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Query: [J] COG0018 Arginyl-tRNA synthetase, from COG0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNVMQENQIKLIEHIKQAVVQAVGLEETEVPEILLEVPKDKKHGDYSTNIAMQLARVAKKAPRQIAESIVPELKKDTKLIKEVEIAGPGFINFYLDNAYLTDLVPVILTEDKKYGESDFGKGEKFQIEFVSANPTGDLHLGHARGAAIGDSLANIMKMAGFDVSREYYINDAGNQINNLVLSAEARYFEALGLESEFPEDGYRGSDIIALGKDLAAKYGDKYVNASEEERRSVFRVDALAFETGKLRADLEEFRVSFDEWFSETSLYEENKVLPALERLRENGYIYEQDGATWLRTTDFEDDKDRVLIKSDGSYTYFLPDIAYHLNKLERGFDVLIDIWGADHHGYIPRMRAAIEALGYSPNQLEVEIIQLVHLFEDGVQVKMSKRTGKSVTMRDLIEEVGLDATRYFFAMRSSDTHMNFDMSLAKSTSNDNPVYYVQYAHARISSILRSGKEQGLEVSKDANMSLLETEAEYDLLKVLGEFADVVAEAAVKRAPHRIVRYLNDLATAFHRFYNSNKVLDMDNLEVTKARLALIKTAQITLRNGLTLLGVSAPEKMLast
1 -125.0003fnr_A mol:protein length:464 Arginyl-tRNA synthetase  ali model follow..  39  1............................................................................................MSLSKTFLNELANQALTNPNDFTKGE-KKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESIHENVEYPEQYYKGEYIVDLAKEAFEKFGKEFF---SEENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYVSERSYY--DALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVYHKDKMSRGYGKCINIWGADHHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKMSKRAGNFILMSDVVDEIGSDALRYIFLSKKCDTHLEFDISDLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDV-MKADLQSLNQD-GVNLLFEALNLKAVLNDAFEARALQKIPDYLKNLAANFHKFYNENKVVGSAN---ENDLLKLFSLVALSIKTAFSLMGIEAKNKM 454
2 -72.7002zue_A mol:protein length:629 Arginyl-tRNA synthetase  ali model follow..  30  1..MLMEIRESVKERIEEIIKE---IAPQWEGEIELKETPDPKLGDFGTPIAFKLAKLLKRPPIEIAEKIVEKLKLNLPEGIKDVKAVNGYINVFIDYPHFARLINDILAKGDRFGSSEIGKGKKVIVEHTSVNPTKPLHMGHARNAILGDVMARILRFLGYEVEVQNYIDDLGIQFAQVYWGYLRLKEEFERIMNELRERGLKDNPIDHALGLLYVEVNRRLEDNPENEIRDIMKKLEAEEVVRAQMVTTYKLGVKYDLLVWESDIVRRKLFEIALELLSKNENFYKYRGAFVMDLRKLFPDMKNVLRRSDGTATYTGKDIAYHLWKFGKNANIVINVIGAEQKHPQLAIKYALQLLGFEDAAANLYHLAYEHVERPEG--KFSGRKGTWVTVDEVIQEVGIGAIRYNLIKYSPDKKIIFRWEDVLNEGESAP--YIQYAHARCSSILRKAEEEGIKVDPETLFKTKLSERERELVIMLSKFPRIVEQAGKDVKPHLIAWFANELASLFNKFYMDHPVLKAEE-GVREARLLLVMAVEQVLKNALYLMGIEAPERM 629
3 -68.1001iq0_A mol:protein length:592 ARGINYL-TRNA SYNTHETASE  ali model follow..  25  1..........MLRRALEEAIAQALKEMGVPVRLKVARAPKDKPGDYGVPL-FALAKELRKPPQAIAQELKDRLPLP-EFVEEAVPVG-GYLNFRLRTEAL---LREALRPKAPFP----RRPGVVLVEHTSVNPNKELHVGHLRNIALGDAIARILAYAGREVLVLNYIDDTGRQAAETLFAL-----RHYGLTWDGKEKY---HFAGRAYVRLHQDPEYERLQPAIEEVLHALERGELREEVNRI-ATMHALNARYDLLVWESDIVRAGLLQKALALLEQSPHVFRPRGALVMDASPVIEDPFFVLLRSNGTATYYAKDIAFQFWKMGPKAEETINVVDVRQSHPQALVRAALALAGYPALAEKAHHLAYETVLLEGR--QMSGRKGLAVSVDEVLEEVALGAIRFSMVKTEPKKQIDFRYQEALSEGDTGP--YVQYAHARAHSILRKAGEWGAPDLS------QATPYERALALDLLDFEEAVLEAAEERTPHVLAQYLLDLAASWNAYYNARENGQPAPEGLRELRLSLVQSLQRTLATGLDLLGIPAPEVM 592
4 -60.7001bs2_A mol:protein length:607 PROTEIN (ARGINYL-TRNA SYNTHETASE)  ali model follow..  24  30.....NIVDLMRNYISQELSKISGVDSSLIFPA-LEWTNTMERGDLL--IPIPRLRIKGANPKDLAVQWAEKFPCG-DFLEKVEANGP-FIQFFFNPQFLAKVIPDILTRKEDYGSCKLVENKKVIIEFSSPNIAKPFHAGHLRSTIIGGFLANLYEKLGWEVIRMNYLGDWGKQFGLLAVGLFDVYVRINKDIEEEGDSIPLEQSTNGKAREYFKR-----MEDGDEEALKIWKRFR-EFSIEKYIDTYARLNIKYDVYSGESQVSKE-SMLKAIDLFKEKGLTHEDKGAVLIDLTKFNKKLGKAIVKSDGTTLYLTRDVGAAMDRYEKHFDKMIYVIASQQDLHAAQFFEILKQMGFE--------AKDLQHVNFGMVQGMSTRKGTVVFLDNILEEVGISAVMIQDMQGKRINNYEFKWERMLSFEGDT---YLQYAHSRLRSVERNASGITQEKWINADFSLLKEPAAKLLIRLLGQYPDVLRNAIKTHEPTTVVTYLFKLTHQVSSCYDVLWVAG-QTEELATARLALYGAARQVLYNGMRLLGLTPVERM 607
5 -55.0004oby_A mol:protein length:578 Arginine--tRNA ligase  ali model follow..  25  2MNIQALLSEKVRQAMIAAGAPADC-------EPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLN-GIASKVEIAGPGFINIFLDPAFLAEHVQQALASDR----VATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEELADLEGFYRAKKHYDEDEEFAERARNYVVKLQSDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEIIQKKDGGYLYTTTDIACAKYRYETHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLKDGKPFK--TRAGGTVKLADLLDEVGIGAVKYADLSKNRTTDYIFDWDNMLA--EGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAP---IIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM 578
6 -53.0004zaj_A mol:protein length:601 Arginine--tRNA ligase, cytoplasmic  ali model follow..  22  1MINIISRLQEVFGHAIKAA-----YPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKVNPREIAENITKHLPDN-ECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV--NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGD---ESKKRFDTEEEFKKRAYQCVVLLQGNPDITKAWKLICDVSRQELNKIYDALDVSLIE--RGESFYQD-RMNDIVKEFEDRGFVQVDDGRKIV-----GCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEVAYGCIKYADLSHNRLNDYIFSFDKMLD-DRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETLLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 588
7 -52.6004q2t_A mol:protein length:607 Arginine--tRNA ligase, cytoplasmic  ali model follow..  23  11MASMINIISRLQEVFGHAIKAAY--PDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKVNPREIAENITKHLPDN-ECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV--NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGD---ESKKRFDTEEEFKKRAYQCVVLLQGNPDITKAWKLICDVSRQELNKIYDALDVSLIE--RGESFYQD-RMNDIVKEFEDRGFVQVDDGRKIV-----GCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEVAYGCIKYADLSRNRLNDYIFSFDKMLD--RGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETLLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 601
8 -50.5004r3z_B mol:protein length:675 Arginine--tRNA ligase, cytoplasmic  ali model follow..  23  79TKNMINIISRLQEVFGHAIKAAY--PDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKVNPREIAENITKHLPDN-ECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV--NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGD--YKSKKRFDTEEEFKKRAYQCVVLLQGNPDITKAWKLICDVSRQELNKIYDALDVSLIE--RGESFYQD-RMNDIVKEFEDRGFVQVDDGRKIV-----GCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEVAYGCIKYADLSHNRLNDYIFSFDKMLD-DRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETLLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 669
9 -34.6003gdz_A mol:protein length:109 Arginyl-tRNA synthetase  ali model follow..  34  1.SNAMNIQALLSEKVSQALIAAGA---PADCEPQVRQSAKVQFGDYQANGVMAVAKKLGMAPRQLAEQVLSHLDLN-GIANKVEIAGPGFINIFLDPAFLADNVNRAL-QSERLG......................................................................................................................................................................................................................................................................................................................................................................................................................................................... 109
10 -14.2004dlp_A mol:protein length:536 Aminoacyl-tRNA synthetase, class I:Aminoacyl-  ali model follow..  16  17........................................................................................................................SREKYYITTAIAYPNGKPHIGHAYELIATDAMARFQRLNGMDVYFLTGTDEHGIKMLQSARKEGITPRDLADRNTSAFRRMA----------EVLNSSNDDYIRTSEERHYK-----ASQAIWQAMVANGDIYKGGYAGWYSDEAYYGEEETEVRADRYGPQGTPVEEEESYFFRLSAY---QDKLLDLYENNPGFIMPDLSISRTTFDWG----IPVPGDEKH-WVDALTNYITALGYPDTTDERWAYWPANAHIIGKDIKMSKSVGNVIDPFELVERYGLDQLRYFLMREVPGQDGSYSHEAIVNRTNADLANDLGNLAQRSLSMIAKNCEGKVPQPGAF------SEADKAILDQADAALETARKAMDDQALHLALGAIFAVVAEANRYFAGQEALRKTDPARMGTVLYVTAEVLRRVGIMVQPFIPQSAEKL 486
11 -14.1004eg1_A mol:protein length:542 Methionyl-tRNA synthetase, putative  ali model follow..  13  1..................................................................................................................GPGSMKVEKVFFVTSPIYYVNAAPHIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAEAAKQKQVSPYDFTTAVAGEFKKCF----------EQMDYSIDYFIRTTNEQHKA-----VVKELWTKLEQKGDIYLGRYEGWYSDESFLTPQNITDPCKVSLESGHVVTSEENYMFRLSAF---RERLLEWYHANPGCIVPDLSVSRAR-ATLHNWAIPVPGNPDH-WLDALTNYLTGSRLRPADVHVIGKDILKLLSAGLPLKISKSLGNVFDPVEKAEEFGYDALKYFLLRESGSDDGDYSDKNMIARLNGE----------TLGNLVMRCTSAKINVNGEWPSPAAYTEEDESLIQLIKDLPGTADHYYLIPDIQKAIIAVFDVLRAINAYVTDMAVLYITLEGVRVTTLLLSPILPRKSVVIFDMLGVPEVHR. 504
12 -13.9002x1l_A mol:protein length:524 METHIONYL-TRNA SYNTHETASE  ali model follow..  15  3.......................................................................................................................GGSEPFYITTAIAYPNGVPHIGHAYEYIATDAIARFKRLDGYDVRYLTGTDVHGQKMAETAAKEGIPAAELARRNS---------DVFQRLQEKLNISFDRFIRTSDADHYEASKAIWKRMADAGDIYLDAYKYSIRDERFFTENETTE-QPDGTRIATETGAPVTWTEEQTYFFRLSAY---TDRLLALYEEHPEFIGPDLSISRTTFDWGVDHVMYVWVDALTNYLTGVPADLHMIGKDIIRFHTVYWPAFLMSAG-RGEKMSKSIGNVVDPVNLVDTFGLDQVRYFLLREVPGQDGSYNEDAIIGRVNADLANELGNLAQRSLSMVAKNLGAAVPDPGEF------TDEDTALLAAADALLERVREHFDVPAMHLALEAIWSVLGAANRYFSAQEVLRKSDAAEDQQRFR---TVLYTTLEVVRIASLLLQPVM 472
13 -13.6003kfl_A mol:protein length:564 Methionyl-tRNA synthetase  ali model follow..  14  12..................................................................................................................GPGSMKKQKVFFATTPIYYVNASPHIGHVYSTLIVDVLGRYHRVKGEEVFVMTGTDEHGQKVAEAAAKQGVSPMDFTTSVSSEFKQCF----------QEMNYDMNYFIRTTNPTHEK-----LVQDIWKKLAAKGDIYLGKYEGWYSDESFLTAQNVAKPCKVSLESGHVVTEEENYMFRLSAF---RERLLKYFHDHPNCIVPDLSISRKR-ESVMNWSIPVPGDERH-WLDALFNYYTGALTRPADVHVVGKDILKLMSAELPLKISKSLGNAFDPVEKAKEFGIDALKYFLMR-----ESNFQDDGDYSDKN-----MVARLNGELADTLGNLVSRCVAPKINVNGMW-YSESDKTLIASLNNLAGTVDHYYCLPDIQHALIAIFDVLRSLNAYVTENAVLYVTMEGLRICTMFLQPVMPQKAKEIMDALGVPEAAR. 514
14 -13.4002csx_A mol:protein length:497 Methionyl-tRNA synthetase  ali model follow..  13  1......................................................................................................................MTLMKKFYVTTPIYYVNDVPHLGHAYTTIAADTIARYYRLRDYDVFFLTGTDEHGLKIQKKAEELGISPKELVDRNAERFKKLW----------EFLKIEYTKFIRTTDPYHVKFVQKVFEECY----RGDIYLYCVGCEEFKSEAELAEDHTCPIHQKKCE-----YIKEPSYFFRLSKY---QDKLLELYEKNPEFIQPDVTRPRSRVKWGIEHTIYVWFDALFNYISALPADLHLVGKDILRFHTVYWPAFLMSLG-EGKKMSKTLGNVVDPYEVVQEYGLDEVRYFLLR-----EVPFGQD-----GDFSKKAILNRINGELANEIGNLYSRVVNMAHKFLGGEVSGARDEEYAKIAQESIKNYENYMEKVNFYKAIEEILKFTSYLNKYVDEKQPWALNKERKKEELQKVLYALVDGLFVLTHLLYPITPNK. 458
15 -13.3003h97_A mol:protein length:560 Methionyl-tRNA synthetase  ali model follow..  16  12..........................................................................................................................KKILVTCASPYANGSIHLGH---------------------------------LEHIQADVWVRYQRMRGHEVNF-ADDAHGTPIMLKAQQ-----------------LGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIYDPEKGMFLSPDQYGDNCETPVMRDSEHFFFISRDAPYFGFEIPNAPGKYFYVWLDAPIGLMGSFKNLCDKRGDSVS--TAELYHFIGVTVNGA--KMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNSRNAGFINKRFDGVLA----------SELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTY........ 497
16 -13.3003sp1_A mol:protein length:501 Cysteinyl-tRNA synthetase  ali model follow..  15  36.............................................................................................................................NVKVYACGPT--AHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGH----------------------LTGDLDDGE--------------DKVAKTAREKGLTVYE---SEFFTEAFFNDCRKLNIVYPDKVLVASKHIPIMIE-VVKILEEKKITYFSNGNVYFDTSCFKNKTDFVLWFTNGYPSWHLECAAMNLEYFKDALD--IHLGGVDHINEIAIAECFLNK-------------KWCDVFVHGEFLKMSKSRGNFITVKDLEDQFSPLDFRYLCLTSHYRNQLKFSLDNL--QASKIARENLINKLSYFYESLDPVDLNTLNKDLKNFGFSVEKSFDLNVAQGLALLWEIIKSDNLSFVSKLRLAFIFDEIMSLNLREEILKNLQNHDVVIDENMKALIEKRADEIRDFFAKKGFVLVDT. 486
17 -13.3001irx_A mol:protein length:523 lysyl-tRNA synthetase  ali model follow..  13  4..................................................................................................WADYIADKIIRERGEKEKYVVESG---------ITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHIHMWDDYDRKVPRNVPQEWKDYLGMPISEVPDPWGCHES----------------------------------AEHFMRKFEEEVEKLGIEVD-LLYASELYKRGEYSEEIRLFEKRDKIMEDGGWKVKYKCPEGHEGWVDIRSGNVKLRW---RVDWPMRWSHFGVD--FEPAGKDHSSYDTGKEIIKEVYGKEAPL---LMYEFVGI--KGQKGKMSGSKGNVILLSDLYEVLEPGLVRFIYARHRPNKEIKIDLGLGILNLYDE---FEKVERIYFGVEGGKGDDEELRLAVLVQLPHLTEEDIINVLIKQGHIPRDLSKEDVERVKLRINLARNWVKKYAPEDVKFSILEKPPEVEVSEDVREAMNEVAEWLEN............. 459
18 -13.2001f4l_A mol:protein length:551 METHIONYL-TRNA SYNTHETASE  ali model follow..  16  6..........................................................................................................................KKILVTCALPYANGSIHLGH---------------------------------LEHIQADVWVRYQRMRGHEVNF-ADDAHGTPIMLKAQQ-----------------LGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIYDPEKGMFLSPDQYGDNCETPVMRDSEHFFFISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVS--TAELYHFIGVTVNGA--KMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNSRNAGFINKRFDGVLA----------SELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTY........ 491
19 -13.2002d54_A mol:protein length:502 Methionyl-tRNA synthetase  ali model follow..  14  14.....................................................................................................................................VNAEPHLGHAYTTVVADFLARWHRLDGYRTFFLTGTDEHGETVYRAAQAVVQLVLKKVYEAGDIYYGEYEGLYCVSCERFYTEKELVEGLCPIHGRPVERRKEGNYFFRMEKYRPWLQEY-IQENPDLIRPEGYRNEVLAMLAEPIGDLSISRPKSRVPWGIPLPW-DENHVTAVWFDALLNYVSALDYPEGEAYRTFWPHAWHLIGKDHAVFWPTM---LKAAGIPMYR---LNVGGFLLGPDGR--KMSKTLGNVVDPFALLEKYGRDALRYYLLR-----EIPYGQDTPVSEEA-----LRTRYEADLADDLGNLVQRTRAMLFRFAEGRIPEPVAGEELAEGTGLAGRLRPLVRELKFHVALEEAMAYVKALNRYINEKKLFKKEPEEARAVLYRVVEGLRIASILLTPAMPDKMAE.. 462
20 -12.6004qrd_A mol:protein length:547 Methionyl-tRNA synthetase  ali model follow..  16  36.....................................................................................................................................PSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEY------------------------------------------------LDEMIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIYLKEESYFFNISKY---TDRLLEFYDQNPDFIQPDLAVSRTSFNWGVKHVVYVWIDALVNYISALPADIHLMAKEIVRFHSIIWPILLMALD-KDGKMSKSKGNVVDPNILIDRYGLDATRYYLMRELPGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGP-----LHELDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQKDMLG---NVMAHLVENIRYAAVLLRPFL 496
21 -12.0003tqo_A mol:protein length:462 Cysteinyl-tRNA synthetase  ali model follow..  15  1................................................................................................NAMSVKIFNSLTKQKEIFKPIESG---KVKLYVCGMTVYDYMHIGHGRSWIIFDMVVRYLRMRGYEVTFVRNITDIDDKIIKRAGE--------------------NKESPAALAERFIQILHERVLSPDQEPRATQYVPEIIKLIQKLLDNQYAYTGQNGDVFFDVRRFKDYGKLSRHLDELQAGARVEVSDSK---------DPLDFVLWKKEGRPGWHIECSAMSSSILGQPFD--IHGGGLDHENEIAQSEAGEEK--------PFVKLWMHAGLLEINKEKMSKSLGNIISIREALKESDVEVLRYFLLSGHYRNPLSYSKENL--ENGRLALERFYLALRGLPVVNHEKTSSYTDRFYEAMDDDFNTPIAFALLFEMVREINRFRDNNQIEKAAVLAAELKCLGNIFGLLQYSPEQFLQGADQRNEARAKKDWKTADQIRDQLTDLGVAIEDS. 453
22 -11.5002o5r_A mol:protein length:481 Glutamyl-tRNA synthetase 1  ali model follow..  17  4........................................................................................................................DKIMVRVRF-APSPTGFLHVGGARTALFNFLFAR--KEKGKFILR---IEDTDLERSE-YEEKLMESLRWLGLLWD-DVGGDHGPYRQSERVEIYREHAERLVKEG-----KAYYVYAYPEEIEEMREKLLSEGKHYSQEMFEKFDTPERRREYEEKGLRPAVFFKMPRKDYVLNDVVKGE--DFVIMRSNGLPTY---NFACVVDDMLMEITHVIR--GDDHLSNTLRQLALYEAFEKAPPVFA------VSTILGPDGKKLSKRHGATSALVNYLALLGEELISSFSLDRLSPNPAIFDPQKLK-----NGYYLRNMPIEKLAELAKFFEKAGIKIIDEEYFKKVLEKERVEVLSEFPEFEDPAPVEIPEEMKEVFSQLKEELQNVRWTMEEITPVFKKVLKQHGVKPKEFYMTLRRVLTGIIPLLG....... 461
23 -11.5004g6z_A mol:protein length:490 Glutamate-tRNA ligase  ali model follow..  17  18..........................................................................................................................RPVRTRF-APSPTGFIHLGNIRSALYPWAFAR--KMKGTFVLR---IEDTDVE-RSSQEAVDAILEGMAWLGLDYDEGPYYQMQRMDRYREVLAQKGLVYPCYMSTEELDALRE----------RQRAAGEKPRYDGTWRPEPGKVLPEPPAGVAPVPLTGTVAWDDAVKGRVEISNEELDDLVVARPDGTPMY---NFCVVVDDLDMGITHVIR--GDDHVNNTPRQINILRALGG-----EVPVYAHLPTVLNEQGEKMSKRHG-AMSVMGYRDAGYLPEAVLNYLARLGWSHGDFDLEHLGKSPAQNNHYIKEADDARLAGLAKFFAALGIDAGAIEQGPDLVSKDRASTVKEIAENSAMFYRAPAPGADALAQHVTDAVRPALVEFAAALKTVEWTKEAIAAALKAVLG------AHKLKMPQLAMPVRL 452
24 -11.4001li5_A mol:protein length:461 CYSTEINYL-TRNA SYNTHETASE  ali model follow..  15  1...................................................................................................MLKIFNTLTRQKEEFKPIHAG---EVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANE--------------------NGESFVAMVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYDVMFDVPTDPTYGVLSQDLDQLQAGARVDVVDDK---------NPMDFVLWKMAGRPGWHIECSAMNCKQLGNHFD--IHGGGSDHENEIAQSTCAHDG--------QYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAAN--AMASHLRKLSAVLGLLEQEPEAFLQSGQQRLDARKAKDWAAADAARDRLNEMGIVLEDG. 452
25 -11.4004gri_A mol:protein length:512 Glutamate--tRNA ligase  ali model follow..  12  17..........................................................................................................................LSTRVRY-APSPTGLQHIGGIRTALFGKFLLRI------DTDQSRYSPEAENDLYSSLKWLGISFDEGPVV------GGDYAPYVQSQRSAIYKQYAKYLIESG-----HAYYCYCSPERLERIKKIQNINKMPPGYDRHCRNL------NEEVENALIKKIKPPLEGDTSFDDILLGRSPDPVILKSDGLPTY---HLANVVDDYLMKITHVLR--AQEWVSSGPLHVLLYKAFKWKPPIY-------LPMVMGNDGQKLSKRHGSTAAIINYVTLLGNDLEQFFSIEKINKSPAIFDYHKLD-----NSYYIREKKDEDLFNLLLPFQKKGYVSKPSTLEENQKLKLLIPLIKSRIKKLSDALNMTKFFYEDIKSWNLDEFLSRKKTAKEVCSILELIKPILEGFEKRSSEENDKIFYDFAESNGFKLGEIL 463
26 -11.1001rqg_A mol:protein length:722 Methionyl-tRNA synthetase  ali model follow..  13  2..........................................................................................................................VRYMVTSALPYANGPIHAGHLAGAYLADIFVRYLRLKGEDVVFICGTDEHGTPISFRAL-----------------KEGRSPREIVDEFHEQ-------------------------------IKITFQRAKISFDFFGRTELPIHYKLSQEFFLKAYENGHLVKKVTKQAYAEDQKGDQEERAITRD---YVWFEAPIGY---LNIDGQTRVIHFIGKDHAIFWPAFLMAYGKYKDEEVEAEWNLPYDIPAYLTLEGKKFSTSRNWAIWVHEFLDVFPADYLRYYLTTIMPETRSDFSFSDFKVRINEELVNNLGNFVHRALTFVNRYFDGVVPERGELD------ELDREALEEIEKAFKEVGELIMNYRFKDALKRVMSLASFGNRYFDHKQPWKTAKEDKVRTGTTVNISLQIV................ 497
27 -10.9003al0_C mol:protein length:592 Glutamyl-tRNA(Gln) amidotransferase subunit C  ali model follow..  15  19LELSEDQRESLMKDFQEILDYVELLNEVDVEGVEMYTPVEDS------------AKLRKGDPREMRDLIKKNFPEEKDG----HIKVPGIHRGSGSGSGSMFITGAFFDILEVGPKKIRRCFELVRVRF-APSPTGHLHVGGARTALFNWMFAR--KEGGKFILR---IEDTDTERSS-YEQQILESLRWCGLDWDEGPDGDFGPYRQSERLEIYREYAEKLVEDK-----RAYYVVYDKEDPSKELFTTYE----------YPHEYKEKGHPVTIKFKVLPGKTSFEDGYMEFDNSTLE---DFIIMKSNGFPTY---NFAVVVDDHLMRISHVFR--GEDHLSNTPKQLMIYEAFGWEAPVF-------IPLILGSDRTPLSKRHGA-TSVEHFRREGILSRALMNYLALLGWRVEGFDPKDISNKGVIFDYQKLEWVNGKHMRRIDLEDLKREFIEWAKYAGKEIPSVDERYFSETLRICRE-------------VNTLSQLYDIMYPFMNDDYEYEKDYVEKFLKREEAERVLEEAKK.............. 518
28 -10.3001g59_A mol:protein length:468 GLUTAMYL-TRNA SYNTHETASE  ali model follow..  15  2............................................................................................................................VVTRI-APSPTGDPHVGTAYIALFGRFIVRI------DTDRARYVPGAEERILAALKWLGLSYDEGPDV------AAPTGPYRQSERLPLYQKYAEELLKRG-----WAYRAFETPEELEQIRKEKGGYDGRARNIPPEEERARRGEPHVIRLKVPRPGTTEVKDELRGVVVYDNQEIPDVVLLKSDGYPTY---HLANVVDDHLMGVTDVIR--AEEWLVSTPIHVLLYRAFGWEAPRF-------MPLLRNPDKTKISKRKSHT-ALRNYLCLMGFSMPDGREIFTLEEFIQAFTWERVSLGGPVFDLEKLRWMNGKYIREVLSLEEVAERVKPFLREAGLSWESEAYLRRAVELMRPRFD-------------TLKEFPEKARYLFTEDYPVSEKAQRKLEEGLPLLKELYPRLRA............. 403
29 -9.6602cfo_A mol:protein length:492 GLUTAMYL-TRNA SYNTHETASE  ali model follow..  16  1...........................................................................................................................TVRVRL-APSPTGNLHIGTARTAVFNWLYAR--HRGGKFILR---IEDTDRE-RSRPEYTENILEGLQWLGLTWDEGPYFQSDRLDLYRQAIQTKGLAYYCYCTPEELEALRAEQKA------KGQAPRYDNRHRHLTPEEAFEAAGRTPVIRFKIEDDRQIEWQDGRVSWQGADLGG--DMVIARAAGYPLY---NLVVVVDDIAMGITDVIR--GEDHIGNTPKQILLYEALGATPPNFA------TPLILNSTGQKLSKRDGVT-ALANYMTLLGDLAAKHFSFERINKAGARFDWDKLN-----NRQYIQQLEPEEFLAELILWQGAGYAFDEERDRPWLFDQPGLNTLREAIDQGAVFFIPSVTFDSEAMAQLGQPQSA---------TILAYLLEHLPAEPALTVAMGQQLIQQAAKAAGVKKGA.. 438
30 -9.6203pnv_A mol:protein length:505 Glutamyl-tRNA synthetase  ali model follow..  14  8....................................................................................................................GSMTATETVRVRF-CPSPTGTPHVGLVRTALFNWAYARVFRIEDTDAQRD--SEESYLALLDALRWLGLDWDE--GPEVGGPYGPYRQSQRAEIYRDVLARAGEAYHAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTDA-----QRAAYLAEGRQPVVRLRMPDDDLAWNDRGPVTFAAGSVPD----ALTRASGDPLY---TLVNPCDDALMKITHVLR--GEDLLPSTPRQLALHQALIRIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNGLLNYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTVRLRDHLDTHGHHIALDEAAFAAAAELMQTRIVVLGDAWELLKFFN-IDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDAL........... 445
31 -9.3803c8z_A mol:protein length:414 Cysteinyl-tRNA synthetase  ali model follow..  16  37.........................................................................................................................GPTATMYVCGITPYDATHLGHAATYLTFDLVHRLWLDAGHTVQYVQNVTDVDDPLFERAER--------------------DGIDWRTLGDRETQLFREDMAALRVLPPHDYVAATDAIAEVVEMVEKLLASGAAYDVYFRADATAQFGYESERGGDPDRPGKSDQLDALLW-RAERPGEPS------GRGRPGWHVECSAIALTRIGTGLD--IQGGGSDHHEY--SAAHAESVTGERRFARHYVHTGMIGW--DGH--KMSKSRGNLVLVSQLRAQVDPSAIRLGLFSGHYREDRFWSNEVLDEANA-----------------------------------------------RLARWRSATALPEAPDATDVIARVRQYLADDLDT--KALAALDGWCTDALSYGGHDTESPRLVATTVDALLGVD..... 413
32 -9.3702ja2_A mol:protein length:498 GLUTAMYL-TRNA SYNTHETASE  ali model follow..  14  1......................................................................................................................MTATETVRVRF-CPSPTGTPHVGLVRTALFNWAYARVFRIEDTDAQRD--SEESYLALLDALRWLGLDWDE--GPEVGGPYGPYRQSQRAEIYRDVLARLLAAFSTPEEVEARHVAAGRNPKLGYDNFDRHLTD---------AQRAAYLAEGRQPVVRLRMPDDDLAWNDGPVTFAAGSVPD----ALTRASGDPLY---TLVNPCDDALMKITHVLR--GEDLLPSTPRQLALHQALIRIGVAERIPKFAHLPTVLGEGTKKLSKRDPQSNGLLNYLALLGWSIADDHDLFGLDEMVAAFDVADVNSSPARFDQKKADALNAEHIRMLDVGDFTVRLRDHLDTHGHHIALDEAAFAAAAELVQTRIVVLGDAWELLKFFN-IDPKAAAKELGPDGAAVLDAALAALTSVTDWTAPLIEAALKDAL........... 436

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sasin JM, Godzik A, Bujnicki JM. SURF'S UP! - protein classification by surface comparisons. J Biosci. 2007 Jan;32(1):97-100.