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Query: 3qh0_A mol:protein length:610 Prostaglandin G/H synthase 2, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQDPQPTKTATIAASASHSRLDDINPTVLIKRRSTELLast
1 -162.0003qh0_A mol:protein length:610 Prostaglandin G/H synthase 2  ali model  100  1MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLIMKYVLTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDSKEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNHIYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQFLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLNEYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETMVELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSFNVQDPQPTKTATIAASASHSRLDDINPTVLIKRRSTEL 604
2 -144.0005f1a_A mol:protein length:553 Prostaglandin G/H synthase 2  ali model follow..  88  2..................NPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPD.................................. 553
3 -143.0001u67_A mol:protein length:600 Prostaglandin G/H synthase 1 precursor  ali model follow..  61  16LLSPSPVFSADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRPSPSFIHFLLTHGRWLWDFVNA-TFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYAQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHFHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATLKKLVCLNTKTCPYVSFHVP---DPRQEDRPGVE----RPPTEL........... 600
4 -95.5002o86_A mol:protein length:595 Lactoperoxidase  ali model follow..  17  11...............................................................................................................PLVKCDENSPYRTITGDCNNRALARWLPAYEDGLALPFGWTNGFRVPLAREVSNKIVGLDEDGVLDQNRSLLFMQWGQIVDHDLDFAYQSLAREQINAVTSFLDASLVYGSEPSLASRLQNLSSPLGLMAVDHGLAYLPFNNRKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPQWDGEKLYQEARKILGAFVQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFT-FAFRFGHMEVPSTVSRLDENYPLHTLFFNTRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWEN---PGVFTEK-QRDSLQKMSFSRLICDNT-HITKVPLHAFQANNYPHDFVDCSA----VDKLDLSPWASREN... 595
5 -95.3002ikc_A mol:protein length:595 milk lactoperoxidase  ali model follow..  18  11...............................................................................................................PLVKCDENSPYRTITGDCNNRALARWLPAYEDGLAVPFGWTNGFRVPLAREVSNKIVGLDEEGVLDQNRSLLFMQWGQIVDHDLDFAYQSLARDQINSVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVDHGLAYPPFNNMKPSPCEFINTTARVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPRYQGYNNSVDPRISNVFT-FAFRFGHMEVPSTVSRLDENYPLHTLFFNTRIIKDGGIDPLVRGLLAKKSKLMNQNKMVTSELFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQANKILAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWEN---PGVFTEK-QRDSLQKVSFSRLICDNT-HITKVPLHAFQANNYPHDFVDCSA----IDKLDLSPWASREN... 595
6 -95.2002e9e_A mol:protein length:595 Lactoperoxidase  ali model follow..  18  11...............................................................................................................PLVTCDEQSPYRTITGDCNNRALARWLPAYEDGLAVPFGWTNGFRVPLAREVSNKIVGLDEEGVLDQNRSLLFMQWGQIVDHDLDFAYQSLARDQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVDHGLAYPPFNNVKPSPCEFINTTAHVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEMLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFT-FAFRFGHMEVPSTVSRLDENYPLHTLFFNTRIIKDGGIDPLVRGLLAKNSKLMNQNKMVTSELFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQANKVLAKKLLDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWEN---PGVFTEK-QRDSLQKVSFSRLICDNT-HITKVPLHAFQANNYPHDFVDCSA----VDKLDLSPWASREN... 595
7 -94.8002ips_A mol:protein length:595 Lactoperoxidase  ali model follow..  17  11...............................................................................................................PLVKCDENSPYRTITGDCNNRALARWLPAYEDGLALPFGWTNGFRVPLAREVSNKIVGLDEEGVLDQNRSLLFMQWGQIVDHDLDFAYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFT-FAFRFGHMEVPSTVSRLDENYPLHTLFFNTRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWEN---PGVFTEK-QRDSLQKVSFSRLICDNT-HITKVPLHAFQANNYPHDFVDCST----VDKLDLSPWASREN... 595
8 -94.3004hhr_A mol:protein length:652 Alpha-dioxygenase  ali model follow..  20  23.................................................HKDFHEIYARMSLLDRFLLLIVHGVDKMVPWHKLPVFLLTYLEVRRHLHQQYNLLNVGQTPTGIRFDPANYPYRTADGKFNDSFFGRNCPPVDQK--------SKLRRPDPMVVATKLLGRKKFIDTGKQFNMIAASWIQFMIHDWIDHLEEIKTGSQNIRTPWWDSSVIYGSNSKTLDRVRTYKDGKLKISEETGLLLHD----------------EDGLAISGDIR-NSWAGVSALQALFIKEHNAVCDALKDEDDDLEDEDLYRYARLVTSAVVAKIHTIDWTVQLLKTDTLLAGMRANWYPQNHGVPYSLTEDFTSVYRMHSLLPDQLHILDKSLPLIQEISMRDLISHIGFTKLMVSMGHQASGAL-ELMNYPMWLVDLAALEIYRDRERSVPRYNEFRRSMFMIPITKWEDLTEDEEAIEVLDDVYGDVEELDLLVGLMAEKKIKGFAISETAFYIFLIMATRRLEADRFFTSDF-NETIYTKK-GLEWVNTTESLKDVIDRMTDKWMNSESAFSVWDSPPLTKNPIPLYLRIPS.............. 645
9 -90.8004kvj_A mol:protein length:621 Fatty acid alpha-oxidase  ali model follow..  19  8.................................................HPDLRDVFSKMSFFDKIGFLFIHAFDKRNLWHKVPVPILLYLNTRRTLLEKYNLLAVGRSSHGALFDPKEFLYRTEDGKYNDTFFGRNMEPVD--------QQDELMSPDPFVVATKLLARREYKDTGKQFNILAAAWIQFMVHDWMDHMEDTGIGHYNIRTAWWDGSAVYGNNEERAEKLRTYVDGKLVI---GDDGLLLH--------------KENGVALSGDIR-NSWAGVSILQALFVKEHNAVCDAIKEEHPNLSDEELYRYAKLVTSAVIAKVHTIDWTVELLKTKTMRAAMRANWYGNNHGVPYSLTEEFTSVYRMHSLIPSTLKLRDPTGQPDAGLKGEEQLSKIGFEKQALSMGYQACGALE-DGTNRSDRIDLAALEVYRDRERSVPRYNEFRRRLFLIPIKSWEDLTSDKDAIETIRAIYGDVEKLDLLVGLMAEKKIKGFAISETAFNIFILMASRRLEADRFFTSNF-NEETYTKK-GMQWVKTTEGLRDVINRITAKWMKSSSAFSV................................. 610
10 -81.8003f9p_C mol:protein length:467 Myeloperoxidase  ali model follow..  16  43.....................................................................................................................................................................................................GSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNGLLAVNQRNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYPTYRSYNDSVDPRIANVFT-NAFRYGHTLIQPFMFRLDNRYPLSRVFFASRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEILDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWEN---EGVFSMQ-QRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCST----LPALNLASWREAS.... 467
11 -23.5003f9p_A mol:protein length:114 Myeloperoxidase  ali model follow..  16  2..................................................................................................................TCPEQDKYRTITGMCNNRAFVRWLPAYEDGFSLPYGWTNGFPVALARAVSNEIVRPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVT........................................................................................................................................................................................................................................................................................................................................................................................................... 113
12 -11.6004bdw_A mol:protein length:85 COAGULATION FACTOR XIIA HEAVY CHAIN  ali model follow..  27  40............CQRLASQACRTNPCLHGGRCLEVE-GHRLCHCP-VGYTGPFCDVD................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 82
13 -10.9001tpg_A mol:protein length:91 T-PLASMINOGEN ACTIVATOR F1-G  ali model follow..  30  41..........AQCHSVPVKSCSEPRCFNGGTCQQAYFSDFVCQCP-EGFAGKSCEI.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 86
14 -10.1001aut_L mol:protein length:114 ACTIVATED PROTEIN C  ali model follow..  27  9............CLVLPLEHPCASLCCGHGTCID-GIGSFSCDCR-SGWEGRFCQRE................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 51
15 -9.2101fax_L mol:protein length:96 FACTOR XA  ali model follow..  40  2...............KDGDQCETSPCQNQGKCKD-GLGEYTCTCL-EGFEGKNCELF................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 41
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.