current user: public

Please be advised that we have recently moved our server to a new location. We tried our best to fully test all functions on the website, but if something does not work for you please let us know.

Query: 3a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470
# Score Template Links and tools%idFirst MASGQDKTHIDYAYELDITVKPDSRVPVFNREFATFTGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMYLFDIEGHEFAVKPMNCPYHILLFLNEVAKHRSKLPLPFKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKLGVSSETFKVRLSMSDKSLIGKEFMGSKEEWEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFIMMVEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREEFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTGGEVDREIEDLASSIAKGLLDKGFRVAVKGSSKTGLSSDVRHIESTAKPAVNVFIGAKEVREKVLDVRVFDLESMKRRRLAIAYGDAADAVENLAAVAEELESPVRSLSGQAPRIPADFSFMLLast
1 -156.0003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model  100  1MASGQDKTHIDYAYELDITVKPDSRVPVFNREFATFTGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMYLFDIEGHEFAVKPMNCPYHILLFLNEVAKHRSKLPLPFKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKLGVSSETFKVRLSMSDKSLIGKEFMGSKEEWEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFIMMVEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREEFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTGGEVDREIEDLASSIAKGLLDKGFRVAVKGSSKTGLSSDVRHIESTAKPAVNVFIGAKEVREKVLDVRVFDLESMKRRRLAIAYGDAADAVENLAAVAEELESPVRSLSGQAPRIPADFSFML 471
2 -127.0004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  31  1...............MGSSSSGDHRKIGRDQELYFFLSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPR---SWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFG------FSFKLNLST-----RPEKFLGDIEVWDQAEKQLENSLNEFGEKWELN----SGDGAFYGPKIDIQ---IKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGP------TCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFI-LVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEE....................... 407
3 -125.0004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model follow..  31  2....................ARDHRKIGRDQELYFFLSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPR---SWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFG------FSFKLNLST-----RPEKFLGDIEVWDQAEKQLENSLNEFGEKWELN----SGDGAFYGPKIDIQ---IKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGP------TCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFI-LVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEE....................... 403
4 -119.0004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model follow..  29  2....................ARDHRKIGKQLDLYHMEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLK---SYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGF-----EKIVVKLST-----RPEKRIGSDEMWDRAEADLAVALEENNIPFEYQ----LGEGAFYGPKIEFT---LYDCLDRAWQCGTVQLDFSLPSRLSASYVGED-NERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITD------SQSEYVNELTQKLSNAGIRVKADLRNE-KIGFKIREHTLRRVPYM-LVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLE....................... 402
5 -116.0001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  28  220TAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPLDETESMVLRPMNCPHHMMIYANKPH---SYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFE-----DYSFRLSYR-DPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEA----IGEAAFYGPKLDVQ---VKTAMGKEETLSTAQLDFLLPERFDLTYIGQD-GEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVD-----LHYDYARQLQDELKSQGVRVSIDDRNE-KMGYKIREAQMQKIPYQ-IVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR.......................... 645
6 -115.0003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model follow..  26  15MASATKNAS-------SATPATMTSMVSQRQDLFMTLSPGSMFFLPNGAKIFNKLIEFMKLQQKKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVDEEKEEYGLKPMNCPGHCLIFGKKDR---SYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFIN-FSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLN----PGDGAFYGPKLDIM---VTDHLRKTHQVATIQLDFQLPERFDLKFKDQD-NSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCEADDMEPVPLNDWHFNVDLDIRNE-PVGYRIKSAILKNYSYL-IIVGDEEVQLQKYNIRERDNRSFEKLTMSQIWEKFIELEKNYK............................ 454
7 -110.0001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  28  221TAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLK---SYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFE-----KIVVKLST-----RPEKRIGSDEMWDRAEADLAVALEENNIPFEYQ----LGEGAFYGPKIEFT---LYDCLDRAWQCGTVQLDFSLPSRLSASYVGED-NERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITD------SQSEYVNELTQKLSNAGIRVKADLRNE-KIGFKIREHTLRRVPYM-LVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLE....................... 641
8 -76.4002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  12  18....SRFFLPILKENPKEAEIVSHRLMLR-AGMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIADHKRELLYGPTNEEMITEIFRAYIK---SYKSLPLNLYHIQWKFRDEQRPR-FGVMRGREFLMKDAYSFDVDEAGARKYNKMFVAYLRTFARMG----------LKAIPMRAETGPIGGDLSHEFIVLAETGESGVYIDRDVLNLPV----PDENVDYDGDLTPIISEVPEANRLNTRGIEVGQIFYFGTKYKANVTGPDG--TDAPIHGGSYGVGVSRLLGAIIEACHDDNWPEAVAPFRVTILNLKQGD---AATDAACDQLYRELSAKGVDVLYDDTDQ-RAGAKFATADLIGIPWQ-IHVGPRGLAEGKVELKRRSDGARENLALADVVARLT................................... 452
9 -72.0005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  16  1.............GAMGIAAKREENFSAWYIDVITKAESGCYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSLEREKDHIEGFAPEVAWVTRAEQPVAVRPTSETVMYPYYAKWIR---SHRDLPVRLNMWNNVIRWEFSHP-TPFIRTREFLWQEGHCAWKAEECAKEVLEILECYASVYEQLLAV---------------------------------------------VVRGRKTEKEKFAGGDYTTTVETF---IEAVGRGCQGATSHNLGQNFGKMFDIRFQDPEN--NEQTLIPWQNSWGLSTRVIGVMIMVHGDNMPPRVASTQVIIIPVDTTEEARQELLASCWRLESELCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLR-VELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHA.......................... 400
10 -68.9005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model follow..  12  1MASKENESLLGITADKITSFADWYSQVIVKSEMIEYYISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKLETEKDHVEGFSPEVAWVTKSAEPIAIRPTSETIMYPYFAKWIR---SHRDLPLKINQWTSIVRWEFKHPT-PFIRTREFLWQEGHTAHSTRKEALEMVDII-------------------------------------------LNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGF---IPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKG----NKEYAHQTSWGLTTRAIGVMIMTHGDNLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLR-FEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTL 427
11 -68.5004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  13  15MASGAGEGQGPKKQTREENLADWYSQVITKSEMIEYHISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWTELAEPIAIRPTSETVMYPAYAKWVQ---SHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAI---------------------------------------------VVKGRKTEKEKFAGGDYTTTIEAF---ISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKI--PGEKQFAYQNSWGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCALSEEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIR-LEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKIL 454
12 -68.3001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  15  7LTPQSQDFSEWYLEVIQKAELADYGPV-----------RGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSLRKEAEHVEGFSPELAVVEELEEPLAVRPTSETVIGYMWSKWIR---SWRDLPQLLNQWGNVVRWEMR--TRPFLRTSEFLWQEGHTAHTREEAEEEVRRMLSIYARLAREYAAI---------------------------------------------VIEGLKTEKEKFAGAVYTTTIEALM----KDGKALQAGTSHYLGENFARAFDIKFQDRDL----QVKYVHTTSWGLSWRFIGAIIDDRGLVLPPRLAPIQVVIVPIYKDESR-ERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFR-VELGPKDLEGGQAVLASRLGGK-ETLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAV 417
13 -65.6001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  13  20....KKDPNRYHGEKMTEFSEWFHNILEEEIIDQRYPVKGMHVWMPHGFMIRKNTLKILRRIL-DRDHEEVLFPLLVEDELAKEAIHVKGFEDEVYWVSKLQRKLALRPTSETVMYPMFALWVR---SHTDLPMRFYQVVNTFRYETKHTRPLIRVREITTFKEAHIHATASEAEEQVERAVEIYKEFFNSLGI-------------------------------------------------PYLITRRPPWDKFPGSEYTVAFDTLMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEY----VHQTCYGLSDRVIASVIDESGLCLPPDVAAHQVVIVPIIFKKAA-EEVMEACRELRSRLEAAGFRVHLDDRDI-RAGRKYYEWEMRGVPLR-VEIGPRDLEKGAAVISRRDTGEKVTADLQGIEETLRELMKDILENLRTRAWERMESEIREAETLEEASRIV 438
14 -65.0003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model follow..  12  1..MAMGGDVTFSLTKTRDTFADWFDAIMDAAELVDRPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVIPESFKKESDHIKGFEAECFWVQPLEERLALRPTSETAIYSMFSKWVR---SYKDLPLKIHQTCTIFRHETKNTK-PLIRVREIHWNEAHCCHATAEAVSQLSDYWKVIDTIFSDELCFKGQ---------------------------------------------KLRRVCWDRFPGADYSEVS---DVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKA-NESVHPYLTCAGISTRVLACALSIHGDSGGVLPPLIAPIHVVIIPIGCGKKNNQESDQQVLGKVNEISKLGLRVSIDDDFSKSMGDKLYYYELKGVPLR-IEVGQRDLANGQCIVVPRDKDQKRVIPITEVMKVSSHTTENHELVVKNVIKDELD................ 416
15 -64.7004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  11  13................IENFSDWYTQVIVKSELIEYYISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNLEKEKNHIEGFSPEVAWVSNLPEEIAIRPTSETIMYSVFPKWIR---SYRDLPLKLNQWNTVVRWEFKQP-TPFIRTREFLWQEGHTAHKNEE---EAVKLVFDILDLYRRW------YEEYLAVPIIKGIKSEGEK----------------------------------FGGANFTSTAEA---FISENGRAIQAATSHYLGTNFAKMFKIEFEDENE----VKQYVHQTSWGCTTRSIGIMIMTHGDDLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIR-IEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNAL 423
16 -63.9004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  13  22................EENLADWYSQVITKSEMIEYHISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKHVADFAPEVAWVTELAEPIAIRPTSETVMYPAYAKWVQ---SHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAI---------------------------------------------VVKGRKTEKEKFAGGDYTTTIEAF---ISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKI--PGEKQFAYQNSWGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCGITNALSEEDKEKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIR-LEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKIL 438
17 -61.6005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  14  2........AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHLEKEKDHVEGFSPEVAWVSPLPEKIAIRPTSETIMYPAYAKWIR---SHRDLPLKLNQWCSVVRWEFKQP-TPFLRTREFLWQEGHTAHATEEEAWELVLDI---------------------------------------LELYRRWYEECLAVPVIKGEKSEGE----KFAGGKKTTTVEAF---IPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKR----LVHQTSWGCTTRSLGVMIMTHGDDIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLR-LELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPAL 419
18 -59.3001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  13  1.............GSHMLEFSEWYSDILEKAEIYDVPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAKEAHIKGFEDEVYWVTQLDVKLALRPTSETPIYYMMKLWVK---VHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMTFKEAHTAHTKEEAENQVKEAISIYKKFFDTLGI-------------------------------------------------PYLISKRPEWDKFPGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAYQTCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGK--EDIVMEKAKEIYEKLKGKFRVHIDDRDI-RPGRKFNDWEIKGVPLR-IEVGPKDIENKKITLFRRDTMEKFQVDETQLMEVVEKTLNNIMENI......................... 386
19 -55.9005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  15  10................STNFADWYTQVIVRGELVEYYISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQALEKEKDHVEGFKPEVAWVTHYPEKVAIRPTSETIMYPAYAKWIR---SHRDLPLKLNQWNNVVRWEFKQP-TPFLRTREFLWQEGHTAHATEE---EAYTLVLEILELYRQW------YEDYLAVPVIKGEKSENEKFAGGKKT--------------------------------------TTIEGIIPDTGRGIQAATS---HLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDLPPRVVAVQAVIIPIIFKETGGMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLR-LEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPAL 420
20 -54.0001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  13  1....AASSLDELVALC--------KRRGFIFQSSEIYGQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRLVLHYSGHEATFADPMVPRGGRGLLAYLRPETAQGIFVNFKNVLDATS--RKLGFGIAQIGKAFRNEITPR-NFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEM---GLSRENLVPY-----QQPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDF----DLGSHTKDQEALG---ITARVLRNEHSTQRLAYRDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNR---PEITEYAKRLKARLLALGLGRVLYEDTG-NIGKAYRRHDEVGTPFA-VTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR............................... 441
21 -48.4003qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  10  134...ENYKKPEQIAAATGAPAKLSHHEVLLRLDGYDPVGHRGYFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVMAKTAQLSQFDEELYKVIDGEDEYLIATSEQPISAYHAGEWFES--PAEQLPVRYAGYSSCFRREAGSDAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQSLG------LPYRVVGIVSGELNNAAAKKYDLEAW------------------------FPFQQEY----------------KELVSCSNCTDYQSRNLEIRCGIKQQN-QQEKKYVHCLNSTLSATERTICCILENYQKEDGLVIPEVLRKYIPGEP------EFIPYIKELPKNTTSVKKAKGKNPKNTT-SVKKAKGKNGSR............................................................................ 479
22 -41.3001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  12  73.VLHYSGHEATFADPMVDNRRLDHLLKEQPEEVLKRLYRAMEVEEENLHALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRPRGGRGLLAYLRPETAQGIFVNFKNVLDATSR--KLGFGIAQIGKAFRNEIT-PRNFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEM---GLSRENLVPYQQP-----PESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDL----GSHTKDQEALG---ITARVLRNEHSTQRLAYRDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNR---PEITEYAKRLKARLLALGLGRVLYEDTG-NIGKAYRRHDEVGTPFAVTVKDGTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRERLR............................... 504
23 -35.7002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  14  4....SKMLIPTLREVPNDAEVLSHQILLRA-GYIRQVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNLYRLKDNDRDYILGPTH---EETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSR-SGLLRGREFIMKDGYSFADEASLDQSYRDYEKAYSRIFERCGL-GKDSKEFMAISEIGEDTICYSTESDYAANLEMADVKLKNFLGADFLDEATEEDARRVLGAGFG--EDLRFVQEGDPIGHIFKLGT-----RYSDAMGATVLDENG--REKSVIMGCYGIG-VSRLLSAIVEQNADEWPTGIAPFDLHVVQMNVKD---EYQTKLSQEVEAMMTEAGYEVLVDDRNE-RAGVKFADADLIGCP-IRITVGKKAVD-GVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEV.......................... 571
24 -35.5005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  15  6....SQYLLSTLKETPADAVVISHQLLLRA-GMIRRLASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLKDHEREFCVGPTHEEVITDLARNELN---SYKQLPINFYQIQTKFRDEIRPR-FGLMRGREFIMKDAYSFLSQDSLQQTYDGMYQAYSKIFSRLGL-GSGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEKTIKTLVVHGAEEGTLVALIVRGDHELNEIKAANQPLVASPVIKRGIEVGIFQLGTKYSEAMKLSVLSEQG--KPVNLIMGCYGIG-VSRVVAAAIEQNHDEWPSALAPFQIALVPLKYET---ESVKQATDKLYAELTAAGFEVLLDDRDKKSPGVKFADMELIGIP-HRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLSR.............................. 573
25 -31.9002cim_A mol:protein length:522 SERYL-TRNA SYNTHETASE  ali model follow..  13  174.QYGAKAEHWNLLWQREPMEHPFKEDPTQAM-LKRGSSRGQWIHGPQSARIFRTFEKIVLEELLEPGYREMIFPKLVTWEVWMKSGHAKGVYPEIYYVKIAEPIGGMCYAQCPPFWMYVAGET---LPNEEIPVKVFDRGTSHRYE-SGGIHGIERVDEFHRIEIVWIGTKEEVLKCAEELHDRYMHIFNDILD-----------IEWRKARVTPWFMAQEGLLGLAEENTVGTTDYEACLPY-------------------------RGPDGEWLEFQNVSI--KYPKGFNVKLQSGD--------ELWSGCSGGLERWAAVFLAQKGLDPANWPEEFRNRVGEMPKG.......................................................................................................................... 512
26 -24.5001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  18  7................................................................................................................................................................................................................................................................................................................................................GPVDCSVIVVNK------QTKDYAESVGRKVRDLGMVVDLIFNTEVSLSQALEDVSRGGSPFA-IVITQQHQIHRSCTVNIMFGTEHRNMPQADAMVLVARNYERYKNECREKEREEIARQASGP.......... 127
27 -23.6002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  13  56LALQPKDDIVDRAKMEDTLKRR----YDQAFAIYGGVS-GLYDFGPVGCALKNNIIQTWRQHFQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFYLRPETAQGIFLNFKRLLEF--NQGKLPFAAAQIGNSFRNEIS---SGLIRVREFTMAEIEHFVDPSEDHPKFQNVADLHLYLYTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENESCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAIC-ETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSF--GLGRIMYTVFEHT--SFPAVVAPFKCSVLPLSQNQ----EFMPFVKELSEALTRHGVSHKVDDSSG-SIGRRYARTDEIGVAFGVTIDFDTNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNI............................ 660
28 -23.2004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  12  43.....EEEVAKLLKLKAQLGPDE-----SKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLKDQGELLSLRYLTVP---------ARYLAMNKLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQI------DFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKG------LAPEVADRIGDYVQQHGGVSLVELDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGVERIFSIVEQR---------TETQVLVASAQKKL------LEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLV-AIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ.............................. 515
29 -22.6004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  13  8............................LRRQFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLKDQGELLSLRY--------LTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQI------DFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKG------LAPEVADRIGDYVQQHGGVSLVELDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGVERIFSIVEQR---------TETQVLVASAQK------KLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLV-AIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ.............................. 462
30 -22.6003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  11  10......PRGSHMNIAVLPNSPDTAPQIADPLDHLSMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVSLSPADLVLSPAACYPVYPIAASRGPL----PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGL------TFRVDYAS-------DPFFGRVGQMKAVSQKQQQL------------------------KFELLIPLRSE--EQPTACMSFNY--HFGTTWGIQDANGE--------PAHTGCVAGMDRLAVAMFHTHGTDLSAWPAKVRDIL................................................................................................................................ 324
31 -22.5003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  14  1............MAMGTLEAQTQGPGSMQMNMVETEPVQGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARQLLAKGRSL----LLPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIIGVKSVSSE-----VELVCAACTAMQSLGLSSKDVGVKINSRKILQTVVEQAGVSADKFAPVCVIVDKMEKLPREEVVAQLAAIGLESNVVDAIT-ELRDFITQIEAYGFGDWVIFDASVVR--GLAYYTGIVFEGFDRDGNFRALCGGDCVIVELLNEK--KLLPELHHVVDDLVIPFDETM------RPHALSILRRLRDAGRSADIVFDKKK-VVQAFNYADRIGALRA-VLVAPDEWARGEVRVKMLREGAGREEGANERGIVLPVD................................. 447
32 -22.3004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  12  26................TAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSH-REAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVSLSPADLVLSPAACYPVYPIAASRGPL----PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGL------TFRVDYAS-------DPFFGRAGKMLANNQRDQQL------------------------KFELLIPLRSE--EQPTACMSFNY--HFGTTWGIQDANGE--------PAHTGCVAGMDRLAVAMFHTHGTDLSAWPAKVRDIL................................................................................................................................ 324
33 -22.2003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  14  1............MAMGTLEAQTQGPGSMQKNMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSL----LLPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIVGVKSVSAE-----VELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAG-DKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVGLAYYTGIVFEGFDREGKFRALCGGDCVIVELLQEK--RLLPDIPHVVDDVVIPFDESM------RPHALAVLRRLRDAGRSADIILDKKK-VVQAFNYADRVGAVRA-VLVAPEEWERGEVQVKMLREGTGKEEGGAERGFAVPLD................................. 447
34 -21.2001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  14  6......................................RGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARG---DVVQKEMYTFKDKDRSITLRPEGTAAVVRSYIE--HKMQGNPNQPIKLYYNGPMFRYERKQK-----RYRQFNQFGVEAIGAENPSVD--AEVLAMVMHIYQSFGLK-----HLKLVINSVGDMASRKEYNEALVKHFEPVEQVKAYLDDLGIPYTEDPNLVRG--------LDYYTHTAFELMMDNPNYDGAITTLCGGGRYN---LLELLDGPSETGI---GFALSIERLLLALEEE--GIELDIEENLDLFIVTMGDQAD------RYAVKLLNHLRHNGIKADKDYL-QRKIKGQMKQADRLGAKFT-IVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK.................................. 420
35 -21.0005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  58...EAPGSGEGSEALLEICQRRHF--LSGSKQQLSRDSGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVNK--RLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM--------------------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELL---------------------HMYPGNVSKLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGRGPT---LELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILF-TVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK............................ 483
36 -20.7002dq0_A mol:protein length:455 Seryl-tRNA synthetase  ali model follow..  13  156.................EWKPKLHVDLLEILGGADFSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIYKVEDED-------LIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEI------PYRVVNICTGDLGYVAAKKYDIEAWMPGQGKFREVVSASNCT-----------------------------------------DWQ-ARRLNIRFRDRTDEKPRYVHTLNSTAI-ATSRAIVAILENHQEEIPKVLWK..................................................................................................................................... 436
37 -20.5001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  14  10......................................RGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSGEELLQQTYSFVDKGGREVTLIPEATPSTVRMVTSR-----KDLQRPLRWYSFPKVWRYEEPQA-----RYREHYQFNADIFGSDSPEAD--AEVIALASSILDRLGLQDIYEIRINFSIIDRYHKISREEFVDQLRSAGIGEDGVSMIADLCSGTRGIDEMARITGKSSEEIARMAAVEDLLASYG----VKNVRYDFSIVR--GLSYYTGIVFEAYDRSGQFRAILGG--RYDNLASLMSGESVP---EKKSVYICRVGKINS------SIMNEYSRKLRERGMNVTVEIM-ERGLSAQLKYASAIGADFA-VIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHLISQATLE............................. 428
38 -20.5005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  13  10......................................KGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRA---DIVEKEMYTFFDKGESLTLRPEGTAGCVRALVEH----NLLRGATPRVWYMGPMFRYEKPQK-----RYRQFHQFGVETFGVATPDID--AELIMLTARLWKRMGVDHM----VQLELNTLGETDERTEYRNALVAFLNEHQQLQDYLTAAGIKFVINQKLVRGLDYYNKTVFEW----TTTALGSQGTVCA---------RYD-GLVGQLKGKADQSVPAVGFAMG-MERLLLLLEQV---------VRDCEAFLVAEPAYQ------SKALVLAEQLRDQLEAANSNIRSQGSMKSQMKKADQAGAVYA-IILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK.............................. 432
39 -20.4002dq3_A mol:protein length:425 Seryl-tRNA synthetase  ali model follow..  16  135.................DFEPKPHWEIGERLGILDFSGSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLYKCERDN-------LIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGADIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGL------PYRVVELCTGDLGFSAAKTYDIEVWFPSQNKYREISSCSNCE-----------------------------------------DFQ-ARRMNTRFKDSKTGKNRFVHTLNGSGL-AVGRTLAAILENYQQEVPEVLRD..................................................................................................................................... 415
40 -20.2002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  41...EAPGSGEGSEALLEICQRRHFLSGSKQQ--DSLLSGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVN--KRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM--------------------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELL---------------------HMYPGNVSKLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGRGPT---LELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILF-TVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK............................ 466
41 -20.1003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  14  2........................NAMAKNDKINFSTPSGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKG--PNRQAEKDKSGDTSEARALKFDQTVPLAAYIARHLNDL----TFPFARYQMDVVFRGERAKD-----RFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNI------DFVIRINNRKVLTGFFQSLNISETQIKSCISIIDNLEKIGEAKVKLELEKEGINPEQTQKIIDFVKIDGSVDDVLDKLKHLQFNLGVSELETVITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTGGRYEELVTPAQVVVVNMQD------ELMPTYLKVSQQLRQAGLNVITNFEKRQ-LGKQFQAADKQGIRFC-VIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRLT............................... 465
42 -19.7004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  13  1MAMGTLEAQTQGPGSMTEQKRKLEK---------LTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGEVTDIVEKEMYSFVDAGENLTLRPENTAAVVRAAIEH----NMLYDGPKRLWYIGPMFRHERPQR-----RYRQFHQVGVEALGFAGPDAD--AEIVMMCQRLWEDLGLT-----GIKLEINSLGLAEERAAHRVELIKYLEQHEGLQRLLKANNVPFTINPRLVRGLDYYNLTVFEW----VTDKLGAQGTVAA---------RYD---LIEQLGGKPTAAC---GWAMGIERILELLKEE---------EGVDVYVVHQGDAAR------EQAFIVAERLRDTGLDVILHCSADASFKSQMKRADASGAAFA-VIFGEDEVTNGTASVKPGEKSVQQSVPVESLTEFLINAMVATAEDGDD....................... 461
43 -19.5004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  10  34...EAPGSGEGSEALLEICQRRHF--LSGSKQQLSRDSGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVN--KRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM--------------------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELL---------------------HMYPGNVSKLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGRGPT---LELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILF-TVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNVAAALE..................... 466
44 -19.5004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  13  9......................................RGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGAATDIVRKEMFTFQDRGRSLTLRPEGTAA---MVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQK-----RYRQFHQVNYEALGSENPILD-----AEAVVLLYECLKELGLRRLKVKLSREALSEDSKERLELNPMRILDSKSERDQALLKELGVRPMLDFLGEEARAHL-------EVERHLERLSVPYELEP--LDYYVRTAFEVHHEEIGAGGPRVPGV---GFAFGVERVALALEAE--GFGLPEEKGPDLYLIPLTEEAV------AEAFYLAEALRP-RLRAEYAL-APRKPAKGLEEALKRGAAFA-GFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG............................... 423
45 -19.2002el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  11  17.......................................GMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRA---DVVEKEMYTFEDRGDSLTLRPEGTAGCVRAGIEH----GLLYNQEQRLWYIGPMFRHERPQK-----RYRQFHQLGCEVFGLQGPDID--AELIMLTARWWRALGISE----HVTLELNSIGSLEARANYRDALVAFLEQHAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEW----VTNSLGSQGTVCA---------RYD---LVEQLGGRATPAV---GFAMGLERLVLLVQAV--NPEFKADPVVDIYLVASGADTQ------SAAMALAERLRDELPGVKLMTNGGGNFKKQFARADKWGARVA-VVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG............................... 431
46 -19.1006blj_A mol:protein length:485 Serine-tRNA ligase  ali model follow..  14  179.................GYKCLKHIDIMRKLGGLATGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIAT---SEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGADTLGIFRVHQFEKIEQFVVTSPKDNKSW---------------------------------------------EMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWF-ADEGNEYRELVSCSTDYQ-TRRLEVKYGKSKKQGSEVEF-CHNSTLTATSRTLCCIVENYQTPVPEVLQP..................................................................................................................................... 467
47 -19.0003vbb_A mol:protein length:522 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  14  164.................VRKKYSHVDLVVMVDGFEGAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVIGKGSEKSDD-LIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSDTRGIFRVHQFEKIEQFVYSSPHDNKSW---------------------------------------------EMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQ-ARRLRIRYGQTKKMMDKVEF-VHNATMCATTRTICAILENYQTEVPEKLKEGLQELIPFVKPAPIEQE------PSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTD............................................................................ 513
48 -18.9003lsq_A mol:protein length:484 Seryl-tRNA synthetase  ali model follow..  13  171.................RAKLNHVSIMERLGMMDTSAGGRSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVMGEVAQLSQFDEELYQVSGDGDKKYLIAT---SEMPIAAYHRGRWFTELKEPLKYAGMSTCFRKEAGADTLGIFRVHQFDKIEQFVVCSPRQEESW---------------------------------------------RHLEDMITTSEEFNKSLGLPYRVVNICSGALNNAAAKKYDLEAWFPASGAFRELVSCSNCTDYQ-SQSVNCRYGPNLRGTANVKEYCHNGTLCAITRTMCCICENYQTEIPDVLRP..................................................................................................................................... 459
49 -18.9003err_A mol:protein length:536 fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus  ali model follow..  16  239.................SFPPLDHVALMEKNGWWEVSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETD-------LTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASD---------------------------------------------RAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQ-ARRANLRYRDPEGRVRYAYTLNNTAL--ATPRILAMLLENHQLQVPQALIP..................................................................................................................................... 519
50 -18.5001ser_A mol:protein length:421 PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))  ali model follow..  16  115...EANREIKRVGGPPEFSFPPLDHVALMEKNGWWESGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETD-------LTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASD---------------------------------------------RAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQ-ARRANLRYRDPEGRVRYAYTLNNTAL--ATPRILAMLLENHQLQVPQALIP..................................................................................................................................... 410
51 -18.3001wle_A mol:protein length:501 Seryl-tRNA synthetase  ali model follow..  13  176.................SFQPRGHLEIAEKLDIIRQSGHRSYYLRGAGALLQHGLVNFTLNKLIHRGFTPMTVPDLLRGVVFEGCGMTPNAKPSQIYNIDPSRFEDL--LAGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETD-EPWGLYRVHHFTKVEMFGVTGPGLEQSS---------------------------------------------ELLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQ-SRRLHIMFQTEAGELQFAHTVNATGC--AVPRLLIALLESYQQKVPPALQP..................................................................................................................................... 460
52 -18.1001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  10  16...DAPEHAVAREALVDLCRRRHFLSGTPQQLSTAALLSGCHAFGPLGVELRKNLASQWWSSMFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESFLENLLKTSGKLRATLLHGALEHYVNCLDLVNR--KLPFGLAQIGVCFHPVSNSNQSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAM--------------------------SPSNFSSADCQDELGRKGSKLYYSFPWGKEPIETLWNLGDQELL---------------------HTYPGNVSTIQGRDGRKNVVPCVLSVSG--DVDLTLAYLYDSFQ-KLHPCLAPIKVALDVGKGPT---VELRQVCQGLLNELLENGISVGYSETVHSSLEQLHSKYDEMSVLF-SVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNVAAALD..................... 448
53 -17.4002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  15  48MGFSDALSRDRAFQGIEHQLMSQGK---RHLEQ---------LRTVKHRPALLELEEKLAKALHQQGFVQVVTPTIITKSALAKMT--GEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLW----DKPIRIFEIGTCYRKESQGA----QHLNEFTM--LNLTELGTPLEERHQRLEDMARWVLEAAGIR-----EFELVTESSVVYGDTVDVMKGDLELASGAMGPHFLDEKWEIFEGTQHVQSMARSLSYGVRLNIN............................................................................................................................................................................................................... 302
54 -17.4005c53_B mol:protein length:903 Pol gamma B  ali model follow..  10  59....APGSGEGSEALLEICQRRHFLSGSKQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTVVFREQVFPVDALHHKPGPLLPGDSAFRKLRENLLHGALEHYVNCLDLVN------------------KRLPYGLAQIGVCFHPVFDTKQNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM--------------------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELL---------------------HMYPGNVSKLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGRGPT---LELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILF-TVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNVMRS....................... 455
55 -17.3003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  2................................................................RSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTPGDSAFRGGLRENLLHGALEHYVNCLDLVNK--RLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM--------------------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELL---------------------HMYPGNVSKLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGRGPT---LELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILF-TVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK............................ 451
56 -17.1003w3s_A mol:protein length:527 Type-2 serine--tRNA ligase  ali model follow..  13  206................................VKEFPGRGQWIYTPPMAALFEVLRDFLLERVRKLGFEPALFPKLIPLETMFRMRYLHGLPDGMYYVKLRDPGYVLAPAQC-----FYELLRDEVVDPERLPIKLYDCGWTYRWE-GGAAKGLERVNEFQRIEHVWIAEPEEAYRIRRELLEATKRVAEELE---------------------------------------------------LEWKVVVSDDPFYLEGRLLEDRDIELPDVPSY-----EFEVYLPFK---ERSSEEAWISVGSFNVHGEHFVGVTRWVVGLLAQHGFYPYEWPEPILERIDEKFGGLPEVPKTLTWPE.............................................................................................................. 527
57 -17.0002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  13  19.............................................................................................................................................................................................................................................................................................GLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK--ALEEKIRTTETQVLVASAQKK------LLEERLKLVSELQDAGIKAELLYKKNPKLLNQLQYCEEAGIPLV-AIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPL............................ 167
58 -16.4004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  13  13......EVLLNPKDEISLNSGKPFRELESELLSRRKKD----IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRAL----PDPIKIFEIGPCYRKESDGK-----HLEEFTMLNFCQMGSGCTRENLESIITDFLNHL----------GIDFKIVGDSCMVFGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPW---IGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNL.......................................................................................................................................................................................... 268
59 -15.7004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  13  3LTKSQTDRLEVLLNPKDEISLNSGKPFREESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMVAPNIFNYARKLDRAL----PDPIKIFEIGPCYRKESDGK----EHLEEFTMLNFFQMGSGCTRENLESIITDFLNHL----------GIDFKIVGDSCSVYGDTLDVMHGDLELSSAVVGPIPLDREWGID----------PWIGAGFGLERLLKNIKRAARSESYYNGISTNL.......................................................................................................................................................................................... 267
60 -15.7003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  12  15.......................................GMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVS--AILDQQLFKLDQQGNTLVLRPDMTAPIARLVASSLKD----RAYPLRLAYQSNVYRAQQNEG-----KPAEFEQLGVELIGDGTASAD-----GEVIALMIAALKRAGLSEFKVAIGHVG-------NALLMDVVGNEQRADRLRRFLYEKNYVGYREHVKSLNLSTIDKSRL-LSLRGGRAAIEEARGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSYYTGVVFEGYGGRYDELLSGHEQTCILFSNERRFE------AIELARKKRANGEAVVLQDLAGV-TDVDAMSSNYQDVIYC-IGTAGRGGEDA............................................................ 400
61 -15.3004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  15  30......EVLLNPKDEISLNSGKPFRELESELLSRRKKD---QIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPD----PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGI..................................................................................................................................................................................................................................................................................... 203
62 -15.2003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  13  18LTKSQTDRLEVLLNPKDEISLNSGKPFELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPD----PIKIFEIGPCYRKESDGK----EHLEEFTMLVFWQMGSGCTRENLESIITDFLNHL----------GIDFKIVGDSCMVFGDTLDVMHGDLELSSALVGPIPLDREWGIDKPWIGAGFGLERL---LKVKHDFKNIKRAARSESYYNGISTNL.......................................................................................................................................................................................... 282
63 -14.8005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  13  10...DRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQ-QIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD----PIKIFEIGPCYRKESDGK----EHLEEFTMLAFAQMGSGCTRENLESIITDFLNHL----------GIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGID----------PWIGAGFGLEHDFKNIKRAARSESYYNGISTNL.......................................................................................................................................................................................... 268
64 -12.6002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  13  30......EVLLNPKDEISLNSGKPFRELESELLSRRKKD----IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD----PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLG------IDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPW---IGAGFGLERLLKVKHDFKNIKRAARSGSYYNGISTNL.......................................................................................................................................................................................... 285
65 -12.2003rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  14  2.............NAMNGTRSAWGARAWEAVRGFADRPPGMQDGYPDFAKRRRAVETRLLSFVEDAGYEPVTSGLFEYVDTLLRARSPESSRDWIRLFDGGGDAVALRPEMTPSIARMAAPRVAA----GRTPIRWCYCERVYRRTDDPASLSWAKAAESTQVGIERIGEEASVDVDM----DVLRLLHEASAAAGVRHHRIVVSHAR-------PRLLDALGISASLSRAFLACLTSGNYVQFRELWQLHAAKDVDLLANLLTWSPAERDAAKRSRRAAADVRDAWRYLCRLAEALHDSGLASDVVTFDLALHRELDYYTGLVFEMFAPG--------------VGAPIAQGGRYDELLAQFGAGAPAVGFAFEVE.............................................................................................. 357
66 -11.6004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  16  65..........................................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD----PIKIFEIGPCYRKESDGK----EHLEEFTMLSFIQMGSGCTRENLESIITDFLNHL........................................................................................................................................................................................................................................................................................... 201
67 -11.4001z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  14  9...........................GRMEKINYLLPEESAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMPPSFEYTQLYTESNGKTFNQEKMFQFKHEGQSITLRYDFTLPLVRLYSQIK------DSTSARYSYFGKIFRKEKRHK-----RSTENYQIGIELFGESADKSE-----LEILSLALQVIEQLGLNKTVFEI--------GSAKFFQRLCQLADGSTELLTELLLKKDLSGLNAFIEKNNFSK----RGLLKEIFITNELSRLENLVTNTKDDVLISSFDQLKEFSEKLSMIKPIIIDLGMVPKMDYYTDLMFKAYSSA--------------ANQPILSGGRYDQLLSNFQEEAFAIGFCCHMD.............................................................................................. 322
68 -11.0006FTT Entity 1(prereleased)  ali follow..  13  6.......................................GVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIQLTGRLMGIRADITPQILRIDAHHG------GDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD-----IELIDVLFSMINSLDMSA-VLHVDLGHVT-----KRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGS----TLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDGMKSNQLARLLAHTQLDAPFSAQRQLLLQQVASLRQQGYRVTMPLTAEDGLTHRLSLADNQWRLHAV....................................................................... 388
69 -11.0005m8h_A mol:protein length:388 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  13  6.......................................GVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIQLTGRLMGIRADITPQILRIDAHHG------GDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD-----IELIDVLFSMINSLDMSA-VLHVDLGHVT-----KRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGS----TLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDGMKSNQLARLLAHTQLDAPFSAQRQLLLQQVASLRQQGYRVTMPLTAEDGLTHRLSLADNQWRLHAV....................................................................... 388
70 -9.8201usy_A mol:protein length:275 ATP PHOSPHORIBOSYLTRANSFERASE REGULATORY SUBUNIT  ali model follow..  10  3.................................................FLDFEKVFSFYSKATKKGFSPFFVPALEKAEEPAGNFFLDR----------KGNLFSIREDFTKTVLNHRKRYS------PDSQIKVWYADFVYRYSGS-------DLVAEYQLGLEKVPRNSLDDS-----LEVLEIIVESASEFFEGPVIVEIGHTGVYED---------KEIPKDLHEKVLNLIDTKNLAEIEFLSHMKKIDLSRVEKI----IEDSIYRRSPEHLKTMDLPLSVREDLLSASSFLQEKFPTVSVEIDLTLARTIEEYCGLIFTIYGGEYTVNGEKGVGGSIFLEG........................................................................................................................... 272

FFAS is supported by the NIH grant R01-GM087218-01
1 2 7 7 6 3   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.