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Query: 5YW3 Entity 1(prereleased), from PDB1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120
# Score Template Links and tools%idFirst ADFEVHMLNKGKDGAMVFEPASLKVAPGDTVTFIPKDKGHNVETIKGMIPDGAEAFKSKINENYKVTFTAPGVYGVKCTPHYGMGMVGVVQVGDAPANLEAVKGAKNPKKAQERLDAALAALGNLast
1 -16.700sp|P00450|CERU_HUMAN(removed signalp:1-19) Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1  ali   20  193............NGRMFGNLQGLTMHVGDEVNWYLMGMGHTVYKHRGVYSSDVFDIFPGTYQTLEMFPRTPGIWLLHCTDHIHAGMETTYTVLQNEDTKSG....................... 296
2 -15.500sp|P12259|FA5_HUMAN(removed signalp:1-28) Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4  ali   12  207............NGYVNGTMPDITVCAHDHISWHLLGMSNGQVLEQNHHKVSAITLVSATSTTANMTVGPEGKWIISSPKHLQAGMQAYIDIKN.............................. 300
3 -15.500sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   17  45............NGKLYANLRGLTMYQGERVAWYMLAMGHTIYRNGENYRADVVDLFPGTFEVVEMVASNPGTWLMHCTDHVHAGMETLFTVFSRTEHLSPLTVIT.................. 153
4 -15.400sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   18  195............NGKLYANLRGLTMYQGERVAWYMLAMGHESFLYRNGENYRADVVDLFPGTFEVVEMSNPGTWLMHCTDHVHAGMETLFTVFSRTEHLSPLT..................... 300
5 -15.100sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   15  47............NGKIFGNLHGLIMNEDTMTNWYLLGIGHTIFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLLHCSDHIHAGMETTYTVLRNIDN.......................... 147
6 -14.900sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   15  18.............NGYVFDSLQLSVCLHEVAYWYILSIGSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCSDFRNRGMTALLKVSSCDKNTGD....................... 117
7 -14.700sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   11  169GTFRIPRPRTGPEEHLGILGPLIKGEVGDILTVVFKNNPYSVHAHGVLESTTVWPLAAEPGEVVTYQWNACVSWIYYSAVDMYSGLVGPLAICQKGILEPHGGRSDMDRE.............. 297
8 -14.700sp|P00450|CERU_HUMAN(removed signalp:1-19) Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1  ali   14  171STFRVPVERKAEEEHLGILGPQLHADVGDKIIFKNMATRPYSIHAHGVQTESSTVTPTLPGETLTYVWSACIPWAYYSVKDLYSGLIGPLIVCRRPYLKVFNPRRK.................. 294
9 -14.700sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   15  197............NGKIFGNLHGLIMNEDTMTNWYLLGIGHTIFKIDKSYREDVYDLFPGTFQTIELFADHPGTWLLHCSDHIHAGMETTYTVLRNIDN.......................... 297
10 -14.400sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   17  151............NGFLFSNLPRLDMCKGDTVAWHLLGLGQGNTVQLQGMRKGAAMLFPHTFVMAIMQPDNLGTFEIYCGSHREAGMRAIYNVSQCPGHQATPRQRY.................. 256
11 -14.100sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   12  85............NGYVNRSLPGLIGCHRKSVYWHVIGMGEGHTFLVRNHRQASLEISPITFLTAQTLLMDLGQFLLFCSSHQHDGMEAYVKVDSCPEEPQLRMKNN.................. 190
12 -14.000sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   14  169GEFVEIKARPPREEHLELLGPMIHAEVGNTVLIIFKNKAQGVEEMDSG--KQFQVPMTKPGEVKTYRWNIPIPWVYYSTVNFYSGLMGPLITCRKGVLNEKGRRSDVDYE.............. 300
13 -13.600sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   16  167............INGYVFDSLQLSVCLHEVAYWYILSIGSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWILGCSDFRNRGMTALLKVSSCDKN.......................... 264
14 -13.000sp|P12259|FA5_HUMAN(removed signalp:1-28) Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4  ali   11  112............NGYVPESITTLGFCFDDTVQWHFCSVGTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTSSSPRSKKLRLKFRDVKCIPDDDEDSYEIFEPPESTVMAT....... 228
15 -12.700sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   15  151............NGYMYGNQPGLNMCKRDRVSWHLIGLGQGNTIHLRGTHRDSLALFPHMATTAFMQPDHAGIFRVFCMPHLSRGMGQIYEVSSCDNRDPSEQRYG.................. 256
16 -12.700sp|P00450|CERU_HUMAN(removed signalp:1-19) Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1  ali   18  155............NGFMYGNQPGLTMCKGDSVVWYLFSAGSGNTYLWRGERRDTANLFPQTSLTLHMWPDTEGTFNVECTDHYTGGMKQKYTVNQCRRQSEDST..................... 257
17 -12.600sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   15  98............NGYLFGNFPEPDMCVGESVSWHLFGMGHSIYFYGNTFGHRTDVVNLFPATFLTTEMENPGKWMITCSDHLQAGMLGQYNVDNCKSD.......................... 195
18 -12.400sp|P00450|CERU_HUMAN(removed signalp:1-19) Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1  ali   15  76...................P-IIKAETGDKVYVHLKNLAHGITYPDNTTDFQRADDKVYPGEQYTYMLLATVTRIYHSPKDIASGLIGPLIICKKDSLDKEKEK.................... 192
19 -12.400sp|P00450|CERU_HUMAN(removed signalp:1-19) Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1  ali   15  94............NGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHAAFFNYRIDTINLFPATLFDAYMQNPGEWMLSCLNHLKAGLQAFFQVQE.............................. 187
20 -12.300sp|P12259|FA5_HUMAN(removed signalp:1-28) Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4  ali   12  57............NGYVNGTMPDITVCAHDHISWHLLGMSNGQVLEQNHHKVSAITLVSATSTTANMTVGPEGKWIISSPKHLQAGMQAYIDIKNCPKKTRNLKKIT.................. 162
21 -12.200sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   16  74...................P-TIQAEVYDTVVITLKNMAVGVSYWKAS-QREKEDDKVFPGGSHTYVWQVLLTYSYLSVKDLNSGLIGALLVCREGS........................... 183
22 -12.100sp|P12259|FA5_HUMAN(removed signalp:1-28) Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4  ali   12  118...................P-IIRAEVDDVIQVRFKNLAHGLSYEDDSPEWFKEDNAVQPNSSYTYVWHATRAWAYYSEKDIHSGLIGPLLICQKGILHKD....................... 231
23 -11.600sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   21  135...................P-VIRAEVGDTIQVVFYNRAHGVFYEKDY--SSYPGLVAKPFEKVTYRWTVPLTWMYFSIRDTNSGLVGPLLVCRAGA........................... 241
24 -11.500sp|P12259|FA5_HUMAN(removed signalp:1-28) Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4  ali   12  93...................P-IIRAQVRDTLKIVFKNMAHGVTFSPYEDEVNSSFTSGQPGETYTYKWNILLTRPYYSMRDIASGLIGLLLICKSRS........................... 202
25 -11.400sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   10  111...................P-YIRAEVEDNIMVTFRNQASLISYEEDQ--AEPRKNFVKPNETKTYFWKVQKAWAYFSEKDVHSGLIGPLLVCHTNT........................... 212
26 -11.400sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   23  135...................P-VIKAEVGDTLLVTFANKAHGVIYDKAS-GFVKPGAHVKPGETFTYKWTVPLTYLYFSAVDTSSGLVGPLLVCKKGV........................... 241
27 -11.300sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   16  78...................P-VLQAEVGDVILIHLKNFAHGVFYEKDS--PLKADDSVPPGGSHIYNWTIPLTWIYHSPRDIATGLIGPLITCKRGA........................... 187
28 -11.300sp|P40259|CD79B_HUMAN(removed signalp:1-28) B-cell antigen receptor complex-associated protein beta chain OS=Homo sapiens GN=CD79B PE=1 SV=1  ali follow..  3SEDRYRNPKGSACSRIWQSPRFIARKRGFTVKWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQ-EDNGIY--FCQSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLI..... 141
29 -11.000sp|Q96BF3|TMIG2_HUMAN(removed signalp:1-22) Transmembrane and immunoglobulin domain-containing protein 2 OS=Homo sapiens GN=TMIGD2 PE=1 SV=2  ali follow..  15  6..................GPNLLQVRQGSQATWTKDGAINGSLSLGVCGPQGRLSWQAPSHLTLPVSLNHSGAY--VCWAEEAEGNITRLFVDPDDPTQNRNRIASFPGFLF............ 131
30 -10.900sp|Q6MZM0|HPHL1_HUMAN(removed signalp:1-24) Hephaestin-like protein 1 OS=Homo sapiens GN=HEPHL1 PE=2 SV=2  ali   16  78...................P-ILRAEVGDVIVIHLKNFAHGVFYPDGTSGRNKNDDMVPPGKNYTYVWPVRLTWVYHSPKDICSGLIGPLLVCKEGI........................... 187
31 -10.800sp|Q9BQS7|HEPH_HUMAN(removed signalp:1-23) Hephaestin OS=Homo sapiens GN=HEPH PE=2 SV=3  ali   14  99............NGFVFGNLPELNMCAQKRVAWHLFGMGHGQMLTTRGHHTDVANIFPATFVTAEMVPWEPGTWLISCNSHFRDGMQALYKVKS.............................. 192
32 -10.700sp|P00450|CERU_HUMAN(removed signalp:1-19) Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1  ali   16  112ASFTNRKERGPEEEHLGILGPVIWAEVGDTIRVTFHNKGIGVRFNKNN-SVPPSASHVAPTETFTYEWTVPLAKMYYSTKDIFTGLIGPMKICKKGS........................... 245
33 -10.400sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   17  151...................P-LLYGEVGDTLLIIFKNQAHGITDVRPL--KHLKDFPILPGEIFKYKWTVTLTRYYSSERDLASGLIGPLLICYKES........................... 258
34 -10.200sp|P09564|CD7_HUMAN(removed signalp:1-25) T-cell antigen CD7 OS=Homo sapiens GN=CD7 PE=1 SV=1  ali follow..  12  1............AQEVQQSPHCTTVPVGASVNITCSTSGGLRDGVVPTTDRRFRGRIDFSGSQDNLTITMHRL-TYTCQAITEVNVYGLVLVTEEQSQGWHRCSDAPPRASA............ 126
35 -10.000sp|P98161|PKD1_HUMAN(removed signalp:1-23) Polycystin-1 OS=Homo sapiens GN=PKD1 PE=1 SV=3  ali   14  1......ICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNISAANLVEVQEP............................. 92
36 -9.980sp|Q15116|PDCD1_HUMAN(removed signalp:1-24) Programmed cell death protein 1 OS=Homo sapiens GN=PDCD1 PE=2 SV=3  ali follow..  14  5.........DRPWNPPTFSPALLVVTEGDNATWYRMSPSNQTDRSQPGQDCRFRVTQLPNGRDFHMSVNDSGTY--LCGAISLASLRAELRVTERRAEVPTAHPSPSPRPAGQFQT........ 144
37 -9.860sp|P12259|FA5_HUMAN(removed signalp:1-28) Coagulation factor V OS=Homo sapiens GN=F5 PE=1 SV=4  ali   12  9...........EDDSPEWFKEDNAVQPNSSYTYVWH-----ATERSGPESPG----------------SACRAWAYYSAVDIHSGLIGPLLICQKGILHKD....................... 81
38 -9.730sp|P01815|HV202_HUMAN Ig heavy chain V-II region COR OS=Homo sapiens PE=1 SV=1  ali follow..  17...TLTLTCTFSGFSLSSTGMCVG-PPGKGLEWLARIDWDDDKYYNTSLETRLTISKDTSRNQVVLTMDPVDTATYYCARITVIGRGTPVTVSS.............................. 120
39 -9.590sp|Q86WI1|PKHL1_HUMAN(removed signalp:1-20) Fibrocystin-L OS=Homo sapiens GN=PKHD1L1 PE=2 SV=2  ali   15  23.RITNNGKDSVHGLGYAWSPPVLNVSVGDTVAWHWQTHPFLRGIGYRIFSVSSPG-QKSTSGSFSYQFTSPGIHYYYVDEAHSIFLQGVINVLPAET........................... 133
40 -9.300sp|Q9H106|SIRPD_HUMAN(removed signalp:1-29) Signal-regulatory protein delta OS=Homo sapiens GN=SIRPD PE=2 SV=2  ali follow..  14  6..................TEMSQTVSTGESIIWFKGTGPNRYNFKQGNFPRVKEIGDTTKPGNTDFSTADAGTY--YCVKFIKSGRGTQVFVTEQNPRPPKNRPAGRAGSRAHHDA........ 134
41 -9.280sp|Q7Z6A9|BTLA_HUMAN(removed signalp:1-30) B- and T-lymphocyte attenuator OS=Homo sapiens GN=BTLA PE=1 SV=3  ali follow..  14  12..................RQSEHSILAGDHVTWCKLNGTTCVKLEDRQTSWKEEKNISFFILHFPVLPNDNGSY--RCSANFQSNLI-TLYVTDVKSASERPSKDEMASRPWLLY......... 126
42 -9.280sp|P00451|FA8_HUMAN(removed signalp:1-19) Coagulation factor VIII OS=Homo sapiens GN=F8 PE=1 SV=1  ali   18  1..................EPRKNFVKPNETKTYFWK-----VQHHMAPTKDEFDC----------------KAWAYFSDVDLHSGLIGPLLVCHTNTLNPAHGRQVT................. 72
43 -9.050sp|P01732|CD8A_HUMAN(removed signalp:1-21) T-cell surface glycoprotein CD8 alpha chain OS=Homo sapiens GN=CD8A PE=1 SV=1  ali follow..  10  1.............SQFRVSPLDRTWNLGETVEWLFQPRGAKPKAAEGLDTQRFSGKRLGDTFVLTLSFRRENEGYYFCSALSNFSHFVPVFLPAKPTTTPAPRPPTPAPTIASQ.......... 134

FFAS is supported by the NIH grant R01-GM087218-01
1 3 5 1 7 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.