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Query: 4tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase, from PDB1018

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLSFIQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNLLast
1 -8.720sp|Q9BRP7|FDXA1_HUMAN Ferredoxin-fold anticodon-binding domain-containing protein 1 OS=Homo sapiens GN=FDXACB1 PE=2 SV=3 (Range: 341-413)  ali follow..  16  2..........................................................................................................................QAKICLRPSLLVHVQDVIEVPDFL---SGSLHILGPVFQKCHILPFTMPAFHET-ILGVNQNLKDGCLQSLLD.......................................................................................... 73
2 -7.660sp|Q4G163|FBX43_HUMAN F-box only protein 43 OS=Homo sapiens GN=FBXO43 PE=1 SV=3 (Range: 58-169)  ali follow..  13  14..................................................................................SSFQDSGYNELKSCSFDNIDKEYLGKKEKGPTLLYEHPETSGLGLTHPLESPTQKKKCILPRKEKDKTPELCETPKISGKKCLPRRRL................................................................................................................... 101
3 -5.890sp|Q9HCD6|TANC2_HUMAN Protein TANC2 OS=Homo sapiens GN=TANC2 PE=1 SV=3 (Range: 451-619)  ali follow..  14  63..........................................................................................ASFRRGVLEPLENLHKERKIPDEDFIILIDGLNEAEFHKPDYGDTIVSFLSKMIGKFPSWLKLIVTV---RTSLQEITKLLPFHRIFLDLEENEAIDQDLQAYILHRIH...................................................................................... 169
4 -5.760sp|Q9C0D5|TANC1_HUMAN Protein TANC1 OS=Homo sapiens GN=TANC1 PE=1 SV=3 (Range: 502-668)  ali follow..  15  62..........................................................................................AAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTV---RANFQEIISALPFVKLSLDFPDNKDIHSDLHAYVQHRV....................................................................................... 167
5 -5.460sp|P53804|TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 OS=Homo sapiens GN=TTC3 PE=1 SV=2 (Range: 1073-1169)  ali follow..  12  6............................................EEFEALYDQHSNEYVVRNKKLWDMNPKQKCSTLYDYFSQFLEEHGPLDMSNKMFETRQILEKAGG................................................................................................................................................................................ 79
6 -4.610sp|Q8N201|INT1_HUMAN Integrator complex subunit 1 OS=Homo sapiens GN=INTS1 PE=1 SV=2 (Range: 431-550)  ali follow..  7..................................................................................................................................NLGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKF---MVFQDLLTNKDDYLRASRALLREIIKQTKHE................................................................................. 79
7 -4.300sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 OS=Homo sapiens GN=ARFGEF2 PE=1 SV=3 (Range: 1600-1785)  ali follow..  12  16.............................................................LDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSSLA--RILFRMYVDENRRDSWEEIQQRLLTVCSEALAESHREAWTSLLLLLLTKTLKINDEKKAHASMYYPYLCEIMQFDLI-PELRAVLRKFFLRIG................................................................................... 164
8 -4.190sp|Q5SR76|CJ093_HUMAN TPR repeat-containing protein C10orf93 OS=Homo sapiens GN=C10orf93 PE=2 SV=2 (Range: 1420-1530)  ali follow..  12  27.........................................................................................................................VNPSSIQKPTYSLYFLDHLVKALQKMC--VPVLQLGVLISDSVVGSKGLSDLYHLRWVQLLFRSVISPKQNKNKQHVKVLIL.................................................................................. 111
9 -4.170tr|B7Z5F2|B7Z5F2_HUMAN Uncharacterized protein OS=Homo sapiens PE=2 SV=1 (Range: 1-186)  ali follow..  12.............................TVTKTAWYRYQNRDIDQWNRTEPSEITKPEKNKQWGKDSLFNKWCWENWLAICRKLKLDPFLTPYTKINSRWIKYLNVRPKTIKTVEENLGITIQDIGMGKDFMSKTPKAMATKAKI-----DLIKLKSFCTAKETTIRVNRQPTKWEKIFATYSSD----KGLISRIYNE..................................................................................... 186
10 -4.100sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens GN=ARFGEF1 PE=1 SV=2 (Range: 1674-1849)  ali follow..  14  10.............................................................LDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLA--RILFRMYMDESRVSAWEEVQQRLLNVCSEALSESHREAWTNLLLLFLTKVLKISDNRKAHASFYYPLLCEIMQFDLI-PELRAVLRRFFLRIG................................................................................... 158

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.