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Query: 1aut_L mol:protein length:114 ACTIVATED PROTEIN C, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110
# Score Template Links and tools%idFirst SKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLLast
1 -50.4001aut_L mol:protein length:114 ACTIVATED PROTEIN C  ali model  100  1SKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHL 114
2 -37.9001nfu_B mol:protein length:195 COAGULATION FACTOR XA, LIGHT CHAIN  ali model follow..  38  41............DGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKL-CSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVA. 140
3 -37.9001p0s_L mol:protein length:138 Coagulation factor X precursor  ali model follow..  38  42........NKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKL-CSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTL......... 137
4 -37.1001fax_L mol:protein length:96 FACTOR XA  ali model follow..  37  2...........KDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTR-KLCSLDNGDCDQFCHEEQASVVCSCARGYTLADNGKACIPTGPYPCGKQTLER....... 96
5 -36.8001pfx_L mol:protein length:146 FACTOR IXA  ali model follow..  28  47............DGDQCEPNPCLNGGLCKDDINSYECWCQVGFEGKNCELDAT--CNIKNGRCKQFCKTGADSKVLCSCTTGYRLAPDQKSCKPAVPFPCGRVSVSHSPTTLT. 145
6 -33.7001dan_L mol:protein length:152 BLOOD COAGULATION FACTOR VIIA light chain  ali model follow..  34  46............DGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDLICVNENGGCEQYCSDHTTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNAS.. 147
7 -32.9002vj3_A mol:protein length:135 NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1  ali model follow..  25  1.......SAQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN--ECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEF. 104
8 -31.8005fm9_A mol:protein length:157 NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1  ali model follow..  18  1..........SAQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV.. 102
9 -31.4004xlw_A mol:protein length:124 Neurogenic locus notch homolog protein 1  ali model follow..  24  1..........DVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVN--ECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEF. 101
10 -30.6005fma_A mol:protein length:154 NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1  ali model follow..  19  2..............DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGEKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDV.. 99
11 -30.1004xbm_A mol:protein length:531 Delta-like protein 1  ali model follow..  23  412QAGFSGRHCDD-NVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVS--RCEHAPCHNGATCHQRGHGYVCECARSYGGPNCQFLLPELPPGPAVVDLTEKLEGQGG. 521
12 -28.1004d90_A mol:protein length:143 EGF-like repeat and discoidin I-like domain-c  ali model follow..  20  1..............DICDPNPCENGGICLPGLGSFSCECPDGFTDPNCSSVVEVGPCTPNPCHNGGTCEDTFIGYVCKCPRGFNGIHCQHNINECEVEPCKNGGICTDLVANY. 118
13 -27.5004gk9_A mol:protein length:279 agglutinin (BOA)  ali model follow..  9  38........CRSGQNVVALNIKSGDGGRTLTGTMTYVGEGPIGFRATLTQSNTYAVEGSSAPWHPGGTWVAGTMTYAGEGPIGFKSQQADGGVYAGSSAPWHNGGVWVIGARDQ. 175
14 -25.9004fbr_A mol:protein length:267 Myxobacterial hemagglutinin  ali model follow..  7  26.....GARDKQNVVA--LDIKSDDGGKTLKGTMTYNGEGPIGFRGTLSSANNYTVEGTSAPWQPGGVWVTGTTTYNGEGPIGFKSEVTDGDTYSGSAAPWHSGGVWV....... 158
15 -25.8003h5c_B mol:protein length:317 Vitamin K-dependent protein Z  ali model follow..  34  1.RYKGGSPCI--------SQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNEC-HPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGV............ 92
16 -23.6001whe_A mol:protein length:86 COAGULATION FACTOR X  ali model follow..  13  14..................ERECLEEACSLEEAREVFEDAEQTDEFWSKYKDGD--QCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKNCEFSTR..................... 86
17 -22.4004bdw_A mol:protein length:85 COAGULATION FACTOR XIIA HEAVY CHAIN  ali model follow..  17  7..............EPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQ-RLASQACRTNPCLHGGRCLEVEGHRLCHCPVGYTGPFCDVDTAA.................... 85
18 -22.2004xlw_B mol:protein length:261 Delta-like protein  ali model follow..  21  184LPGWTGKYCD---QPICLSGCHEQNGYCSK---PDECNCRPGWQGPLCN------ECIPHKGCRHGTCT---IPWQCACDEGWGGLFCDQAAA..................... 261
19 -22.1004cbz_A mol:protein length:312 PROTEIN JAGGED-1  ali model follow..  20  190MEGWMGPECNR---AICRQGCSPKHGSCKL---PGDCRCQYGWQGLYCD------KCIPHPGCVHGICNE---PWQCLCETNWGGQLCDKDLNYCGHQPCLNGGTCSN...... 283
20 -20.7002vj2_A mol:protein length:169 JAGGED-1  ali model follow..  20  50.EGWMGPECN---RAICRQGCSPKHGSCKL---PGDCRCQYGWQGLYCD------KCIPHPGCVHGICNE---PWQCLCETNWGGQLCDKDLNYCGTHPCLNGGTCSN...... 142
21 -20.6002w2m_E mol:protein length:107 LOW-DENSITY LIPOPROTEIN RECEPTOR  ali model follow..  19  13.ENLYFQGAMGTNECLDNNGGCSH--VCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACK..................... 101
22 -20.5001z1y_A mol:protein length:186 ookinete surface protein Pvs25  ali model follow..  17  1..........EAEASAVTVDTICKNGQLVQMSNHFKCMCNEGLVHLSENTCEEKNECKKETLGKENPDPAQVNMYKCGCIEGYTLKEDTCVLDVCQYKNCGESGEC........ 105
23 -19.9001emn_A mol:protein length:82 FIBRILLIN  ali model follow..  27  4............DMDECKEPDVCKHGQCINTDGSYRCECPFGYILAG-NECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGP........................... 77
24 -19.6004bxs_A mol:protein length:423 FACTOR X-LIKE PROTEASE  ali model follow..  39  42........NVYVDGDQCSSNPCHYRGICKDGIGSYTCTCLSGYEGKNCERVLYK-SCRVDNGNCWHFCKHVQNDIQCSCAEGYLLGEDGHSCVAGGNFSCGR............ 134
25 -19.4004xl1_B mol:protein length:230 Delta-like protein  ali model follow..  26  152SDNYYGDSCSRL----KKRDDHFGHYECQP---DGSPSCLPGWTGKYCDQPI----CLSGCHEQNGYCSK---PDECNCRPGWQGPLCNEAA...................... 230
26 -18.9001lmj_A mol:protein length:86 fibrillin 1  ali model follow..  30  1...TDIDECRISPDL-------CGRGQCVNTPGDFECKCDEGYEFMMMKNCMDIDECQRDPLLCGGVCHNTEGSYRCECPPGHQLSPNISAC...................... 85
27 -18.7001gl4_A mol:protein length:285 NIDOGEN-1  ali model follow..  15  1.......APLAQQTCANNRHQCSVHAECRDYATGFCCRCVANYNGRQCVAEGSPQRVNGKKGRIFVGSSQVPVVFENTDLHSYVVMNHGRSYTAISTIPSLLPLAPIGGIIGWM 115
28 -18.4003gcw_E mol:protein length:83 Low-density lipoprotein receptor  ali model follow..  20  4............GTNECLDNNGGCSYVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQ-DPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACK..................... 83
29 -18.3002bo2_A mol:protein length:143 EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE  ali model follow..  23  43....DINECATLS-----KVSCGKFSDCWNTEGSYDCVCSPGYEENTCQ-DVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTV................. 141
30 -17.1001tpg_A mol:protein length:91 T-PLASMINOGEN ACTIVATOR F1-G  ali model follow..  14  16............QQHQSWLRPVLRSNRV------EYCWCNSGRAQC---HSVPVKSCSEPRCFNGGTCQQALSDFVCQCPEGFAGKSCEIDTRAT................... 91
31 -17.0002ygq_A mol:protein length:324 WNT INHIBITORY FACTOR 1  ali model follow..  24  202PPGFYGVNCDK----ANCSTTCFNGGTCFY---PGKCICPPGLEGEQCEISKCPQPCR-----NGGKCIG---KSKCKCSKGYQGDLCSKPVCEP---GCGAHGTCHE...... 291
32 -16.8002w86_A mol:protein length:147 FIBRILLIN-1  ali model follow..  18  55.....DGRCEININGATLKSQCCSSWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCNGLCVNTRGSFKCQCPSGMTLDATGRIC...................... 146
33 -16.8003gis_X mol:protein length:121 Thrombomodulin  ali model follow..  20  38....EPHRCQLFCNQTACPADC-------DPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECICGPDSALAGQIGTDCD.................... 119
34 -16.6001uzj_A mol:protein length:162 FIBRILLIN-1  ali model follow..  25  1...........TDVNECLDPTTCISGNCVNTPGSYICDCPPDFTRVGCVILEDIDECQELPGLCGGKCINTFGSFQCRCPTGYYLNEDTRVCD..................... 162
35 -16.6003kl6_B mol:protein length:57 Coagulation Factor X light chain  ali model follow..  46  3....................................................ARKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGK............ 52
36 -16.6003v65_B mol:protein length:386 Low-density lipoprotein receptor-related prot  ali model follow..  22  1...........TGEENCNVNNGGCAQKCQMIRGAVQCTCHTGYRLTEDGRTCQDVNECAEEGYCSQGCTNSEGAFQCWCEAGYELRPDRRSCKALGPEP............... 88
37 -16.3004k0v_A mol:protein length:529 TEK tyrosine kinase variant  ali model follow..  23  190EAQKWGPECNHL-------TACMNNGVCHEDTG--ECICPPGFMGRTCEKACELRTCKQEGCKSYVFCLPDPYG--CSCATGWKGLQCNEACHPKLRCSCNNGEMCDRFQG... 306
38 -16.3002gd4_L mol:protein length:58 Coagulation factor X, Stuart factor, Stuart-P  ali model follow..  46  3......................................................KLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQT.......... 52
39 -15.8003asi_A mol:protein length:410 Neurexin-1-alpha  ali model follow..  25  182..........EGPSTTCQEDSCSNQGVCLQQWDGFSCDCSTSFSGPLCNDPGTT............................................................ 226
40 -15.8002ra0_L mol:protein length:51 Coagulation factor X  ali model follow..  50  2........................................................CSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGK............ 47
41 -15.6001f7e_A mol:protein length:46 PROTEIN (Blood Coagulation Factor VII)  ali model follow..  28  1...........SDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKD............................................................. 42
42 -15.5001hre_A mol:protein length:67 HEREGULIN ALPHA  ali model follow..  18  1.....GTSHLV-KCAEKEKTFCVNGGECLSNPSRYLCKCQPGFTGARCTENVP--MKVQNQEKAEELYQK............................................ 67
43 -15.4001kig_L mol:protein length:51 FACTOR XA  ali model follow..  58  1........................................................CSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGK............ 46
44 -15.4001dx5_I mol:protein length:118 THROMBOMODULIN  ali model follow..  22  38....EPHRCQMFCNQTACPADC-------DPNTQASCECPEGYILDDGFICTDIDECE-NGGFCSGVCHNLPGTFECICGPDSALAGQI......................... 114
45 -15.3001z6c_A mol:protein length:87 Vitamin K-dependent protein S  ali model follow..  28  2....DVDECSLKPSI-------CGTAVCKNIPGDFECECPEGYRNLKSKSCEDIDECS--ENMCAQLCVNYPGGYTCYCKKGFKLAQDQKSCEV.................... 85
46 -15.3004wm0_D mol:protein length:50 Coagulation factor IX  ali model follow..  29  3..........IVDGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCELL............................................................... 43
47 -15.0001fsb_A mol:protein length:40 P-SELECTIN  ali model follow..  25  1.............TASCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRE............................................................. 40
48 -15.0001n1i_A mol:protein length:105 Merozoite surface protein-1  ali model follow..  11  1....EAEASNMSSAHKCIDTNVPENAACYRYLGTEEWRCLLGFKGGKCVPASITCEENNGGCAPEAECTMDKKEVECKCTKEGSE............................. 85
49 -14.9002m74_A mol:protein length:136 Fibrillin-1  ali model follow..  23  61PSGQIAPSCGS-RSIQHCNIRCMNGGSCSDD----HCLCQKGYIGTHCGQPVCESGCL-----NGGRCV---APNRCACTYGFTGPQCE......................... 136
50 -14.8004yzu_B mol:protein length:62 Coagulation factor IX  ali model follow..  36  3......................................................VTCNIKNGRCEQFCKNSANKVVCSCTEGYRLAENQKSCEPAVPFPCGRVSVSQTSKLT.. 61
51 -14.2001rfn_B mol:protein length:57 PROTEIN (COAGULATION FACTOR IX)  ali model follow..  42  2.......................................................TCNIKNGRCEQFCKNSANKVVCSCTEGYRLAENQKSCEPAVPFPCGR............ 49
52 -14.1003s94_A mol:protein length:619 Low-density lipoprotein receptor-related prot  ali model follow..  30  556.......................................LMGLKATNVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIV.................... 610
53 -13.9003cfw_A mol:protein length:164 L-selectin  ali model follow..  30  104...WNDDACHKLKAALCQPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVQV............................................................. 158
54 -13.7001cej_A mol:protein length:96 PROTEIN (MEROZOITE SURFACE PROTEIN 1)  ali model follow..  22  1..........NISQHQCVKKQCPQNSGCFRHLEREECKCLLNYKGDKC-VENPNPTCNENNGGCDAKCTEEGKKITCECTKPDS.............................. 83
55 -13.7002ygo_A mol:protein length:188 WNT INHIBITORY FACTOR 1  ali model follow..  26  148..............QAECPGGCRNGGFCN---ERRICECPDGFHGPHCEGT............................................................... 181
56 -13.5001b9w_A mol:protein length:95 PROTEIN (MEROZOITE SURFACE PROTEIN 1)  ali model follow..  16  3............SEHRCIDTNVPENAACYRYLGTEEWRCLLYFKAGKCV-PAPNMTCKDKNGGCEAECKMNKNEIVCKCTKEGS.............................. 79
57 -13.4002ddu_A mol:protein length:387 reelin  ali model follow..  20  185........LDGVYISEPCPSYCSGHGDCISG----VCFCDLGYTAAQGTCVSNTPNHSEMFDRFEGKLSPL----WYKITGGQVGTGCGTLNDG.................... 262
58 -13.3001ob1_C mol:protein length:99 MAJOR MEROZOITE SURFACE PROTEIN  ali model follow..  20  1..........NISQHQCVKKQCPQNSGCFRHLEREECKCLLNYKQEGDKVENPNPTCNENNGGCDAKCTEEGKKITCECTKPDS.............................. 83
59 -13.3002kl7_A mol:protein length:71 Fibulin-4  ali model follow..  26  2....DVNECLTI------PEACKGEMKCINHYGGYLCLPRSAAV-------------INDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDS........................ 68
60 -13.2002npr_A mol:protein length:90 Merozoite surface protein 1  ali model follow..  16  4............SEHTCIDTNVPDNAACYRYLGTEEWRCLLTFKEEGGKVPASNVTCKDNNGGCAAECKMTSNKIVCKCTKEGSE............................. 81
61 -13.2001egf_A mol:protein length:53 EPIDERMAL GROWTH FACTOR  ali model follow..  26  3..........YPGCPSSYDGYCLNGGVCIESLDSYTCNCVIGYSGDRCQTRD.............................................................. 46
62 -13.1004a0p_A mol:protein length:628 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROT  ali model follow..  39  574................................................LQEYRQHPCAQDNGGCSHICLVKGGTTRCSCPMHLVLLQDELSCGGTK.................. 622
63 -13.1002mgr_A mol:protein length:99 Merozoite surface protein 1  ali model follow..  19  4....PKHVCVDT-------RDIPKNAGCRDDDGTKEWRCLLGYKKGEGNVENNNPTCDINNGGCTASCQNAESTIICTCKEPTPNA............................ 88
64 -13.1003s8v_A mol:protein length:623 Low-density lipoprotein receptor-related prot  ali model follow..  43  571................................................LQEYRQHPCAQDNGGCSHICLVKGGTTRCSCPMHLVLLQDELSC...................... 615
65 -13.0003s2k_A mol:protein length:629 Low-density lipoprotein receptor-related prot  ali model follow..  41  572................................................LQEYRQHPCAQDNGGCSHICLVKGGTTRCSCPMHLVLLQDELSCGE.................... 618
66 -12.8003ltf_D mol:protein length:58 Protein spitz  ali model follow..  21  2...FPTYKCP----ETFDAWYCLNDAHCIADLPVYSCECAIGFMGQRCEYKEIDNTYLPK...................................................... 58
67 -12.7002mgp_A mol:protein length:99 Merozoite surface protein 1  ali model follow..  20  4....PKHVCVDT-------RDIPKNAGCRDDDGTEEWRCLLGYKKGEGNVENNNPTCDINNGGCDASCQENSKKIICTCKEPTP.............................. 86
68 -12.6001yo8_A mol:protein length:634 thrombospondin-2  ali model follow..  19  1...........ADPDGCLSNPCFPGAQCSSFPGSWSCFCPVGFLGNGTH-CEDLDECALVSTSKVPRCVNTQPGFHCPCPPRYRGNQPVGVGLEAAKTECEPENPCKDKTHN.. 111
69 -12.6003soq_A mol:protein length:318 Low-density lipoprotein receptor-related prot  ali model follow..  30  262................................................RQPNATNPCGIDNGGCSHLCLMSPVFYQCACPTGVKLLENGKTCKDGNS................. 312
70 -12.5003r05_A mol:protein length:1254 Neurexin-1-alpha  ali model follow..  21  185......SPCEAGE--EGEGGVCLNGGVCSVVDDQAVCDCSTGFRGKDCSQGKEE............................................................ 231
71 -12.5001gk5_A mol:protein length:49 MEGF/TGFALPHA44-50 CHIMERA  ali model follow..  26  5............GCPSSYDGYCLNGGVCIESLDSYTCNCVIGYSGDRCEH................................................................ 44
72 -12.4005f1a_A mol:protein length:553 Prostaglandin G/H synthase 2  ali model follow..  29  2..............NPCCSHPCQNRGVCMSGFDQYKCDCTTGFYGENCSTP............................................................... 40
73 -12.1003f1s_B mol:protein length:283 Vitamin K-dependent protein Z  ali model follow..  40  1....................................................AKNECHPETDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGV............ 51
74 -11.9001dqb_A mol:protein length:83 THROMBOMODULIN  ali model follow..  21  1.......HME--PVDPCFRANCEY--QCQPNQTSYLCVCAEGFAPIPHEPHRCQMFCNQTA--CPADCDPN-TQASCECPEGYILDD........................... 74
75 -11.8001u67_A mol:protein length:600 Prostaglandin G/H synthase 1 precursor  ali model follow..  28  33.............VNPCCYYPCQHQGICVRGLDRYQCDCTTGYSGPNCTIP............................................................... 72
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.