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Query: [E] COG0014 Gamma-glutamyl phosphate reductase, from COG1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVVVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIAYSFLPALSKQMAESGVTLHADASALAQLQTGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRALast
1 -70.100IDP02108 gene: aldB; aldehyde dehydrogenase B [Salmonella typhimurium LT2] STM3680 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  16  64.IDLALDAAHKAKDKWAHTSVQDRAAILFKIADRMEQNLELLATAETWDNGKPIRETSA-----------ADVPLAIDHFRYFASCIRAQEGGISE--VDSETVAYHFHEPLGVVGQIIPWNFPLLMWKMAPALAAGNCVVLKPARLTPLSVLLLMEIIGDL-----LPPGVVNVVNGAGGE-IGEYLATSKRIAKVAFTGSTEVGQQIMQYAIPVTLELGGKSPNIFFADDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESIRSGNPLDSGTGYYLEPTILFGKN-NMRVFQEEIFGPVLAVTTFKTMEEALEIANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRET----HKMMLEHYQQTKCLLVSYSD... 506
2 -68.300IDP01015 gene: gabD; succinate-semialdehyde dehydrogenase I STM2791 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  50.TRDAINAANRALPAWRALTAKERANILRRWFNLMMEHQDDLARLMTLEQGKPLAEAKGE------------ISYAASFIEWFAEEGKRIYGDTIPGHQA-DKRLLVIKQPIGVTAAITPWNFPSAMRKAGPALAAGCTMVLKPASQTPFSALALAELAQRA----GIPAGVFNVVTGSAGD-IGGELTSNPLVRKLSFTGSTEIGRQLMEQCKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLNQAVNKLAVGDGLQADVGNFFQPTILADVPDNAKVAKEETFGPLAPLFRFSDEADVIRQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREG----SKYGIEDYLEIKYMCIG...... 481
3 -68.000IDP00949 gene: hpaE; 4-hydroxyphenylacetate catabolism STM1102 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  13  41.VNQAVAAAKEAFPKWANLPMKERARLMRRLGDLIDQHVPEIAAMETADTGLPIHQTKNV-----------LIPRASHNFEFFAEVCQQMNGKTYP--VDDKMLNYTLVQPVGVCALVSPWNVPFMTWKVAPCLALGNTAVLKMSELSPLTADRLGELALEA----GIPAGVLNVVQGYGAT-AGDALVRHHDVRAVSFTGGTATGRNIMKNAKKYSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPTDPNTGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREG----GEYSFEVFAEMKNVCISMGD... 480
4 -66.800IDP01530 gene: yneI; putative succinate-semialdehyde dehydrogenase [Salmonella typhimurium LT2] STM1524 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  13  31.IEHALSLAASGFKKWKMTSVAQRAQTLRDIGQALRAHAEEMAQCITREMGKPIKQARAE------------VTKSAALCDWYAEHGPAMLNPEPTLV--ENQQAVIEYRPLGVILAIMPWNFPLVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEA----GTPAGVYGWVNANN--EGVSQMINDPRIAAVTVTGSVRAGAAIGAQAKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAFTDRFVAAAAALKMGDPLVEENGNYYAATVLADVTPDMTAFRQELFGPVAAITVAKDAAHALALANDSEFGLSATIFTADDTLAAEMAARLECGGVFINGYSASDARVAFGGVKKSGFGREL----SHFGLHEFCNVQTVWKN...... 460
5 -66.300IDP00969 gene: ydcW; putative aldehyde dehydrogenase STM1597 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  14  41.VDAAVQAADNAFAEWGQTTPKARAECLLKLADSIEQNALEFARLESQNCGKPLHCVIN-----------DEIPAIVDVFRFFAGAARCLSGLAAGEYLE-GHTSMIRRDPIGVVASIAPWNYPLMMWKLAPALAAGNCVVIKPSEITPLTALKLAVLA-----KDIFPPGVLNVLFGRGQT-VGDVLTGHEKVRMVSLTGSIATGEHILRHTKRTHMELGGKAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAACRIYAQRGIYDALVEKLGNAVSSLKMGAPEDESTGYYFAPTLLADAKQEDAIVQREVFGPVVSITVFDDEDQVLRWANDSRYGLASSVWTQDVGRAHRLSARLQYGCTWINTHFMLVSEMPHGGQKQSGYGKDM----SLYGLEDYTLVRHIMVK...... 473
6 -65.100IDP00699 gene: betB; betaine aldehyde dehydrogenase SACOL2628 [Staphylococcus aureus subsp. aureus COL]  ali follow..  15  48.AERAILAARRAFESWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYAD------------MDDIHNVFMYFAGLADKDGGEMIDSPIP-DTESKIVKEPVGVVTQITPWNYPLLQWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEV----GFPKGTINLILGAGSE-VGDVMSGHKEVDLVSFTGGIETGKHIMKNATNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGREL----GKEGLEEYLVSKHILTNTNP... 488
7 -38.500IDP00001 aldehyde-alcohol dehydrogenase BA_4599 [Bacillus anthracis str. Ames]  ali follow..  15  18.IDTLVNNGRKALQALESFTQEQIDNIVHEMALAGVDQHMPLAKLAVEETG-----GVYEDKCIKNIFATEYIWHSIKKDKTVGIIHE-----------DPHEEIIEIAEPVGVVAGVTPVTNPTTMFKALIAIKTRNPIIFAFHPSAQNCSVAAAKTVYDAAVKAGAPKHCIQWIEKPSVEATKQLMN-HEGVALVLATGGAGMVKSAYSTGK-PALGVGPGNVPCYIEKSAHIKAVNDLILSKTFDNGMICASEQAIIVDKEIYDDVKTEMITNAELVGITVPKNTKM------VAEIQGIGAAYPLSREKLSPVLACVKANSLEEGFTYCEEGGLGHSAVIHSVNKEVQKQFGLRMKACRLIVNAPSSQGGIGDIYNGFIPSLTLG............................ 427
8 -36.900IDP00757 alcohol dehydrogenase, iron-containing SACOL0135 [Staphylococcus aureus subsp. aureus COL]  ali follow..  15  21.IDALADKGKKALEALSKKSQEEIDHIVHQMSLAAVDQHMVLAKLAHEETG----RGIYEDKAIKNLYASEYIWNSIKDNKTVGIIGE-----------DKEKGLTYVAEPIGVICGVTPTTNPTTIFKAMIAIKTGNPIIFAFHPSAQESSKRAAEVVLEAAMKAGAPKDIIQWIEVPSIEATKQLMN-HKGIALVLATGGSGMVKSAYSTGK-PALGVGPGNVPSYIEKTAHIKAVNDIIGSKTFDNGMICASEQVVVIDKEIYKDVTNEFKAHAELAGIPVPENTKL------IAEISGVGSDYPLSREKLSPVLALVKAQSTKQAFQICEDGGLGHTAVIHTEDETLQKDFGLRMKACRVLVNTPSAVG----GIGDMYNELIPSLTLGCGSYG................... 435
9 -35.100IDP02645 gene: adhE; bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Salmonella typhimurium LT2] STM1749 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  9.LNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESG----MGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSE-----------DDTFGTITIAEPIGIICGIVPTTNPTAIFKSLISLKTRNAIIFSPHPRAKEATNKAADIVLQAAIAAGAPKDLIGWIDQPSVELSNALMH-HPDINLILATGGPGMVKAAYSSGK-PAIGVGAGNTPVVIDETADIKAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFASHAELAGFSVPETTKI------IGEVTVVDESEPFAHEKLSPTLAMYRAKDFEEAVEKAEKGGIGHTSCLYTDQPERVAYFGQMMKTARILINTPASQGG---IGDLYNFKLAPSLTLGCGSWG................... 425
10 -8.760IDP01913 gene: hisD; histidinol dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1426 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  10  18LRENANIIEETVQRSVREIVQNVRDEALSFYTKKFDGVEIKDVRVSEEEIKQASMF-----------VESSFLEALQEAKKNIISYHEKQKRQSMFDCTSKGIIRGQIIRPLENIGVYVPGGPSSVLMNVLPAKLAGKIVMVTPPRAGGIDPHILV-----AASLAGVD----EIYMIGGAQAIAALTESIPKVDKIVGPGNLALAKREVYGIVNIDMIAGPSEIVVIADETGNAKYIAADLLSQAEHDERATAIC--ITTNIELAKEVEKEIERQLETL------------------------PRSEIARESINRNGAIFIVPSIDEALQLSNEIAPEHLELHIKEPMNALAYVK---HAGSIFLGPYAPEPLGDYLAGPNHVLPTSGTARFFSPLSVDDFVKKSSFL........ 391

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;