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Query: 3l4g_B mol:protein length:589 Phenylalanyl-tRNA synthetase beta chain, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKEIISKEQGNVKAAGASDVVLYKIDVPANRYDLLCLEGLVRGLQVFKERIKAPVYKRVMPDGKIQKLIITEETAKIRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIENKPLYPVIYDSNGVVLSMPPIINGDHSRITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEYCENQFTVEAAEVVFPNGKSHTFPELAYRKEMVRADLINKKVGIRETPENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYVIKASEGPAFFPGRCAEIFARGQSVGKLGVLHPDVITKFELTMPCSSLEINIGPFLLast
1 -178.0003l4g_B mol:protein length:589 Phenylalanyl-tRNA synthetase beta chain  ali model  100  1MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKEIISKEQGNVKAAGASDVVLYKIDVPANRYDLLCLEGLVRGLQVFKERIKAPVYKRVMPDGKIQKLIITEETAKIRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIENKPLYPVIYDSNGVVLSMPPIINGDHSRITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEYCENQFTVEAAEVVFPNGKSHTFPELAYRKEMVRADLINKKVGIRETPENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYNNIQMTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISATKAVHISNPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPPGEDKGGYVIKASEGPAFFPGRCAEIFARGQSVGKLGVLHPDVITKFELTMPCSSLEINIGPFL 589
2 -88.1002cxi_A mol:protein length:348 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  31  1MPKFDVSKSDLERLIGRSFSIEEWEDLVLYAKCELDDVWEE---------------NGKVYFKLDSKDTNRPDLWSAEGVARQIKWALGIEKGLPKYEVKKSN--VTVYVDEKLKDIRPYGVYAIVEGLRLDEDSLSQMIQLQEKIALTFGRRRREVAIGIFDFDKIKPPIYYKAAEKTE-KFAPLGYKEEMTLEEILEKHEKGRE---YGHLIKDKQFYPLLIDSEGNVLSMPPIINSEFTRVTTDTKNVFIDVTGWKLEKVMLALNVMVTALAERGGKIRSVRVVY----KDFEIETPDLTPKEFEVELDYIRKLSGLELNDGEIKELLEKMMYEVEI--SRGRAKLKYPAFRDDIMHARDILEDVLIAYGY....................................................................................................................................................................................................................... 348
3 -77.3002rhs_B mol:protein length:800 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  17  103...IKIKRAKLRRSEGMICSLQEIGISSNVVPKAYENGIFVFPTEVEPGTDALTALYLNDQVMEFDLTPNRADALSMVGTAYEVAALYQTETKPETQSNETSESATNLSVTIDNPEKVPYYSARVVKNVSIEP----SPIWVQARLKAGIRPINNVVDISNYVLLEYGQPLHMFDQDHIGSKEIVVRQAKD--EETMTTLDNNERKLVDTDIVISNGQEFSEVTEQTTNVVIEGAIFDPVSIRHTSRRLNLRSEEKGIATEFVDEAVDRACYLLQELASGEVLQDRVSS--------GDLGSFVTPIDITAEKVNKTIGFNLSNDEIQSIFRQLGFETTL--KGETLTVNVPSRRKDITIKEDLIEEVARIYGYDEIPSSLPVEVTSGELTDRQHKTRTLKETLEGAGLNQAITYSLVSKDHAKDFA---LQERPTISLLMPMSEAHATLRQSLLPHLIEATAYNVARKNKVRLYEIGRVFFGNGEGEL-PDEVEYLSGILTGEEIDFFIAKGVVDRVAEKLNLE-------FSYKAGKIEGLHPGRTAIVSLGGAGIGFIGELHPQVAADNDLK-RTYVFELNYDAMM 695
4 -73.8001b70_B mol:protein length:785 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  17  101...QKVGERVIQRSFGMALSPRELGVG------EYGGGLLEFPEDALPPGTPLSEAWPEEVVLDLEVTPNRPDALGLLGLARDLHALGYALVEPEAALKAEALP-LPFALKVEDPEGAPHFTLGYAFGLRVAP----SPLWMQRALAAGMRPINNVVDVTNYVMLERAQPMHAFDLRGEGIAVRRAREGER-----LKTLDGVERTLHPEDLVIAGGGAESEVREDTEAIALEVACFDPVSIRKTARRHGLRTEERGVDPLGQVPAQRRALSLLQALAGARVAEALLEAGSPK---------PPEAIPFRPEYANRLLGTSYPEAEQIAILKRLGCRVE--GEGPTYRVTPPSHRLDLRLEEDLVEEVARIQGYETIPLALPAFFPARGVEAPYRKEQRLREVLSGLGFQEVYTYSFMDPEDARRF----RLDPPRLLLLNPLAPEKAALRTHLFPGLVRVLKENLDLDRPALLFEVGRVFRER--------EETHLAGLLFGRLSGYFLLKGYLEALFARLGLA-------FRVEAQAFPFLHPGVSGRVLVEGEEVGFLGALHPEIAQELELP-PVHLFELRLPLPD 679
5 -71.9003pco_B mol:protein length:795 Phenylalanyl-tRNA synthetase, beta chain  ali model follow..  17  99LPDFKIKAAKLRPSEGMLCSFSELGIS------DDHSGIIELPADAPIGTDIREYLKLDDNTIEISVTPNRADCLGIIGVARDVAVLNQLPLVQPEIVPVGATIDDTLPITVEAPEACPRYLGRVVKGINVKAP---TPLWMKEKLRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRGGIVVRMAKEGET-----LVLLDGTEAKLNADTLVIADHNKHSGVNDETQNVLLECAFFSPLSITGRARRHGLHTDERGVDPALQHKAMERATRLLIDICGGEAGPVIDITNEAT---------KRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVT--EGKDEWQAVAPSWRFDMEIEEDLVEEVARVYGYNNIPDEPVQASIMGTHREADLSLKRVKTLLNDKGYQEVITYSFVDPKVQQMI----HPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNVRIFESGLRFVPDTQAPLGIRQDLMLAGVICGETVDFYDLKGDLESVLDLTGKL-----NEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVFELEWNKLA 690
6 -71.8004p71_A mol:protein length:792 Phenylalanine--tRNA ligase beta subunit  ali model follow..  18  98LPDFKIKKAKLRESFGMLCSAKELQIS------EENAGLLELPADAPVGQDVRTYLELADYTIEVGLTPNRGDCLSLAGLAREVSAIYDVPLAPVAVDAVAAQHDETRPVELAAPAACPRYLGRVIRNVDLSRP---TPLWMVERLRSDIRSIDPVVDVTNYVMIELGQPMHAFDLAEGGVRVRMAEDGEK-----LVLLDGQEITLRADTLVIADHQRHSGVSDSTRDLFLEAAFFDTIALAGKARSYGLHTDERGVDSQLARKAMERATRLILDIVGGEPGPIVEQVSEAH---------KVAPITLRAERVTQMLGMPLDAAEIVRLLQALELTVVADGEG-QWSVGVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARAPNNKPEARAALPLLRRLLVARGYQEAITFSFIDPALFELF----DPGTQPLTLANPISADMAAMRSSLWPGLVKALQHNLNRQQSVRLFESGLRFVGQLE---GLKQEAMLAGAICGDGVDFFDAKADVEAVLASAGAL-----GDFSFVPGEHPALHPGQTARIEREGRLVGYLGALHPELAKKLDLEQPVFLFELLLAEVV 687
7 -50.7003ig2_A mol:protein length:213 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  18  1...................................................................................................................................................................................................................................................................................................................................................................................................SNADKSNKLQNLVAEQLVGCGFNEILNNSLTRAAYYDGL--ESYPSKNLVMLLNPLSADLNCMRQTLLFGGLESIAHNANRKNALKFFEFGNCYHFDAEKKNPYSEDYHLGLWVTGENTSVYELKAYVENIFKRLGLD-----LHSLVVGNLSDDIYSTALTVNTKGGKRLATFGVVTKKMLKAFDVDNEVYYADLNWKELM 213
8 -49.6003ica_A mol:protein length:213 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  17  1...................................................................................................................................................................................................................................................................................................................................................................................................SNADRRYKWQTVVSEQLVGAGFNEILNNSLTAGSYYEGL--KSHPREMAVELMNPLSQELNCMRQTLLFGGLETLSHNLRRKHLLYLFEWGKCYRFHAAKRTAYAEDDRLGIWICGEPTSVFELKAVVEQVLCRVGIE-----TGAYTLKTADNDLYASAMEVKTRSGKLLGTFGTVSTELIKRFEIEQPVYFAELLWDALM 213
9 -21.3004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  13  1.............................................................................................................................................................................................................................................................................................................................MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFLESELLSRRKKDLQQIYAE----ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIER---MGIDNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMV----------GDTLDVMHGDLELSSAVVGPRPLDREWGIDKPWIGAGFGLERLL 259
10 -21.1004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  13  1...............................................................................................................................................................................................................................................................................................................................MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSG-LESELLSRRKKDLQQIYAE----ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG---IDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRAPDPIKIFEIGPCYRKESDGKEHLEEFTMLSFIQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMV----------GDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLL 259
11 -20.8002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  13  1...............................................................................................................................................................................................................................................................................................................................MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSG-LESELLSRRKKDLQQIYAE----ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG---IDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRAPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMV----------GDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLL 259
12 -20.1004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  13  32............................................................................................................................................................................................................................................................................................................................................................................LESELLSRRKKDLQQIYAE----ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIER---MGIDNDTELSKQIFRVDKNFCLRPMVAPNIFNYARKLDRAPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFFQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCSV----------GDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLL 241
13 -18.8003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  15  66...................................................................................................................................................................................................................................................................................................................................................................................................ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG---IDNDTELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRAPDPIKIFEIGPCYRKESDGKEHLEEFTMLVFWQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMV----------GDTLDVMHGDLELSSALVGPIPLDREWGIDKPWIGAGFGLERLL 256
14 -17.7004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  15  42.........................................................................................................................................................................................................................................................................................................................................................................................KKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG---IDNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRAPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMV----------GDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLL 242
15 -13.2002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  13  18..........................................................................................................................................................................................................................................................................................................TRRDPPLSSFWTKVQYQRLKELNASGEQLEMGFSDAL-----SRDRAFQGIEHQLMSQGKRHLEQLRTV---------------------HRPALLELEEKLAKALHQQGFVQVVTPTIITKSALAKM---TIGEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWREERLWDKPIRIFEIGTCYRKESQGAQHLNEFTMLNLTELGTPLEHQRLEDMARWVLEAAGIR------EFELVTESSVVY--GDTVDVMKGDLELAS-GAMGPHFLDEWEIFDPWVGLGFGLERLL 275
16 -12.2002rhq_A mol:protein length:294 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  14  18..........................................................................................................................................................................................................................................................................................................................................................................ELMEKLNQQLAEETIDVTLPRQISIGSKHPLTRTVEEIEDLFLGLGYEIVDGYEVEQDYYNFEALNLPKSHPARDMQDSFYITDEILMRTHTSPVQARTMEKRNGQG-PVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKLFGADREIRLRPSYFPFTEPSV-KGKGCNVCKHTGWIEILGMVHPNVLEMAGFDSNEYAFGMGPDRIA 257
17 -12.0001b70_A mol:protein length:350 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  13  24...........................................................................................................................................................................................................................................................................................................................RYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIK--EAREKALEEAALKEALER----ERVDVSLPASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHTGEGFRLEGPLGEEVELLRTHTSPMQVRYMVAHT----PFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQAL-----GPDSKVRFQPVYFPFVEPGAQFAVWWPEELGGA-GMVHPKVFQAVDAYRERLGLPPAYRGV. 310
18 -12.0003l4g_A mol:protein length:508 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  12  8..................................................................................................................................................................................................ELLLRRLEASDGGLDSAELAAELGMHQAVVGAVKSLQALGEVIE-STKHWELTAEGEEIAREGSHEARVFRSIPPEGLAQSEL-SKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKEKERSELRKRKLLAEVTLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESS-NFDALFQPQDQHDTFFLRDPAEAL-NLLRTHTTSASARALYRQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYN-PSMEVFSYHQGLKKWV-----EVGNSGVFRPEMLLPMGLNVSVIAWGLSLERPT 465
19 -11.3003pco_A mol:protein length:327 Phenylalanyl-tRNA synthetase, alpha subunit  ali model follow..  12  30...........................................................................................................................................................................................................................................................................................................................EYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAK--NARKAELESAALNARLAA----ETIDVSLPRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQ----PIRIIAPGRVYRNDYDQ-THTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNF-----EEDLQIRFRPSYFPFTEPSAEVDVMGKNEVLGC-GMVHPNVLRNVGIDPEVYAFGMGMERL. 302
20 -9.9604p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit  ali model follow..  11  30...........................................................................................................................................................................................................................................................................................................................HYLGKKGELTQVMKTLGDLP-----AEERPKVGALINVAKEKVQDVLN-GAALAARLAAERIDVTLPRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQQ----PIRIVCPGRVYRCDSDL-THSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAF---------EKQLEVRFRPSFFPGNGCRVCKQTGWLEVMGMVHPNVLRMSNIDPEKFAFGMGAERL. 313
21 -9.8002du3_A mol:protein length:534 O-phosphoseryl-tRNA synthetase  ali model follow..  14  44...................................................................................................................................................................................................................................................................................................................................................................................................GKEHPLFATIQRLREAYLSIGFSEVVNPLIVEDVHVKKQFGREALIAEVLDVDDITASSTLTLRSHMTTGWFITLSHADKLPLPIKLFSIDRCFRREQGEDTRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFE----NFRFRKDEKRSKYYIPDTQTEVFA---EIATFGIYSPTALAEYDIPYPVMNLGLGVERLA 334

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Godzik A. NERD: a DNA processing-related domain present in the anthrax virulence plasmid, pXO1. Trends Biochem Sci. 2004 Mar;29(3):106-10.