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Query: 2e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase, from PDB1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSGSYYNGISTNLLast
1 -8.440sp|Q9BRP7|FDXA1_HUMAN Ferredoxin-fold anticodon-binding domain-containing protein 1 OS=Homo sapiens GN=FDXACB1 PE=2 SV=3 (Range: 341-413)  ali follow..  16  1.........................................................................................................................GQAKICLRPSLLVHVQDVIEVPDFL---SGSLHILGPVFQKCHILPFTMPAFHET-ILGVNQNLKDGCLQSLLD.......................................................................................... 73
2 -7.910sp|Q4G163|FBX43_HUMAN F-box only protein 43 OS=Homo sapiens GN=FBXO43 PE=1 SV=3 (Range: 58-169)  ali follow..  13  14..................................................................................SSFQDSGYNELKSCSFDNIDKEYLGKKEKGPTLLYEHPETSGLGLTHPLESPTQKKKCILPRKEKDKTPELCETPKISGKKCLPRRRL................................................................................................................... 101
3 -6.020sp|Q9HCD6|TANC2_HUMAN Protein TANC2 OS=Homo sapiens GN=TANC2 PE=1 SV=3 (Range: 451-619)  ali follow..  14  63..........................................................................................ASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTV---RTSLQEITKLLPFHRIFLDLEENEAIDQDLQAYILHRIH...................................................................................... 169
4 -6.020sp|P53804|TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 OS=Homo sapiens GN=TTC3 PE=1 SV=2 (Range: 1073-1169)  ali follow..  12  6............................................EEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFETRQILEKAGG................................................................................................................................................................................ 79
5 -5.830sp|Q9C0D5|TANC1_HUMAN Protein TANC1 OS=Homo sapiens GN=TANC1 PE=1 SV=3 (Range: 502-668)  ali follow..  14  62..........................................................................................AAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTV---RANFQEIISALPFVKLSLDFPDNKDIHSDLHAYVQHRV....................................................................................... 167
6 -4.600sp|Q9ULT6|ZNRF3_HUMAN Zinc/RING finger protein 3 OS=Homo sapiens GN=ZNRF3 PE=2 SV=3 (Range: 773-843)  ali follow..  12  4...................................................................................................................................................GLPCCFYEEKQVARGGGGGSGCYTEDYSVSVQYTLTEEPPPGCYPGARDLSQRIPI.................................................................................. 59
7 -4.480sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 (Range: 431-550)  ali follow..  8...................................................................................................................................LGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKF---MVFQDLLTNKDDYLRASRALLREIIKQTKHE................................................................................. 79
8 -4.480sp|Q8NCE2|MTMRE_HUMAN Myotubularin-related protein 14 OS=Homo sapiens GN=MTMR14 PE=1 SV=2 (Range: 546-650)  ali follow..  52................................................................................................................................................................RETRLQEVRLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLR................................................................................. 98
9 -4.370sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 (Range: 1600-1785)  ali follow..  12  16.............................................................LDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLA--RILFRMYVDENRRDSWEEIQQRLLTVCSEALAESHREAWTSLLLLLLTKTLKINDEKKAHASMYYPYLCEIMQFDLI-PELRAVLRKFFLRIG................................................................................... 164
10 -4.330tr|Q5T5A0|Q5T5A0_HUMAN Chromosome 9 open reading frame 24 OS=Homo sapiens GN=C9orf24 PE=2 SV=1 (Range: 1-164)  ali follow..  12  1............................METAVRGMPLECPPRPERLNAYEREVMVNMLNSLSRNQQLPRITPRCGCVDPLPGRLPFHGYESACS-CLRGMDYYASGAPCTDRRLRPWCREQPTVRCVPPYEHRPGMQCAVSHFKKSGGPQR-YVIHPEFVSETYPD...................................................................................................................... 160

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rodrigues AP, Grant BJ, Godzik A, Friedberg I. The 2006 automated function prediction meeting. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S1-4.