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Query: 5Z4P Entity 6(prereleased), from PDB1018

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MYTFVVRDENSSVYAEVSRLLLATGQWKRLRKDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELSESCTWFPESYVIYPTNLKTPVAPAQNGIRHLINNTRTDEREVFLAAYNRRREGREGNVWIAKSSAGAKGEGILISSEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRTSSEPYNSANFQDKTCHLTNHCIQKEYSKNYGRYEEGNEMFFEEFNQYLMDALNTTLENSILLQIKHIIRSCLMCIEPAISTKHLHYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDVAISSVFPLADTGQKTSQPTSIFIKLLast
1 -123.000sp|Q8NG68|TTL_HUMAN Tubulin--tyrosine ligase OS=Homo sapiens GN=TTL PE=1 SV=2  ali follow..  88  1MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQLVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEPAISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFPPPDVE-QPQTQPAAFIKL 377
2 -84.100sp|O95922|TTLL1_HUMAN Probable tubulin polyglutamylase TTLL1 OS=Homo sapiens GN=TTLL1 PE=2 SV=1  ali follow..  20  8.........VTDIEKSVLINNFEKRGWVQV-TENEDWNFYWMSVQTIRNVFAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGS--LYLDFVPVTYMLPADYNLFVEEF---------------------RKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKEAYVISLYINNPLLI--GGRKFDLRLYVLVSTPLRCYMYKLGFCRFCTVKYTPSELDNMFVHLTNVAIQKHGEDY--NHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDK---HCFECYGYDIIIDDKLKPWLIEVNASPSLTTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSP..... 370
3 -83.200sp|Q3SXZ7|TTLL9_HUMAN Probable tubulin polyglutamylase TTLL9 OS=Homo sapiens GN=TTLL9 PE=2 SV=3  ali follow..  20  47.........KTTLMNTLMDVLRHRPGWVEV-KDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREKLEAAKCDFFPKTFEMPCEYHLFVEEF---------------------RKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTVENYVAQRYIENPYLI--GGRKFDLRVYVLVMSAECLLWS---------------GHRRQDVHLTNVAVQKTSPDYHPK--KGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDK---HCFELYGYDILIDQDLKPWLLEVNASPSLTSQEDYELKTCLLEDTLHVV-DMEARLTGREKRVGGFDLM 387
4 -80.500sp|A6PVC2|TTLL8_HUMAN Protein monoglycylase TTLL8 OS=Homo sapiens GN=TTLL8 PE=1 SV=3  ali   26  1....................................................................................................................................SVNPQTDIDGLRNIWIIKPAAKSRGRDIVCMDRVEEILELAASRDNKWVVQKYIETPLLIC--DTKFDIRQWFLVTDPLTIWFYKESYLRFSTQRFSL-DKLDSAIHLCNNAVQKYLKNDVGRSPAHNMWTSTRFQEYLQRQGRGAVWSVIYPSMKKAIAHAMKVAQDHVEPRK---NSFELYGADFVLGRDFRPWLIEINSSPTMSTPVTAQLCAQVQEDTIKVAV-------DRSCDIGNFELL 246
5 -77.500sp|Q6ZT98|TTLL7_HUMAN Tubulin polyglutamylase TTLL7 OS=Homo sapiens GN=TTLL7 PE=2 SV=2  ali   26  1............................................................................................................................................KRKQKTFIVKPANGAMGHGISLIRNGDKL-----PSQDHLIVQEYIEKPFLME--GYKFDLRIYILVTSPLKIFLYHDGLVRMGTEKYNESNLTQLYMHLTNYSVNKHNEHFERDETEGSKRSIKWFTEFLQANQHDV--AKFWSDISELVVKTLIVAEPHVLHAYRESVCFEVLGFDILLDRKLKPWLLEINRAPSFGQKIDYDVKRGVLLNALKLLNIRTSDKRRNLAKQK..... 243
6 -77.500sp|A6NNM8|TTL13_HUMAN Tubulin polyglutamylase TTLL13 OS=Homo sapiens GN=TTLL13 PE=1 SV=2  ali   24  1.......................................................................CRKDLLARNLNRMYKL------YPSEYNIFPRTWCLPADYGDFQSYG---------------------RQRKARTYICKPDSGCQGRGIFITRNPREI-----KPGEHMICQQYISKPLLID--GFKFDMRVYVLITSPLRIFTYEEGLARFATTPYSHNNLDNVCMHLTNYAINKHNENFVRDGAVGSKRKLSTLNIWLQEHSYNP--GELWGDIEDIIIKTIISAHSVLRHNYRTCACFEILGFDILLDHKLKPWLLEVNHSPSFTSCLDQEVKDALLCDAMTLVNLRGCDKRKVMEEDKR.... 284
7 -76.600sp|Q6ZVT0|TTL10_HUMAN Inactive polyglycylase TTLL10 OS=Homo sapiens GN=TTLL10 PE=1 SV=2  ali   26  2..........................................................................................................................................TLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKGPQARVVQRYIQNPLLVD--GRKFDVRSYLLIACPYMIF-FGHGYARLTLSLYDP-HSSDLGGHLTNQFMQKKSPLY-MLLKEHTVWSMEHLNRYISDTFWKAVFTTLKKRMQQIMAHCFLAAKPKLDCKL---GYFDLIGCDFLIDDNFKVWLLEMNSNPALNCEVLKEVIPGVVIETLDLVLETFRKSLRGQKSQRRFVLL 265
8 -75.200sp|Q8N841|TTLL6_HUMAN Tubulin polyglutamylase TTLL6 OS=Homo sapiens GN=TTLL6 PE=2 SV=2  ali   25  1........................................................................................................WCLPADWGDLQTYS---------------------RSRKNKTYICKPDSGCQGKGIFITRTVKEI-----KPGEDMICQLYISKPFIID--GFKFDLRIYVLVTSPLRIFVYNEGLARFATTSYCTDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYNV--EQIWRDIEDVIIKTLISAHPIIRHNYHTCACFEILGFDILLDHKLKPWLLEVNHSPSFSSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQ.... 255
9 -74.700sp|Q14166|TTL12_HUMAN Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens GN=TTLL12 PE=1 SV=2  ali   17  12...............QQVASSLTHPRFTLT-QSEADADILFNFSHFKDYRKL-SQERPGVLLNQFPCENLLTVKDCLASIARRAG--------GPEGPPWLPRTFNLRTE-----------------LPQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHSIIRHRE--STPKVVSKYIESPVLFLRGKVKFDIRYIVLLRSPLRLFVYDVFWLRFSNRAFALNDLDDYEKHFTVMNYDPDVVLK----QVHCEEFIPEFEKQYPEF--------PWTDVQAEIFRAFTELFQVACAKPDYPSSRAMYAVDLMLKWDNGPDGRRVM............................................. 299
10 -73.800sp|Q6EMB2|TTLL5_HUMAN Tubulin polyglutamylase TTLL5 OS=Homo sapiens GN=TTLL5 PE=1 SV=3  ali   23  1..................................................................................................HILPQTFLLPAEYAEFCNSY----------------------SKDRGPWIVKPVASSRGRGVYLINNPNQI-----SLEENILVSRYINNPLLID--DFKFDVRLYVLVTSPLVIYLYEEGLARFATVRYDQGNIRNQFMHLTNYSVNKKSGDYVSCDDPGNKWSMSAMLRYLKQEGRDT--TALMAHVEDLIIKTIISAELAIATACKRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLAAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRP..... 260
11 -73.700sp|Q9BWV7|TTLL2_HUMAN Probable tubulin polyglutamylase TTLL2 OS=Homo sapiens GN=TTLL2 PE=5 SV=3  ali follow..  23  84..LKPLVFRVDETTPAVVQSVLLERGWNKFDKQEEDWNLYWRTSSFRMTEH--NSVKPWQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGT-----SLYQFIPLTFVMPNDYTKFVAEYFQ---------------ERQMLGTKHSYWICKPAELSRGRGILIFSDFKDF-----IFDDMYIVQKYISNPLLIG--RYKCDLRIYVCVTGPLTIYVYQEGLVRFATEKFDLSNLQNNYAHLTNSSINKSGASYEKIKEVGCKWTLSRFFSYLRSWDVDD--LLLWKKIHRMVILTILAIAPSVPF---AANCFELFGFDILIDDNLKPWLLEVNYSPALTCSTDVLVKRKLVHDIIDLIYLNGLRNEGREASNAT.... 431
12 -73.200sp|Q14679|TTLL4_HUMAN Tubulin polyglutamylase TTLL4 OS=Homo sapiens GN=TTLL4 PE=1 SV=2  ali   23  4..RKLLRWKMSTVTPNIVKQTIGRSHFKIS-KRNDDWLGCWGHHMKS---PSFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFG-----KKEFSFFPQSFILPQDAKLLRKAW---------------------ESSSRQKWIVKPPASARGIGIQVIHKWSQL-----PKRRPLLVQRYLHKPYLIS--GSKFDLRIYVYVTSPLRIYLFSDGLVRFASCKYSMKSLGNKFMHLTNYSVNKKNAEYQANADEGHKWALKALWNYLSQKGVNS--DAIWEKIKDVVVKTIISSEPYVTSLLKMYSCHELFGFDIMLDENL..................................................... 300
13 -72.300sp|Q8NHH1|TTL11_HUMAN Tubulin polyglutamylase TTLL11 OS=Homo sapiens GN=TTLL11 PE=2 SV=1  ali follow..  18  218..PVTVDSSKARTSLDALKISIRQLKWKEFPGRRLPCDIYWHGVS------FHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNL------FPEEYNFYPRSWILPDEFQLFVAQVQMV---------------KDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLID--KLKFDIRLYVLLKSPLEIYIAKDGLSRFCTEPYTPKNLHRIFMHLTNYSLNIHSGNFIHSDSAGSKRTFSSILCRLSSKGVDI--KKVWSDIISVVIKTVIALTPELKVFYQSDPGPTCFQVTIASSQPAFPALTGLKRALWLRV...................................... 537
14 -69.600sp|Q6ZT98|TTLL7_HUMAN Tubulin polyglutamylase TTLL7 OS=Homo sapiens GN=TTLL7 PE=2 SV=2  ali   22  38..KGTITANVAGTKFEIVRLVIDEMGFMKTPDEDETSNLIWCDSAVQQEKI--SELQNYQRINHFPGMGEICRKDFLARNMTKMIKS------RPLDYTFVPRTWIFPAE-----------------YTQFQNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKL-----PSQDHLIVQEYIEKPFLME--GYKFDLRIYILVTSPLKIFLYHDGLVRMGTEKYNESNLTQLYMHLTNYSVNKHNEHFERDETEGSKRSIKWFTEFLQANQHDV--AKFWSDISELVV...................................................................................... 300
15 -69.100sp|Q9Y4R7|TTLL3_HUMAN Tubulin monoglycylase TTLL3 OS=Homo sapiens GN=TTLL3 PE=1 SV=2  ali   26  1.............................................................................................................................................................EMLKLVNGNPVV-----MKDGKWVVQKYIERPLLIF--GTKFDLRQWFLVTDPLTVWFYRDSYIRFSTQPFSLKNL-DNSVHLCNNSIQKHLENSCHRHPPDNMWSSQRFQAHLQEMGAPNASTIIVPGMKDAVIHALQTSQDTVQCRK---ASFELYGADFVFGEDFQPWLIEINASPTMSTAVTARLCAGVQADTLRVVI---DRMLDRNCDTGAFELI 215
16 -67.200sp|Q8N841|TTLL6_HUMAN Tubulin polyglutamylase TTLL6 OS=Homo sapiens GN=TTLL6 PE=2 SV=2  ali   23  58..KKRLVINLSSCRYESVRRAAQQYGFREG-GEDDDWTLYWTDYSVSLE--RVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKM------FPKDFRFFPRTWCLPADWGDLQTYS---------------------RSRKNKTYICKPDSGCQGKGIFITRTVKEI-----KPGEDMICQLYISKPFIID--GFKFDLRIYVLVTSPLRIFVYNEGLARFATTSYCTDNLDDICMHLTNYSINKHSSNFSRDAHSGSKRKLSTFSAYLEDHSYN..................................................................................................... 300
17 -66.500sp|Q9Y4R7|TTLL3_HUMAN Tubulin monoglycylase TTLL3 OS=Homo sapiens GN=TTLL3 PE=1 SV=2  ali   18  4VLKLVVKSEWKSYPIQAVEEEASGDKQPKKQEKNP--FVDEALCACEEYLSNLAHMDIDKDLEAPLYLTPEGWSLFLQRYYQVVHEGAE----LRHLDTQVQRCEDILQQLQAV--------------------VPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGKDGKWVVQKYIERPLLIF--GTKFDLRQWFLVTDPLTVWFYRDSYIRFSTQPFSLKNLDN-SVHLCNNSIQKHLENSCHRHPPDNMWSSQRFQAHLQEMGAPNASTIIVPGMKDAVIHALQTSQDTVQCRK---ASF.................................................................. 300
18 -65.100sp|Q6EMB2|TTLL5_HUMAN Tubulin polyglutamylase TTLL5 OS=Homo sapiens GN=TTLL5 PE=1 SV=3  ali   22  62..RYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPF--LLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGF-----KAFHILPQTFLLPAEYAEFCNSY----------------------SKDRGPWIVKPVASSRGRGVYLINNPNQI-----SLEENILVSRYINNPLLID--DFKFDVRLYVLVTSPLVIYLYEEGLARFATVRYDAKNIRNQFMHLTNYSVNKKSGDYVSCDDPGNKWSMSAM............................................................................................................... 299
19 -64.500sp|Q6ZVT0|TTL10_HUMAN Inactive polyglycylase TTLL10 OS=Homo sapiens GN=TTLL10 PE=1 SV=2  ali   19  8.....FFYIGGSNGATIISSYCKSKGWQRIDSRRDDYTLKWCEVKSRDSYG--SFREGEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKAQRVLRMEEFFPETYRLDLKHEREAFFT---------------------LFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTPQARVVQRYIQNPLLVD--GRKFDVRSYLLIACPYMIF-FGHGYARLTLSLYD-PHSSDLGGHLTNQFMQKKSPLY-MLLKEHTVWSMEHLNRYISDT........................................................................................................ 300
20 -61.700sp|Q14679|TTLL4_HUMAN Tubulin polyglutamylase TTLL4 OS=Homo sapiens GN=TTLL4 PE=1 SV=2  ali   28  1........................................................................................................................................................................................YLHKPYLIS--GSKFDLRIYVYVTSPLRIYLFSDGLVRFASCKYSPSSLGNKFMHLTNYSVNKKNAEYQANADEGHKWALKALWNYLSQKGVNS--DAIWEKIKDVVVKTIISSEPYVTSLLKPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSPLDISIKGQMIRDLLNLA.................... 185
21 -59.500sp|Q14166|TTL12_HUMAN Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens GN=TTLL12 PE=1 SV=2  ali   20  1.......................................................................................................................................................................................KYIESPVLFLRGKVKFDIRYIVLLRSPLRLFVYDVFWLRFSNRAFALNDLDDYEKHFTVMNYDPDVVLK----QVHCEEFIPEFEKQYPEFPWTDVQAEIFRAFTELFQVACAKPPPLGLCDYP--SSRAMYAVDLMLKWDMQPQILEVNFNPDCER--ACRYHPTFFNDVFSTLFLDQPGGCHVTC........ 192
22 -59.000sp|A6NNM8|TTL13_HUMAN Tubulin polyglutamylase TTLL13 OS=Homo sapiens GN=TTLL13 PE=1 SV=2  ali   24  85..RRSLAINLTNCKYESVRRAAQMCGLKEV-GEDEEWTLYWTDCAVSLE--RVMDMKRFQKINHFPGMTEICRKDLLARNLNRMYKL------YPSEYNIFPRTWCLPADYGDFQSYG---------------------RQRKARTYICKPDSGCQGRGIFITRNPREI-----KPGEHMICQQYISKPLLID--GFKFDMRVYVLITSPLRIFTYEEGLARFATTPYSHNNLDNVCMHLTNYAINKHNE................................................................................................................................ 300
23 -59.000sp|A6PVC2|TTLL8_HUMAN Protein monoglycylase TTLL8 OS=Homo sapiens GN=TTLL8 PE=1 SV=3  ali   21  96.....................................................EHEDIDTSADAVEDLTEAEWEDLTQQYYSLVHG----DAFISNSRNYFSQCQALLNRITSVN--------------------PQTDIDGLRNIWIIKPAAKSRGRDIVCMDRVEEILELAAARDNKWVVQKYIETPLLIC--DTKFDIRQWFLVTDPLTIWFYKESYLRFSTQRFSL-DKLDSAIHLCNNAVQKYLKNDVGRSPAHNMWTSTRFQEYLQRQG....................................................................................................... 300
24 -48.500sp|A4D0V7|CG058_HUMAN(removed signalp:1-34) Uncharacterized protein C7orf58 OS=Homo sapiens GN=C7orf58 PE=2 SV=1  ali   13  1.................................................................PEQQPLCRKEGLCQIVRRF----------PELQLPVSPSVCLDQGMQ-------------------------KPSTSSHLLKTVKPRVWKPGDWSR-------------EQLNETTVLAPHETIFRAE--DLSVILKAYVLVTSPLRAFIHSTGTVWNPPKKKFTVKLQTFFETFLRASSPQQ----------------------------------AFDIMKEAIGKLLLAAEVFSETSTLGRFCFQLLTFDIGYGSFMYPVVLQVHEHLNFQDY-DQNTEEFLLNDTFNFLFPNESSLSIFSEIFQR.... 242
25 -40.000sp|Q14679|TTLL4_HUMAN Tubulin polyglutamylase TTLL4 OS=Homo sapiens GN=TTLL4 PE=1 SV=2  ali   17  154..RKLLRWKMSTVTPNIVKQTIGRSHFKISKRND-DWLGCWGHHMKS---PSFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFG-----KKEFSFFPQSFILPQDAKLLRKAW---------------------ESSSRQKWIVKPPASARGIGIQVIHKWSQL-----PKRRPLLVQR.................................................................................................................................................................................................. 300
26 -39.800sp|Q6ZVT0|TTL10_HUMAN Inactive polyglycylase TTLL10 OS=Homo sapiens GN=TTLL10 PE=1 SV=2  ali   22  1.............................................................................................................................................................................................................................................................................FWKARGLAKVFTTLKKRMQQIMAHCFLAAKPKLDCKL---GYFDLIGCDFLIDDNFKVWLLEMNSNPALNCEVLKEVIPGVVIETLDLVLETFRKSLRPLLSQRRFVLL 115
27 -38.100sp|A6NNM8|TTL13_HUMAN Tubulin polyglutamylase TTLL13 OS=Homo sapiens GN=TTLL13 PE=1 SV=2  ali   19  1..........................................................................................................................................................................................................................................................NFVRDGAVGSKRKLSTLNIWLQEHSYNP--GELWGDIEDIIIKTIISAHSVLRHNYRTCACFEILGFDILLDHKLKPWLLEVNHSPSFTSCLDQEVKDALLCDAMTLVNLRGCDKRKVMEEDKR.... 134
28 -37.300sp|A6PVC2|TTLL8_HUMAN Protein monoglycylase TTLL8 OS=Homo sapiens GN=TTLL8 PE=1 SV=3  ali   23  2...................................................................................................................................................................................................................................................................................GAVWGSVIYPSMKKAIAHAMKVAQDHVEPRK---NSFELYGADFVLGRDFRPWLIEINSSPTMSTPVTAQLCAQVQEDTIKVAV-------DRSCDIGNFELL 96
29 -35.500sp|A4D0V7|CG058_HUMAN(removed signalp:1-34) Uncharacterized protein C7orf58 OS=Homo sapiens GN=C7orf58 PE=2 SV=1  ali   13  80LHQHILTQHGYTVVIAEERLNAGLGPGLLEQGDLGSWDLLIAEGTPCISKEVMCQLGLHQKANRLPEIQQLCRKEGLCQIVRRFPEL---------------QLPVSPSVCLDQGMQLK-------------------PSTSSHLLKTVKPRVWKPGDWSREQLN-------------ETTVLAPHETIFRAE--DLSVILKAYVLVTSPLRAFIHSTGTVWNPPKKKRFTKLQTFFETFLRASSPQQAFDIMKE........................................................................................................................... 295
30 -32.300sp|Q8N841|TTLL6_HUMAN Tubulin polyglutamylase TTLL6 OS=Homo sapiens GN=TTLL6 PE=2 SV=2  ali   24  1.......................................................................................................................................................................................................................................................................................VEQIWRDIEDVIIKTLISAHPIIRHNYHTCACFEILGFDILLDHKLKPWLLEVNHSPSFSSRLDKEVKDGLLYDTLVLINLESCDKKKVLEEERQ.... 105
31 -32.000sp|Q14166|TTL12_HUMAN Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens GN=TTLL12 PE=1 SV=2  ali   14  162...............QQVASSLTHPRFTLT-QSEADADILFNFSHFK-DYRKLSQERPGVLLNQFPCENLLTVKDCLASIARRAGG--------PEGPPWLPRTFNLRTE-----------------LPQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHS------------IIRHRESTPKVV.......................................................................................................................................................................................... 299
32 -32.000sp|Q6EMB2|TTLL5_HUMAN Tubulin polyglutamylase TTLL5 OS=Homo sapiens GN=TTLL5 PE=1 SV=3  ali   24  1............................................................................................................................................................................................................................................................................RYLKQEGRDT--TALMAHVEDLIIKTIISAELAIATACKTFSCFELYGFDVLIDSTLKPWLLEVNLSPSLAAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPI.... 111
33 -30.600sp|Q9Y4R7|TTLL3_HUMAN Tubulin monoglycylase TTLL3 OS=Homo sapiens GN=TTLL3 PE=1 SV=2  ali   29  1........................................................................................................................................................................................................................................................................................................................ELYGADFVFGEDFQPWLIEINASPTMSTAVTARLCAGVQADTLRVVI---DRMLDRNCDTGAFELI 65
34 -28.500sp|Q6ZT98|TTLL7_HUMAN Tubulin polyglutamylase TTLL7 OS=Homo sapiens GN=TTLL7 PE=2 SV=2  ali   25  1....................................................................................................................................................................................................................................................................................................KTLIVAEPHVLHAYRMCVCFEVLGFDILLDRKLKPWLLEINRAPSFGQKIDYDVKRGVLLNALKLLIRTSDKRRNLAKQKAEAQ.. 97
35 -24.000sp|A6PVC2|TTLL8_HUMAN Protein monoglycylase TTLL8 OS=Homo sapiens GN=TTLL8 PE=1 SV=3  ali   30................VVRAALRRKGWVEKKFKNEMPYLLWTIKRDIIDY---HSLTYDQMLNHYAKTASFTTKIGLCVNMRSLPWYVPA-----NPDSFFPRCYSLCTE---------------SEQQEFLEDFRRTMASSILK-WVVSHQSCSRSSRSKPRDQREEA-----GSSDLSSRQDAENAEAKL--RGLPGQLVDIACKVAYLGQLEHEDIDTSADAVEDLTEAEWEDLTQ-QYYSLVHGDAFISNSRNSQCQALLNRI............................................................................................................... 299
36 -21.600sp|A4D0V7|CG058_HUMAN(removed signalp:1-34) Uncharacterized protein C7orf58 OS=Homo sapiens GN=C7orf58 PE=2 SV=1  ali   12  1.................................................................................................................................................................................................................................................................................................LLAAEVFSETSTLKTFHRCRFCFQLLTFDIGYGSFMYPVVLQVHEHLNFQDY-DQNTEEFLLNDTFNFLFPNESSLSIFSEIFQR.... 92
37 -18.300sp|P17600|SYN1_HUMAN Synapsin-1 OS=Homo sapiens GN=SYN1 PE=1 SV=3  ali   117...................................................................................................................................................VVKMGHAHSGMGKVKVDNFQDIASVVALTKTYATAEPFIDA---------KYDVRVQKI--------------------------------NYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLW----------------------------VDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGR.... 280
38 -17.400sp|Q9Y4R7|TTLL3_HUMAN Tubulin monoglycylase TTLL3 OS=Homo sapiens GN=TTLL3 PE=1 SV=2  ali   15  29................VIRCLLRRRGWEKKMVHRSGPTLLPPQKDLDSSAMGDSDFDFDDLLKFDDLDGTHALMVGLCLNLRNLPDEVDANSFFPRCYCFLQRYYQVVHEGAELRHLDTQVQRCEDILQQLQAVVPQIDMEGDRNIWIVKPGAKSRGRGIMCMDHLE................................................................................................................................................................................................................... 300
39 -17.100sp|Q14679|TTLL4_HUMAN Tubulin polyglutamylase TTLL4 OS=Homo sapiens GN=TTLL4 PE=1 SV=2  ali   23  1.....................................................................................................................................................................................................................................................................................................................................KPWVLEVNISPSLHSPLDISIKGQMIRDLLNLAFVLPNAEDIISSPS...... 50
40 -15.700sp|Q8IXN7|RIMKA_HUMAN Ribosomal protein S6 modification-like protein A OS=Homo sapiens GN=RIMKLA PE=2 SV=2  ali follow..  15  152...................................................................................................................................................VVKSTRGHRGKAVFLARDKHHLSDICHRHDVPYLFQKYVKE-------SHGKDIRVVVVGGQVI-------SMLRCSTDGRMQSNC---------------------------------------SLGGVGVKCPLTEQGKQLAIQVSNILG------------MDFCGIDLLIMDDGSFVVCEANANVGFLA-FDQACNLDVGGIIADYTMSLLPNRQTGKMAV...... 313
41 -15.400sp|Q9ULI2|RIMKB_HUMAN Ribosomal protein S6 modification-like protein B OS=Homo sapiens GN=RIMKLB PE=2 SV=2  ali follow..  15  156...................................................................................................................................................VVKNTRGHRGKAVFLARDKHHLADLSHRHEAPYLFQKYVKE-------SHGRDVRVIVVGGRVV-------TMLRCSTDGRMQSNC---------------------------------------SLGGVGMMCSLSEQGKQLAIQVSNILG------------MDVCGIDLLMKDDGSFCVCEANANVGFIA-FDKACNLDVAGIIADYAASLLPSGRLTRR........ 315
42 -13.700sp|Q13572|ITPK1_HUMAN Inositol-tetrakisphosphate 1-kinase OS=Homo sapiens GN=ITPK1 PE=1 SV=2  ali follow..  11  94.............................................................LDPLPAIRTLLDRSKSYELIRKIE---------------MEDDRICSPPFMELTSLCG------------DDTMRLLEKNGLTFPFICKTAHGTNSHEMAIVFNQEGLNAI----QPPCVVQNFINHN---------VLYKVFVVGESYTVV-------QRPSLKNFSAGTSDRESIFFNSHNVSKPESSSVLTE---------------LDKIEGVFERPSDEVIRELSRALRQALG------------VSLFGIDIIINNQ-QHAVIDINAFPGYEG------VSEFFTDLLNHIATVLQGQSTAMAATG..... 331
43 -12.400sp|Q6PFW1|VIP1_HUMAN Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 OS=Homo sapiens GN=PPIP5K1 PE=1 SV=1  ali   46...................................................................................................................................................VEKPVSAEDHNVYIYYPSSAG-PESSVRKTGSYIYEEFMPTD----------DVKVYTV---------------------------GPDYAH----AEARKSPALDGKVERD------------SEGKEIRYPVMLTAMEKLVARKVCVAFK-------------TVCGFDLLRANG-HSFVCDVNGFSFVKN--SMKYYDDCAKILGNTIMRELAPQFQIP......... 218
44 -11.600sp|Q6ZVT0|TTL10_HUMAN Inactive polyglycylase TTLL10 OS=Homo sapiens GN=TTLL10 PE=1 SV=2  ali   14  167..............ATIISSYCKSKGWQRIDSRRDDYTLKWCEVKSRDSYGSFRE--GEQLLYQLPNNKLLTTKIGLLSTLRGRARAMSKASKVPRMEEFFPETYRL---------------DLKHEREAF....................................................................................................................................................................................................................................................... 300
45 -9.460sp|Q96RQ3|MCCA_HUMAN Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens GN=MCCC1 PE=1 SV=3  ali   11  53...................................................................................................................................................MIKAVRGGGGKGMRIVRSEQEFQEQLESADDAMLIEKFVDTP-------RHVEVQVF--------------------------GDHHGNAVYLRDCSVQRRH------------------QKIIEEAPAPGIKSEVRKKLGEAAVRAAKAVN------------YVGAGVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGDLVEWQLRIA.................... 213
46 -9.240sp|P05165|PCCA_HUMAN Propionyl-CoA carboxylase alpha chain, mitochondrial OS=Homo sapiens GN=PCCA PE=1 SV=4  ali   16  67...................................................................................................................................................MIKASAGGGGKGMRIAWDDEETRDGFRLSDDRLLIEKFIDNP-------RHIEIQVL--------------------------GDKHGNALWLRECSIQRRN------------------QKVVEEAPSIFLDAETRRAMGEQAVALARAVK------------YSSAGVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGDLVQEMIRVA.................... 227
47 -9.180sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapiens GN=ACACA PE=1 SV=2  ali   10  9...................................................................................................................................................MIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVFVMRLAKQS-------RHLEVQI--------------------------LADQYGNAISLRDCSVQRRH------------------QKIIEEAPATIATPAVFEHMEQCAVKLAKMVG------------YVSAGVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADNLPAAQLQIA.................... 165
48 -9.030sp|P11498|PYC_HUMAN Pyruvate carboxylase, mitochondrial OS=Homo sapiens GN=PC PE=1 SV=2  ali   18  42...................................................................................................................................................IFKAAYGGGGRGMRVVHSYEELEENYTRANGALFVEKFIEKP-------RHIEVQIL--------------------------GDQYGNILHLRDCSIQRRH------------------QKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVG------------YENAGVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDDLVHAQIHVA.................... 202

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.