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Query: sp|Q99490|AGAP2_HUMAN Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens GN=AGAP2 PE=1 SV=2 (Range: 301-600), from H.sapiens

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst PATAVTAASAQPPGPAPPITLEPPAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGPPGSGPLPGPPSLSSGSGSRELLGAELRASPKAVINSQEWTLSRSIPELRLGVLGDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDGQTHLVLIREEAGAPDAKFSGWADAVIFVFSLEDENSFQAVSRLHGQLSSLRGEGRGGLALALVGTQDRISASSPRVVGDARARALCADMKRCSYYETCATYGLNVDRVFQEVAQKVVTLRKQQQLLAACKSLPSSPSHSAASTPVAGQASLast
1 -72.500d2iwra_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  98  1...................................................................................................SMRSIPELRLGVLGDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDGQTHLVLIREEAGAPDAKFSGWADAVIFVFSLEDENSFQAVSRLHGQLSSLRGEGRGGLALALVGTQDRISASSPRVVGDARARALCADMKRCSYYETCATYGLNVDRVFQEVAQKVVTLRKQQQL......................... 176
2 -61.600d3x1xa_ c.37.1.8 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  23  1.......................................................................................................MREYKLVVLGSGGVGKSALTVQFVQGIFEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDT--DDVPMILVG--NKCDLEDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDLVRQI.................................. 165
3 -60.200d3seaa_ c.37.1.8 (A:) GTP-binding protein RheB {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  22  1......................................................................................................QSKSRKIAILGYRSVGKSSLTIQFVEGQFDSADPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGK--VQIPIMLVG--NKKDLHMERVISYEEGKALAESW-NAAFLESSAKENQTAVDVFRRIILEAEK................................ 167
4 -59.700d3q72a_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  23  2.........................................................................................................VYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVDGEEASLMVYDIWEQDGGRCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQT--DDVPIILVG--NKSDLVRSREVSVDEGRACAVVF-DCKFIETSAALHHNVQALFEGVVRQIRLRR.............................. 166
5 -59.600d3c5ca_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  25  2.........................................................................................................EVNLAILGRRGAGKSALTVKFLTKRFSEYDPNLEDTYSSEETVDHQPVHLRVMDTADLDTPRYLNWAHAFLVVYSVDSRQSFDSSSSYLELLALHAKETQRSIPALLLG--NKLDMAQYRQVTKAEGVALAGRF-GCLFFEVSACLDFHVQHVFHEAVREARR................................ 167
6 -57.300d1wmsa_ c.37.1.8 (A:) Rab9a {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  27  1....................................................................................................AGKSSLFKVILLGDGGVGKSSLMNRYVTNKFDQLFHTIGVEFLKDLEVDGHFVTMQIWDTAGQERFRFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADKEPESFPFVILG--NKIDISE-RQVSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLAT............................... 174
7 -56.200d2hxsa1 c.37.1.0 (A:11-184) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  2.........................................................................................................QLKIVVLGDGASGKTSLTTCFAQETFKQYKQTIGLDFFRRITLPGNNVTLQIWDIGGQTIGGYIYGAQGVLLVYDITNYQSFENLEDWYTVVKKVSEESETQPLVALVG--NKIDLEHMRTIKPEKHLRFCQE-NGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNK........................... 174
8 -56.000d1r2qa_ c.37.1.8 (A:) Rab5a {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  23  1....................................................................................................GNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEQESTIGAAFTQTVCLDDTTVKFEIWDTAGQERYHYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPN-----IVIALSGNKADLANKRAVDFQEAQSYADD-NSLLFMETSAKTSMNVNEIFMAIAKKLPKN............................... 170
9 -55.800d1z2aa_ c.37.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  24  2.........................................................................................................AIKMVVVGNGAVGKSSMIQRYCKGIFTDYKKTIGVDFLRQIQVNDEDVRLMLWDTAGQEEFDYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVG----DIPTALVQ--NKIDLLDDSCIKNEEAEGLAKRL-KLRFYRTSVKEDLNVSEVFKYLAEKHLQ................................ 164
10 -55.500d4rkfa_ c.37.1.0 (A:) automated matches {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}  ali model 3D-neighbors follow..  20  1....................................................................................................QNFDYMFKLLIIGNSSVGKTSFLFRYADDSFSAFVSTVGIDFKKTVFRHDKRVKLQIWDTAGLERYRYYRGAMGFILMYDVTNEDSFNSVQDWVTQIKTYSW---DNAQVILVG--NKCDMEDQRVISFERGRQLADQ-LGVEFFETSAKENVNVKAVFERLVDIICDK............................... 170
11 -55.300d4d0ga_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  1......................................................................................................YSYIFKYIIIGDMGVGKSCLLHQFTEKKFADCPHTIGVEFGRIIEVSGQKIKLQIWDTAGLERFRYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPN-----TVIILIGNKADLEAQRDVTYEEAKQFAEE-NGLLFLEASAKTGENVEDAFLEAAKKIYQ................................ 167
12 -54.900d3gj0a1 c.37.1.8 (A:2-207) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  2..................................................................................................AQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKYVATLGVEVHLVFHTNRGPIKFNVWDTAGQEKFGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVC----ENIPIVLCG--NKVDIKDRKVK--AKSIVFHRK-KNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPAPEVVMDPALAAQYEHDLEVAQ 204
13 -54.300d4cyma_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  1......................................................................................................REHLFKVLVIGELGVGKTSIIKRYVHQLFQHYRATIGVDFAKVLNWDSRTVRLQLWDIAGLERFGYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHPNGSPIPAVLLA--NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQS............................ 177
14 -53.000d2p5sa_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  2..........................................................................................................YKIVLAGDAAVGKSSFLMRLCKNEFRNISATLGVDFQKTLIVDGERTVLQLWDTAGQERFRYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAH---ETVPIMLVG--NKADIEGQKCVPGHFGEKLAMT-YGALFCETSAKDGSNIVEAVLHLAREVKK................................ 170
15 -52.600d1z06a1 c.37.1.8 (A:32-196) Rab-33b {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  20  2.........................................................................................................IFKIIVIGDSNVGKTCLTYRFCAGRFDRTEATIGVDFRRAVDIDGERIKIQLWDTAGQERFRYYRNVHAVVFVYDMTNMASFHSLPAWIEECKQHLLA--NDIPRILVG--NKCDLRSAIQVPTDLAQKFADT-HSMPLFETSAKNNDHVEAIFMTLA..................................... 165
16 -51.900d2yc4c_ c.37.1.0 (C:) automated matches {Green alga (Chlamydomonas reinhardtii) [TaxId: 3055]}  ali model 3D-neighbors follow..  17  3..................................................................................................IDITATLRCKVAVVGEATVGKSALISMFTSSKFKDYAMTSGVEVVAPVTIPDTSVELFLLDTAGSDLYKYWNGVYYAILVFDVSSMESFESCKAWFELLKSARPDRERPLRAVLVA--NKTDLPPQRQVRLDMAQDWATT-NTLDFFDVSANPGKDADAPFLSIATTFYRNYEDKVAAFQDAC................... 195
17 -51.100d5c1ta2 c.37.1.0 (A:177-335) automated matches {Entamoeba (Entamoeba histolytica) [TaxId: 5759]}  ali model 3D-neighbors follow..  15  2.......................................................................................................DIKIRMLMVGDQNVGKTTFIRKFALQD-HDFMNAITTRFE----MEKIKYEIIMIDWGFYNKLLISRTIEAILIVYDITNEESFQNIHRKYYPLINNKF---SDVAGVIVG--YKTDLEAQRKITMGDALTLADWL-GYKYVEMSSKDTEDHSSIIKALAH.................................... 159
18 -51.100d5c1ta1 c.37.1.0 (A:21-176) automated matches {Entamoeba (Entamoeba histolytica) [TaxId: 5759]}  ali model 3D-neighbors follow..  16  1..........................................................................................................IRLLVVGSSGVGKTTLCDCFFESHQ-----SQGEETRKHVQIDNDFIRISISDIVGKQSFYPYDGYDAILVMYDITELKSFTDLKTWLPDIFLYCN---IDTQIIIIG--NKKDQEIDRIITRKEAEQFAQD-RLCQFYEISTKDD-SCQLLFDCISRDFLQ................................ 156
19 -42.900d1mh1a_ c.37.1.8 (A:) Rac {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  1.....................................................................................................GSPQAIKCVVVGDGAVGKTCLLISYTTNAFGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRQTDVSLICFSLVSPASFENVAKWYPEVRHH----CPNTPIILVGTKEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP.............................. 182
20 -40.800d2clsa_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  2.......................................................................................................VARCKLVLVGDVQCGKTAMLQVLAKDCYETYVPTVFENYTACLETEEQRVELSLWDTSGSPYYDNVRDSDAVLLCFDISRPETVDSAKKWRTEILDY----CPSTRVLLIGCKMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSKSIHSIFRTASMLCL................................. 179
21 -36.700d2zeja_ c.37.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  1..........................................................................................................MKLMIVGNTGSGKTTLLQQLMKTKKSMQSATVGIDVKDPIQIRDKDLVLNVWDFAGREEFYFMTQRALYLAVYDLSKGQAVDAMKPWLFNIKARA----SSSPVILVGTHDVSDEKQRKACMSKITKELLNKRGRDYHFVNATEESDALAKLRKTIINESLN................................ 176
22 -24.100d1j2ia1 c.37.1.8 (A:18-181) ADP-ribosylation factor {Human (Homo sapiens), ARF1 [TaxId: 9606]}  ali model 3D-neighbors follow..  11  1..........................................................................................................MRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVET---VEYKNISFTVWDVGGLDKIRYFQNTQGLIFVVDSNDRERVNEAREELMRM--LAEDELRDAVLLVFA--NKQDLPNAMNAAEITDKLGLHSLRHRNWQATCATSGDGLYEGLDWLSNQLRNQK.............................. 164
23 -23.000d4basa_ c.37.1.0 (A:) automated matches {Trypanosoma brucei [TaxId: 185431]}  ali model 3D-neighbors follow..  15  2.........................................................................................................KLQVVMCGLDNSGKTTIINQVKPAQSSSKHATVGYNVET---FEKGRVAFTVFDMGGAKKFRYYDNIDAVIFVVDSSDHLRLCVVKSEIQAMEDIRRELPGGGRVPFLFFANKMDAATAAELVEILDLTTLMGDHPFVIFASNGLKGTGVHEGFSWLQETASRQS.............................. 176
24 -22.900d1zd9a1 c.37.1.8 (A:17-181) ADP-ribosylation factor {Human (Homo sapiens), ARL8A [TaxId: 9606]}  ali model 3D-neighbors follow..  14  3.........................................................................................................EMELTLVGLQYSGKTTFVNVIASGQFEDMIPTVGFNMRK---ITKGNVTIKLWDIGGQPRFRYCRGVSAIVYMVDAADQEKIEASKNELHNL--LDKPQLQGIPVLVLG--NKRDLPGALDEKELIEKMNLSAIQDREIYSISCKEKDNIDITLQWLIQHSK................................. 165
25 -22.800d1f6ba_ c.37.1.8 (A:) SAR1 {Chinese hamster (Cricetulus griseus) [TaxId: 10029]}  ali model 3D-neighbors follow..  13  13.........................................................................................................TGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEE---LTIAGMTFTTFDLGGHIQARYLPAINGIVFLVDCADHERLLESKEELDSL--MTDETIANVPILILG--NKIDRPE--AISEERLREMFGNARPLEVFMCSVLKRQGYGEGFRWMAQYI.................................. 185
26 -20.600d2fh5b1 c.37.1.8 (B:63-269) Signal recognition particle receptor beta-subunit {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  16  2...........................................................................................................AVLFVGLCDSGKTLLFVRLLTGQYRDTQTSITDSSAIYKVNNNRGNSLTLIDLPGHESLRFKSSARAVVFVVDSAAQREVKDVAEFLYQVLIDSMALKNSPSLLIAC--NKQDIAMAKSAKLIQ-QQLEKELNTLRVTRSAAPSTLDSSSTFSQLPLKV.................................. 177
27 -19.200d2gj8a_ c.37.1.8 (A:) automated matches {Escherichia coli [TaxId: 469008]}  ali model 3D-neighbors follow..  14  2..........................................................................................................MKVVIAGRPNAGKSSLLNALAGREVTDIAGTTRDVLREHIHIDG--MPLHIIDTAGERAWQEIEQADRVLFMVDGTTTDAVDP----AEIWPEFIARLPAKLPITVV---NKADITGETLGM--------SEVNGHALIRLSARTGEGVDVLRNHLKQSM.................................. 161
28 -17.100d1egaa1 c.37.1.8 (A:4-182) GTPase Era, N-terminal domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  15  8............................................................................................................IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGITEGAYQAIYVDTPGKAASSSIGDVELVIFVVEGTRWTPDD------EMVLNKLREGKAPVILAV----NKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHL.................................. 170
29 -17.000d5x4ba_ c.37.1.0 (A:) automated matches {Bacillus subtilis [TaxId: 224308]}  ali model 3D-neighbors follow..  11  4...........................................................................................................VVAIVGRPNVGKSTIFNRIAGERVEDTPGVTRDRIYSSAEWLNYDFNL--IDTGGQQAEIAMDEADVIIFMVNGREGVTAADE-----EVAKILYRTKKPVVLAV----NKLDN-----TEMRANIYDFYSLGFGEPYPISGTHGLGLGDLLDAVAEHF.................................. 162
30 -17.000d1nrjb_ c.37.1.8 (B:) Signal recognition particle receptor beta-subunit {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  12  5...........................................................................................................SIIIAGPQNSGKTSLLTLLTTDSVRPTVVSQE----PLSAADYDGSGVTLVDFPGHVKLRRAKFVKGLIFMVDTVDPKKLTTTAEFLVDILSITESSCENGIDILIAC-NKSELFTARPPSKIK-DALESEIQKVIERRKKSLNEVERK............................................ 157
31 -16.900d1wf3a1 c.37.1.8 (A:3-180) GTPase Era, N-terminal domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  12  8............................................................................................................VAIVGKPNVGKSTLLNNLLGVKVAPISPRPQTTRKRLRGITEGRRQIVFVDTPGLHKYEALADVNAVVWVVDLRHPPTPED-----ELVARALKPLVGKVPILLV---NKLDAAKYP---EEAMKAYHELLPEAEPRMLSALDERQVAELKADLLALM.................................. 169
32 -16.800d1mkya1 c.37.1.8 (A:2-172) Probable GTPase Der, N-terminal and middle domains {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  13  2...........................................................................................................TVLIVGRPNVGKSTLFNKLVKKKVEDEEGVTRDPVQDTVEWYGKTFKL--VDTCGVFDLNMIREADLVLFVVDGKRGITKED-----ESLADFLRKSTVDTILVA----NKAEN-------REFEREVKPELYSLGFGEVSAEHNINLDTMLETIIKKLEEKGLD............................ 169
33 -16.600d1mkya2 c.37.1.8 (A:173-358) Probable GTPase Der, N-terminal and middle domains {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  15  1..................................................................................................SKPEITDAIKVAIVGRPNVGKSTLFNAILNKEVSPIPGTTRDPVDDEVFIDGRK--YVFVDTAGYRVVDSIEKADVVVIVLDAT-----QGITRQDQRMAGLMERRGRASVVVF----NKWDLVVHREKRYDEFTKLFREIDYSPLIFTSADKGWNIDRMIDAMNLAYASYTT............................. 186
34 -15.200d2cxxa1 c.37.1.8 (A:2-185) GTP-binding protein engB {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  11  2...........................................................................................................TIIFAGRSNVGKSTLIYRLTGKKVRR--GKRPGVTRKIIEIEWKNHKII--DMPG-VHFIEDNAKNIDVAVLVVDGKAAPEIIKRWEKRVEFYQFLRELDIPTIVAVNKDKIKNVQEVINFLAEKFEVPLSEIDKVFIPISAKFGDNIERLKNRIFEVIRER............................... 184
35 -14.600d4rd4a1 c.37.1.8 (A:2-206) automated matches {Sulfolobus solfataricus [TaxId: 273057]}  ali model 3D-neighbors follow..  13  1..................................................................................................AWPKVQPEVNIGVVGHVDHGKTTLVQAITG----IWTSKHSEELKRGMTIKKFLRRISFIDAPGHEVL--AALMDGAILVVAANEPFPQPQTREHFVALGII------GVKNLIIVQ-NKVDVVSKEEALYRQIKQFTKGAENVPIIPVSALHKINIDSLIEGIEEYI.................................. 201
36 -14.400d4ac9a4 c.37.1.8 (A:1-179) Elongation factor SelB, N-terminal domain {Methanococcus maripaludis [TaxId: 39152]}  ali model 3D-neighbors follow..  14  8............................................................................................................LGIFGHIDHGKTTLSKVLTEIASTSAHDKLPESQKRGITID-ENYRITLVDAPGHADL--ADIIDLALIVVDAKE-----------QTGEHMLILDHFNIPIIVVITKDNAGTEEIKRTEMIMKSILQSTHKNSSIIPISAKTGFGVDELKNLIITTL.................................. 173
37 -13.900d1udxa2 c.37.1.8 (A:157-336) Obg GTP-binding protein middle domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  13  4............................................................................................................VGLVGYPNAGKSSLLAAMTRAHFTTLSPNLGSEEERFTLAD-------IIEGAGLEFLRHIARTRVLLYVLDAAD-EPLKTLETLRKEVGAYDPALLRRPSLVAL---NKVDLLEEEAVKALADA----AREGLAVLPVSALTGAGLPALKEALHALVRSTPPPEM.......................... 175
38 -13.400d3w5ja1 c.37.1.0 (A:2-197) automated matches {Gallionella capsiferriformans [TaxId: 395494]}  ali model 3D-neighbors follow..  13  2...........................................................................................................RIALLGMPNTGKSTLFNRMTGGAARVGNWPGITVELLSGKILLGADMVEIIDLPGIYDLHGFSDDEQVVLALVILNATQIERQMSLLLQLKQL------NMNIVVL---NMSDEAKQYGITIDSRK--MSELLQIPVFQLSGKYGTGYQEALQAVTRALRYPTPGMA.......................... 168
39 -13.400d2lkca1 c.37.1.0 (A:5-178) automated matches {Geobacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  12  7............................................................................................................VTIMGHVDHGKTTLLDAIRHSKVTEQEAGGITQHIGAYQVTVNDKKITFLDTPGHEAFTTMRATDIVILVVAADD-----------QTVEAINHAKAANVPIIVAINKDKPEANPDRVMQELMEYNLVPEEWGTIFCKLSAKTKEGLDHLLEMIL..................................... 162
40 -13.300d2i3ba1 c.37.1.11 (A:1-189) Cancer-related NTPase, C1orf57 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  3...........................................................................................................HVFLTGPPGVGKTTLIHKASE-VLKSSGVPVDGFYTEEVRQGGRRIGFDVVTLSGTRGPLSRVGLEP----YVV-DLTSFEQLAL--PVLRNADCSSGPGQRVCVIDEIGKMELFSQLPVPKGKPLALVEEIRNRKDVKVFNVTKENRNHLLPDIVTCVQSSRK............................. 189
41 -12.800d3a1wa1 c.37.1.0 (A:17-177) automated matches {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  11  1..........................................................................................................VKVALAGCPNVGKTSLFNALTGTKQYVANWPGVTVEKKEGVFTYKGYTINLIDLPGTYSLGYSSIDEKIALVILVADSVNPEQSLYLLLEILEM------EKKVILA---TAIDEAKKTGMKIDRYE--LQKHLGIPVVFTSSVTGEGLEELKEKIVEYA.................................. 160
42 -12.300d2c78a3 c.37.1.8 (A:9-212) automated matches {Thermus thermophilus HB8 [TaxId: 300852]}  ali model 3D-neighbors follow..  11  4..........................................................................................................VNVGTIGHVDHGKTTLTAALTY-KDYGDIDKAPEERARGITIN-AKRHYSHVDCPGHADY--AAQMDGAILVVSAAD-----PMPQTREHILLARQVGVPYIVVFM----NKVDMVDDPELLDLVEMEVRDPGDEVPVIRGSALLALEQMH........................................... 175
43 -12.200d1yrba2 c.37.1.10 (A:1-245) ATP(GTP)-binding protein PAB0955 {Pyrococcus abyssi [TaxId: 29292]}  ali model 3D-neighbors follow..  12  3............................................................................................................VVFVGTAGSGKTTLTGEFLDTGVKELPYEPSIDVREFVTVEEKENDYVLIDTPGQMETFLFHEFGVRLVVYISDPEILKKPNDYCFVRFFALLIDLRLGATTIPA---NKVDLLSEGLMAYKMCSMMTEVLPPVRVLYLSAKTREGFEDLETLAYEHY.................................. 241
44 -12.000d3pr1a_ c.37.1.0 (A:) automated matches {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  12  24...........................................................................................................EVAFVGRSNVGKSSLLNALFNRKIAFVSKTPG---TRSINFYLVNSKYYFVDLPG---YGYAKVSKKLVEDY-FKNRWSLQMVFLLVDGRIPPQDSDLMNIPFTIVLTKMDKVKMSERAKKLEEHRKVFSKYGEYTIIPTSSVTGEGISELLDLISTLL.................................. 191
45 -11.900d3defa_ c.37.1.8 (A:) automated matches {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  12  6................................................................................FQQFPAATQEKLIEFFGKLKQKDMNSMTVLVLGKGGVGKSSTVNSLIGEQ-SPFQAEGLRPVMVSRTMGGFT--INIIDTPG-KGFLVNRTIDVLLYVDRLDVYAVDELDKQVVIAITQTFGKEIWCKTLLVLTHAQFSPPDEETFSSKRSDSLLKTIRAGSVYAENSGRCSKNIPNLVKAITDVATNQRKA............................ 242
46 -11.600d1g7sa4 c.37.1.8 (A:1-227) Initiation factor IF2/eIF5b, N-terminal (G) domain {Methanobacterium thermoautotrophicum [TaxId: 145262]}  ali model 3D-neighbors follow..  12  8............................................................................................................VSVLGHVDHGKTTLLDHIRGSAVASREAGICGDFLKKFSIRETLPGLFFIDTPGHEAFTTLRKADLAILIVDINEPQTQEALNILRMY----------RTPFVVA---NKIDRIQVQQKLDTKVYELVGKLSQVSIIPISAITGEGIPELLTMLMGLAQQYLREQ........................... 223
47 -11.400d2bdta1 c.37.1.25 (A:1-176) Hypothetical protein BH3686 {Bacillus halodurans [TaxId: 86665]}  ali model 3D-neighbors follow..  3...........................................................................................................KLYIIGPAGVGKSTTC-KRLAAQLDNSAYIEGDIINHMVV-ESDELLALTWKNITDLTVNFLLAQNDVVLDYIAFPDEA--------EALAQTVQAKVDDVEIRFIILWTNREELLRRDALRKKDEQMGERCLELEFESKGIDERYFYNTS-TNLNDIVKNLKTNPR.......................... 172
48 -11.300d1puia_ c.37.1.8 (A:) Probable GTPase EngB {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  12  18...........................................................................................................EVAFAGRSNAGKSSALNTLTNQKSLARTSKTPGR-TQLINLFEVADGKRLVDLPG---YGYAEVPEEALGEY-LEKRQSLQGLVVLMDIRHPLKDLDQQNIAVLVLLTKDKLASGARKAQLNMVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWF.................................. 187
49 -10.900d1f60a3 c.37.1.8 (A:2-240) Elongation factor eEF-1alpha, N-terminal (G) domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  13  1....................................................................................................GKEKSHINVVVIGHVDSGKSTTTGHLIYKKYAWVLDKLKAERERGITID-PKYQVTVIDAPGHRDF--TSQADCAILIIAGGVEAGISKDGQTREHALLAFTLGVRQLIVAV----NKMDSVKWDESRFQEIKKVGYNPKTVPFVPISGWNGDNMIE........................................... 200
50 -10.800d1svia_ c.37.1.8 (A:) Probable GTPase EngB {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  10  25...........................................................................................................EIALAGRSNVGKSSFINSLINRK----------NLARTSSKPGKTQTLNFVDVPG---YGFAKVSKSMIETY-ITTREELKAVVQIVDLRHAPSNDDVQGIPVIVIATKADKIPKGKWDKHAKVVRQTLNIDPEDELILFSSETKKGKDEAWGAIKKMINR................................ 195
51 -10.800d1ye8a1 c.37.1.11 (A:1-178) Hypothetical kinase-like protein Aq_1292 {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  1..........................................................................................................MKIIITGEPGVGKTTLVKKIVE----RLGKRAIGFWTEEVRDPETKKRTGFRIITTEGKKKIFSSKFF----YGVNVQYFEELAIPILERAYREAKKDRRK--VIIIDEIGKMELFSKKTIPIRDVHPLVKEIRRLPGAVLIELTPENRDVILEDILSLLER................................ 178
52 -10.400d4lv5b_ c.37.1.8 (B:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  39........................................................................................QLTNSAISDALKEIDSSVLNVAVTGETGSGKSSFINTLRGIGNEEEGAAKTGVVEVTMERHPNIPNVVFWDLPGIGSTNFFYEYDFFIIISATRFKKN---------DIDIAKAISMMKKEFYFV---TKVDLQDIRLNCVNTFRENGIAEPPIFLLSNKNVCHYDFPVLMDKLISDLPIYKRHNFMVSLPNITDSVIEKKRQF........ 264
53 -10.400d1qhxa_ c.37.1.3 (A:) Chloramphenicol phosphotransferase {Streptomyces venezuelae [TaxId: 54571]}  ali model 3D-neighbors follow..  13  4...........................................................................................................RMIILGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMGVSIGPEFRALEGAWAEGVVAMARAGARIIIDDVFLGGAAAQERWR----------SFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVVDTT---HKESIECAWAIAAHVV................................. 177
54 -10.100d2f1ra1 c.37.1.0 (A:4-161) automated matches {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  13  2............................................................................................................LSIVGTSDSGKTTLITRMM--------PILRERGLRVAVVKRHAHGDFEIDKEGKDSWKIYNSGADVVIASPVKLAFIRRVSEEEGNDLDWIYERYLSDYDLVITEGFSKAGKDRIVVVKKPEEVEHFRQGRILAVVCDERVDGHEVERIAEFILSLL.................................. 157
55 -10.000d1kgda_ c.37.1.1 (A:) Guanylate kinase-like domain of Cask {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  6............................................................................................................LVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRKKDEENGKNYYFVSHDQMMQSNNEYLEYGSHEDAMYG-TKLETIRKIHE--QALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTI-INNEIDETIRHLEEAVEL................................ 176
56 -9.910d3hr7a_ c.37.1.0 (A:) automated matches {Helicobacter pylori [TaxId: 85962]}  ali model 3D-neighbors follow..  17  3...........................................................................................................HLVLIGFMGSGKSSLLGLALKLEVLDTDMIISERVGLSVR--------EIFEELGEDNFRMFEKN----LIDELKTLKTPHVISTMHENLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNNLTQAKELFEKRQALYEKNASFIIDARGGLNNSLKQVLQF............................... 160
57 -9.900d1zunb3 c.37.1.8 (B:16-237) Sulfate adenylate transferase subunit cysN/C, EF-Tu domain G-like domain {Pseudomonas syringae pv. tomato [TaxId: 323]}  ali model 3D-neighbors follow..  16  4....................................................................................................HERKEMLRFLTCGNVDDGKSTLIGRLLHDDLALLVDGLQAEREQGITID-AKRKFIIADTPGHEQY--ASTCDLAIILVD-ARYGVQTQTRRHSYIASLL------GIKHIVVAI-NKMDLNGFDERVFESAEGIAFKPTTMAFVPMSALKGDNVVN........................................... 198
58 -9.820d1lw7a2 c.37.1.1 (A:220-411) Transcriptional regulator NadR, ribosylnicotinamide kinase domain {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  11  9...........................................................................................................TVAILGGESSGKSVLVNKLAAVFNTTSAWEYGREFVFEKLGGDEQAYPQMALGHQRYIDYAVRHSHKIAFI-DFITTQAFCIQGKAHPFLDSMIKEYPFDV-TILLKNNTEWVDDGLRSLGSQKQRQQFQQLLKKLLDKYKVPESPSYLDRYNQVKAVIEKVLNEEEISELQN.................... 192
59 -9.800d1xjca_ c.37.1.10 (A:) Molybdopterin-guanine dinucleotide biosynthesis protein MobB {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  13  4............................................................................................................WQVVGYKHSGKTTLMEKWV--------AAAVREGWRVGTVKHHGHGGEPARPEGVDSVRHERAGAVATAVEG-DGLLQLHLRRPLWRLDDVLALYAPLRLDLVLVEGYKQERHPKVVLVRSEEDWASLQHLANIRAVIAWEPLEGDDDEYIPWLMNEVRTR............................... 165
60 -9.680d1zp6a1 c.37.1.25 (A:6-181) Hypothetical protein Atu3015 {Agrobacterium tumefaciens [TaxId: 358]}  ali model 3D-neighbors follow..  15  7............................................................................................................LLLSGHPGSGKSTIAEALANLPGVPKVHFHSDDLWGYIK-QSHQQNRMIMQIAADVAGRYAKEGYFVIL--GVVRPDWLPAFTALARPLHYIVLRTTAAEAIERCLDRGGDSLSDPLVVADLHSQFADLGAFEHHVLPVS---GKDTDQALQSAINALQSGR.............................. 172
61 -9.620d2dy1a2 c.37.1.8 (A:8-274) Elongation factor G (EF-G), N-terminal (G) domain {Thermus thermophilus, EF-G-2 [TaxId: 274]}  ali model 3D-neighbors follow..  19  4...........................................................................................................TVALVGHAGSGKTTLTEALLTTDYTPEAKLHRTTVRTGVALLFRGHRVFLLDAPGYGDFGALEAADAALVAVSAEA-TKLDKGGDYYALLEDLRSTLGPILPIDLLYEGGKWV-----LIDVFHGKAYRYENGEEREAEVPPEERERVQRFRQEVLEAIVETDEG............................ 211
62 -9.570d2qm8a_ c.37.1.10 (A:) Metallochaperone MeaB {Methylobacterium extorquens [TaxId: 408]}  ali model 3D-neighbors follow..  12  53..........................................................................................................IRVGITGVPGVGKSTTIDALGSNAFIRPSPSSGKTRETMLLCEAAGFDVILVETVGQSETAVADLTDFFLVLMLPGAGDELQGIKKGIFELAD----------MIAV---NKADDGDGERRASAAASEYRAALHTPPVVTISGLHGKGLDSLWSRIEDHRSKLTATGEIAGKRRE................... 271
63 -9.250d3iija1 c.37.1.1 (A:1-172) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  5...........................................................................................................NILLTGTPGVGKTTLLASKSGLKYINVGDLARDEEYDCPILDEDRVVDELDNVDYHGCDFFPERWFHIVFVLRTDTNVLYERLET--------RGYNEKKL-------TDNIQCEIFQVLYEEATASYKEEI----VHQLPSNKPEELENNVDQILKWIEQWIKDHN.......................... 171
64 -9.210d3jb9b1 c.37.1.8 (B:68-451) Pre-mRNA splicing factor Cwf10, N-terminal domain {Schizosaccharomyces pombe 972h- [TaxId: 284812]}  ali model 3D-neighbors follow..  12  76...........................................................................................................SFIVAGHLHHGKSALLDLLVYYT-LRYTDTHYLERERVMSIKGKTFAFQCIDTPGHVDFVDMAISDGVVLVVDVIEGVMINTTRIIKHAILH-------DMPIVLV---NKVDILELRLPPNDAYHKLRHVIDEVN--DNICQISKDLKYRVSPELGNV.................................. 252
65 -9.170d1e6ca_ c.37.1.2 (A:) Shikimate kinase (AroK) {Erwinia chrysanthemi [TaxId: 556]}  ali model 3D-neighbors follow..  4...........................................................................................................PIFMVGARGCGMTTVLARALGYEFVDTDIFMQHTSGMTVA--------DVVAAEGWPGFRRRESTPNRVVATGVLLEQNRQFMRAHGTVV-------FAPAEELALRLQASLQAHQRPTLTGRPIAEEMEAVEREALYQDVAHYVVDATQPPAAIVCELMQTMR............................. 169
66 -9.070d1y63a_ c.37.1.1 (A:) Probable kinase LmjF30.1890 {Leishmania major [TaxId: 5664]}  ali model 3D-neighbors follow..  11  1.....................................................................................................EQPKGINILITGTPGTGKTSMA-EMIAAELDGFQHLEVGKLVKE-IIEEKDEDRLLDFMEYHSSELFPERWFHMVVVLHTSTEVLFERLTK--------RQYSEAKR-------AENMEAEIQCICEEEARDAYEDDI-----LVRENDTLEQMAATVEEIRERVEVLK.............................. 174

FFAS is supported by the NIH grant R01-GM087218-01
1 3 1 7 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Topczewski J, Godzik A., Paszewski A. The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases. Microbiology. 2000 Oct;146 ( Pt 10):2695-703.