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Query: [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit, from COG0516

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRVLast
1 -123.000PF01409.18; SYFA_BACHD/92-341; tRNA synthetases class II core domain (F)  ali   100  1...........................................................................................TIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQF... 250
2 -32.300PF02912.16; SYFA_IDILO/18-86; Aminoacyl tRNA synthetase class II, N-terminal domain  ali   40  1...................DSPTALDEVRVEYMGKKGQLTELLKGLGKLDPSERREAGQKINEAKQQVQTSINARKELLKAAELAQKL................................................................................................................................................................................................................................................................ 69
3 -6.370PF05265.11; Q7DDL1_NEIMB/1-60; Protein of unknown function (DUF723 topsan)  ali   14  1..................................................................................................................................................................................................................................MALTFTQAVSKLTSKFPHLNL----VEFNGVRYPTVIVCPIHGKSGCPKC.................................................................... 59
4 -6.180PF07347.10; T1ER87_HELRO/11-106; NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)  ali   11  1..............................................................................................................TPIIQAVRNWLGQRKLVRTLRFEDYVSPRSAPPPKLPPG-INHKLSANLYYARDVVYDTTKLIASKMEKAETSVSSASSIPKPGSGYD.................................................................................................................................................. 96
5 -6.170PF02964.14; MEMG_METCA/6-166; Methane monooxygenase, hydrolase gamma chain  ali   12  4.........................NDTRDAWVNKIAQLNTLEKAAEMLKQFRMDHTTPFRNSYELDIEAKLEEKVAVLKARAFNE---VDFRHKTAFGEDA------------KSVLDGTVAKMNAAKDKWEAEKIHIGFRQAYKPPIMPVNYFLDGERQLGTRLMELRNLNYYDTPLEELRKQRGVRVV......................................................................................................................................................... 159
6 -6.130PF03006.18; ADRL_CAEEL/195-416; Haemolysin-III related  ali   16  61...........................................................................................................HTLSCHSVNVVKIFCKLDYMLIIGSFIPWIYYGF----------CRREPKITYIAMVSVLGIGAIVVSLWDKFSESRFRPIRAAVFVGMGCSGVIPTIHYIITDGVHSLFADNSFHWLLLMAFLYLLGAGLYATRTPERFFPGKCDIWFQSHQL--------------------TCVVIAAFVH..................................................... 221
7 -5.900PF00684.17; DNAJ_CLOPH/149-213; DnaJ central domain  ali   30  24...................................................................................................................................................................................................................................KGQVTFTQQSLFGMVRNVQ-----------------TCPDCRGTGCPDCYGSG................................................................ 65
8 -5.630PF14357.4; Q21KY3_SACD2/6-87; Domain of unknown function (DUF4404 topsan)  ali   7.....................................KLHDALGDTESTNTDLQAKVSEFERSLKQQLENEAQVNSTSLQDQINQLEAEFAA--------------EHPAERILREIMDVLGRIGV.......................................................................................................................................................................................................................... 82
9 -5.600PF01485.19; Q7S3S6_NEUCR/125-184; IBR domain, a half RING-finger domain  ali   18  1.......................................................................................................................................................................................................................................QAYEDMVEELTTSDPL---YCSNRQCGSFIKGLCPKCFASTCKHCRQA................................................................. 53
10 -5.320PF11945.6; WASH1_XENTR/9-300; WAHD domain of WASH complex  ali   16  13................................LRREEAIHQITDTLQHLQ--------TVSNDIFSRILQRVETNRGQLQRINGRLSLAQAKIERLKGIKKVFSSAKYPAPEHLQEYSSVFAGA-FPVCVNTRGQDEESAEEGLGLPRN--ISSVSSLLLFNTT--VVTRTNPALEGEDEEKLFDAPLSITKREQLERQTAENYFYVPDLGQVPEIDVPYSLP--DLPGVADDLM---YSADLGPGIAPSAPGVPIPELP.................................................................................... 272

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 5 2 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.