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Query: sp|Q9H013|ADA19_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 19 OS=Homo sapiens GN=ADAM19 PE=1 SV=3 (Range: 451-750), from H.sapiens

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKLast
1 -62.400[O] KOG3607 Meltrins, fertilins and related Zn-dependent metalloproteinases of the ADAMs family  ali follow..  29  562DAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKD-GDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQG---RVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNLDEGPKGPSATNLIIGSIAGAILVAAIVLGGTGWGFKNVKKRRFDPTQQGP................................... 831
2 -39.300[W] KOG3658 Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases  ali follow..  12  589RQESECSNLQTCDGRNAQCPVSPPKHDGIPCQDSTKVCSSGQCNGSVEDCFLTEGKADELCFLACIKDGKCTSSVHLPEFSANRTNFLQNMRKDKPGLILHP---------------------------------------------------GSPCNNGYCDIFRKCRSVDANGLARLKNLLFNKRTIETLTQWAQDNWWVVGVGGLVFLVIMALFVKCCAVHTPSTNPNKPPALNIYQTLTRPGTLIRQHRQRHRAAAGSVPPGPGAQPRSGAASAPSRTTPSARPSAPPLVAPQVAV 846
3 -11.000[S] KOG4791 Uncharacterized conserved protein  ali follow..  20  3NQGEDC-FYSTCTGDS--CPCEAALGNETVCT--EGRCFRRVCRFRHMEIDK------KRSEIPCYWENQPTGCQKLNC............................................................................................................................................................................................................................. 80
4 -8.420[T] KOG3512 Netrin, axonal chemotropic factor  ali follow..  17  403...GRCK----CNGHASECVATVSSGSGTALSDQDD-SAPSLANHFGRSTQM-----SAKLTMTCACKHNTAGPECERCFYFDRPWGRATDNDANECKMCQCNGHARRCRFNLELYKLSGRVSGGVCYNCQH-------------------TTGRYC--------HYCREPPNHRKVCKRCDCHPVGTCNHSGQCPCKEGVTGLTCNRCARG........................................................................................ 597
5 -7.780[T] KOG4296 Epithelin/granulin  ali follow..  12  99DAETECSDDETCDNTWGCCP----MPNAVCCDDRSHCCPTGTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNETCCLLEQGSYGCCPVPNAVCNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDSTSSEDPESDVDPIACGVGKTC-KTTCCNVRGKNGEPKTMCCSNFNFRPSAVRT-LAAQPA---ITVLM.......................................................................................... 335
6 -7.610[R] KOG3002 Zn finger protein  ali follow..  17  56....ECPV---C---TNLMYPPIHQ-----CPNGHTLC--SSCKLRVQNCRYELGNIRCLALEKVAESLEVRYQNLG-CQDSKLKHEQHCRFRSYSC-GSECSVTGDIPTLVDHLK........................................................................................................................................................................................ 166
7 -7.250[S] COG4306 Uncharacterized protein conserved in bacteria  ali follow..  18  1..MGTYRAAQICTNGHVATTA------DQKHELWEAFC---------SHS----GEATILQYPKCSASIRGDDYVEGVLGFGGDYEPPTCNN----CGS......................................................................................................................................................................................................... 76
8 -7.060[R] KOG4323 Polycomb-like PHD Zn-finger protein  ali follow..  20  187......................................................................................................................................................VDMVTLC---SVCQRGHSPLSNRI--------CDG---CNSPYHQLCDAEWFCMKCQYR........................................................................................... 246
9 -7.040[K] KOG1244 Predicted transcription factor Requiem/NEURO-D4  ali follow..  14  270..............................................NNYCD------------FC------LGDSKINKKTGQPEELVSCSD----CGR-SCLQFTPVMMAAVKTY-------------------------------------RWQCIECKCC--NICGTSE---NDDQLLFCDD---CDRGYHMYCEGSWSCHLCLDLLKEKASIYQNQNSS............................................................................. 391
10 -6.710[O] COG5243 HRD ubiquitin ligase complex, ER membrane component  ali follow..  301..................................................................................................................KDVVWDILALYQSGTSLWKIWRNNKQLDDTLVTVTVEQLQNSANDDNICI---CMDELIHSPNQQTWKNKNKKPCGHILHLSCLKNW--PICRLPVFDEKGNVVQTTFTSNSDITTQ-------------------TTVTDSTGIATDQQGFANEVDLLPTRTTSPDIRIVPTQNIDTLAMRTRST 474

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Topczewski J, Godzik A., Paszewski A. The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases. Microbiology. 2000 Oct;146 ( Pt 10):2695-703.