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Query: [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRVLast
1 -113.000PF01409.20; SYFA_BACHD/92-341; tRNA synthetases class II core domain (F)  ali follow..  100  1...........................................................................................TIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQF... 250
2 -18.800PF02912.18; SYFA_IDILO/18-86; Aminoacyl tRNA synthetase class II, N-terminal domain  ali follow..  40  1...................DSPTALDEVRVEYMGKKGQLTELLKGLGKLDPSERREAGQKINEAKQQVQTSINARKELLKAAELAQKL................................................................................................................................................................................................................................................................ 69
3 -12.100PF17759.1; A0A0C5VP95_9GAMM/474-682; Phenylalanyl tRNA synthetase beta chain CLM domain  ali follow..  15  1............................................................................................IPVTYPVSGLEMPALKEADISHRVIKNSLVSLGMQEI----------TYSFLDRKTQSLFESELEPVALANPAVMRTSPNLVKTLSYNINRQQERIRLFETGLSFINTNDGLLQN---QKLAGLIYGEEVDFYDLKSIVETVLALAPGKQ--CVFEPGQIEFLHPGQTAFIRC--------------DDQIIGYLGLVHPSIRKTLGLKKG---VFVFELDM.............................. 208
4 -9.090PF00152.20; SYDND_NEIMB/118-567; tRNA synthetases class II (D, K and N)  ali follow..  19  1..................................................................................SENVRLTNRVIDLRRPVMQ---RNLRLRYQVAMGVRRYLDAQGFIDIETP----------MLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAG----RYYQITKCFRDEDLRADRQPEFTQID--LETSFLNEDEIMDITEGMAKQVF-DEEADRYVAVHHPFTAPKEGHEDLMVSDPANCLARAYD-NGWEIGGGSIVQEKVFAALKISPEELDNLKFGFGLDRLVTLMTGAESIRDVIA............ 445
5 -8.260PF13393.6; G2IXI8_PSEUL/10-315; Histidyl-tRNA synthetase  ali follow..  12  13..............................................................................................................ESAKAAMLELFRTAGYELVLPPLIEYADALVSEGDSALDIKTFKLDDHL--GRQLGLRADITPQVARIDAHLNRTGVTRLCYAGSVVHARPSGLMSSREPLQAELYGYAGIEADLEIIELMLATLRQVGVDKLR-------------------------------------LDVGHIAIFR-GLAAAAGLAAEDTRELFGALQSKDIATVRELVAEVAEPYKSAFLALPELYG. 210
6 -8.230PF02091.15; SYGA_PELCD/3-280; Glycyl-tRNA synthetase alpha subunit  ali follow..  11  1.............................................................................................................FQELILALQNYWAKQGCIIQQPYDMEKGAGTF---------------------------------NPATFLRVLGPEPWNVAYVEPSRRPT--DGRYGENPNRLQH-----YYQFQVVMKPSPTNIQELYLDSLKISPSRHDIRFVELGWEVWL----------------DGMEITQFTYFQQVGGIDL-----KPVSAEITYGCERIAMYLQGVDNVYDLWIDGIKYGDVHHQS 190
7 -6.840PF03006.20; ADRL_CAEEL/195-416; Haemolysin-III related  ali follow..  16  61...........................................................................................................HTLSCHSVNVVKIFCKLDYMLIIGSFIPWIYYGF---------YCRREPKITYIAMVSVLGIGAIVVSLWDKFSESRFRPIRAAVFVGMGCSGVIPTIHYIITDGVHSLFADNSFHWLLLMAFLYLLGAGLYATRTPERFFPGKCDIWFQSHQL................................................................................... 209
8 -6.290PF15357.6; PS1C1_HUMAN/4-152; Psoriasis susceptibility 1 candidate 1  ali follow..  11  14.................................................................................................................................QTPALQGPQLLNTDPSSEETRPPHVNPDRLCHMEPANHFWHAGDLQAMISKEFHLAATQDDCRKGRTQEDILVPSSHPELFASVLPMAPEEAARLQQ--SGIHLSASRTLAPTLLYSSPPSHSPFGLSSL..................................................................................... 148
9 -6.130PF04788.12; F6H9T4_VITVI/136-378; Protein of unknown function (DUF620 topsan)  ali follow..  11  1....MYTTGTMKMICCETEISTGKSVKSLGTRSGENGCFVLWQMSPGMWSLELVVGCNKVVAGSNGKIVWRHTPWLGTHAAKGPHRPLRRIIQGLDPKSTASLFAKAQCLGEKRIGEDDCFV-LKVAADRAAVMERNEGPAEV---------IRHVLYGYFSQKSGLLIYLEDSHLTRVQAPGNDTVYWETTIGTSLWD----------YRDVDGVMIAHEGRTIATVFRFGEVSMQHSRTRMEELWVIDDVVFNVPGLSFD.................................................................................. 238
10 -5.980PF15192.6; TM213_HUMAN/29-107; TMEM213 family  ali follow..  13  36........................................................................................................................................................................................................................................................................................................RTGVDEYGWIAAAVGWSLWFLTLILLCVDKLMKLTPDEPKDLQ..... 78

FFAS is supported by the NIH grant R01-GM087218-01
1 2 5 9 6 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24