current user: public

Please be advised that we have recently moved our server to a new location. We tried our best to fully test all functions on the website, but if something does not work for you please let us know.

Query: 4p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit, from PDB1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .
# Score Template Links and tools%idFirst MENLDALVSQALEAVRHTEDVNALEQIRVHYLGKKGELTQVMKTLGDLPAEERPKVGALINVAKEKVQDVLNARKTELEGAALAARLAAERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQQPPIRIVCPGRVYRCDSDLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNIDPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFRLast
1 -125.000[J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit  ali follow..  53  3.EQLEALRDDAIKKIEQAQEKKVVQEIRVKYLGKKGPVTEVLRGMGKLSPEERPVIGQLANDVREAIGKAIESKMEALEQAEIHRKLQEETIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKGPIKIICPGKVFRRDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGMVHPRVLEMSGFNPNEYSGFAFGMGVERLSMLKYGIDDIRHFYTNDRRFLAQFK 342
2 -97.100[J] KOG2784 Phenylalanyl-tRNA synthetase, beta subunit  ali follow..  22  172.FKWVSVDKGRVVRQATEVTDSTRKQLESLRIGSSDVSENEKKELKKSEVNIKALVVSKGTSFTTSLAKQEADLTPEMIASGSWKDMQFKKYNFDSLGVVPSSGHLHPLMKVRSEFRQIFFSMGFSEMTNRYVESSFWNFDALFQPQQHPARDAHDTFFVSDPAISTKFPEDYLERVKTVHSRPSKLFSIDRVFRNETDATHLAEFHQVEGVIAEKNLSLAHLIGIFTEFFKKLGIT--NLRFKPTYNPYTEPSMEIFAYH----------QGLTKWVEIGNSGMFRPEMLLPMGL-PADVNVAGYGLSLERPTMIKYGINNIRDLFGSKIDLNVVYN 544
3 -71.800[J] COG2024 Phenylalanyl-tRNA synthetase alpha subunit (archaeal type)  ali follow..  17  3.FDPQKYRELAEKDFEAARSPNELYPRVGFSFGKEHPLFATIQRLREAYLSIGSEVVNPLIVEDVHVKKQFGREALAVLDRCFYLATLPKPNVGISAEKIRQIEAITKREVDSKPLQEIFHRYKKGEIDGDDLS--YLIAEVLDVDDITAVKILDEVFPISSTLTLRSHMTTGWFITLDKLPLPIKLFSIDRCFRREEDATRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQTEVFAFHPKLVGSSTKYSDGWIEIATFGIYSPTALAEYDIP---YPVMNLGLGVERLAMILYGYDDVRKMVYPQIHGEIKLS 358
4 -65.500[J] KOG2783 Phenylalanyl-tRNA synthetase  ali follow..  25  2.......................................................FPHRVSHLSKLFSRRFPNWKRKVQTDSWSN---VPEHIHSKIGRNLFQKEGHPICSLRQLLEQQFQKFEMNNVKESPIVSVETNFDSLGFPKTHVSRSKSDTYYMNNKTCLRTHTSAHQPEEFKEGFKKNGFLITADVYRRDEDSSHYPIFHQMEGALVWNRNDTAKMKNDLKKVALSPSLKSMVDDETTALETHNDMQDIYSLFPFTKPSFQLEIDWKGKWLEILGCGVVQDRLLKGAGL--NNYIGWAFGIGLERLAMILYGIPDIRLFWSLDERFSKQFL 328
5 -12.000[J] COG0017 Aspartyl/asparaginyl-tRNA synthetases  ali follow..  11  5IKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSK-NEVIRATYEFFNKDGFTKVDPPILTAS----------APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHG---KVFSFGPTFRAEKSKTHLIEFWMIEGEMA---TNHAESLEIQEQYVTHVVKS-IANHYDLPVFITNYPTKIKPFYMQPNPELCADLIAPEGYGEIIGGSELLEQRVKEHGLDEEAYSYYGFGLGLERTVAWISGVEHVRET............ 418
6 -11.900[J] KOG0554 Asparaginyl-tRNA synthetase (mitochondrial)  ali follow..  11  118VRTLRSQSSVTFIEINDGSCLSNLQCVMTSDAEGYDQTGASVSVQGTIVASQGTKQKVELKVEKIIVVGECDSSYPIQKKRVSREFLRTKAHLRPRTNTFGAVARVR--NTLAYATHKFFQESGFVWVASPIITAS---FCVTTLIPSSHENTDTSI-FFGKPAFLTVSGQLNGETYATALS---DVYTFGPTFRAENSNTHLAEFWMIEPELA---ADLDDDMACATAYLQYVIIRDYPKEIKAFYMRENDDGKTVAAMDMLVPRIG----------ELIGGSQREERLLDELKLNKESYWWYGFGLGFERLVQFVTGIDNIRDV............ 555
7 -11.700[J] KOG0555 Asparaginyl-tRNA synthetase  ali follow..  10  144......VLRDGYGFLQCVLNDKLCQSYDAVTLSTETSVQVYGIIKALPDGKSAPDGHELTVDYWEVIGKAPAGGIDNVLNESAGVDVMLDNRHLVIRGENASR------AAATRAMRDHFFAAGYTEVAPPTLVQT----------QVEGGSTLFGLDYYGEPAYLTQSSQLYLETCNAALG---DVYCISQSYRAEKSRTHLSEYQHVEAECA---ITFDQLMDRIEALVCDTVDRFVNPGYKAPARPFKRMPYKEAIEWLQKNDVRNEMGEKFVY-EIVGGSM---AAFEKGGLDSKNYYWYGYGLGLERFICWLTDTNHIRDV............ 533
8 -10.400[J] KOG0556 Aspartyl-tRNA synthetase  ali follow..  141.VNKDTISKQMVKWCGSISLESIVLVEGIVKKSPEIIKSATVQDA-EIHISSIYVISPIKKNLPFLVEDAIRESEENAAEGDSKFVRVNLDTRLDNRVLDLRTPTNQAIAGICQAFREFLLSNSFNEIHTPKMSGA----------SSEGGSNVFKIQYFKTDGFLSQSPQLYKQMLIAADRE--RVFEIGPVFRAEDSNTHMTEFTGLDLEMAFNE-HYHEVMEFIEKLFLYIF-KTIREKYAKQV-DRIRFHFKDAVKLLKEAGYRKQLVPGQK--EIMSGAQLLVERMKALGVSPDV----GGGIGLERVVMFYLNLPNIRLA............ 568
9 -10.200[J] KOG2472 Phenylalanyl-tRNA synthetase beta subunit  ali follow..  12  285IEPVEVTYDDGKSYIYPDLAVYDMEVPLSFITDSIGVSLKVEQVTSLLTRMQLQAEQAKSSDNQCAIKVHVPPSRSDVLHPCDVMEDVAIAYGFNIPTRKPASIKPLTLNELTDLLRIEIAMCVYTEVVTWLLCSHKENFAMLNREDVNSAVIVGNPR--ADFEAMRRALMPGLLKTVGHNNKPIKIFEISDVVLDESKDVGASNRRHLAALYCGATSGFELIHGLVDRIMEVMAIPFLTIHENNVPINEKD-YVKLSQEPEFLPGRQASIIVRGK--HIGNFGIVHPEVLNNFDI---PDPCSYLELDIEAIL........................ 598
10 -9.830[J] COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II)  ali follow..  14  44.............................................................................................................ATLLRQIREFFAERNVLEVETPAMSHA--HLHTFKTEFVGPGYAKGSALHL------MTSPEFHMKRLLAAGSG--CIYQLGKAFRNENGRYHNPEFTMLEWYRIGFDHHMDEMDALLQLVLRCGSAERMTYQLQLLFSIGIEPKIGQIAFVYDFPASQAALAKINP-FEVYFKGIIDYHLIAALEAGLPECAGV--ALGIDRLIMLALGEDHIDKV............ 341

FFAS is supported by the NIH grant R01-GM087218-01
1 2 9 7 3 7   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.