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Query: IDP92048 thioredoxin, putative [Toxoplasma gondii ME49] TGME49_049270 [Toxoplasma gondii ME49], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MALAQTQHLALLLAVLSVLTGAQAGLYAPNGPVKVLSGQQFKEQVVGSNDLFIVEFYADWCGHCQRFAPEFEKAAKALRGIVTLVAVSDQSAMGEYGVQGFPTVKAFVGRGGKPPKTFDYNQGRDAASLIEFAVMHAGKLARARLAGKIDAGTDAKPSEKAGSPEKETSDVIELTDGNFNQLVMKDDKSVWFVEFYAPWCGHCKALAPTWEEVATALKGKVKVGKVDATVEKVLASTYGIRGFPTLKLFPAGEKSVGLVKDYEGARTTEALLKYAMEFFSVNVTTEQLLNESQFRKACGDQLCVLAFLPHILDSKTEKRNEYLATLNRVVRASFHMPIAFFWSQGGDQYEFEEQLNLAFGYPAVVAVHLSKGKYAIHRGDFSQESINTFLTQLLAGKAPISELPKNLKKLEESRAWDGKDEELPKDELLast
1 -112.000IDP92048 thioredoxin, putative [Toxoplasma gondii ME49] TGME49_049270 [Toxoplasma gondii ME49]  ali  100  1MALAQTQHLALLLAVLSVLTGAQAGLYAPNGPVKVLSGQQFKEQVVGSNDLFIVEFYADWCGHCQRFAPEFEKAAKALRGIVTLVAVSDQSAMGEYGVQGFPTVKAFVGRGGKPPKTFDYNQGRDAASLIEFAVMHAGKLARARLAGKIDAGTDAKPSEKAGSPEKETSDVIELTDGNFNQLVMKDDKSVWFVEFYAPWCGHCKALAPTWEEVATALKGKVKVGKVDATVEKVLASTYGIRGFPTLKLFPAGEKSVGLVKDYEGARTTEALLKYAMEFFSVNVTTEQLLNESQFRKACGDQLCVLAFLPHILDSKTEKRNEYLATLNRVVRASFHMPIAFFWSQGGDQYEFEEQLNLAFGYPAVVAVHLSKGKYAIHRGDFSQESINTFLTQLLAGKAPISELPKNLKKLEESRAWDGKDEELPKDEL 428
2 -69.200IDP92071 protein disulfide isomerase [Toxoplasma gondii ME49] TGME49_011680 [Toxoplasma gondii ME49]  ali follow..  16  1MRA----GFSFALLAVGLLATAVVYSAAEEEAVTVLTASNFDDTL-KNNEIVLVKFYAPWCGHCKRMAPEYEKAAKTLKELAKVDATSETDIADKQGVREYPTLTLFRKEK-----PEKYTGGRTAEAIVEWIEKMTGPAVTEVEGSAEDKVTKEAPIAFVAELASKDSDMAKLTKDELKKFVDTESDRDLDLVWLCGTEKDFDEAKTAVREAAKKLRDTRSFVWLDTDQFKGHAENALGITEFPGLVFQSKKGRFVLPEATTSLKDAAKISQFFDDVEAGKIDRSLKSKNFEEMVIQKDKDVMLEIYAPWCGYCKSFEPIYKEFAEKYKD---VDHLVVAKMDGTANETPLEEFSWS-SFPSIFFVKAGEKTPMKFEGSRTVEGLTEFVNKHGSKPLKKDDKGEEL..................... 471
3 -42.100IDP91755 TXD11_HUMAN [Homo sapiens]  ali follow..  12  64ELLCGAVALGCALLLALKFTCSRAKFFSLRSPVLDLFQGQLDYAVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDFVAINCWWNQGKCRKKHFFYFPVIYLYHRSFG----PIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSTAENICKWALENQETLFRWLRPHGGKSLLLNNKKGPALFLFSVPHIEENRYLFPEVDMTSTNFTGTLNIYLLDSNLFWLYAERLGAPSSTQFAAIVDVKEESHYILDPKQALMKLTLESFIQNFSPSQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMD----TFTVARIDVSQN-DLPWEFMV-DRLPTVLFFPCNRKDKYPEDVPITLPNLLRFILHHSDPASSPQNVANS...................... 783
4 -36.700IDP02293 gene: trxA1; thioredoxin [Francisella tularensis subsp. tularensis SCHU S4] FTT1445 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  22  2..............................SKCIDISDSQFESEVVNSDIPVLLDFWAPWCGPCKMLAPILDQVTEHYGDVCKINIDDNEETAMKFGVRGVPTLMVFKDGENKETKV----GVVQKTQLISIVDKYL................................................................................................................................................................................................................................................................................................... 107
5 -34.800IDP02326 gene: trxA2; thioredoxin [Francisella tularensis subsp. tularensis SCHU S4] FTT0976 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  22  2............................ALSNVIKTDEANFDKLIDNTNKAVLVDFYADWCGPCKTLAPILDQLSKDYTKIVKVNVDENQNLAARFAIRSIPTLIVFKNRKQ----LETLMGVHTASQLEQKLKA..................................................................................................................................................................................................................................................................................................... 106
6 -33.800IDP04067 thioredoxin [Bacillus anthracis str. Sterne] BAS4417 [Bacillus anthracis str. Sterne]  ali follow..  31  2.........................................................................................................................................................................AIVNANDQSFAAETSEG---VVLLDFWAPWCGPCKMIAPVLEEIDAELGEKVKVVKVDVDENQETARQFEVMSIPALFVLKDGKVVDQAL----GYKPKEALVELVSKHF..................................................................................................................................................... 104
7 -32.800IDP04482 gene: trxC; thioredoxin 2 [Yersinia pestis CO92] YPO3270 [Yersinia pestis CO92]  ali follow..  29  34.......................................................................................................................................................................DGEVINATAETLDKLL--QDDLPMVIDFWAPWCGPCRSFAPIFAETAAERAGKVRFVKVNTEAEPALSTRFRIRSIPTIMLYRNGKM----IDMLNGAVPKAPFDNWLDEQLSRDPNS............................................................................................................................................... 145
8 -31.800IDP02772 gene: trxC; thioredoxin 2 [Salmonella typhimurium LT2] STM2649 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  33  34.......................................................................................................................................................................DGEVINATGETLDKLL--KDDLPVVIDFWAPWCGPCRNFAPIFEDVAEERSGKVRFVKVNTEAERELSARFGIRSIPTIMIFKHGQVVDMLN----GAVPKAPFDSWLNEAL..................................................................................................................................................... 139
9 -25.600IDP01793 gene: ybbN; putative thioredoxin protein [Salmonella typhimurium LT2] STM0504 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  20  2......................................................................................................................................................................SVQNIVNINESNLQQTLEQSMTTPVLFYFWSERSQHCLQLTPVLESLAAQYHGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQP----VDGFQGPQPEEAIRALLDKVLPREEELKAQQAMQ........................................................................................................................................ 123
10 -14.600IDP01748 gene: srgA; putative thiol-disulfide isomerase or thioredoxin [Salmonella typhimurium LT2] PSLT011 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  10  1MTMNYARDLFSLKGILFSFLLAGCVCPVVAQEWESITPP-------VVDAPAVVEFFSFYCPPCYAFSQTMQAIRHVLPQGSRMELTRAWALAMVMKETDVIEKAFFTAGMVEKRLHS------PDDVRRVFMSAT-------------------------------------ISRGEYDRSIKSPAVNDMV------------------------------------ALQERLFKEYGVRGTPSVYVRGRYHINNAAFGAFSVENFRSRYAAVVRKLLAGN.................................................................................................................................................. 213
11 -12.900IDP01816 putative disulfide bond formation protein [Salmonella typhimurium LT2] STM3193 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  1MSSKWISLFKSVVLTAALVTPFAASAFTEGTDYMVLEKPI------PNADKTLIKVFSYACPFCYKYDKAVTGPVS-------------DKVADLVTFTPFHL---------------ETKGEYGKQASEVFAVLIAKDKAAGISLFDAKSQFKKAKFA-----------WYAAYHDKKERWSDGKDPAAFIKTGLDAAGMSQADFEAALKDPAVQET---------LEKWKAAYDVAKIQGVPAYVV------NGKYLIYTKNIKSIDSMAELVRELATKK.................................................................................................................................................. 223
12 -12.900IDP91959 thioredoxin family protein [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100000757 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  15  1MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQDFELMGVDGKKKVYLKFWASWCSICLASLPDTDEIAKEAGD-LPVLVDPSGKLLETYGVRSYPTQAFI---DKEGKLVKTHPGFMEKDAILQTLKELA................................................................................................................................................................................................................................................................................................... 188
13 -12.800IDP95296 thiol:disulfide oxidoreductase related to ResA [Clostridium botulinum H04402 065] YP_005676832 [Clostridium botulinum H04402 065]  ali follow..  15  1MKNNKRYIYISVIMLVLLVDKNSSFQPAVDFTVYDKDNNEVKLSDYKGKKAVVVNFWASWCSPCKYEMPHFQEATNKYNNILMVNLTDNLDAANKYQLNAIPRTVFI---DKEGNLVYDHVGIIDKEILDENIDKIIN.................................................................................................................................................................................................................................................................................................. 188
14 -12.100IDP02290 ahpC/TSA family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA3674 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  18...............................................................................................................................AAYEQFGKSDQAAQGEQEKSEAAMKEMIASNGIEIGKSAPDFELTKLDGTNIK--LSDLKGKKVILNFWATWCGPCQQEMPDMEAFYKKHKDNVEILAINYTPSEDVTTAYKVITIPTSYFI---DTKGVIQDKFIGPMTQKEMEKRIAK....................................................................................................................................................... 189
15 -12.000IDP91802 gene: dsbA; thiol:disulfide interchange protein DsbA [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] lpg0123 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]  ali follow..  11  1MLIIFKGYIELIALLFLMPMTALATQFIEGKDYQTVASA--QLSTNKDKTPLITEFFSYGCPWCYKIDAPLNDWATRMGKGAHL-YAKAYYTAKTLAMSDKMNPILFKAIQEDKNPLA------TKQSMVDFFVAH-------------------------------------VDREIAKSAFEN----------------------------SPTIDMRV-------NSGMSLMAHYQINAVPAFVV---NNKYKTDLQMAGSEERLFEILNYLVRKSA.................................................................................................................................................... 217
16 -11.900IDP95297 hypothetical protein SPy_1558 [Streptococcus pyogenes M1 GAS] NP_269625 [Streptococcus pyogenes M1 GAS]  ali follow..  16  71....................APDFELKGIDGKTYRLSE---------KGKKVYLKFWASWCSICLSTLADTEDLAKMSDK-LPVLLDPDGKLLEAYGVRSYPTEVFI---GSDGVLAKKHIGYAKKSDIKKTLKG..................................................................................................................................................................................................................................................................................................... 205
17 -11.700IDP02519 gene: resA; thiol-disulfide oxidoreductase [Bacillus anthracis str. `Ames Ancestor`] GBAA1494 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  14  1MKKNRLLFRVIILLILSGAVGFTLYQGFFADKEFVVTDLEGKKIELKDGKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKFPVAIDKGQKIIGTYGVGPLPTSFLI---DKDGKVVEQIIGEQTKEQLEGYLKK..................................................................................................................................................................................................................................................................................................... 170
18 -11.700IDP02734 thioredoxin family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA1779 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  13................................................................................................................................LIWAGVNFYNSKKEEKERKAKQAELQKTEVLPQVGFKAPDITLKGLDGKLYS--LHDAKGKPYLINFWASWCGPCEMEAPDLVCMYDKYKKDVEIFAVNATMDGVAGLDYKVFSLPTTFFV---NKDGIIVEQVRGVLPPDQLEEKFKKLIES................................................................................................................................................... 184
19 -11.600IDP93841 putative thiol:disulfide oxidoreductase, nitrite reductase complex assembly [Yersinia enterocolitica subsp. palearctica Y11] YP_006003984 [Yersinia enterocolitica subsp. palearctica Y11]  ali follow..  12  1........MLAFVLGLVLYSGLNRDPHHVELAEKNLPFPEFSLSELQQPKVTVINVWASWCASCKQELAVLGQIASSLNQVQFYGVNPQGVLALAMGVYGTPETWLI---DADGIIRQRYAGEMTQEIWQQQFAPLLTQWAKV............................................................................................................................................................................................................................................................................................. 168
20 -11.000IDP95299 thioredoxin family protein [Enterococcus faecalis Merz96] EEU68760 [Enterococcus faecalis Merz96]  ali follow..  22  48...............................STKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKS-VVTDPVDDNGNGRLNGIQAMPETFFVDSNGE............................................................................................................................................................................................................................................................................................................................ 164
21 -11.000IDP95300 gene: tlpA; thiol:disulfide interchange protein TlpA [Clostridium tetani E88] NP_780861 [Clostridium tetani E88]  ali follow..  17  1MINLKKKVTIFLILILIILSSVFYKFYVDKNQKDIDNKSDFKLKDLNDKKKVMLNFWATWCGYCVQEMPYMQNIHNETKDILAVNVGERQEVAQNYGVQAFPTTLFI---DEEGFVYSGIQGPMTDDIMRKELK...................................................................................................................................................................................................................................................................................................... 185
22 -10.800IDP95295 thioredoxin [Streptococcus mutans UA159] NP_721554 [Streptococcus mutans UA159]  ali follow..  17  1MKKVILPLALGVTLLGIGLTNQTTSFAQGKTSPKKLKNKKGKTVSLSAGKKVYINVWATWCGPCMREIPDLEKIYQTYKHFLSVTSPNQDNFTQAYGIRSIPTHIFI---NSDGSLSEKIAGGLDEDSLKYYLKK..................................................................................................................................................................................................................................................................................................... 185
23 -10.700IDP95298 thioredoxin family protein [Peptoclostridium difficile] WP_021368768 [Peptoclostridium difficile]  ali follow..  20  84....................SIDFTLTDQYGKTHKLSD---------EGKVVFLNFWATWCPPCKEEMPYIEQLYKDYNKILGVASPEDGALAYQYGINAFPTTFII---DKEGYVTQYIPGAMDKATMASFIENQRNK................................................................................................................................................................................................................................................................................................. 224
24 -10.300IDP01316 glutaredoxin, putative VC1616 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  16  4....................................................VVLYIKDKCPHCKDAQRYLDSKGIKYRLC-NAKMERGRKELDALGARSVPVLKI.................................................................................................................................................................................................................................................................................................................................. 56
25 -9.260IDP91412 transcriptional regulator [Vibrio vulnificus CMCP6] VV1_0715 [Vibrio vulnificus CMCP6]  ali follow..  34..................................................................................................................................................................................................................................................................................VASYGEIVLQGKGTAFQPWASSQMLGKVRVIQAIAGRSSSKEMNAPLMQAITAAQFSADHYQTTTIINQDDDENGVVASSWQLDKESSAIIVQDKQGKVLFVKEGALSSDDITQVLELIKA................................. 181

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.