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Query: [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit, from COG0516

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MREQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFKRVLast
1 -5.480 VFG001153(gi:475773) (hmw1C) glycosyltransferase [HMW1/HMW2 (VF0038)] [Haemophilus influenzae str. 12]  ali   14  289.........................KPVMMVLLEHFNSGHSIYRTHSTSMIAAREKFEGVDNIGREVFDEEISSNNIMERLFFIRKQCETFQPAVFYPIQAVALG--HPATTHSEFIDYVIVE------DDYVGSEDCFSETLLRLPKDALPYVPSALAPQKVDYVLRENPEVVNIGIAATTMKLNPEFLLTLQEIRDKAKVKIHFHFALGQSTGLT----------HPYVKWFIESYLGDDATAHPHAPYHDYLAILRDCDMLLNPFPFGN-----TNGIIDMVTLGLIDEGLFKRLGLTRETYIECALRLAHQERLELRRYIIELQKLFTGDPRPLGKI... 634
2 -5.390 VFG001156(gi:482843) (hmw2C) glycosyltransferase [HMW1/HMW2 (VF0038)] [Haemophilus influenzae str. 12]  ali   13  289.........................KPVMMVLLEHFNSGHSIYRTHSTSMIAAREKFEGVDKIGREVFDEEISSNNIMERLFFIRKQCETFQPAVFYPIQAVALG--HPATTHSEFIDYVIVE------DDYVGSEDCFSETLLRLPKDALPYVPSALAPQKVDYVLRENPEVVNIGIAATTMKLNPEFLLTLQEIRDKAKVKIHFHFALGQSTGLT----------HPYVKWFIESYLGDDATAHPHAPYHDYLAILRDCDMLLNPFPFGN-----TNGIIDMVTLGLIDEGLFKRLGLTRETYIECALRLAHQERLELRRYIIENNGLFTGDPRPLGKI... 634
3 -4.810 VFG001154(gi:482841) (hmw2A) adhesin HMW2A, two-partner secretion (TPS) pathway TpsA exoprotein [HMW1/HMW2 (VF0038)] [Haemophilus influenzae str. 12]  ali   17 1255......TLTTEAGSSITSTKGQVDLLAQNGSIAGSINAANVTLNTTGTLTTVAGSDIKATSGTL------VINAKDAKLNGDASGDSTEVNAVNASGSGSVTA-----------------------ATSSSVNITGDLNTVNGLNI------------------------ISKDGRNTVRLRGKEIEVKYIQPGVASVEEVIEAKR--VLEKVKDLSDEERETLAKLGVSAVRFVEP--NNTITVNTQNEF---TRPSSQVIISCFS-SGNGARVCTN-----VADDG--QP.................................................... 1477
4 -4.470 VFG002276(gi:18309155) (colA) collagenase [kappa-toxin (VF0388)] [Clostridium perfringens str. 13]  ali   285.NTEFYNRIDPYMERLESLCTIGDKLNNDNAWL-----VNNALYYTGRMGK---------FREDPSISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDI-DFNKIKADAREKYLPKTYTFDDGKFVVKAGDKVTEEKIKR-WASKEVKAQFM-----VVQNDKALE------EGNPDDILTVV----IY-NSPEEYKLNRIINGFSGIYIENIGTFFTYE-TLEELFRHEFTHYLQGRYVPGMWGQGEFYQEGVLTWYE-----------EGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGSWDFYNYGFALSNYMYN.... 595
5 -4.300 VFG043369(gi:15644884) (HP0256) involved in motility and cell envelope architecture [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]  ali   12  1MKKFASVLVQLKTLALEKIE--QKLESKRLELQQNEREVLDKQAQLSAFKNPELGGMSLFTQQLKSALRMEIEYYQQESENLNKDLKILEKDY........................................................................................................................................................................................................................................................... 93
6 -4.240 VFG000431(gi:16763123) (tviB) Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase TviB [Vi antigen (VF0101)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]  ali   15  128........EEECVPILARMSGMTFNQDFYVGYSPERGDKKHRLTNIKKITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNI--------------ALVNELAIIFNRLNIDTEAVLRAAGSKWNFHCIGVDPYYLTHKSQGIGYYPEIILAGRRLNDNMGNYVSEQLIKAMIKVLILGFTFKENCPDIRNTRIIDVVKEL................................................................................................................................ 343
7 -4.150 VFG000389(gi:16082727) (lcrE/yopN) type III secretion system gatekeeper YopN [TTSS (VF0140)] [Yersinia pestis CO92]  ali   10  49IADMAEEVTFVFSERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELEQKQN--VSELLSLLSNSPNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGARITPEAYRESQSGVNPLQPLRDTYRDAVMGYQGIYAIWSDLQKRFPNGDIDSV--ILFLQ--KALSADLQSQQSGSGREKLGIVISDLQ-EFGSVSDQVKGFWQFF.......................................................................................................... 282
8 -4.140 VFG000098(gi:15640852) (tcpT) toxin co-regulated pilus biosynthesis protein T [TCP (VF0126)] [Vibrio cholerae O1 biovar El Tor str. N16961]  ali   13  86IEKDIMKIASSATAYGASDIHFIREDRCKIKF-----RVNGTMIDYREILSSEADALMFVLYNVMATTKETTWNRKLP-QDANIILVINEKAYRFHMPLFGEGGKNYHAVVRIIYPSNNFYQDIGYNEADTDAIARILNTSYGLFIVSGTTGSGKSTSLKYKGKGCFVTVEDPVQSSIVADNDDKTKNPFADAVRSAMRRDPDVIMIGEIRDKPGHYCLTTIHAGSVVSVLQRLSG--LGMKADKIASPGFLAGITSQKLIPELCPSCNENGCEACNHSGF............................................................... 411
9 -4.130 VFG002048(gi:82778252) (gspE) general secretion pathway protein E [T2SS (VF0333)] [Shigella dysenteriae Sd197]  ali   13  121....INAMLAEAIKEGASDIHIETFEKSLVIRFRVDGTLHEMLRPGRKLAS-------LLVSRIKVMARLDIAEKRVP-QDGRIALLLGGRAIDVRVSTMPSAWGERVVLRLLDKNQASLAQERGIFLVTGPELNNHSRNILTVEDPIEYMIEGIGQTFARGLRAILRQDPDVVMVEIRDTETAEIAVQASLTGHLVLSTLHTNTAVGTITRLQDMGVEPFLLSSSLTGVMAQRLVRTLCPDCRQAAPATDEETRLLGITDARTVTLYHPQGCPACNHKGFRGRTA-------IHELIVVDAT----------LRDLIHRQAGEMELERYVRQHSAGIRS.... 474
10 -4.110 VFG001151(gi:475771) (hmw1A) adhesin HMW1A, two-partner secretion (TPS) pathway TpsA exoprotein [HMW1/HMW2 (VF0038)] [Haemophilus influenzae str. 12]  ali   14 1291......DLTVGNGAEINATEGAATLTTSSGKLTTEASSHITSAKGQVNLSAQDGSVAGSINAANVTLNTTGTLTTVKGSNINATSGTLVINAKDAELNGAALGNHTVVNATNANGS------SVIATTSSRVNITGDLITINGLNI-----SKNGINTVLLKGVKI--------------------DVKYIQPGIASVDEVIEAKR--ILEKVKDLSDEEREALAKLGVSAVRFIEP--NNTITVDTQNEF---TRPLSRIVISCFS-NSDGATVCVN-----IADNGR....................................................... 1536

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 5 2 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.