .  690    .  700    .  710    .  720    .  730    .  740    .  750    .  760    .  770    .  780    .  790    .  800    .  810    .  820    .  830    .  840    .  850    .  860    .  870
# Score Template Links and tools%idFirst MKTMTSAEVRQMFLDFFKSKGHTVEPSQSLVPVNDPTLLWINSGVATLKKYFDGSVVPENPRLTNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRKEAIAFAWELLTSSEWFEFPAEKLYITYYPADKDTYNRWVEVGVDPTHLVPIEDNFWEIGAGPSGPDTEIFFDRGEVYDPEHVGLKLLAEDIENDRYIEIWNIVLSQFNADPSIPRSEYPELPQKNIDTGMGLERMVCIIQGGKTNFDTDLFLPIIREIEKLSGKTYSPDSENMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRAVMHGKKLGIQGKFLASLVPTVGKIMQSYYPEVLEKEDFIMQIIDREEETFNRTIDAGQKLIDELLLNLKSEGKDRLEGADIFRLYDTYGFPVELTEELAEDEGFKIDHEGFKVAMKAQQERARAAVVKGGSMGAQNETLSSIEVESEFLYEDKTTQGKLLVSIQDDEIVDEVSGKAQLVFDVTPFYAEMGGQVADHGVIKDAEGQVVANVLDVQHAPHGQNLHSVETLSPLKVGESYTLEIDKERRAAVVKNHTATHLLHAALHNIVGNHALQAGSLNEVEFLRFDFTHFAQVTKEELAEIERQVNEVIWQSLKVETVETDIATAKEMGAMALFGEKYGKNVRVVKIGDYSIELCGGTHTQTTSEIGLFKIVKEEGIGSGVRRIIAVTGQKAYEAFKDAENTLNEVATMVKAPQTSQVLAKVTSLQDELKTAQKENDALAGKLAASQSDEIFKNVQTAGSLNFIASEVTVPDANGLRNLADIWKQKELSDVLVLVAKIGEKVSLLVASKSSDVKAGNLVKELAPFVDGRGGGKPDMAMAGGSKAAGIPELLAAVAEKLALast
1 -167.0002zze_A mol:protein length:752 Alanyl-tRNA synthetase  ali model follow..  28  54PRKYTLDEMREKFLRFFEKHPHGRVKRYPVLPRWRDDVLLVGASIMDFQPWISGEADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHHAFNYYWMDETVELAFEFFT--KELKMKPEDITF--------------------------KENPWAGG-GNAGPAFEVLY-----------------------RGLEVATLVFMQYKKAPEIKGEKYIPMETKVVDTGYGLERLVWMSQGTPTAYDAVLGYVILMENSRLAGMFDIEDLGDLLIYAIADHTKALTFMLADGVVPSNVKAGYLARLLIRKSIRHLRELGLEV-PLSEIVALHIKELHKTFPEFKEMEDIILEMIELEEKKYAETLRRGSDLVRREIAKLKKKGIKEIPVEKLVTFYESHGLTPEIVKEIAEKEGVKVNPDNFYSMVAKEAERTKEEKGEEL---VDFELLKDLPDTRRLYYEDKEFDAKVLRVIKDW-----------VILDATAFYPEGGGQPYDTGVLIVNGREV--KVTNVQKV-GKVIIHKVEDPGAFKEGMIVHGKIDWKRRIQHMRHHTGTHVLMGALVRVLGRHVWQAGSQLTTDWARLDISHYKRISEEELKEIEMLANRIVMEDRKVTWEWLPRTTAEQKYGFRLYGVVPGREIRVVKIEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGE......................................................................................................................................................................... 752
2 -152.0003wqy_A mol:protein length:906 Alanine--tRNA ligase  ali model follow..  26  57KKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYYWKNETVAYCTELLN----------------------------ELGVKKEDIVYK-EEPWA-GGGNAGPCLEAIVGGLEVATMNLEEHPEGDIEIKGARYRKMDNYIVDTGYG---LERFVWASKGTPTVYDAIFPEVVDTIIDNVSFNREDERVRRIVAESSKLAGIMGELRGERLKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELG-LDLYDLVEMHKKILGFEFDV---PLSTVQEILELEKERYRTTVSKGTRLVERLVERKK-----KLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEPKDIYAELAKRHSKAEKVQEKKITLQNE------YPATEKLYYDDPTLLEFEAEVIG--------VEGDFVILNRSAFYPESGGQDNDVGYLIANGGKF--EVVDVLEA-DGVVLHVVK-GAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYGVPPGRKIRVVQVGD-DVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRV-EPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDA-DMQALQKLAERLAEK--GAVGCLMAKGEGKVFVVTFSGQ-KYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLS 902
3 -128.0001riq_A mol:protein length:465 Alanyl-tRNA synthetase  ali model follow..  44  2..SLSAHEIRELFLSFFEKKGHTRVKSAPLVPENDPTLLFVNAGMVPFKNVFLGLEKRPYKRATSCQKCLRVNDLEQVGYTSRHHTFFEMLGNFSFGDYFKKEAIEYAWEFVT--EVLKLPKEKLYVSVYKDDEEAYRIWNEIGIPSERIWRLEDNFWQMGVGPCGPSSEIYVDRGEEYE-------------GDERYLEIWNLVFMQYNRDEN---GVLTPLPHPNIDTGMGLERIASVLQGKNSNFEIDIIFPLIQFGEEVSGKKYGEKETDVALRVIADHLRAITFAISDGVIPSNEGRGYVIRRILRRAMRFGYKLGIENPFLYKGVDLVVDIMKEPYPELELSREFVKGIVKGEEKRFIKTLKAGMEYIQEVIQKALEEGRKTLSGKEVFTAYDTYGFPVDLIDEIAREKGLGIDLEGFQCELEEQRERARKHFKEAKKVKPVYSHLKELGKTSAFGAAALE..................................................................................................................................................................................................................................................................................................................................................................................................................... 459
4 -124.0003hxu_A mol:protein length:441 Alanyl-tRNA synthetase  ali model follow..  47  1..SKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRANDLENVGYTARHHTFFEMLGNFSFGDYFKLDAILFAWLLLTSEKWFALPKERLWVTVYESDDEAYEIWKEVGIPRERIIRISDNFWQMGTGPCGPCTEIFYDHGDH----IWGGPPGSPEEDGDRYIEIWNIVFMQFNRQAD---GTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGAT---DLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSG---DTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASG................................................................................................................................................................................................................................................................................................................................................................................................................................................ 440
5 -110.0004xem_A mol:protein length:475 Alanine--tRNA ligase, cytoplasmic  ali model follow..  41  17.STLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPRAANTQKCIRANDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLT--QEFGIPIERLYVTYFEADLECKQIWQNLGLDDTKILPMKDNFWEMGTGPCGPCSEIHYDRIGGRDAAHL------VNQDDPNVLEIWNLVFIQYNREAD---GILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHELNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLG--DSKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQG................................................................................................................................................................................................................................................................................................................................................................................................................................................... 468
6 -55.1001v7o_A mol:protein length:165 alanyl-tRNA synthetase  ali model follow..  23  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YSIEVRTHSALHVVKGAVVKVLGSEAKWTYSTVKGNKGVLIVKFDRKPSDEEIREIERLANEKVKENAPIKIYELPREEAEKMFGEDMYDPEDVRILKVVVIEDWNVNACNKEHTKTTGEIGPIKIRKRFRKSKGLLEIHFELLELENPSLE.................................................................................................................................................................. 159
7 -50.4003rhu_A mol:protein length:160 SC_1wnu  ali model follow..  22  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SYSIEVRTHSALHVVKGAVVKTAGSDAKTTSTYVKGNKGVLIVKAALEPDKWGIAAIEALANEKVKENAPIKIYELPREEAEKMFGEDMYDPEDVRILKVVVIEDWNVNACNKEHTKTTGEIGPIKIRKRFRKSKGLLEIHFELLE......................................................................................................................................................................... 152
8 -48.8003rfn_A mol:protein length:159 BB_1wnu_001  ali model follow..  22  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YSIEVRTHSALHVVKGAVVKAAGSAAKTTSTYVKGNKGVLIVKAALELDKWAWAAMEALANEKVKENAPIKIYELPREEAEKMFGEDMYDPEDVRILKVVVIEDWNVNACNKEHTKTTGEIGPIKIRKRFRKSKGLLEIHFELLE......................................................................................................................................................................... 151
9 -45.9003g98_A mol:protein length:111 Alanyl-tRNA synthetase  ali model follow..  25  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KEENVGDFTLHYGVFEEVEPEELRNLADMLRQRTKKDVVFIASRKGDKINFVIGVSKEKVNAKEVIREVGKVLKGGGGGRADLAQGGGKAPDKFPEAVKLLKEILS 110
10 -42.1002e1b_A mol:protein length:216 216aa long hypothetical alanyl-tRNA synthetas  ali model follow..  30  26......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RDNAILLDQTIFYPTGGGQPHDRGTING------VEVLDVYKDEEGNVWHVVKEPEKFKVGDEVELKIDWDYRYKLMRIHTGLHLLEHVLNEVLGEGWQLVGSGMSVEKGRYDIAY-PENLNKYKEQIISLFNKYVDEGGEVKI-------------------WWEGDRRYTQIRDFEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLEMW............................................................................................................................................................................ 214
11 -33.1003kew_A mol:protein length:241 DHHA1 domain protein  ali model follow..  26  23.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VKEIDGKFHVLLDQTAFFPGGGGQMGDLGLIDG------IKVLDVYE-EEGKVYHV--LEKEPKKLKNLQCELDWERRFDGMQQHLGQHLLSGCFYDLFG--ANTCGFHLGKEISTVDIV--GFLDEKTIREAEKEANRLIFENLEVKSYAPSKKELKKVKTRRALPKTDEE-IRIVEIVGLDLNACCGVHPRNTRDLQVIKIRRWEKHKNAT-RIEYVAGNRAVS..................................................................................................................................................................... 233
12 -9.9401nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  17  7........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLETDGSIEIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIE-GGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKEL----FSNDEYDENVTLYSQGDF-TDLCRGVHVPSTAKIKEFKLLSTAG---------------AYWRGDSNNKMLQRIYGTAFFDK-KELKAHLQMLEERKERDHRKIGK......................................................................................................................... 248
13 -9.6404v1a_c mol:protein length:334 MITORIBOSOMAL PROTEIN ML39, MRPL39  ali model follow..  11  45.......................................................................................................................................................................................................................................................................................................................................................................................................................................FNKEKNRQLSLTPRTEK------------------IEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDDDPGEVNKAY-----------------------------RSCAMMMGCVIERAFKDEYVVS---VIAGAFCYDVV---MPTKENLHSFTKDARALIYKDLPFETLEVEAKVALEIFQHNKYSQNPERIVKLHRFGDF-IDVSEGPLIPRTSICFQYEVSAVHNLQTQSSLVRRFQGLSLPVHLRAHFTIWNKLLE....................................................................................................................................................... 314
14 -9.3703j7y_7 mol:protein length:338 mL39  ali model follow..  13  48.......................................................................................................................................................................................................................................................................................................................................................................................................................................FNKEKARQLSLTPRTEK------------------IEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAY-----------------------------RSCAMMMGCVIERAFKDEYMVN---VISGAFCYDVV---MPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFERIVKLHRIGDF-IDVSEGPLIPRTSICFQYEVSAVHNLQPTIRRFQGVSLPVHLRAHFTIWDKLLERSRKMVTEDQS............................................................................................................................................... 329
15 -9.2001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  14  5........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVID-NGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARET--FANRGESYDDKPGLYFHEEY-VDMCRGPHVPNMRFCHHFKLMKTAG---------------AYWRGDSNNKMLQRIYGTAWADK-KALNAYLQRLEEAAKRDHRKIGK......................................................................................................................... 249
16 -9.0503cc2_Z mol:protein length:116 50S ribosomal protein L37Ae  ali model follow..  16  27...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SKSGKTGSSGRFGARYGRVSRSEMNEDHACPNCGEDRVDRQG-TGIWQCSYDYKFTGGSYKPETPGGKTVRRSIRAALSEDEE.......................................................................................................................................................... 116

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 1 8 9   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sasin JM, Godzik A, Bujnicki JM. SURF'S UP! - protein classification by surface comparisons. J Biosci. 2007 Jan;32(1):97-100.