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Query: sp|Q9H013|ADA19_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 19 OS=Homo sapiens GN=ADAM19 PE=1 SV=3 (Range: 451-750), from H.sapiens

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQEQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQCQSSEARPLESNAVPIDTTIIMNGRQIQCRGTHVYRGPEEEGDMLDPGLVMTGTKCGYNHICFEGQCRNTSFFETEGCGKKCNGHGVCNNNQNCHCLPGWAPPFCNTPGHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSALPSKLRQQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKLast
1 -74.4003g5c_A mol:protein length:510 ADAM 22  ali model follow..  31  273EAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQGICFGGRCKTRDRQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCGKD-KDTWIQCNKRDVLCGYLLCTNIGNIPRLGELDGEITSTLVVQQ--GRTLNCSGGHVKLE-EDVDLGYVEDGTPCGPQMMCLEHRCLPVASFNFSTCGTICSGNGVCSNELKCVCNRHWIGSDCNTYFHNDDAKTGITLSGNGVA......................................................................... 501
2 -51.6002dw0_A mol:protein length:419 Catrocollastatin  ali model follow..  32  271ASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCF-ERNQKGNYYGYCRKE-NGNKIPCAPEDVKCGRLYCKDNSPGQ------------------------NNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNGHCVDVATA.............................................................................................................................. 418
3 -51.4003k7n_A mol:protein length:397 K-like  ali model follow..  37  255VAKDDCDLPELCTGQSAECPTDSLQRNGHPCQNNQSYCYNGTCPTLTNQCITLLGPHFTVSPKGCF-NLNMRGDDGSFCRME-DGTKIPCAAKDVKCGRLYCTEKNTMSCL------------------------------IPPNPDGIMAEPGTKCGDGMVCSKGQCVDVQTA.............................................................................................................................. 396
4 -51.2003hdb_A mol:protein length:417 AAHIV  ali model follow..  33  269ASMSECDPAEHCTGQSSECPADVFHKNGEPCLDNYGYCYNGNCPIMYHQCYALFGADIYEAEDSCF-ESNKKGNYYGYCRKE-NGKKIPCASEDVKCGRLYCKDDSPGQ------------------------NNPCKMFYSNDDEHKGMVLPGTKCADGKVCSNGHCVDVTTA.............................................................................................................................. 416
5 -50.8003k7l_A mol:protein length:422 Atragin  ali model follow..  35  277AAKDDCDLPELCTGQSAECPTDVFQRNGLPCQNNQGYCYNGKCPIMTNQCIALRGPGVKVSRDSCF-TLNQRTRGCGLCRME-YGRKIPCAAKDVKCGRLFCKRRN---------------------------SMICNCSISPRDPNYGMVEPGTKCGDGMVCSNRQCVDVKTA.............................................................................................................................. 421
6 -50.6002e3x_A mol:protein length:427 Coagulation factor X-activating enzyme heavy chain  ali model follow..  33  273RARDECDVPEHCTGQSAECPRDQLQQNGKPCQNNRGYCYNGDCPIMRNQCISLFGSRANVAKDSCF-QENLKGSYYGYCRKE-NGRKIPCAPQDVKCGRLFCLNNSPRN------------------------KNPCNMHYSCMDQHKGMVDPGTKCEDGKVCNNKRCVDVNTAYQSTT......................................................................................................................... 426
7 -50.6003dsl_A mol:protein length:419 Zinc metalloproteinase-disintegrin bothropasin  ali model follow..  33  271ASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYALFGADVYEAEDSCF-KDNQKGNYYGYCRKE-NGKKIPCAPEDVKCGRLYCKDNSPGQ------------------------NNPCKMFYSNDDEHKGMVLPGTKCADGKVCSNGHCVDVATA.............................................................................................................................. 418
8 -48.0002ero_A mol:protein length:427 vascular apoptosis-inducing protein 1  ali model follow..  32  280AAKDECDMADVCTGRSAECTDRFQRNGQ-PCKNNNGYCYNGKCPIMADQCIALFGPGATVSQDACF-QFNREGNHYGYCRKE-QNTKIACEPQDVKCGRLYCFPNSPEN------------------------KNPCNIYYSPNDEDKGMVLPGTKCADRKACSNGQCVDVTTP.............................................................................................................................. 426
9 -23.9006be6_A mol:protein length:449 Disintegrin and metalloproteinase domain-containing protein 10  ali model follow..  16  312RDDSDCAREGICNGFTALCPASDPKPQFTDCNRHTQVCINGQCAGSECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQ-WSRHFSGRTITLQPGS-PCNDFR.................................................................................................................................................................................................. 423
10 -22.2005l0q_A mol:protein length:203 Disintegrin and metalloproteinase domain-containing protein 10  ali model follow..  15  76RDDSDCAKEGICNGITALCPASDPKPNFTDCNRHTQVCINGQCEKHGLEECTCASSDGKDDKELCH-VCCMKKMEPSTCASTGSNKYFLGRTITLQPGS-PCNDFR.................................................................................................................................................................................................. 187
11 -18.5004k0v_A mol:protein length:529 TEK tyrosine kinase variant  ali model follow..  22  172.IGGNLFTSAFTRLIVRRCEAQKW---GPECNHLCTACMNGVCHEDTGECICPPGFMGRTCEKAC------ELHTFGTCKERCSGQ-VFCLPDPYGCS---CATG-----------------------------------------------KGLQCNEGPDC-KLRC-------------SCNNGEMCDRFQGCLCSPGWQGLQCEREGIPRMTPKI.................................................................................. 330
12 -16.0003ghn_A mol:protein length:419 A disintegrin and metalloproteinase with thrombospondin motifs 13  ali model follow..  20  43EHLDMCQ---SCHLDQSSCSRLLVLLDGTECGVEK-WCSKGRCRSLVEPCSRSCGGGVVTRRRQCNNPRPAFGGRA--C-VGADLQAEMCNTMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGD--SFLDGTRCGTLSLCVLGSCRTFGRMDSQQVWDRC---QVCGDNSTCSPRKG.................................................................................................... 276
13 -13.4002ygo_A mol:protein length:188 WNT INHIBITORY FACTOR 1  ali model follow..  21  130.............................................................................................................................................................GNTILKTPQNAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEGT........................................................................................... 181
14 -13.0002ygq_A mol:protein length:324 WNT INHIBITORY FACTOR 1  ali model follow..  22  152..PGGCRNGGFCNERRIECPDGF---HGPHCEKATPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNG---GTC---FYPGKCICPPEGEQCEISKCPQP---------------------------------------------CRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR........................................................................................... 309
15 -12.9005uk5_B mol:protein length:318 Protein jagged-1  ali model follow..  21  159....TCDDHYYGFGCNKFCRPRDDFFGHYACDQGNKTCMEGECNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN-EPWQC---LCETN-----------------------------------------------GGQLCDKDL----NYC---------GTHQPCLNRGTCSNTGQCSCPEGYSGPNCEA............................................................................................ 308
16 -12.6005e6w_A mol:protein length:317 Integrin beta-2  ali model follow..  20  185.................ECRCRDQSRDRSLC-HGKGFLECGIC-----RCDTGY------IGKNCECQTQGRSSQELEGSCRKDNNSIICSGLDCVCGQCLCHTSD----------------------------------------------VPGKLIYGQYC---ECDTINCERYNGQVCGGPGRGLCFC-GKCRCHPGFEGSACQ............................................................................................. 313
17 -12.5002jih_A mol:protein length:300 ADAMTS-1  ali model follow..  19  192...SPCSITSFLDNGHGECLMDKPQNPIQLPGDLPGTSY-----DANRQCQFTFGEDSKH-----------------------------CPDAASTCSTLWCTGTSGGVLVCQTKHFPWA--------------------------------DGTSCGEGKWCINGKCVNKLV............................................................................................................................... 298
18 -12.3002rjp_A mol:protein length:316 ADAMTS-4  ali model follow..  19  193...SPCSITDFLDNGYGHCLLDKPEAPLHLPV-----TFPGKDYDADRQCQLTFGPDSRH-----------------------------CPQLPPPCAALWCSGHLNGHAMCQTKHSPWA--------------------------------DGTPCGPAQACMGGRCLHMD................................................................................................................................ 298
19 -12.1004cbz_A mol:protein length:312 PROTEIN JAGGED-1  ali model follow..  21  155....TCDDYYYGFGCNKFCRPRDDFFGHYACDNGNKTCMEGECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICN-EPWQC---LCETN-----------------------------------------------GGQLCDKDL----NYC---------GTHQPCLNGGTCSNTGQCSCPEGYSGPNCEI............................................................................................ 304
20 -12.1005mw7_A mol:protein length:332 Protein jagged-2  ali model follow..  18  171....RCDENYYSATCNKFCRPRNDFFGHYTCQYGNKACMDGECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCV-EPWQC---NCETN-----------------------------------------------GGLLCDKDL----NYCG---------SHHPCTNGGTCINAERCTCPDGYSGRNCEKA........................................................................................... 321
21 -11.7004xl1_B mol:protein length:230 Delta-like protein  ali model follow..  28  138NTLTRLRYSYRV-----VCSDNYY---GDSCSR---LCKKRDDHFGHYECQP---------------------------------------------GSPSCLPG-----------------------------------------------TGKYC-DQPICLSGCHEQ---------------NGYCSKPDECNCRPGWQGPLCNE............................................................................................ 228
22 -11.6005mw5_A mol:protein length:293 Protein jagged-2  ali model follow..  20  171.................RCDENYY---SATCNK---FCRPRNDFFGHYTC-------DQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVP----GECRCSYG-----------------------------------------------QGRFCD------------------ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKD........................................................................................... 281
23 -11.6002ech_A mol:protein length:50 ECHISTATIN  ali model follow..  34  21KRARGDDMDDYCNGKTCDCPRNPHKGPATX.............................................................................................................................................................................................................................................................................. 50
24 -10.9003m0c_C mol:protein length:791 Low-density lipoprotein receptor  ali model follow..  12  5.....LRWTVALLLAAAGVGDR--------CERNEFQCQDGKCISYKWVC---------DGSAECQDGSDESQELSVTCKSGD----FSCGGRVNRCQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFV--DSDRDCLDGSDEASCPVLTCCNSSTCIPQL--------WACDNDPDCSDEWPQRCRGLYVFQGDSSPCSAFE...................................................................................... 198
25 -10.8005mvx_A mol:protein length:309 Delta-like protein 4  ali model follow..  18  148....ICSDNYYGDNCSRLCKKRNDHFGHYVCQPGNLSCLPGYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCS-TPWQC---TCDEG-----------------------------------------------GGLFCDQDL----NYCTH---------HSPCKNGATCSNSGTCTCRPGYTGVDCELE........................................................................................... 298
26 -10.7004xlw_B mol:protein length:261 Delta-like protein  ali model follow..  24  141.........RLRYSYRVVCSDNYY---GDSCSRGHYEC-DGSP-----SCLPGW-TGKYCDQPICLSGCHEQN---GYC------------SKPDEC---NCRPG-----------------------------------------------QGPLCN------------------ECIPHKGCRHGTCTIPWQCACDEGWGGLFCDQA........................................................................................... 259
27 -10.6002m74_A mol:protein length:136 Fibrillin-1  ali model follow..  24  79..........................................................................................................................................................IRCMNGGSCSDDHCLCQKGYIGTHCGQPCLNGGRCVAPNRCACTYGFTGPQCE............................................................................................. 136
28 -10.5004u8u_N mol:protein length:236 Linker L2  ali model follow..  13  43....HEAEKIDPEGFIKELDARVSHVEGTHCAKKEFQC-DQECISDLFVC-----------------------DGHKDCHNGHDEAEDVCDTSPVKPGNIFTSHWHDCLLRSDHVTRVVIKGTIRRNYFKSRIWVRAQIESDLIHDGKKELSDFDSKGYYNFANRRLVLIPIAQDDKHLSVICDFDRGDSRRASCHRVLEGTLHQCAN............................................................................................ 227
29 -10.3001wgc_A mol:protein length:171 WHEAT GERM LECTIN  ali model follow..  16  18.....CSQYGYCGMGGDYCGKGCQNGACWTCTNNQCCSQYGYCGFGAEYCGAGCQGGPCRADIKCGSQAGGKLCPNNLC-----SQWGFCGLGSEFCGG------------------------------------------GCQSGACSTDKPCGKDAGGRVCTNNYC--------------CSKWGSCGI-GPGYCGAGCQSGGCD............................................................................................. 170
30 -10.3001k7t_A mol:protein length:186 agglutinin isolectin 3  ali model follow..  13  1.........ERCGEQG----------SGMECPNNLCCSQYGYCGMGGDYCGKGCQNGACWTSKRCGSQAGGKTCPNNHC-----SQYGHCGFGAEYCGA-------------GCQGGPCRADIKCGSQAGGKLCPNNLCCSQWGYCGLGSEFCGEGCQNGACSTDKPCGKDAGGRVCTNNYCCSKWGSCGI-GPGYCGAGCQSGGCDGVFAEAIATNS.................................................................................. 181
31 -10.3004xbm_A mol:protein length:531 Delta-like protein 1  ali model follow..  13  267QDLNYCTHHKPCKNGATSCRPGY---TGATCELGIDECDPSPCKNGGSSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSNCEKKIDYCSSSPCSNGAK------------------VDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGSCTCPPGYTGRNCSAPCHNGATCHQRGHCECARSYGGPNCQFL........................................................................................... 499
32 -9.9405e6v_A mol:protein length:224 Integrin beta-2  ali model follow..  11  1.........EECKFKVSSCRE---------CIESGPGC--TWCQKLNIRCDTRPQLLMRGCAADDIMDPTSLAETQEDHNGGQKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYSRVFLDHALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQEQSFDQSRDRSLCHGKGFLE--GICRCDTGYIGKNCE............................................................................................. 221
33 -9.9305ms9_A mol:protein length:177 Fibrillin-1  ali model follow..  13  2...........ASRSIQHCNIRC--MNGGSCSDDHCLCQKG----IGTHCGQPVCESGCLNGGRCVAP--------NRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVSTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL-------------CQG-GNCINTVECKCPAGHKLNEVSQK........................................................................................... 175
34 -9.6803b4v_C mol:protein length:237 follistatin-like 3  ali model follow..  11  2.GSGNPAPGGVCQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKI---MLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRG-RCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQEL-----------CGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPG...................................................................................................... 226
35 -9.5501z1x_A mol:protein length:64 disintegrin  ali model follow..  34  39KRAMLDGLHDYCTGVTSDCPRNRYNH.................................................................................................................................................................................................................................................................................. 64
36 -9.1902gtl_N mol:protein length:220 Extracellular hemoglobin linker L2 subunit  ali model follow..  13  26LDEAEKIDPEHFVSEID---ARVTKIEGTHCEKRTFQC-EQECISDLLVC-----------------------DGHKDCHNAHDEDPDVCDTSVVKAGNVFSGTSTWHGCLAREDHVTRITITASKRRKFFTARIWLRALVESELERHGENVTSSFNAKGYYNFASRRLILLPTDDHDDHLACSFNRGDNERAECHRVTEATLHQCAD............................................................................................ 211
37 -9.1703jd8_A mol:protein length:1278 Niemann-Pick C1 protein  ali model follow..  13  20VFSQSCVWYGECGDKRYNCEYSGPPKP-ELCFGNVSLC----CDV--RQLQTL-------------DNLQLPLQFLSRC---------SCFYNNLFC-ELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAMYN--------ACRDGLLC-ADACNATNWIEYNNATKGCD-ESVDEVTAPCSCQ------DCS-----IVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFSVNASDKGEASCCDPVSA... 329
38 -9.1203c05_B mol:protein length:64 Disintegrin acostatin-beta  ali model follow..  40  40RRARGDDLDDYCNGISAGCPRNPFH................................................................................................................................................................................................................................................................................... 64
39 -9.0205wdu_G mol:protein length:471 Envelope glycoprotein gp160  ali model follow..  14  5......................VTVYYGVPVAETTLFCASDA-KAYETEKHNVWAPTDPNPQEIHLENVTEEFNMWKNNMVEQDQSLKPCVKLTPLCVTLQCTNVTNNITDDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINENQGNRSNCNTSAICPKHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQF.............................................................. 257

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.