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Query: 3l4g_A mol:protein length:508 Phenylalanyl-tRNA synthetase alpha chain, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPLCRLDAEPRPPPTQEAALast
1 -145.0003l4g_A mol:protein length:508 Phenylalanyl-tRNA synthetase alpha chain  ali model  100  1MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPLCRLDAEPRPPPTQEAA 508
2 -62.1002du7_A mol:protein length:549 O-phosphoseryl-tRNA synthetase  ali model follow..  26  4..............................................................................................................................................................................KHKRDDKMRFDIKKVLELAEKDF-ETAWRETRAKHIDNKYPRLKPVYGKPHPVMETIERLRQAYLRMGFEEMINPVIVDE--MEIYKQFGPEAMAVLD--RCFYLAGLPRPDEEKKERLREVLHLYKKGAIDGDDPEFKDLKPESTTLTLRSHMTSGWFITLSSLI-KKRKLPLKLFSIDRCFRREQRDRSHLMSYHSASCVVVGEDVSVDDGKVVAEGLLAQFGFTKFKFKPKKSKYYTPETEVYAYHPKLGEWIEVATFGVYSPIALAKYNI--DVPVMNLGLGVERLAMIIYGYEDVRAMVYPQFYEYRLSDRDIAGM............. 368
3 -60.9001b70_A mol:protein length:350 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  25  2.......................................................................................................................................LEEALAAIQNARDLEELKALKARYLGKKGLLTQEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGY-QAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLTGEGFRLEGPL------------------------GEEVEGRLLLRTHTSPMQVRYM-----VAHTPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQAL--SKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYREVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGVL................ 350
4 -60.1002rhq_A mol:protein length:294 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  30  3...............................................................................................................................................................................SSSSGLVPRGSHMGTELMEKL------QQLAEETIDVTLPSRQISIGSKHPLTRTVEEIEDLFLGLGY-EIVDGYEVEQDYYNFEALNLPKSHPARDMQDSFYITD---------------------------------------EILMRTHTSPVQARTMEK---RNGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKL--REIRLRPSYFPFTEPSVEVDVSCFKCKGWIEILGAGMVHPNVLEMAGFSNEYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDVRFLEQFKA.................. 282
5 -60.1003pco_A mol:protein length:327 Phenylalanyl-tRNA synthetase, alpha subunit  ali model follow..  26  1................................................................................................................................MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGF-TVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDT---------------------------------------TRLLRTQTSGVQIRTM-----KAQQPPIRIIAPGRVYRNDY-DQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDIRFRPSYFPFTEPSAEVDVMGKN-GKWLEVLGCGMVHPNVLRNVGIPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK................... 327
6 -59.7002du3_A mol:protein length:534 O-phosphoseryl-tRNA synthetase  ali model follow..  22  1....................................................................................................................................................................................MKFDPQKYRELAEKDF--EAAWKAGKERSPNELYPRVGFSFGKEHPLFATIQRLREAYLSIGFSEVVNPLIVEDALAVLDRCFYLATLPSKPLQEIFHRYKKGEIDGDDLSYVLDVDDITAVKILDEVFPEFKELKPISSTLTLRSHMTTGWFITLSHIA-DKLPLPIKLFSIDRCFRREQEDATRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFENFRFREKRSKYYIPDTEVFAFHPKLDGWIEIATFGIYSPTALAEYDI--PYPVMNLGLGVERLAMILYGYDDVRKMVYPQIDLDIAREIKVKEVPQTAVGLKIAQS. 383
7 -58.2004p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit  ali model follow..  24  1................................................................................................................................MENLDALVSQALEAVRHTEDVNALEQIRVHYLGKKGELTQEERPKVGALINVAKEKVQDVLNARKTELEGAALAARLAAERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGY-EVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNA---------------------------------------NMLLRTHTSPVQVRTM-----ESQQPPIRIVCPGRVYRCDS-DLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAF--LEVRFRPSFFPFTEPSAEVDIQCVICSGWLEVMGCGMVHPNVLRMSNIPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFR................... 338
8 -54.0002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  15  2.............................................................................................................................................................GSSSSGLVPRGSHMASAPALTKSQTDRLEDEISLNSGKPFRELESELLSRRKKDLQQI---YAEERENYLGKLEREITRFFVDRGFLEIKS------------PILIPLEYIERMGIDNDTE--------------------------------SKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALP-DPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMH-------GDLELSSAVVGPIPLDREWGIDK--PWIGAGFGLERLLKVKHDFKNIKRAARSGSYYNGISTN.................. 284
9 -53.0004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  15  2.............................................................................................................................................................GSSSSGLVPRGSHMASAPALTKSQTDRLEDEISLNSGKPFRELESELLSRRKKDLQQI---YAEERENYLGKLEREITRFFVDRGFLEIKS------------PILIPLEYIERMGIDNDT---------------------------------SKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALP-DPIKIFEIGPCYRKESDGKEHLEEFTMLSFIQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMH-------GDLELSSAVVGPIPLDREWGIDK--PWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTN.................. 284
10 -51.1004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  18  1..................................................................................................................................................................................PALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRYAEERENYLGKLEREITRFFVDRGFLEIKS------------PILIPLEYIERMGIDNDT---------------------------------SKQIFRVDKNFCLRPMVAPNIFNYARKLDRALP-DPIKIFEIGPCYRKESDGKEHLEEFTMLNFFQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCSVYGD-TLDV------MHGDLELSSAVVGPIPLDREWGIDK--PWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTN.................. 266
11 -48.4004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  18  2..................................................................................................................................................................................PALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDERENYLGKLEREITRFFVDRGFLEIKS------------PILIPLEYIERMGIDNDTEL-------------------------------SKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPD-PIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTLDVMH-------GDLELSSAVVGPIPLDREWGIDK--PWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTN.................. 267
12 -47.9004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  17  9........................................................................................................................................................................VPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDERENYLGKLEREITRFFVDRGFLEIKS------------PILIPLEYIERMGIDN-----------------------------------SKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALP-DPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTL-------DVMHGDLELSSAVVGPRPLDREWGIDK--PWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTN.................. 284
13 -47.7003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  17  2................................................................................................................................................................KGGLVPRGSHG----ASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRERRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKS------------PILIPLEYIERMGIDND-------------------------------TELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALP-DPIKIFEIGPCYRKESDGKEHLEEFTMLVFWQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTL-------DVMHGDLELSSALVGPIPLDREWGIDK--PWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTN.................. 281
14 -41.5003cmq_A mol:protein length:415 Phenylalanyl-tRNA synthetase, mitochondrial  ali model follow..  20  2................................................................................................................................................................................AAECATQRAPGSVVELLGKSYPQDDHSNLT--RKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDNYYLNR---------------------------------------THMLRAHTSAHQWDLLHAGLD-------AFLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKLVEFDLKQTLTRLMAHL--LEIRWVDCYFPFTHPSFEMEINFH--GEWLEVLGCGVMEQQLVNSAGAQDRI--WAFGLGLERLAMILYDIPDIRLFWCEDERFLK...................... 305
15 -15.6002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  14  11...............................................................................................................................................................RGSHMFLTRRDPPLSSFWTKVQYQRLKELNASGEQLEMGFSDALSRDRAFQGIEHQ---RTVKHRPALLELEEKLAKALHQQGFVQVVTPTIITK-----SALAKMTIGEDHPLFSQVFWLD--------------------------------------GKKCLRPMLAP-NLYTLWRELERLWDKPIRIFEIGTCYRKESQGAQHLNEFTMLNLTELPLEERHQRLEDMARWVLEAAGIREFELVTESSVVYGDTVDVMKGD------LELASGAMGPHFLDEKWEIFD--PWVGLGFGLERLLMIREGTQHVQSSYLDGVRL........................ 299
16 -12.0003l4g_B mol:protein length:589 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  12  195.......CELMNIYKTDNHLKHYLHIIENKPL-YPVIYDSNGVVLSMPPIIN----DHSRITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEY----------ENQFTVEAAEVVFPNGKSHTFPELAYRKEMVRADLINKKVGIRETP--ENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYNNIQ------MTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQE--IADKLGVDI-----SATKAVHISNPKTAE-----------------------------------QVARTTLLPGLLKTIAA--NRKMPLPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYV----KASEGPAFFPGRCAEISVGKLGVLHPDVITKFEL--TMPCSSLEINIGPFL........................................... 589
17 -10.4004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  10  1...........................................................................................................................................................MGSSSSGLVPRGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHS------------MGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRA------QLEKSGYLKSFPNLLGCVCGLHGTEREINAAVSRFDAGGD------------WTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREP-HLDRLQSFRMREYVCIGTP-FRERWMVRAQAIARDLGL-TFRVDYASDPFQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHAFGMDRLAFHTHGTDLVRDILG............................. 325
18 -10.3003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  11  47.....................................................................................................................................................................................................................SDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRA--QLEKSGYLKSFP----NLLGCVCGLHGTEREINAAVSRFDAGGD------------WTTSLSPADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREP-HLDRLQSFRMREYVCIGTP-FRERWMVRAQAIARDLGL-TFRVDYASDPFQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGEPAHAFGMDRLAFHTHGTDKVRDILGLQ........................... 327
19 -9.8401z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subu  ali model follow..  14  1....................................................................................................................................................................................................MRGSGSIEGRMEKINYLLPSAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMP--------------------PSFEYTQLYTALESNGKTFNQEKM-------------------FQFIKHEGQSITLRYDFTLPLVRLYSQIKDS---TSARYSYFGKIFRKEKRHKGRSTENYQIELFGESADKSELEILSLALQVIEQLGLNKTV-------------------------FEIGSAKFFQ..................................................................... 180
20 -9.5203ica_A mol:protein length:213 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  11  7...................................................................................................................................................................................................................................YKWQTVVSEQLVGAGFNEILNNSLTAGSYY--------EGLKSHPREMAVELMNPLSQEL----------------------------------NCMRQTLLFGGLETL-SHNLRRKHLSLYLFEWGKCYRFHAAKRTDYAEDDRLGIWICGEPTSVFELKAVVEQVLCRVGIETGAY---TLKTADNDLYASAMEVKTRSGKLLGTFGTVSTELIKRFEIEQPV........................................................ 202

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 5 2 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.