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Query: [A] KOG0128 RNA-binding protein SART3 (RRM superfamily), from COG1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDVDMESGSDDSGMEDLDEEIQKIKQKMIDDSQSVVLANQLLILLRKNGDFDELDIKRRQFVEWAPLNPLNWKNWIEDFQNRKPEPSVAEVEEMFEKALFDENDVTIWVERAMYAYKVANDKNKKEDFKFCRDVCSKALENLGTRYDSGGHIWLIFLEYEMSYLKNSMNAPDYQRLADQVFALFERALHCPTDQLEDVYVLAEQFCTEFKQHHKLEELKKTYNSTMRQKEQLSKFEELIQQEETKKQGLKQFFDHEKKSGIPSRIKMAHERLVSELDDDEEAWIAYGAWADIELKLPQVAVKVYSRALRHCPYSFVLHQQALLAFERDRRPNEEIDALWERARSNVINSAEEGRSLYRTYAFLLRRRIHLTGSSDYSPMAEVFDEGAALLREWFSMAWDTTADYRQMQAYFYASLMKNMDKCRNIWNDILASGFGRFAGKWIEAVRLERQFGDKENARKYLNKALNSVSDNINEIYMYYVQFEREEGTLAELDLVLEKVNSQVAHRAIRPQKKVSEKPAPAPKSKQDHIQKRTSGGEPIVKKVKGDDGGFKAPLPPSNAKSSSAVSSSNASSTPAPGSFAVQKAAPGTEDARTIFVSNLDFTTTEDEIRQAIEGVASIRFARKANSDLVHRGFAYVVMENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHKDGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQFRKMFMKNLast
1 -224.000[A] KOG0128 RNA-binding protein SART3 (RRM superfamily)  ali  100  1MSDVDMESGSDDSGMEDLDEEIQKIKQKMIDDSQSVVLANQLLILLRKNGDFDELDIKRRQFVEWAPLNPLNWKNWIEDFQNRKPEPSVAEVEEMFEKALFDENDVTIWVERAMYAYKVANDKNKKEDFKFCRDVCSKALENLGTRYDSGGHIWLIFLEYEMSYLKNSMNAPDYQRLADQVFALFERALHCPTDQLEDVYVLAEQFCTEFKQHHKLEELKKTYNSTMRQKEQLSKFEELIQQEETKKQGLKQFFDHEKKSGIPSRIKMAHERLVSELDDDEEAWIAYGAWADIELKLPQVAVKVYSRALRHCPYSFVLHQQALLAFERDRRPNEEIDALWERARSNVINSAEEGRSLYRTYAFLLRRRIHLTGSSDYSPMAEVFDEGAALLREWFSMAWDTTADYRQMQAYFYASLMKNMDKCRNIWNDILASGFGRFAGKWIEAVRLERQFGDKENARKYLNKALNSVSDNINEIYMYYVQFEREEGTLAELDLVLEKVNSQVAHRAIRPQKKVSEKPAPAPKSKQDHIQKRTSGGEPIVKKVKGDDGGFKAPLPPSNAKSSSAVSSSNASSTPAPGSFAVQKAAPGTEDARTIFVSNLDFTTTEDEIRQAIEGVASIRFARKANSDLVHRGFAYVVMENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHKDGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQFRKMFMKN 836
2 -95.000[A] COG5107 Pre-mRNA 3`-end processing (cleavage and polyadenylation) factor  ali follow..  11  1MSSSTTPDDKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLETQESYAKVREVYEQFHNTFPFYSPAWTLQLKGELARDEFETVEKILAQCLSGKLENNDLSLWSTYLDYIRRKNNITGGQEARAVIVKAFQLVMQKCAIFEPKSSSFWNEYLNFLEQWKPF--NKWEEQQRIDMLREFYKKMLCVPFDNLEKMWNRYTQWEQEINSRKFIGELSAEYMKARSLYQEWLNVTNGLKRNIQQLQIWLNWIKWERENKLSQRISYVYKQGIQYMIFSAEMWYDYSMYISEN----SDRQNILYTALLANPDSPSLTFKLSECYELDN-DSESVSNCFDKCTQTLLSQYKKIASDVNSGEDNNTEYEQELLYKNTMKRISGLSAARTVFGKCRKLKRILTHDVYVENAYLEFQNQNDYKTAFKVLELGLKY-FQNDGVYINKYLDFLIFLNKDSQIKTLFETSVEKVQTQLKEIYKKMISYESKFGNLNNVYSLEKRFFERFPQENLIEVFTSRYQIQNSNLIKKLELTYMYNEEEDSYFSSGNGDGHHGSYNMSSSDRKRLMEETGNNGNFSNKKFKRDSE-----PTEVLDLLSVIPKRLDAQKLVNFLNDQVEIPTVESTKS................................................................................................................................................................................................................. 676
3 -68.200[A] KOG1258 mRNA processing protein  ali follow..  13  4...........GDIYIAEETEWDKYNRQINKNPDDFDAWEGLVRASEHKQAINTLRSVYDRFLGKYPLLFGYWKKYADFEFFVA---GAEASEHIYERGIAGIPSVDLWTNYCAFKMETN------GDANEVRELFMQGANMVGLDF-LSHPFWDKYLEFEER-----------QERPDNVFQLLERLIHIPLHQYARYFERFVQVSQSQPRARIYNIHLQIFQKVQLETAKRWTFESEIKRDEAQLVNWRKYLDFEEVEGDFQRICHLYERCLITCALYDEFWFRYARWMSAQPDHLNDVSIIYERASCIFASRPGIRVQYAL-FEESQGNIASAKAIYQSILTQ----LPGNLEAVLGWVGLERRN---APNYDLTNAHAVLRSIIN----EGKCNTGITEVLITEDIKLVWKIEGDIELARNMFLQNAPA-LLDCRHFWISFLRFELEQPHHARVSNVMEMIRNKTRRTIMDLTKLYMEYLCHQSNDPSVLQEYLLIDRDVFGPFSVRESHWKKLDEGQDLKQVSTRLLSTNGHPGISVNEAKIKSGESPYEKYYRLQGVVETVTSGVAANGSS................................................................................................................................................................................................................................................................... 612
4 -67.800[A] KOG1914 mRNA cleavage and polyadenylation factor I complex, subunit RNA14  ali follow..  12  2.................SGLSMRNPERRIETNPFDVDAWNLLLREHQS-RPIDQERDFYESLVKQFPNSGRYWKAYIEHELRS---KNFENVEKLFSRCLVSVLNIDLWKCYIHYVFETKGQR--DQYREEMAKAYDFALEKVGMDV-QAYSIFTEYIAFLKKVPAV--GQYAENQRITAVRKIYQKALATPMHNLELIWNDYCTYEKAINIEKLIAERGKEYQNARRVEKDLQQMTRGLNREFKQVELWKNLIAWEKTNQHARRVVYTYEQSLLCLGYYPDIWYEAAMFLQEASHTLDETISLYERAITGLMKESKLLYFAYADFQEEHKQFEAVKNIYDRLLGI---EHINPTLTYVQLMRFIRRS------EGPNNARLVFKRARE--------DKRTGYQVFVAAALLEYNCMKDKEVAIRVFKLGLKK-YENEPEFGLAYADFLSNLNEDNNTRVVFERILTSSKDKSIRIWDRFLDFESCVGDLASILKVEKRRKTAYEEAQKDQTMNHSMLVIDRYKFMDLMPCSGEQLKLIGYNALKGTESIAGPSFVGSKNVPTHGPQAASAIMGGAGGHADVARYGFPRPQSVAHLMSLLPFIGPFINVELLCN----INNMQLPNVSPKSEDNMLGPMLEQDVKKDMYQLLATTSDPSAVVRSSALSDLKRKRGDSDDEEDYS----HLGAVIGSLGSRDAYKR................................................................................................................................... 728
5 -52.900[R] KOG0118 FOG: RRM domain  ali follow..  16  145....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FRRKKSFGQGKRRMNARTSMAQREDVIRRTVYVSDLDQQVTEEQLAGLFVSCGQVVDCRICGDPNSVLRFAFIEFTDEEGAMTALNLSGTMLGFYPVKVLPSKTAIAPVNPTEREMCARTIYCTNIDKKVTQSDVKIFFESFCGEVYRLRLLGDYQHSTRIAFVEFVMAESAIAAL-NCSGVVLGSLPIRVSPSKTPVRPRSPRHP.................................................................. 356
6 -52.900[A] KOG0105 Alternative splicing factor ASF/SF2 (RRM superfamily)  ali follow..  16  2....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SGWADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNR-HGLVPFAFVRFEDPRDAEDAIYRNGYDYGQCRLRVEFPRTYGGRGGWPRTRRSDFRVLVSGLPPSGSWQDLKDHMREAGDVCYADV------QKDGVGMVEYLRKEDMEYALRKLDDTKFRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFR....................................... 219
7 -52.600[A] KOG4212 RNA-binding protein hnRNP-M  ali follow..  14  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEVGEVTYVELLMDEGKSRGCAVVEFKMEESMKKAAELNKHSLSGRPLKVKEDPDGEHARRAMQKGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERP............................................................... 294
8 -51.600[K] KOG4210 Nuclear localization sequence binding protein  ali follow..  18  16...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DNEEQVKKALLDPTKKRKAEDEIEIDLKSSIPLSKKQKRLLRRGKVTLEELNAKYNIDPKSIEEYKEDAEKKKSGASEKDAQGEESTINTPTGDESGEVVKKKKKDENKYGVWIGNLSFDTTKDDLVRFFIAKTKDNEDEKSRNAMKNKGFCYMFFKNVEQMKAVLELSESHLNGRNMLIKDSENYSGRPDKDSKNPPSRILFVGNLSFDVTDDLLRKHFQHCGDIVKIRMATFESGKCKGFAFIDFKNEEGSTNELKDKSCRKIAGRPLRMEYGEDRSKRQVRKKVENVSRNNSSS........................................................ 337
9 -50.400[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  17  25........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSMKHKGFAFVEYEVPEAAQLALEMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEENRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAA......................................................... 323
10 -50.300[K] KOG0147 Transcriptional coactivator CAPER (RRM superfamily)  ali follow..  18  41...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................STSNSGNETSGSSTIGETSNRSRDRDRYRRRNSRSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHFREKSPVREPVDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSTGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTD..................................................................... 332
11 -49.900[AJ] KOG0123 Polyadenylate-binding protein (RRM superfamily)  ali follow..  16  60.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEMNGMLLNDRKVFVGRFKSRKEREAELGAKAKETNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN................................................. 295
12 -49.300[A] KOG0115 RNA-binding protein p54nrb (RRM superfamily)  ali follow..  13  7...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DNRRSNGRDDSSRVAKAENDRKPGRENRGGDEKRGNSNNAARSGGGGGGNRGGAERGIAPAQQPYDNNGGHRSGGGGGRSGGGGTSFNGAAFTESQLMDEVPKKKFTGRCRLFVGNLPNEVKETELKELFSPHGDIAECYLS-----GKGFAFLRLDTRAHAESAKAIDGRIIHGRQVRVRFAVHG-------------AAIRVKELSPTVSNEMLYHAFSHFGDVERAVHIVDEKGRPTGEGIVEFERKPNCNEAMAAIRDKVFSPKPLICEVLEPRDEDDGLAER.................................................................. 280
13 -49.200[D] KOG1915 Cell cycle control protein (crooked neck)  ali follow..  11  67...........AELSDYRLRRRKEFEDQIRRARLNTQVWVKYADFEMKNKSVNEARNVWDRAVSLLPRVDQLWYKFIHMEEKLG---NIAGARQILERWIHCSPDQQAWLCFIKFELKY-------NEIECARSIYERFVLC-----HPKVSAYIRYAKFEMK-----------HGQVELAMKVFERAKKE-LADDEEAEILFVAFAEFEEQYKFALDQDKEGIEDAIIGKRRCQYEDEVRKNPLNYDSWFDFVRLEETVGNKDRIREIYERAVANVPPPEALWINYAFFAEMVTEDVESTRDVYRACLKLIPHSAKIWLLAAQ-HEIRQLNLTGARQILGNAIGKAPKD-----KIFKKYIEIELQL------RNIDRCRKLYERYLEWSPG--------NCYAWRKYAEFEMSL-AETERTRAIFELAISQALDMPELLWKTYIDFEISEGELERTRALYERLLDRTKH--CKVWVDFAKFEASAAEHKEDEEEEDAIERKKDGIKRAREDRANTYNKDSTPELKEERAMLLEDWLNMETGFGKLGDVRVVQSKLPKKVKKRKLSSREDGCTEYEEYTDYLFPEESETTSLKILEAAHKWKKQKVKAGE................................................................................................................................................................................................................................. 655
14 -48.300[A] KOG0120 Splicing factor U2AF, large subunit (RRM superfamily)  ali follow..  13  5........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DRERDRERRRHRSRSRDRHRERSRDRRHHRNSRRKPSLYWDVPPPGFEHITPMQYKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAAGSNLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQPMPGSTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQSVMLQVPGLSNVVTSGP----------PTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTK. 350
15 -48.200[A] KOG0146 RNA-binding protein ETR-3 (RRM superfamily)  ali follow..  15  6................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ATLANGQADNASLSTNGLGSSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRGMHKGCAFLTYCERESALKAQSLHEQKTMNRPIQVKPADSESRGSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQ.......... 298
16 -48.100[AJ] KOG0148 Apoptosis-promoting RNA-binding protein TIA-1/TIAR (RRM superfamily)  ali follow..  19  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAMNGRKIMGKEVKVNWATTPSSQKKDTSNHF---HVFVGDLSPQITTEDIKAAFAPFGRISDARVVKDMTGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYC.......................................... 207
17 -46.900[A] KOG0145 RNA-binding protein ELAV/HU (RRM superfamily)  ali follow..  16  9...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDTGQSLGYGFVNYIDPKDAEKAINLNGLRLQTKTIKVSYARPSSA-------SIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQ................................................................... 219
18 -46.200[A] KOG0131 Splicing factor 3b, subunit 4  ali follow..  16  10.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GANLLGQHSAERNQDATVYVGGLDAQLSEELLWELFVQAGPVVNVYVPKDTNLHQNYGFIEYRSEEDADYAIKLNMIKLHGKPIRVNKASQDKKSLDV------GANLFIGNLDPDVDEKLLYDTFSAFGVIASNPKIMPDTGNSRGFGFISYDSFEASDAAIESMTGQYLSNRQITVSYAYKKDTKGERHGTPAERLLAATNPTAQKSRPHTL............................................. 222
19 -46.100[A] KOG4206 Spliceosomal protein snRNP-U1A/U2B  ali follow..  16  2........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LTADIPPNQSIYIQNLNERIKKEELKRLFSQFGRILDVVALKT-PKLRGQAWVTFSEVTAAGHAVRMQNFPFYDKPMRLQYAKAKSDCLAKAEGTPPNNILFIQNLPHETTSMMLQLLFEQYPGFKEIRMID----AKPGIAFVEYEDDVQASIAMQPLQGFKITPQPMVISFAKK............................................................................ 232
20 -45.900[A] KOG0144 RNA-binding protein CUGBP1/BRUNO (RRM superfamily)  ali follow..  16  2..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRPQSKGCCFVTFYTRKAALEAQALHNMKVLPGMHHPIQMKPADSEKNN---AVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLN........... 253
21 -45.400[R] KOG0110 RNA-binding protein (RRM superfamily)  ali follow..  19  622.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................APEQVFTKTLSGEPVIPKSEPKPKEEVKPEEKPIVNDAKPDEEDSRAEDADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRFKSLGYGFIQFKKSSVAEHALKLQLTHIDGNPVELKRSDRGAQRRLASQKKQTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRIPKKGEDAHRGFGFVDYMSKAEAKRAFDALSASTLYGRRLVLEWSANDDNQDVEELRKRTAA............................................................. 881
22 -44.600[J] KOG0899 Mitochondrial/chloroplast ribosomal protein S19  ali follow..  17  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MESRHFATAFLASKGFVDILYWVYRFQASSMAF----CTKLGGHWKQGVNVPVSSMLGSLRYMSTKLYIGGLSPGTDEHSLKDAFSSFNGVTEARVMTNKTGRSRGYGFVNFISEDSANSAISAMNGQELNGFNISVNVAKDWPSLPLSLDES................................................................. 152
23 -43.900[R] KOG0226 RNA-binding proteins  ali follow..  10  1.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MANLDDELALFESELAELEQASSNSEEPASSQTHVGYDNATISAGPTT------SESSAATSSAQVIQPSLLAAPPFIPIAATIAVSPFINPALGRLPTMPPVPPSIFMPPQLRAAPIMFPPRVLGIPAPATIEGAPAETPAVNAIPQELLRTQALQSDIDMNFKKQTDPFKKKIKEQQAKKKFVRSGGDENDFRVFCGDLGNEVSDELLAKAFRKYPSFQKAKVVRESTNKSKGYGFVSFRDSEDYVRAMREMDGKYVGNRPIKLRKSAWKERNIDVIKQKRKQKKE........................................................... 298
24 -43.500[A] KOG4211 Splicing factor hnRNP-F and related RNA-binding proteins  ali follow..  19  4.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GTEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGITREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNITLPVDFQGRSTGEAFVQFASQEIAEKAL-KKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR............................................... 217
25 -43.400[A] KOG2047 mRNA splicing factor  ali follow..  11  4............SKDLYPSQEDLLYEEELLRNQFSLKLWWRYLIAKAE-SPFKKRFIIYERALKALPGSYKLWYAYLRERLDIVTHPQYDSLNNTFERGLVTMHMPRIWVMYLQTLTVQ-------QLITRTRRTFDRALCAL--PVTQHDRIWEPYLVFVSQNGIPIETSLRKSERWQESAERLASVLNIKGKTKHKLWLELCELLVHHANVISGLNVDAIIRGGIRKFTD------------EVGMLWTSLADYYIRKNLLEKARDIYEEGMMKVVTVRDFSVIFDVYSRFEESTVAKPALANSVLLRQNPHNVEQWHRRVKIFE---GNAAKQILTYTEAVRTVMKAVGKPHTLWVAFAKLYENH------KDLVNTRVIFDKAVQV------KTVDHLASVWCEWAEMELRH-KNFKGALELMRRATAMKLHRSLRLWSFYVDLEESLGTLESTRAVYEKILDLRIATPQ-IIMNYAFLLEENKYFEDAFKVYERGVKIFKYPHVKDLTKFVKRYGKTKLERARELFEHAVSMAPSDAVRTLYLQYAKLEEDYGLAKRAMKVYEEATKKVPEGQK-SRAAEIFGVPRTREIYEQAIESGLPHKDVKIMCRSLGEIDRARALYKYSSQF--KWHEFEVQHGNEDTY---------REMLRIKRSVSASYSQTHFILPENMMQKDKLLDVEDAKGELKRAGLPEDEMAALERQLLS-------TTTPTEPAKDGGRRVGFVS---------AGVISQSGENEGKPVTGNGEDIELPDESDDESDGDDHVEISQKEVPAAVFGGLARKRDEDGEEAGEDGAAQKLGALERI.... 910
26 -43.400[R] KOG4733 FOG: RRM domain  ali follow..  14  22........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LQAKQSLVPAHPMAPPSPSTTSSNNNSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDTNKCKGYGFVDFDSPAAAQKAVSLKASGVQAQMAKQQEQDP--------------TNLYISNLPLSMDEQELENMLKPFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVIGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKRQNPN........................................................... 235
27 -42.000[A] KOG0106 Alternative splicing factor SRp55/B52/SRp75 (RRM superfamily)  ali follow..  2................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VRVYIGRLPNRASDRDVEHFFRGYGKLSDVIM------KNGFGFVDFQDQRDADDAVDLNGKELCGERVILEFPRRKVGYNEERSGSSTRFRLVIDNLSTRYSWQDIKDHIRKLGIEPTYS---EAHKRNVNQAIVCFTSHDDLRDAMNKLQGEDLNGRKLKCTDETRDRSRSRSPRRRSRSRSPTRSRSPPARRRSPGSDRSDRKSRSASPKKRSDKRARSESKSRSRSGGRRSR........ 254
28 -41.400[R] KOG0125 Ataxin 2-binding protein (RRM superfamily)  ali follow..  14  2............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EKKKMVTQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAG--TGEHNLTLYGSTQAHGEQSSNSPSTNGSLTQTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNE-RGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSP........................................................ 208
29 -41.000[J] KOG0122 Translation initiation factor 3, subunit g (eIF-3g)  ali follow..  15  49...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NDEENKVKITTRTRVRKLASARLNKRAMERRNWPKFGDAANEEAGSHLTMVSTEEILLERPRAPGTKADESKATGDGLSQLGKGGAVLMVCRICHKKGWTSKCPYKDLAAPTDVFIDKPPTGESSTMSAASMRAGADRSAVGSDMRRRNDENSVRVTNLSEDTREPDLMELFHPFGAVTRVYVAIDQTGVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILRVEWATPRPT......................................................................... 294
30 -39.300[AR] KOG1365 RNA-binding protein Fusilli, contains RRM domain  ali follow..  15  226.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSQESRDLALKRHRNFLLSRYIEVYKAGLDEFMHVATGSSTEAMEFVSANAIIVRMRGLPYDCTDAQIRTFFEPLKLTDKILFITRDGRPTGDAFVQFETEEDAQQGLLKHRQVIGQRYIELFKSTAAEANAVEAPEEKKKDCVRLRGLPYEATVQHIVTFLGDFATMVKVHMVYNNQGHPSGEAFIQMINEQAASACAAGVHNNFMSKRYIEVFQASAEELNLHHLVGQQHQVPPPAPLGFMGQLPPQAPQPQQFWSSYPSPPISPIVPGQVTQ-YGIHMSIGVPELVANF... 544
31 -38.800[D] KOG4660 Protein Mei2, essential for commitment to meiosis, and related proteins  ali follow..  14  136...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DVESQDNHAVDASGMQISDRGAANAFVPRKRPNTAGRVSVEHPNGEHPSRTLFVRNINSSVEDSELSALFEPFGEIRSLYT---ACKSRGFVMISYYDIRAAHAAMRLQNTLLRKRTLDIHFSIPKENPSEK---DMNQGTLVIFNVDTTVSNDELLQLFGAYGEIREIRET----PNRRFHRFIEYYDVRDAETALKALNRSEIGGKCIKLELSRPGGARRLSVPSQSQDLERTEVTNFYNQVGSHVANSPPGNWPIGSPVKGSPSHAFTRPHGLGMVRPVNSD........ 411
32 -38.700[A] KOG1190 Polypyrimidine tract-binding protein  ali follow..  14  9..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKG----KNQAFIEMNTEEAANTMVNYTSVTPRGQPIYIQFSNHKELKTDSSPNQARAQAIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTK---NNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFASPYAGAGFPPTFAIPQAAGLSVPNVHG......... 325
33 -37.900[A] KOG4209 Splicing factor RNPS1, SR protein superfamily  ali follow..  17  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MSDNDIIDDDVLNIEDGDDADLSAIELNEIEEEQKKLKAIQNEMVGHMNLNTSSQSNSSLTPEEKAEADAKSVYVGNVDYGATAEEIEQHFHGCGSVSRVTIQCDRSGHPKGFAYVEFTEKEGMQNAL-AMTDSLLRGRQIKVDPKRTNKPGMSTTNRPPFRGRGGRGRGNVIVKY................................................ 183
34 -37.700[A] KOG0117 Heterogeneous nuclear ribonucleoprotein R (RRM superfamily)  ali follow..  13  13.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDNGNNRGYAFVTFSNKVEAKNAIKLNNYEIRNGRLLGVCASV------------DNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQGHGIAVDWAEPEVEVDEDTMSSVKI---VRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDG 293
35 -37.400[K] KOG1548 Transcription elongation factor TAT-SF1  ali follow..  16  56..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VTAEATEGKESSNGEDRHTKRLYESTSAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTDGTPKGDALIVFFRSESVELAEQFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKNKIVVLKHI-LIDLKDDITEEAEKCGRVTNVVL----DKEPDGVVTVRFSNNEEAEACVRLMQGRYFDGRVVEASIYDGKVRFQKSGKHTLDDEEDEEK........................................................ 354
36 -36.300[R] KOG2396 HAT (Half-A-TPR) repeat-containing protein  ali follow..  11  16LDDLERREIFTRAEIAEIVKQRRKFEYRLKRPSPLKEDFIAYIDYEVKLDELARIVEIYRLATMRYKGDINLWFRYLE----FCKQKRHGRMKKALAQAIRFHPVAGVWIYAASW------EFDRNLNVTAARALMLNGLRVC----SNSEDLWVEYLRMELTFLNKLKARKVKEKGSNVLQTIYSGAVEAIPSSFDEILEATDLAHSDEMRNTILSDLKRDFCNEPEYWKAIQVFEEGLQTVTSS-SMFEIYINFSLSNPIISHIINVYQKADETGCLTEELADEYVSLYLKLEKTHEAQKLAEKLCSEKFAGSAKLWLSRVSISSPSKADFQTVFELLSNALRKV--PISESESLWLMAFNFFAHQRTYLDKKGAHSARKIYKRFLAL---------GPSLVLYKGCIEIETNLISGLSNARKLYDSAVAS-YGQDVELWKNYYSLETKLGTSETANGVYWRARKTLNESADFIV....................................................................................................................................................................................................................................................................................................................................................................... 648
37 -36.100[A] KOG4205 RNA-binding protein musashi/mRNA cleavage and polyadenylation factor I complex, subunit HRP1  ali follow..  15  6.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................STGATAVATLRETSPPVDGHEEARLNADSDDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPKRARGFGFITFVDPSSVDKVLNNREHELDGKKIDPKVAFPKRTQA---KLVTKTKKVFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDKTQRHRGFGFVTFDSDEVADKVCEI-HFHEINGKMVECKKAQPKEVMLPVQLNKSRAAAA........................................................... 228
38 -36.000[R] KOG4307 RNA binding protein RBM12/SWAN  ali follow..  11  440...................................................................................................................................................................................................................................................................................................................................................................................................................................................AAVEKFYIELTRLPTDLLRPAALEAFIHPTAPLTLSSVKTVFGTIIRLDSIADYATMMRRNGEQGIKIQQSDKKSFDTAIDGIPIPSVSMVPSKEQRSHEDDDKKSRRSRWENTSPIRSPRRSPLRRDNRDRSRSRSPPRRRRRSRSPRRREEHTDPTRVQVTNVPFRMKDEELLEWFSEVRPAKLTRTFYSDGNASDRWVAEFSSESLMKRSFG-IRTLCTGRTLRLRYIDNAKADEILKIEDVYGEGLSCNGFPKDVTLEDVVEFFNDYE--NSIRIRRGDDGVMTGECMLACQNQENARRASMDLDGQKLRNSVISVRI............................................................................... 947
39 -35.500[A] KOG0121 Nuclear cap-binding protein complex, subunit CBP20 (RRM superfamily)  ali follow..  14  13...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QHFKGSRSEQERSLRDSCTLYVGNLSFYTTEEQIHELFSRCGDVRVIVMGLDKKTPCGFCFVEYYVRSEAEAAMRVNGTRLDDRLIRVDWDAGFVEGR-------QYGRGKTGGQVRDEYRTDYDAGRGGYGKLLSQKIAPNTDNR................................................................................................................... 154
40 -34.000[A] KOG0108 mRNA cleavage and polyadenylation factor I complex, subunit RNA15  ali follow..  14  2.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SMTAGNVVFVGNIPYDVSEQQMTEIFNQVGPVKTFKLVLDPTGSGKGYGFCEFFDSETTAMAVRKLNNSELGPRKIRVEFPSNDPRRNQSYEYTERTDRYMEQQNAHESSYNSRFIPPVLHSTSSLPASQGGGMPSPAIYSSSMATNLN.......... 151
41 -34.000[A] KOG4207 Predicted splicing factor, SR protein superfamily  ali follow..  19  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPLEPTKAPRGFAFVRFHDRSDAQDAEAAMDGAVLDERELRVRMARYGRRDLPRSSQEEPRGRSWGGRYGRRSGSPRGRHRSQSRGPSYSRSRSRSHYGGSRYSLSIYRRSRYSR........ 160
42 -33.600[R] KOG0130 RNA-binding protein RBM8/Tsunagi (RRM superfamily)  ali follow..  18  17...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EDGDQGIVRLKEKAKHRKGRGFGSDSNTREAIHSYERQRSVEGWILFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRTGFSKGYALVEYETHKQALAAKEALNGAEIMGQTIQVDWCFVKGPKRVKKSEKRRR.............................................................. 165
43 -32.000[R] KOG1124 FOG: TPR repeat  ali follow..  12  141.....EPERSESSSSSSAAAAARAQERPLAVNL---DLSLYKAKVLARNFRYKDAEKILEKCIAYWPEDGRPYVALGKILSKQS---KLAEARILYEKGCQSTQNSYIWQCWAVLENRL-------GNVRRARELFDAATVA-----KKHVAAWHGWANLEIK-----------QGNISKARNLLAKGLKF---RNEYIYQTLALLEAKAGR----------YEQARYL------FKQATICNSRSCASWLAWAQLEIQQERYPAARKLFEKAVQASPKNRFAWHVWGVFEAGVGNV-ERGRKLLKIGHALNPRDPVLLQS-LGLLEYKHSSANLARALLRRASELDPRHQP----VWIAWGWMEWKE------GNTTTARELYQRALS-----IDANTESASRCLQAWGVLEQR-AGNLSAARRLFRSSLN--NSQSYVTWMTWAQLEEDQGDTERAEEIRNLYFQQRTEVVDDASWVTGFLDIIDPALDTVKRLLN.................................................................................................................................................................................................................................................................................................................................................. 571
44 -31.700[R] KOG0114 Predicted RNA-binding protein (RRM superfamily)  ali follow..  15  2.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NKRNHIRLPPEVNRLLYVRNLPYKITSDEMYDIFGKFGAIRQIRVG--NTPETRGTAFVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYQSNKAFKRVDMDKKQEELNNIKAKYNLKTPEA.............................................. 120
45 -31.500[A] KOG0495 HAT repeat protein  ali follow..  13  269.....SMIPTYGGDINDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKVQMARNLIMRGCEMNIQSEDLWLEAAR--------QPPDTAKAVIAQAARHIPSVRIWIKAADL----------ESETKAKRRVFRKALEHI----PNSVRLWKAAVELENQIWTTAAKLEEANGNIHMVEKIIDRSLTSTVNGVEINRDQWFQEAIEAEKSGAVNCCQSIVKAVIGIGCARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDV-PAARGILSLAFQANPNSEDIWLAAVK-LESENSEYERARRLLAKARGSAPTKFDEALRLLEEAVEWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSI--------PLWILSANLEERK-GVLTKARSILERGRLR-NPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNAGE-LWAEAIFMETKPQRKTKSVDALKKCEHDPHVLLAVSKLFWSEHKFSKCRDWFNRTVKIDPDLGDAWAYFYKFELLHGTEAQQQEVLDRCISAEPTHGESWCRVSKNIQNWQFKTPEVLRAVVRELSIPI........................................................................................................................................................................................................................................ 913
46 -31.000[R] KOG0154 RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains  ali follow..  139...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RRRTSRDRRDDRSSRRRRDRSHSRSRSPPSSANGSSHWSSSNRHSRRRRSRSYSRERDRNSRRDDRRSNLSNNDRYSDWNPGVPSNKLAILNMPNDVDNTKITLSLGKCGYLQDVRTMKNTKQIRTFAFVEFSNRETAEQWMTDYEGWLDGRTLAVEYAKGDPAAGSGNKGDTPCDTLLIRGLPDGINNSLIFDSLGALVCLSSISMI--KLSESKRFAYLQMKSADEAKMLLNLTYKIRIKDKDVQVSWCRDSMSKLIQQQMTMLTAGPGKNS....................................................... 461
47 -30.800[R] KOG4454 RNA binding protein (RRM superfamily)  ali follow..  15  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EIKPTPSPPEERTIYVANFSEEVDEELLEELFIQAGPVVKVILRDV-RDSNAKFALVEFEDELSVLFAIELMNGVRLFNQELQVKPRNGTNQEELYKRKKGEIEERVRSVAAPDRDGRRDSYRDDRNRNRNGNNRDSWQQQQPPRHHRQYDPLPPP......... 156
48 -30.700[R] COG0724 RNA-binding proteins (RRM domain)  ali follow..  23  124.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KTILSELSALEDPATNEGGVEAASEEKAGQVGGASRRAGARDPSSDAYRDSRERDDMCTLKIMQVNENADENSLRELLFPFAPIPRVSVVRNKTGKSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPKVKE........................................................................ 274
49 -30.200[A] KOG0107 Alternative splicing factor SRp20/9G8 (RRM superfamily)  ali follow..  16  2..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SRVYVGNLDPRVTERELEDEFRSFGVIRSVWVARR----PPGYAFLDFEDSRDARDAIREVDGKNGWRVEQSHNRGGGGGRGGGRGGGDGGRGRGGSDLKCYECGESGHFARECRSRGGSGGRRRSRSRSRSPPRYRKSPTYGGRR........ 143
50 -29.300[AR] KOG0109 RNA-binding protein LARK, contains RRM and retroviral-type Zn-finger domains  ali follow..  11  259.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SVRDKEDQWTVSVQRQLVYRPSTEAGHNNKELPPPLPPRGACPDDEAVHQKPAPGHRAGDPLSFQAVGKVLECDII------KNYGFVHIEDKTAAEDTIHLHHYKLHGVNINVEASKNKSK---------ASTKLHVGNISPTCTNQELQAKFEKYGPVIECDIV-------KDYVLIHFIHMECCPQARLRTAPGMGDQCGCYQCKKEGHWSKECPVDRTGRVADFTEQ........................................................ 469
51 -28.800[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  12  234..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TCQQNLLSHANGRKHRENVELFDATQQQQLEKTTVDKKDTTVNASDGNSEQKKVDLLVSSGVANGYSQAHKKRKLETCDETWKREVVQAEEAKGGGEQKSESKKAKKQDKEKKRKKDKTKSDSDFEHDKEDIKQLLVAYSKEELVNLIYKTAEKGSRLISAILESADRDIAQRNIFVRGFGWDTTQENLKTAFESYGEIEECSVVMDKTGRGKGYGFVMFKTRKGAREALKRPEK-RMYNRIVVCNLASEKPGKAGKEQDMAE............................................................... 498
52 -28.800[R] KOG0149 Predicted RNA-binding protein SEB4 (RRM superfamily)  ali follow..  12  2..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AYQPVPGSGFHYLNSPFGDTTFTKVFVGGLAWETQSETLRQHFEQYGEILEAVVIADKGRSKGYGFVTFRDPEAARRACADPTPIIDGRRANCNLASLGRPRP-----PLPYAVIPNMPDLLPRTLEMCRVLEVHLLEIIRISNHFHITSKELSILMVTAYGPEYMYSQSQGLYS-PYMGQQYLQVYGVPGAVNSPVYSVPGSHILQLGGPTVSTMTTSSMPALQAPYPSGIPGPAPVQSHIIVHSPQFMQSTASDQTTR...... 279
53 -28.700[J] KOG0129 Predicted RNA-binding protein (RRM superfamily)  ali follow..  15  419............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EDGFLDDGRGDQPLHSGLGSPHCFSHQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAYFPPKGYAFLLFQDESSVQALIDACIEEDGKLYLCVSSPTIKDKPMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRYGGVCYAGIDTDPEKYPKGAGRVAFSNQQSYIAAISA-RFVQLQHGEIDKRVEVKPYVLDDQLCDECQGARCGGKFAP..................................................... 664
54 -27.400[R] KOG4208 Nucleolar RNA-binding protein NIFK  ali follow..  26  2.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AAFSRSAGPILSLNP-QEDAELQKEVAQCDTVTRFRLSRKKTGNSKGYAFVEFESEDVAKIVTETMNSYLFGERLLECHFMPPEKKMES...................................................................... 90
55 -27.200[A] KOG0533 RRM motif-containing protein  ali follow..  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VKATNVDLSLEDI--ISKTRKTTGSIQKKS------GGARRGNTRPTGLPRRSGGSGGWKDLDAVQNHGISSRGNDSKVIRVNISNLAPTVISSDLEELFGDYR-LSSVSVNFNEHGDSLGTGDISLTK-RDAERLVQKFSGVALDGKIMKFAVIDSSNMAGRVDFGNRSRSSPGRSSRGFQSGPRRNNGKPEDFLKRGGAGRGGFRKGGRGGARDAKPKKTEAELDAEL... 231
56 -26.900[R] KOG1457 RNA binding protein (contains RRM repeats)  ali follow..  12  12.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GSTGTGSGAGSGGALEEEPQNLGFRGQSCELEAGIHRGIIQWDHPPFVHELKTRPGVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLT---ARQPVGFVIFDSRAGAEAAKNALNGIRFDPENLRLEFAKANTKMAKSKLMATPNPSNAWAPYPLYTTELTPAISHAAFTYPTATAAAAALHAQRRHIRQCTPTCR........... 235
57 -25.400[R] KOG0126 Predicted RNA-binding protein (RRM superfamily)  ali follow..  13  8..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KLINELNEREVQLGVADKVSWH----SEYKDSAWIFLGGLPYELTEGDIICVFSQYGEIVNINLVRDKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYRAPKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTKKHKKDKKEKKKKKKEKEKADREVQAE........ 182
58 -24.700[R] COG5191 Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat  ali follow..  16LEDLLEKNIFNRDEINNIIKTRRVFEEKLARRQVKLNDFLSYIQYEINLETLRKVLFLFLRATNKFFGDVTLWLDYIHYAQKIK---AVNIVGKICVAALQKHPNAELWVVACDH------EFSINANVSAARALMNRALRL-----QENPVIWAAYFRLELSYMTKLFARSQNGVSEDTIGSLSSDTIQLPMVSMEEFLGSSSSEVRKNDSDLNISDDIGNISSKEQQTQKFANVSRKNLSLQNYVGFFVSVLDALFECFDVPVVQYMYQENIIGICNEHHRWCFLEIFIKLRGAYPSNDSGISGKGIFGLKKNDPRITSMVLTDPGFVDDLQAIVEKYQSISSDFQIPFKTKKIFYSFFVKTLHAI------SSSSAAESSIALALH-----------------------------------MLVINAFQSMEKLKILTFDDSLQEIYKEAQIQSGTFMSNATLS................................................................................................................................................................................................................................................................................................................................................................................. 488
59 -23.100[R] KOG1995 Conserved Zn-finger protein  ali follow..  16  263.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TEKVKQCDADCDDNCDNARIYISNLPPDVTTDELKDLFGGIGQVGNIKIYTDEKGNYKGDACLAYEDPSAAHSAGGFFNNYEMRGNKISVTMAEKSAPRAPTFDQSFIILVGNMSFCNAKFMFLVSE---RGGGRGGGGGGYGGGGGDRRRDNYSSGPDRNHH-RKLIFN. 484
60 -22.100[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  12  187...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PDDPLCEQNIKDRYYGRNDPVAEKIMKRAASLPTLEPPEDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVPR-----QQCAFVQYTKRNAAELAAERTNKLVIQGRKVSIKWAHSQAKQGTAAKTDRRFDLAGIPPPSAKPNDYFNLRQEQINVMPAGMKLHQLPSNLVPASAYQMYGQPT.......... 369
61 -21.000[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  11  2............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ADVVLDLYAEDLDKDFAGQAQDEFGGDGVDLYDDIGGPTESAASG----GGGGTPSADGAAGPGSGEPGERNSGGPNGVYHQSSGSLTPTMNRRYQLYVGNLTWWTTDQDIANSLRDIGDLQEVKFFENRNGQSKGFSVISLGSESSLRAVLDQLPKKEMHGQAPVVTYPSKQALTQFESLQKTRPVPPPQQNGPPRGPAPPSMGGGPMPTGHPGGPQGGGPPGHPPRGMNSIMQPGQ.......... 239
62 -21.000[A] KOG1996 mRNA splicing factor  ali follow..  106.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFSRRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEPDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGL---KHEQGLSTALSVEKTSKRGGKIAQDASKKSDSNPLTEILKCPTKVVLLRNMAGEVDEDETKEECEKYGKVGKCVIFEIPGAPDDEAVFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQ................................................................. 404
63 -20.800[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  16  331.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TQPGSFRGAPRGRGNIRGRGGFARGGFTGAINRDNCTLQVAKIPPENTIAKLNEHFATFGTVDNIQVRYNGEIDS--ALVTYASKFDAGKAYKSPTPVLNNRFIKVFWHNPGGEGSENATGKPSSSVVIVRGVTDE-LVTDLMAHMEKFGEVFDHSVKADDDGLIT--AVFPFRKTGDALKAMA--DGKVLNGVDLEMELKTERIEEIPSTDTNMSADQLLAAIPSNLESDEEDDL........................................... 716
64 -20.100[B] KOG1156 N-terminal acetyltransferase  ali follow..  11  91............RSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPD----YEYSELLLYQNQVLREAGLYREALEHLCTYEKQI----CDKLAVEETKGELLLQL-----------CRLEDAADVYRGLQER-PANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPLWVQYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAG-NIKEAARWMDEAQALDTADRFINSKCAKYML----------KANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEALKKCHEIER--------HFIEITDDQFDFHTYCMRKITLRSYVD------------LLKLEDVLRQHPFYFKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQKKAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEK------------------KVETPLEEAIKFLTPL--KNLVKNKIETHLFAFEIYFRKEKFLLMLQS-------RAFAIDSSHPNTAVCESKDLSDTVRTVLKQEMNRLFGATNPKNFNETF---RNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTLDE-SLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKL---------PYALAFMPPGYEEDMKITVNGDSSAEAEELANE......... 865
65 -20.100[T] KOG0116 RasGAP SH3 binding protein rasputin, contains NTF2 and RRM domains  ali follow..  11  16..................................................................................................................................................................................................................................................................................................................................................................................................GNSFVEKYYNLLYKSPSQVHQFYLDDSVGEMVSVKSLKAINEQIMS----------FDYEISKIQILTADSQASYMNGVVTLVTGLLTVKEGQRMRFSQSF--LVPLNGSYFVLNDVFRYVADEIVEPEANKKEVEEVIPQVVQPTEQVDEVAEPVTIPTQQPEAKQTTENTVKKPERAVANGHPKTQEDNVVNDKSNGVDAPKKSFAHIVQDLAQNGATFN-------------------------------AKASPAKPKSKPVTKPSAARESKAPAPVSEHSSAATIDQQAEGYTIFVANLLMDATPEQLNETFKGFGAITKDGIVRSYRLKGNCFGFVTFASAEAVKLVLQAESAIRIGNRRVSIEEKRGNNDNGRPAMRNGGYRNDNGYRNDGYRPRGNGSNGGRGYGRNGSERRGESRNGEAHNGDGKVHQNGTVEASR..... 428
66 -19.200[K] KOG4661 Hsp27-ERE-TATA-binding protein/Scaffold attachment factor (SAF-B)  ali follow..  10  231...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSPEDDSDTKRLSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNRSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRKDDAKKGDDGSGEKSKDQDDQKPGPSERSRATKS..... 555
67 -18.700[T] KOG4162 Predicted calmodulin-binding protein  ali follow..  62.ENALASDSNFGRAKSGLAEARRFLHLALGESGQKLDAYLLLAKLCFACGEYEQSLDNFVKAELNTLAEKELTLRSLK-SSKFKKAEKDTEMISCFERAS------DLGLLYLQEYDLVSGSSGSSNNSTRMGAILETALQRAPIVLIKTEKLQEAVERY-RIMLNAIETRATQSLRLTLARQLYSPPFTGKSGGGTLRGGSSKKLWKAARQQFNPRNQQEEVILLLLIAEALAVRDTVLSQSPEFRQARQHAMGNVTRWGLVQLLNESFEKALKFSFGEQHVWRQYGLSLMAAEK-HSHALRVLQESMKLTPSDPLPCLLASRLCYESLETVKQGLDYAQQALKREVKGLRSRSQLFVG-QLAIQSNLKSERDACHKLALDALERAVQF---------DGNDHLAEYYLSLQYALLGQLAEALVHIRFALA--RMEHAPCLHLFALLLTSSRRPREALGVVEDALHEFPDN----LQLLHVKAHLQLHLEDAETALGTVQHMLAVWRDVYEAQLAGEEEKHSDTKSGVHLAHSSQMSDKDSNSVYAASLAAVSRVEQALSEAASSLSS----------TQRPGPRRPWMLQIEIWLLLADVYLRIDQPNEALNCIHEASQIYPLSHQ--MRGQVHVYLEQWFDAKQCFL--------NAVAANPNHTEA----------------LRALG--LVLGEPRLAEKMLKDAAKLDPSCPKIWFALGKVMEILGDFHASADCFA---------TSLQLEPSCP............................................................................ 849
68 -18.200[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  11  13..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RKHRSRNTEKKKKPRRRERRMKQLVCIKSPWNRFKGIMLQLRLLLEVTINPNDNKLKPDSQGMFPPFVKDQRIRDEERSKEMEKGKTRNIDHFVEELKREQEIRERRNQDRENDELPDYFDPSGRLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMEEEKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELKIGWGKVVFLPSQALPAPPPGHMAIRSKEGCNLIFSVTSGPPMNSVPNQNSELVLTPNVPDITVISPEDEDGGCAFEQAIME. 341
69 -17.800[K] KOG3152 TBP-binding protein, activator of basal transcription (contains rrm motif)  ali follow..  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MQSEESHELTDGISEEKESKETMKSQKADRKKKKLKEKLLKEASKACYLSRIPPHMDHVRLRHILAQYGELGRIYLAPEFRGQRFSEGWVEFAKKSVAKRVADMLNGEQIGGKKKSAKREKDFYLSKIEKSRAMTEIDARMEKKRKIQEESGSNAEAAPVFPPRAIFQFRQKKSIENETSQSKPGLSTDFLASVFGGS 266
70 -17.700[K] KOG2068 MOT2 transcription factor  ali follow..  10  2.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SDYGEKTCPLCAEEMD--LTDQQLKPCKCGYQ--HHIMDMAEKDQSEGYDKEKIVGMTVDQERLASEGNMDRKKIQKSKPKSSDGRKPLTSVRVVQRNLVYIVGLPLNLADEDLKEYFGQYGKVLKVSMSRTQFPNNTCSVYITYGKEEEAIRCIQSVHGFILDGKALKACFGTTKTKDEIISAHTRVQQITGATNTMQYRSGSMLPPPLDAYTSDSSTGNPIAKVPSSTSVSAPKSSPPSGS........ 292
71 -17.200[A] KOG2202 U2 snRNP splicing factor, small subunit, and related proteins  ali follow..  12  43.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SPTLLLSNMHFEDFFEDLFEELGKFGEIESLNICDNLADHMIGNVYVQFKEEDQAAAALQALQGRFYSGRPIIADFSPVTDFREATCRQYEENNCNRGGYCNFMHVKLVSRELRRKLFGRYRRSYRRGSRSRSRSRSISPRNKRDNDRRD..... 217
72 -17.200[DO] KOG1174 Anaphase-promoting complex (APC), subunit 7  ali follow..  11  12....AAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIDKDAIAILDGIPSRQRTPKINMMLANLYKKAGRERPSVTSYKEVLRQCPLALDAILGLLSLSVK-GAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKK-DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDLYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKR-YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGR-VQEAIIHFREAIRLAPCRLDCYEGLIECYLA----------SNSIREAMVMANNVYKTLGA--------NAQTLTLLATVCLEDPVTQEKAKTLLDKALTQ-RPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVRILGDFLVAVNEYQEAMDQYSIALS.................................................................................................................................................................................................................................................................................................................................................. 503
73 -16.900[A] KOG4213 RNA-binding protein La  ali follow..  15  2....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AENGDNEKMAALEAKICHQIEYYFGDFNLRDKF----------LKEQIKLDEGW-MIKFNDFNVIVEALSKSKAELDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPG-QKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQK............................................... 216
74 -16.800[TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1  ali follow..  10  5....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DLQDLPSATIACHLDPRVFVAKFESLFRTYDKDITFQYF-----KSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQ-SPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPS........... 155
75 -15.800[R] KOG1129 TPR repeat-containing protein  ali follow..  10  5.............SDSTYVDELENEDMGLAEDQNVIAPNARPGTSFARPKTSAKGVNPILRPT----TNAGRPLSGVVRPQSSFKSGSMDQAVRTARTAKTARAVSSTSARNMRLGTASMAAGADGEFVNLARLNIDKYAADPQVNRQLFEYVFYYLNDIRVAHQIAGTASKAAGFEKNQLAKCYLRL------MLQDATKQLQSSLEQKKLIETFALLSKAYNRVDQPMAALKTYSAGLEVFPENVTMLTGMARVQEALGEYDESVKLYKRVLDAESNNIEAIACVATTYYYGGKP-ELAMRYYRRILQMGVSSPELFLNIGLCCMAAQQ-FDFALSSILRAQSTMTDDVAADV--------WYNIGQILVDIGDLVSAARSFRIALSHDPDHSESLVN-----------ILKHREGKIDEARSLYSSATSK-NPYMFEGNYNLGLVSFTQGKYHECRELIEKALAAFPEHEHCKKIL--------NHLKPLYESI................................................................................................................................................................................................................................................................................................................................................... 458

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Rychlewski L, Zhang B, Godzik A. Fold predictions for bacterial genomes. J Struct Biol. 2001 May-Jun;134(2-3):219-31. Review.