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Query: 3cmq_A mol:protein length:415 Phenylalanyl-tRNA synthetase, mitochondrial, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKYPAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIHQALQEAAVQLLGVEGRFLast
1 -143.0003cmq_A mol:protein length:415 Phenylalanyl-tRNA synthetase, mitochondrial  ali model  100  1MAAECATQRAPGSVVELLGKSYPQDDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVNSAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKYPAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIHQALQEAAVQLLGVEGRF 415
2 -70.4001b70_A mol:protein length:350 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  27  49.KRGQELNAIKAALEAALEAREKALEEAALERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGP---------EVESEFFNFDALNIPEHHPARDMWDTFWLTGELLLRTHTSPMQVRYMVAHTPPFRIPGRVFRFEQTDATHEAVFHQLEGLVVGE-----------------------------------GIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWWGGKWLELGGAGMVHPKVFQAVDAYRVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFK........................................................................................................... 347
3 -69.8003pco_A mol:protein length:327 Phenylalanyl-tRNA synthetase, alpha subunit  ali model follow..  32  55.AAGAVINEAKEQVQQALNARKAELESAALETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGP---------EIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQPPIRIPGRVYRNDY-DQTHTPMFHQMEGLIVDT-----------------------------------NISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNKWLEVLGCGMVHPNVLRNVGIDPYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK........................................................................................................... 327
4 -68.3002rhq_A mol:protein length:294 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  29  11.RGSHMGTELMEKLNQQLAE----------ETIDVTLPSRQISIGSKHPLTRTVEEIEDLFLGLGYEIVDGY---------EVEQDYYNFEALNLPKSHPARDMQDSFYITDEILMRTHTSPVQARTMEKRNGQIICPGKVYRRDSDDATHSHQFTQIEGLVVDKN-----------------------------------IKMSDLKGTLELVAKKLFGADREIRLRPSYFPFTEPSVEVDVSCHTGWIEILGAGMVHPNVLEMAGFDSYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDVRFLEQFKAVE........................................................................................................ 284
5 -66.9004p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit  ali model follow..  30  55.KVGALINVAKEKVQDVLNARKTELEGAALERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGP---------EVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQQPPIRIPGRVYRCDS-DLTHSPMFHQVEGLLVDEG-----------------------------------VSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCQTGWLEVMGCGMVHPNVLRMSNIDPFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFR........................................................................................................... 338
6 -41.5003l4g_A mol:protein length:508 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  20  177.KGSAFSTSISKQETELSPEMISSGSWRDRPPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMG--------FTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDKNLLRTHTTSASARALYRLAQKYFSIDRVFRNETLDATHLAEFHQIEGVVADH-----------------------------------GLTLGHLMGVLREFFTKL----TQLRFKPAYNPYTEPSMEVFSYHQKKWVEVGNSGVFRPEMLLPMGLPENV-IAWGLSLERPTMIKYGINNIRELVGHKVNLQM.............................................................................................................. 486
7 -40.6002du3_A mol:protein length:534 O-phosphoseryl-tRNA synthetase  ali model follow..  13  10..........ELAEKDFEAAWKAGKEILAERSPNELYPRVGFSFGKEHPLFATIQRLREAYLSIGFSEVVNPLIVEDVHVKK-DLSYLIAEVLDVDDITAVKILDEVFPISSTLTLRSHMTTGWFITLSHIADKLFSIDRCFRREQEDATRLYTYFSASCVLVDE-----------------------------------ELSVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQTEVFASDGWIEIATFGIYSPTALAEYDIP-YPVMNLGLGVERLAMILYGYDDVRKMVYSDLDIAREIKVKEVPQTAVGLKIAQ-PAYANEVVVYKGD-GIPKTKKWRSFFEEG--VPTGIRYIDGFAYYAARKVEEAAMREQEEVKKARIVENLSDINLYIHENVRRYIKIDVR. 522
8 -36.0002du7_A mol:protein length:549 O-phosphoseryl-tRNA synthetase  ali model follow..  14  17.......KVLELAEKDFETAWRETRALIKDKHIDNKYPRLKPVYGKPHPVMETIERLRQAYLRMGFEEMINPVIV----------DEMEIYKQFGPEAMAVLD--RCFYLATTLTLRSHMTSGWFITLSSLIKKLFSIDRCFRREQRDRSHLMSYHSASCVVVGE-----------------------------------DVSVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPETQTEVYAYGEWIEVATFGVYSPIALAKYNID-VPVMNLGLGVERLAMIIYGYEDVRAFYEYRLSDRDIAGMIRVDKVPILDEFYNFPSVLNEVYVYIPPTKEQYIPILKKAKEEG--VSTNIRYIDGIIYKLVAKIEEALVSNVDEFKRVPIVRSLSDINLKIDELALKQIVIDVR. 537
9 -34.0004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  17  66.........................................YAEERENYLGKLEREITRFFVDRGFLEIKSPIL--------------------IPLEYIERMGIDNFRVDKNFCLRPMLAPNLYNYLRKDPIKIFEIGPCYRKESDGKEHLEEFTMLSFIQM-----------------------------------GSGCTRENLESIITDFLNHLGIDFKIVG--DSCMVYGDTLDVMH-----GDLELSSAVVGPIPLDREWGID-KPWIGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................ 278
10 -32.5004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  14  24.SQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQYAEERENYLGKLEREITRFFVDRGFLEIKSPILI----------PLEYIERMGIDNDTELSK--QIFRVDKNFCLRPMLAPNLGNYLRKDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQM-----------------------------------GSGCTRENLESIITDFLNHLGIDFKIVG--DSCMVFGDTLDVMH-----GDLELSSAVVGPRPLDREWGIDKP-WIGAGFGLERLLKVKHDFKNIKRAARSES-YYNGISTN......................................................................................................... 284
11 -32.3002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  15  33LNPKDEISLNSGKPFRELESELLSRRKKDLQQI--------YAEERENYLGKLEREITRFFVDRGFLEIKSPILI--------------------PLEYIERMGIDNFRVDKNFCLRPMLAPNLYNYLRKDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQM-----------------------------------GSGCTRENLESIITDFLNHLGIDFKIVG--DSCMVYGDTLDVMH-----GDLELSSAVVGPIPLDREWGIDK-PWIGAGFGLERLLKVKHDFKNIKRAARSGSYY................................................................................................................ 278
12 -32.1004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  13  6.SQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQYAEERENYLGKLEREITRFFVDRGFLEIKSPILI----------PLEYIERMGIDNDTELSK--QIFRVDKNFCLRPMVAPNIFNYARKDPIKIFEIGPCYRKESDGKEHLEEFTMLNFFQM-----------------------------------GSGCTRENLESIITDFLNHLGIDFKIVG--DSCSVYGD---TLDVM--HGDLELSSAVVGPIPLDREWGID-KPWIGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................ 260
13 -22.2003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  16  63.........................................YAEERENYLGKLEREITRFFVDRGFLEIKSPILI--------------------PLEYIERMGIDNFRVDKNFCLRPMLTPNLYNYLRKDPIKIFEIGPCYRKESDGKEHLEEFTMLVFWQM-----------------------------------GSGCTRENLESIITDFLNHL-----FKIVGDSCMVFGDTLDVMH-----GDLELSSALVGPIPLDREWGIDKPW-IGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................ 275
14 -20.9004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  14  7.SQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQYAEERENYLGKLEREITRFFVDRGFLEIKSPILI--------------------PLEYIERMGIDNFRVDKNFCLRPMLAPNLANYLRKDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQM-----------------------------------GSGCTRENLESIITDFLNHL-----FKIVGDSCMVFGDTLDVMH-----GDLELSSAVVGPIPLDREWGIDKPW--GAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................ 261
15 -15.5001b70_B mol:protein length:785 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  21  517....................................................................................................DPEDARRFRLDPPRLLLLNPLAPEKAALRTHLFPGLVRVLKENLDLDRPERALLFEVGRVFREREETHLAGLL--------------FGEGVGLPWAKERLSGYFLLKGYLEALFARL---GLAFRVEAQAFPFLHPGVSGRVLVEGEEVGFLG--ALHPEIAQELELPPV-------------------------------HLFELRLPLPDKPLAFQDPSRHPAAFRDLAVVVPAP-TPYGEVEALVREAAGPYLESLALFDLYQGPPEGHKSLAFHLRFRHPKRTLRDEEVEEAVSRVAEAL-RARGFGLR. 780
16 -15.4002rhs_B mol:protein length:800 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  18  490........................................EVTSGELTDRQHKTRTLKETLEGAGLNQAITYSLVSKDHAKDFALQERPTISLLMPMS------------EAHATLRQSLLP----------------------HLIEATAYNVARKNKDVRLYEIGRVFFGNGEGEEVEYLSGILTGEYVVNAWQGKKEEIDFFIAKGVVDRVAEKL---NLEFSYKAGKIEGLHPGRTAIVSLGGAGIGFIG---LHPQVAADNDLKRT--YVFELNYDAMM-------------------------QVAVGYINYEQIPKFPGVTRDIALEVNHD-VPSSELKQIIHNNGEDILQSTLVFDVYEHLEKGKKSVAIRLNYLDTEDTLTDERVSKIHDKILEAL-QAQGATIR. 800
17 -15.1004p71_A mol:protein length:792 Phenylalanine--tRNA ligase beta subunit  ali model follow..  15  455.................................................ISLEVDLIEELARLYGYNRLPVRYPQARLAPNNKPEARAALPLLRRLLVARGYQEAITFFIDPALFELFDPGTQPLTLANPISADMAAMRSSLWPGLVKALQHNLNRQQSRVRLFESGLRFVGQLEGKQEAMLAGAICGKRLPEGWANGRDGVDFFDAKADVEAVL-ASAGALGDFSFVPGEHPALHPGQTARIEREGRLVGYLG--ALHPELAKKLDLEQPV-FLFELLLAEVVD---------------------------GHLPKFRELSRFPEVRRDLALLV-DQDVPAQDILTQIRAAAGEWLTDLRLFDVYHGKDPHRKSLAVGLTWQHPSRTLNDDEVNSTTQNIVTSLEERFNATLR. 791
18 -14.9003pco_B mol:protein length:795 Phenylalanyl-tRNA synthetase, beta chain  ali model follow..  20  517....................................................................................................DPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNR-QQNRVRIFES--GLRFVPDTQAPLGIRQDLMLAGVICGNRYE---EHWNLAKETVDFYDLKGDLESVL-DLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVG--VVHPELERKLDLNGRT-LVFELEWNKLAD---------------------------RVVPQAREISRFPANRRDIAVVV-AENVPAADILSECKKVGVNQVVGVNLFDVYRGKAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLR. 794
19 -9.0103a5y_A mol:protein length:345 Putative lysyl-tRNA synthetase  ali model follow..  18  34..................................................AAIMAEIRRFFADRGVLEVETPC------MSQATVTDIHLVPFETRFVGPGHSQGMNLW------LMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLLQLLFTFGVEPNIGKETFVYHFPASQASLAQIST-FEVYYKGIIDQNLIEKVGMPDCSG--VALGVDRLVMLALGAETLA......................................................................................................................... 329

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.