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Query: [K] COG1497 Predicted transcriptional regulator, from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKALRKKGELTRFQILSEIAMRQPYVRQKDIADKLGVTVQAVSENIKSLIAEGLVESGSGRSHYKITRRGAEKIKEAAMDLRRYADEVLESMSFYRSVWPAIAWEDLQEGDKVELFMEDGILYARRRRNGEAYAEVLHPARRGEDVALSELGGTIPLQRGKVTIAVLPGISEGGSRNADLERLRELSRGHDRTGIMGTVSRAAANKLNLQVDFEFATPHAALAAAKRGLNVLVLAVGKMSRSITEKLEKEGVEYSVEDLRLTHKELast
1 -100.000[K] COG1497 Predicted transcriptional regulator  ali  100  1MKALRKKGELTRFQILSEIAMRQPYVRQKDIADKLGVTVQAVSENIKSLIAEGLVESGSGRSHYKITRRGAEKIKEAAMDLRRYADEVLESMSFYRSVWPAIAWEDLQEGDKVELFMEDGILYARRRRNGEAYAEVLHPARRGEDVALSELGGTIPLQRGKVTIAVLPGISEGGSRNADLERLRELSRGHDRTGIMGTVSRAAANKLNLQVDFEFATPHAALAAAKRGLNVLVLAVGKMSRSITEKLEKEGVEYSVEDLRLTHKE 265
2 -25.500[K] COG1777 Predicted transcriptional regulators  ali follow..  11  7.NFIAAIENSTRREIIRMLTQFER-SYALELSRSIGLSQQAILKQLEMLERANLVTGFVPSSVGAKRKEPTGFSTLIVDYGRNFLMIQRIPLENDSERVSVSFDEAISKLESIQHHIEE.................................................................................................................................................. 127
3 -21.400[S] COG4860 Uncharacterized protein conserved in archaea  ali follow..  15VSIFHAADSEVKRKLLLDLS--TGWITLPVIEQKYG---KEGRRALLYLDKIKMIEQNGPEKAYHTYYTNVQ................................................................................................................................................................................................. 87
4 -19.800[K] COG0640 Predicted transcriptional regulators  ali follow..  17  1...........................MNEITMQTQADQPKVSSNLAILSEARLVIQMGREKIYRIAPEKFEDMVDWLDSILH...................................................................................................................................................................................... 58
5 -19.600[K] COG4190 Predicted transcriptional regulator  ali follow..  13  60YDDLMDTLTPRVLELIEAIRQEEP-ASINETARVVDRDVKNVHEELSRLAHLGIIFEDGQRKRPVVWFDELV................................................................................................................................................................................................. 132
6 -18.700[K] COG2345 Predicted transcriptional regulator  ali follow..  16  8.NDAHTGDGDTRRKILLIL-LERAPVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAANPRKTYRLTDKGRSIFGHEYDSLAAAALATLREVGGDDAVRQFARKRIETIVEGITPADVTD-----QSIEDTAKSLVEAFSRHGYAATVDATRNGLQLCQHHCPISTVAT................................................................................................ 182
7 -18.600[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  22  178.KVVSALQNATNQRIISEIQNGKC-NTNLALAREIGVSRATISWYVKNLKETGLITRSGRSIIYSINPSYEPLIEKY............................................................................................................................................................................................ 254
8 -17.700[K] COG4189 Predicted transcriptional regulator  ali follow..  12  14FDVLKAAASLIRVQILKLLHEAN-GLNVNEIAQRLALPQSTVSAGVAVLEEAGLLRTESQKICFATCDELIVSFRKPETPAASNYIAVAMPLGLYTQSSVTAPCGICSPEGIIGLWLTSGFVEYQFPNNAKIQGRNVEEIENGKEIGVWTSPGDFGDKRGVFT----PDWWKLSGSQYGMLKTWRITPQGTYVDGTRISDVTLADIDLASHRSIRLRIEVKADAKHPG----LNIFGRGFGNYDQDIV-LRLRTAV......... 309
9 -17.000[S] COG3373 Uncharacterized protein conserved in archaea  ali follow..  18  8.NILRSLNSELRRKVLFYLLSYPYRSYLSEISRAVKSDPSNVKGCLESLIGLGLVIVENGFKYFKINPEIVEEVRNMKNMFSDKKVYTVEI.............................................................................................................................................................................. 112
10 -16.900[K] COG3432 Predicted transcriptional regulator  ali follow..  17  35..........GTMEIMFDILRNEPKCGITRVIYGAGINYVVAQKYLDQLVKVGALNIKNDRKIYEITEKGIEEFIKIRENLYSAKEKVSELLRTDSE........................................................................................................................................................................ 130
11 -16.800[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  13  2........KMKTLFLLIKLAKKEITVTMRELSRELDVSPQTVLRWLEELKEQGYIHKRRKGTLVELTEKGINLLEKLYEEISTALYS.................................................................................................................................................................................. 87
12 -16.300[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  18  11EDLLKAIGKKNEIRIYRLLVEKRRGMRIREIQRELGISERSVRTHVLNLYRRGLLKRQSGWLGYIYTPVSPLEILQKIEHLMKSIEELERDLKNQTRS....................................................................................................................................................................... 113
13 -16.000[K] COG3355 Predicted transcriptional regulator  ali follow..  12  26........SKSDVEVLHILLQNGK-MTTDDLSQKLNVTKASISKALNNLLDKGLIQREKEERKGRPNYIYWVEKERLYRKLEADLEKLAGTVKEALQK....................................................................................................................................................................... 119
14 -15.600[K] COG4742 Predicted transcriptional regulator  ali follow..  23  5.LIDVVFRSQKRRDLLLLL--GEEPRTMEDIKVLLDVSPTAILPQIKRLTDSNLVIQKNGS--YELTDMG-EQVFKKARALVDVLT................................................................................................................................................................................... 84
15 -15.400[K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family)  ali follow..  21  82........SPIEILILHSIRHRDREKKLADICLALDIETHIATYAIRKLEKAGLLTTGAKEKTVKITAKGAEACAHYAQIRERLLVDSTANARPSEETLSELAA................................................................................................................................................................. 180
16 -14.800[K] COG1846 Transcriptional regulators  ali follow..  23  42.........PSEIHTIDAIGTDEG-LLMKELAERLGVTKGAVSQLVDRLEAKALVRRTSRGIQVVLTDKGREAYRAHADMHAAFYEELQQSFTKEEIA....................................................................................................................................................................... 134
17 -14.700[K] COG1510 Predicted transcriptional regulators  ali follow..  35.............RVLGIIYMNRKPMTLSELSEATGMSKTRMSQVVREMIDANIAEKVVRKDLYDVEQDYYQTFISLFANWTKVVSKNKVLYKKLNRELSDLLQR................................................................................................................................................................ 131
18 -13.700[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  10  1...MELSPVFARRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIELNFVQDGRRHND...................................................................................................................................................................................................... 64
19 -13.000[K] COG4738 Predicted transcriptional regulator  ali follow..  14  26VELLRRLNINRPVALTLACLSKGDEISSQRIEMVSGLRQPEVSIAMRYLRENEWVDMREEKKLYKLTVQMETIIDTIEENVIAESKTILQNIERLKS........................................................................................................................................................................ 131
20 -12.900[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  17  10....ELINDYDMLRVLKHF-TIAHVDYAKNITRYTEIPQMRVREYLKRLKDLGLLDYHKHHTYYQINKKAEAVLKEITPK......................................................................................................................................................................................... 103
21 -12.700[K] COG1654 Biotin operon repressor  ali follow..  14  1......MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPE..................................................................................................................................................................................................... 62
22 -12.700[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  18  244....IPLSPELC-EVLDIIRGHKGRITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLGRENILVLVDE.................................................................................................................................................................................................... 309
23 -12.400[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  10  9.EIINDMDTLKRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQENIISP................................................................................................................................................................................................................ 64
24 -11.700[K] COG1695 Predicted transcriptional regulators  ali follow..  16  5...........AIKALVLLSKKPLYQMSKEISTGVQVSHGTLMPMIRKLLQERYIETRGREKVYHLTERGSRFVESLGKIEEDVKQNL................................................................................................................................................................................. 85
25 -11.600[S] COG2469 Uncharacterized conserved protein  ali follow..  23  198........SEVEEQILTMVYTG---VDSVSVESILGVTTEELNKMYDRLVNLGLARVVKIRKEIELTPRGVALVSEIMKKAAR...................................................................................................................................................................................... 269
26 -11.600[K] COG3888 Predicted transcriptional regulator  ali follow..  15  2.........SLRDVLLRELKRARGLIDQFQIEEMMGFSKSTVSEALKDLEEKGIIKRRTIGGKIKHVWLAEYYPYYDEKLLR------IGCLRSTEYVKFVSVAKNYSESKGIDLIVRF-----------DDAISLMNDLSQGLEFALAPIFTEIIYSISNRNSIILGAVASGGSGVYKNVNCNCGKILTSESSSMMILAREFAKTRKISEIAIFKDPRRAIKDYESFAEYIVI............................... 213
27 -10.700[K] COG1321 Mn-dependent transcriptional regulator  ali follow..  24  2VLMHTDRIEEYLETILYLITKNQGPAKTKQIAEELNVSSPSVTEMIKKLHSMGFVEYKPYQG-VELTEKGAEEAVRIKRKHQVLETFLADVL............................................................................................................................................................................. 92
28 -10.600[K] COG1522 Transcriptional regulators  ali follow..  12  7........DKIDRKILEVL-QSNGRLTNLEVAERVNLSPSPCLRRIRRLEESGVIR................................................................................................................................................................................................................. 53
29 -10.600[K] COG1414 Transcriptional regulator  ali follow..  11  21............LDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDR-YSLTLKLFGLAQLHAPRLASFATPFMRELADRSKQANQLA-AQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREMMIAAHVKSRDEVNLDQDFYDRLDQIRERG----------EMMASAQMAGAYNLSAPILGPDGTCVAALTCPYITLVNPSSAPDITQTISLLQKTVRDLSKLV.................. 256
30 -10.500[KG] COG1349 Transcriptional regulators of sugar metabolism  ali follow..  13  1......MKPRQRQAAILEHLQKQGKCSVEELAQYFDTTGTTIRKDLVILENAGTVIRTYGGVVLN-------------EESDPPIDHKTLINTHKKALIAAAAVKYIHDGDSIILDAGSTVLQMVPLLSRFSNITVMTNS---------HIVNALSELDNEQTILMPGGTFRKKSASFAENAFEQFSFDKLFMGTDGIDLNVGVTTFNEVYTVSNAMCNAAADSSKFGRKSPLITDAGIDPAFRQALEAKGIEVIITG....... 253
31 -9.670[K] COG1733 Predicted transcriptional regulators  ali follow..  16  14.MAAEVLCTRWTMVLMRELVA--GSTRFNDLRRGVKMSPTLLSQRLKELELAGIVERKKGIFDYRLTEAG-RDLRPVVEAMGFW..................................................................................................................................................................................... 99
32 -9.580[K] COG1725 Predicted transcriptional regulators  ali follow..  14  9KPIYSQISDWMKKQMITEWKGEDKLPSVREMGVKLAVNPNTVSRAYQELERAGYIYAKRGMGSFVTSDKAL.................................................................................................................................................................................................. 80
33 -9.440[K] COG1378 Predicted transcriptional regulators  ali follow..  11  27IEVLKRLGFRDYEARVYATLATRGEATASEIHRVSGVPRNKVYEVLRSLEDRGMIETIKSSPAVFRAIDPESVLEEYKEQLVSAVDTAIRSIRESEDFSTLHPVWCVRGLAGIKNRAKAMLQRSEE........................................................................................................................................... 152
34 -9.360[J] COG5045 Ribosomal protein S10E  ali follow..  16  3......IPKENRKAIHQALFSQGVLVAKKDFNPEVGVPNLQVIKACQSLDSRGYLKTR-GWFYYTLTNEGVEYLREYLHLPAEVVPATHKRQVRPTAPRAGRPEPRERASA------DAGYRRAEKKDEGAAPSGFAPSFRGG.......................................................................................................................... 139
35 -9.290[S] COG4754 Uncharacterized conserved protein  ali follow..  12  16.............GLLYVMNNFDGKTDLYQLEKEMEVDIDDLMPIVYTASRLGFVSAESGD--IIVTEEGKEYIRASIKRRKEIIREALRNIEPFRTALDLRNFDCETLMENLQRKG.................................................................................................................................................... 118
36 -9.130[R] COG2522 Predicted transcriptional regulator  ali follow..  24  12..AAKNIFPSIRASIAKILVEEYK-MSKYSVAKMLGATPTAVSYYISGKRGEKFVD................................................................................................................................................................................................................. 64
37 -9.100[P] COG0735 Fe2+/Zn2+ uptake regulation proteins  ali follow..  20  7........TKNQSLVMGALAHSDGPMSAYTILDKLR-APLQVYRALDKLLEYGLVHR................................................................................................................................................................................................................ 59
38 -9.040[K] COG1959 Predicted transcriptional regulator  ali follow..  13  1MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTARGKNGGIRLGKPASA................................................................................................................................................................................................. 73
39 -9.030[J] COG4901 Ribosomal protein S25  ali follow..  16  45......LDEKVFQAIAKEVQNMR--ITPYEIASKYGIKMSVAFKVLRNLKERGDLVLVAKGHRTEI....................................................................................................................................................................................................... 103

FFAS is supported by the NIH grant R01-GM087218-01
1 3 1 7 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Topczewski J, Godzik A., Paszewski A. The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases. Microbiology. 2000 Oct;146 ( Pt 10):2695-703.