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Query: [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit, from COG0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRVLast
1 -131.0004p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit  ali model follow..  53  2..ENLDALVSQALEAVRHTEDVNALEQIRVHYLGKKGELTQVMKTLGDLPAEERPKVGALINVAKEKVQDVLNARKTELEGAALAARLAAERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQ--QPPIRIVCPGRVYRCDS-DLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNIDPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFR.. 338
2 -125.0003pco_A mol:protein length:327 Phenylalanyl-tRNA synthetase, alpha subunit  ali model follow..  51  2..SHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQ--QPPIRIIAPGRVYRNDY-DQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDV-----------MGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK.. 327
3 -123.0002rhq_A mol:protein length:294 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  68  1.............................................MGSSSSGLVPRGSHMGTELMEKLN----------------QQLAEETIDVTLPSRQISIGSKHPLTRTVEEIEDLFLGLGYEIVDGYEVEQDYYNFEALNLPKSHPARDMQDSFYITDEILMRTHTSPVQARTMEKRNGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSNEYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDVRFLEQFKAV 283
4 -123.0001b70_A mol:protein length:350 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  41  1.......MLEEALAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLTGELLLRTHTSPMQVRYMVAH--TPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWW----------PEGGKWLELGGAGMVHPKVFQAVDAYRERVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGV 349
5 -68.0002du3_A mol:protein length:534 O-phosphoseryl-tRNA synthetase  ali model follow..  21  1MKFDPQKYRELAEKDFEAA-------WKAGKEILAERSPNELYPRVGFSFGKEHP-LFATIQRLREAYLSSEVVNPLIVEDVHVKKQFGREALTLPKPNVGISAEKIRQIEAISKPLQEIFHRYKKGEIDGDDLS--YLIAEVLDVDDITAVKILDEVFPISSTLTLRSHMTTGWFITLSHDKLPLPIKLFSIDRCFRREQEDATRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQTEVFAFHPKLVGSSTKYSDGWIEIATFGIYSPTALAEYDIP---YPVMNLGLGVERLAMILYGYDDVRKMVYSDLDIAREIK.. 367
6 -67.4003cmq_A mol:protein length:415 Phenylalanyl-tRNA synthetase, mitochondrial  ali model follow..  27  2.......................................................AAECATQRAPGSVVELLGKSYPQDDHSNL------TRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDA----FLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINF------------HGEWLEVLGCGVMEQQLVNSAGAQD--RIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFC.. 308
7 -58.4003l4g_A mol:protein length:508 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  26  130..DSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEV----------TLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDKNLLRTHTTSASARALYRKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL----TQLRFKPAYNPYTEPSMEVFSYHQGLK----------KWVEVGNSGVFRPEMLLPMGL-PENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYD.. 489
8 -52.9004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  14  1................................MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELSRRKKDLQQIYAE-----ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEY-IERMGIDNDTELSK--QIFRVDKNFCLRPMLAPNLGNYLRKRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGID--FKIVGDSCMVFGDTLDVMH-----------------GDLELSSAVVGPRPLDREWGIDKP---WIGAGFGLERLLKVKHDFKNIKRAARSES-YYNGIS.. 282
9 -51.7002du7_A mol:protein length:549 O-phosphoseryl-tRNA synthetase  ali model follow..  21  3.......................................................LKHKRDDKMRFDIKKVLELAEKDFETRETRALIKDKHIDNKYPRLKPVYGKPHPVMETIERLRQAYLRMGFEEMINPVIV-DEMEIYKQFGPEAMAVLD--RCFYLAGTLTLRSHMTSGWFITLSSKKRKLPLKLFSIDRCFRREQEDRSHLMSYHSASCVVVGEDVSVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPETQTEVYAYHPKLG--------EWIEVATFGVYSPIALAKYNID---VPVMNLGLGVERLAMIIYGYEDVRAFYEYRLSDRDIAGMI 369
10 -48.7004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  15  11............................RGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESE-------------LLSRRKKDLQQIYAE-----ERENYLGKLEREITRFFVDRGFLEIKSPILI-----------PLEYIERMGIDNFRVDKNFCLRPMLAPNLYNYLRKRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLSFIQMGSGCTRENLESIITDFLNHLGID--FKIVGDSCMVYGDTLDVMH-----------------GDLELSSAVVGPIPLDREWGIDK---PWIGAGFGLERLLKVKHDFKNIKRAARSESYY....... 278
11 -47.0004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  17  2...............................................ALTKSQTDRLEVLLNPKDEISLNSGKPFR---ELESELLSRRKKDLQQIYAE-----ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEY-IERMGIDNDTELSK--QIFRVDKNFCLRPMVAPNIFNYARKRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFFQMGSGCTRENLESIITDFLNHLGIDFK--IVGDSCSVYGD---TLDVM--------------HGDLELSSAVVGPIPLDREWGID---KPWIGAGFGLERLLKVKHDFKNIKRAARSESYY....... 260
12 -46.8002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  15  11............................RGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESEL-------------LSRRKKDLQQIYAE-----ERENYLGKLEREITRFFVDRGFLEIKSPILI-----------PLEYIERMGIDNFRVDKNFCLRPMLAPNLYNYLRKRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHL----DFKIVGDSCMVYGDTLDVMH-----------------GDLELSSAVVGPIPLDREWGIDK---PWIGAGFGLERLLKVKHDFKNIKRAARSGSYY....... 278
13 -30.1003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  16  2...................................KGGLVPRGSHGASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAE-----ERENYLGKLEREITRFFVDRGFLEIKSPILI-----------PLEYIERMGIDNFRVDKNFCLRPMLTPNLYNYLRKRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLVFWQMGSGCTRENLESIITDFLNHL----DFKIVGDSCMVFGDTLDVM-----------------HGDLELSSALVGPIPLDREWGIDKPW---IGAGFGLERLLKVKHDFKNIKRAARSESYY....... 275
14 -28.9004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  16  1............................................................MPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKEERENYLGKLEREITRFFVDRGFLEIKSPILI-----------PLEYIERMGIDNFRVDKNFCLRPMLAPNLANYLRKRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHL----DFKIVGDSCMVFGDTLDVMH-----------------GDLELSSAVVGPIPLDREWGIDKPW---IGAGFGLERLLKVKHDFKNIKRAARSESYY....... 261
15 -13.5002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  14  11............................RGSHMFLTRRDPPLSSFWTKVQYQRLKELNASGEQLEMGFSDALSRDRAFQGIEHQLMSQGKRHLEQLRTVKH-----RPALLELEEKLAKALHQQGFVQVVTPTII----TKSALAKMTIGEDHPLFSQVFLDGKKCLRPMLAPYTLWRELERLWDKPIRIFEIGTCYRKESQGAQHLNEFTMLNLTELPLEERHQRLEDMARWVLEAAGIREFELVTESS----VVYGDTVDVMKGDLE---------------LASGAMGPHFLDEKWEIFDPWVGLGFGL--ERLLMIREGTQHVQLSYLDGVRL....... 299
16 -11.4003l4g_B mol:protein length:589 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  12  316..............................KKVGIRETPENLAKLLTRMYIGDGNQIEIEIPPTRADIIHACD-------VEDAAIAYGYNNIQMTLP-KTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYVIKASEGPAF---------PGRCAEIFARGQSVGKLG--VLHPDVITKFELTMPCS---SLEINIGPF........................... 588

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 7 9 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.