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Query: 4p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit, from PDB1018

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MENLDALVSQALEAVRHTEDVNALEQIRVHYLGKKGELTQVMKTLGDLPAEERPKVGALINVAKEKVQDVLNARKTELEGAALAARLAAERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQQPPIRIVCPGRVYRCDSDLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNIDPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFRLast
1 -127.000IDP90648 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Vibrio cholerae O1 biovar eltor str. N16961] VC1219 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  64  1MQHLQEIIANATSAINAAESLVALDEVRVQYLGKKGELTVQLQSLGKLPPEERRTAGQEINVAKEAVQKALAERKDALQSAELEAKLAAETIDVTLPGRRIENGGLHPVTRTIERIESFFGELGFTVESGPEIEDDFHNFDALNIAADHPARTDHDTFFFNPKLMLRTHTSGVQIRTLEERQPPLRFIAPGRVYRNDYDQTHTPMFHQVEGMLVDENVNFAQLKGILHDFLCNFFEEDLEVRFRPSYFPFTEPSAEVDVK-----------GKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK 327
2 -125.000IDP04618 phenylalanyl-tRNA synthetase subunit alpha [Bacillus anthracis str. Sterne] BAS4456 [Bacillus anthracis str. Sterne]  ali follow..  55  3.ARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLDDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKGPIKIICPGKVYRRDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFK 342
3 -125.000IDP90652 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0897c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  48  1.......MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKELEDEAKKEFAAKLNAQKEIFNEAYLAKFKDLENLALEERMKQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSIEKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLRTQTSPVQIRTMLAQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSVEDFLRYMFGDVKVRFRPSFFPFTEPSAEVDISCVFCKGKGCRVCKHTGWLEVLGCGIVDPNVYNFVGY--ENVSGYAFGLGVERFAMLLHQIPDLRSLFEGDLRLLEQFR 330
4 -124.000IDP05680 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Listeria monocytogenes EGD-e] lmo1221 [Listeria monocytogenes EGD-e]  ali follow..  52  2LEQLQTLKSEAETQINEASDLKTLNDLRVKYLGKKGPMTEIMKQMGKLSAEERPKMGSLANEVRTALTEAISSKQQILETEAINEKLKSETIDVTLPGTAPSIGTKHLLTQVIEEMEDMFIGMGYEIAEGPEVELDYYNFEALNLPKDHPARDMQDSFYITENTLLRTQTSPVQMEKHDFSKGPIKVICPGKVYRRDNDATHSHQFTQIEGLVVGENITFADLKGTLTVLAKTMFGEEREIRLRPSFFPFTEPSVEMDISCFKCGGKGCRVCKGTGWIEILGSGMVHPNVLEMSGIDSTRYSGFAFGLGPERVAMLKYAVDDIRHLYTNDLRFTKQFQ 343
5 -123.000IDP90756 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Yersinia pestis CO92] YPO2429 [Yersinia pestis CO92]  ali follow..  66  1MPHLAELVAKAKAAVEGAQDIAALDLVRVEYLGKKGHLTLQMTSLRELPAEERPAAGAVINQAKQEVQEALNARKEKLESAVLNARLAAETIDVSLPGRRMENGGLHPVTRTIERIETFFGELGFSVESGPEIEDDYHNFDALNIPAHHPARADHDTFWFDATRLLRTQTSGVQIRTMQEQQPPIRIIVPGRVYRNDYDQTHTPMFHQMEGLIVDRDISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVM-----------GKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK 327
6 -122.000IDP90931 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Salmonella typhimurium LT2] STM1337 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  67  1MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVM-----------GKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 327
7 -120.000IDP90840 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Shigella flexneri 2a str. 2457T] S1634 [Shigella flexneri 2a str. 2457T]  ali follow..  67  1MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVM-----------GKNGKWLEVLGCGMVHPNVLRNVSIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK 327
8 -120.000IDP06044 gene: pheS; phenylalanyl-tRNA synthetase subunit alpha [Helicobacter pylori J99] NP_223695 [Helicobacter pylori J99]  ali follow..  43  1.......MHTLIERLEKVTNSKELEEARLNALGKKGVFADKFNQLKNLNGEEKNAFAKEIHHYKQAFEKAF-ELKKKAIMELELEERLKKEKIDVSLFNAIKTSSSHPLNYTKNKIIEFFTPLGYKLEIGSLVEDDFHNFSALNLPPYHPARDMQDTFYFKDHKLLRTHTSPVQIHTMQEQTPPIKMICLGETFRCDYDLTHTPMFHQIEGLVVDQKGNIRFTHLKGVIEDFLYFFGGVKLRWRSSFFPFTEPSAEVDISCVFCKQEGCRVCSHTGWLEVLGCGMVNNAVFEAIGY--ENVSGFAFGMGIERLAMLTCQINDLRSFFETDLRVLESF. 328
9 -91.100IDP92038 phenylalanyl tRNA synthetase isoform, putative [Toxoplasma gondii ME49] TGME49_034500 [Toxoplasma gondii ME49]  ali follow..  23  152.TLLDVIQGQRDGNQDDAAALFKQLSELTATASPEKALQDLKKRKLVELRKVKYLKLQKGPKFSLHLMKPVADLTAELLIGDAWEKSNFKEYNFFAAGKRIRRGAVHPLMQVMKQFKQILYCMGFEEMPNQYVESSFWCFDSLFMPQQHPARDVQDTFFLQAPKILRTHTTASSARMLYGLARPRKFFSIDRVFRNETDATHLAEFHQVEGLVADRGLTIGHLMGVMETFYKQIGIE--QLKFKPAYNPYTEPSMEIFGY----------HAGLKRWIEVGNSGIFRPEMLLPMGL-PEDVTVIAWGLSLERPTMIRYGISNIRQLFGHRALL..... 522
10 -12.500IDP05333 aspartyl-tRNA synthetase [Bacillus anthracis str. Sterne] BAS2031 [Bacillus anthracis str. Sterne]  ali follow..  12  27VKKIRHLGNVSFLLLRDRTGVIQC--LENEFAGFKVDVESIVHVIGEIVETSKTELGVEVLAHEVKILNGAEPLPFEINKKKLQVGLDQLLNERVLSLRHERTTAIFKVSTLVQSFSELLIENDFTRIFTPKIVSQ----------GAEGGANVFKLPYFQKEAYLAQSPQFYKQMMVAGGLE--RVFEIAPVYRAEHHNSHLNEYISLD-VELGFIHDFHEVMQLETDVLRYMFQQEKELQLLQIEVPVITEIPKITLYPKEARPMYTMPNNENSAIEITSGAQMLLDSFKEKGLHPDKFQSYGFGIGLERIVYKLLELSNVREA............ 420
11 -12.200IDP05569 asparaginyl-tRNA synthetase [Bacillus anthracis str. Sterne] BAS4454 [Bacillus anthracis str. Sterne]  ali follow..  14  27IRNLRDSKAFGFIELNDGSFFKSVQIVFDTELDNFKEIAKLPLSVKVEGKVIATPGAKQPFEIKAEKIDIEGLSDSDYPLQKKRHTFEYLRTIAHLRPRTNAFSATFRVSIAAFAIHQFFQERGFVHVHTPIITGS---FRV-NVPKGEDGQVDESKDFFGKETNLTVSGQLNAEAYALAFR---DVYTFGPTFRAENSNTHAAEFWMVEPEIA---AELGDVMNLTEDMLKYAMKYVLEKDIKAFYMRLNDDGKTVAATDLLVPGIG----------ELIGGSQVLVDRIKELGMNEEDYWWYGFGLGFERFLMYITGMANIRDV............ 451
12 -12.200IDP05209 gene: asnC; asparaginyl-tRNA synthetase [Staphylococcus aureus subsp. aureus COL] SACOL1494 [Staphylococcus aureus subsp. aureus COL]  ali follow..  11  5IKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSK-NEVIRATYEFFNKDGFTKVDPPILTAS----------APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHG---KVFSFGPTFRAEKSKTHLIEFWMIEGEMA---TNHAESLEIQEQYVTHVVKS-IANHYDLPVFITNYPTKIKPFYMQPNPELCADLIAPEGYGEIIGGSELLEQRVKEHGLDEEAYSYYGFGLGLERTVAWISGVEHVRET............ 418
13 -11.600IDP90728 gene: asnC; asparaginyl-tRNA synthetase [Yersinia pestis CO92] YPO1412 [Yersinia pestis CO92]  ali follow..  15  26VRTRRDSKAGIS-AVYDGSCFDPLQAVVNNTLPLHLTTGCSVEVTGTVVASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWVSTPLITAS-STLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALS---KVYTFGPTFRAENSNTHLAEFWMVEPEVA---ASLDDVAGLAEKMLKYVFQAVLNKDIKAFYMRMNEDGKTVAAMDVLAPGIG----------EIIGGSQREERLLAEMGLNKEDYWWYGFGLGFERLISYVTGVQNVRDV............ 454
14 -11.600IDP90531 RecName: Full=Asparaginyl-tRNA synthetase; AltName: Full=Asparagine--tRNA ligase; Short=AsnRS Q9KSF9 [Vibrio cholerae]  ali follow..  13  6VNDVLSGKLAVDSEVTVRGWIRTRRDSKAGISFLAIYDGSCFNPIQAVVPNNLNNYDNEVLKLTTGCSVEVTGKIVESPASGQAFELAASDVKVVGWVEDADTYPMAKTNCLAQAIHRFYHEQGYFWVSAPLITAS-STLDMENLPRTDAGKVDYNQDFFGKETFLTVSGQLNAEAYACAIS---KVYTFGPTFRAENSNTHLAEFWMVEPEVA---ADLNTVAKLAEDMLKYVIVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIG----------EIIGGSQREERLMREFGIDPEHMDWYGFGLGFERLVSYVTGMGNVRDV............ 454
15 -11.600IDP05239 gene: ansB; asparaginyl-tRNA synthetase [Listeria monocytogenes EGD-e] lmo1896 [Listeria monocytogenes EGD-e]  ali follow..  11  5INQASEFVGKEVTIGAWLANKRSSGKIAFLQLRDGTGFMQGVVVKAEVGDDIFATAGTINEDTRSPFGYEMAVSSVEVISESHDYPITPKEHGTEFLMDHRHLWLRSN-NEIIRASYEFFNKEGFLKIDPPILTGS----------APEGTTELFHTKYFEEDAFLSQSGQLYMEAAAMAFG---KVFSFGPTFRAEKSKTHLIEFWMIEPEMA---YKLEDSLQVQENYVAFLVKA-IADSFEKPVFITHYPKAIKPFYMPEDPELCADMIAPEGYGEIIGGSERIHDLMEDFDLDQEAYSWYGFGLGLERTVAWISGTEHVRET............ 418
16 -9.880IDP05307 lysyl-tRNA synthetase [Yersinia pestis CO92] YPO0362 [Yersinia pestis CO92]  ali follow..  16  20.............................................................................................................AAIMAEIRRFFADRGVLEVETPTMSQA--HLVPFETRFVGPGAADGLTLYM------MTSPEYHMKRLLAAGSG--PIYQLGRSFRNEAGRYHNPEFTMLEWYRPHYDMYMNEVDDLLQQILDCNSAETLSYQLQLLFTVGVEPYIGRDAFIYHFPASQASLAEIST-FEVYFKGIIDMNLIAALKQGLPDCSGV--ALGVDRLVMLALNAERLSDV............ 317
17 -9.660IDP01693 gene: yjeA; lysyl-tRNA synthetase [Salmonella typhimurium LT2] STM4344 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  20.............................................................................................................AAIMAEIRRFFADRGVLEVETPCMSQA--HLFPFETRFVGPGHSQGINLYL------MTSPEYHMKRLLAAGCG--PVFQLCRSFRNEMGRHHNPEFTMLEWYRPHYDMYMNEVDDLLQQVLDCQPAESLSYQLQLLFTMGVEPHIGKETFIYHFPASQASLAQIST-FEVYYKGIIDQNLLDALAAGLPDCSGV--ALGVDRLVMLALGAESLADV............ 317

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sasin JM, Godzik A, Bujnicki JM. SURF'S UP! - protein classification by surface comparisons. J Biosci. 2007 Jan;32(1):97-100.