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Query: 3ial_A mol:protein length:518 Prolyl-tRNA synthetase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAMGGDVTFSLTKTRDTFADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVIPESFLKKESDHIKGFEAECFWVEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNTKPLIRVREIHWNEAHCCHATAEDAVSQLSDYWKVIDTIFSDELCFKGQKLRRVCWDRFPGADYSEVSDVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKANESVHPYLTCAGISTRVLACALSIHGDSGGLVLPPLIAPIHVVIIPIGCGKKNNQESDQQVLGKVNEIADTLKSKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDVGKDQKRVIPITEVMKVSSHTTENHELVVKNVIKDELDAYKARLKEKAFAFHNSMVTNCKSFDEIVACIENKGGLARFPFYTTEADGEVWDKKLKDACSAEIRGHNPDENVLPGEVCALSGKPAVCYMYCAKSYLast
1 -170.0003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model  100  1MAMGGDVTFSLTKTRDTFADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVIPESFLKKESDHIKGFEAECFWVEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNTKPLIRVREIHWNEAHCCHATAEDAVSQLSDYWKVIDTIFSDELCFKGQKLRRVCWDRFPGADYSEVSDVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKANESVHPYLTCAGISTRVLACALSIHGDSGGLVLPPLIAPIHVVIIPIGCGKKNNQESDQQVLGKVNEIADTLKSKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDVGKDQKRVIPITEVMKVSSHTTENHELVVKNVIKDELDAYKARLKEKAFAFHNSMVTNCKSFDEIVACIENKGGLARFPFYTTEADGEVWDKKLKDACSAEIRGHNPDENVLPGEVCALSGKPAVCYMYCAKSY 512
2 -139.0005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  29  8............KKSTNFADWYTQVIVRGELVEY-YDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKEKDHVEGFKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFKETG----GMEIVAKCRELERLL-NAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEAR--NVPWAEAASTIP---------------AMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRH-VVLAPWCEDPETETQIKRETQRLSAMKPLCIPFDQPPPEGTRCFFTGRPAKRWCLFGRSY 498
3 -139.0004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  29  1..MASNILGITSKKIENFSDWYTQVIVKSELIEY-YDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGAFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTD----ENAIHSYCKDIEKIL-KNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKC--NVKKESVLLETQ---------------QMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKK-MVLAPWCEDIATEEEIKKETQRLSAMKPLCIPLDQPPPPNMKCFWSGKPAKRWCLFGRSY 500
4 -138.0005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  31  7............KKDENFSEWYTQAIVRSEMIE-YYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEKDHVEGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDEN----TGEILGKCRELKTML-EKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQ--ISWADLAPKLL---------------ELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKH-LVLAPWCEDPESEEQIKKETQKLSAMKTLCIPFDQPPPEGTKCFYTGKPAKRWTLWGRSY 500
5 -137.0004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  27  25.PKKQTRLGLEAKKEENLADWYSQVITKSEMIEY-HDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRL-LSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKL--TVAENEAETKLQ---------------AILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGK-IVQIPFCGEIDCEDWIKKTTARDMGAKSLCIPFKPLCQPGAKCVCGKNPAKYYTLFGRSY 529
6 -136.0005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model follow..  29  4.KENESLLGITADKITSFADWYSQVIVKSEMIEY-YDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEKDHVEGFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVI----TEEQKKICNEVECIL-KKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKM--DIPISELESKIP---------------KLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKK-MVIAPWCEDVSCEEEIKKETARLGAMKSLCIPNDQIEEGKTKCFFCDKLAKKFTLFGRSY 505
7 -135.0004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  27  9.PKKQTRLGLEAKKEENLADWYSQVITKSEMIEY-HDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFIASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFANSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRRRL-LSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKL--TVAENEAETKLQ---------------AILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGK-IVQIPFCGEIDCEDWIKKTTARDMGAKSLCIPFKPLCQPGAKCVCGKNPAKYYTLFGRSY 513
8 -130.0001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  34  18.PIKKDPNRYHGEKMTEFSEWFHNILEEAEIIDQRYPVKGMHVWMPHGFMIRKNTLKILRRILDR-DHEEVLFPLLVPEDELAKEAIHVKGFEDEVYWVTHGGLSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKHTRPIRVREITTFKEAHTIHATASEAEEQVERAVEIYKEFFNSLG-IPYLITRRPPWDKFPGSEYTVAFDTLMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEYVHQTCYGLSDRVIASVIAIHGDESGLCLPPDVAAHQVVIVPIIFKKAA-----EEVMEACRELRSRL-EAAGFRVHLDDR-DIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKV--TADLQGIEETLR---------------ELMKDILENLRTRAWERMESEIREAETLEEASRIVDEKRGIISFMWCGEEECGMDVEE----KVRVDILGIQEEGS----GTCINCGREAPYRAYLARTY 495
9 -126.0005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  27  7...........AKREENFSAWYIDVITKAEMIE-YYDVSGCYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSCLEREKDHIEGFAPEVAWVTRAGDTELEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHPTPFIRTREFLWQEGHCAWAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVETFIAVGRGCQGATSHNLGQNFGKMFDIRFQDPENNEQTLIPNSWGLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESEL-CEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARH--SVAWDAQTPAA--------------VAALLEDVHAQMYARAKETMETHRVRVTEWTEFVPTLNRKC-LILAPWCGAMECENQVKKDSAEEMGAKTLCIPFEQPEEHECICKGCTKPATTWVLFGRSY 512
10 -125.0001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  31  7..........LTPQSQDFSEWYLEVIQKAELADYG-PVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLRKEAEHVEGFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTR-PFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESR-----ERVLEAAQGLRQAL-LAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKET---LPLAALPEALP---------------GKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQE--GFALAFHCGDKACERLIQE----ETTATTRCVPFEAEP-EEGFCVRCGRPSAKRVVFAKAY 477
11 -125.0001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  39  1...........GSHMLEFSEWYSDILEKAEIYDVRYPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAKEAEHIKGFEDEVYWVTHGGKTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMFKEAHTAHSTKEEAENQVKEAISIYKKFFDTLG-IPYLISKRPEWDKFPGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAYQTCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGKE-----DIVMEKAKEIYEKL--KGKFRVHIDDR-DIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQ--VDETQLMEVVE---------------KTLNNIMENIKNRAWEKFENFITILEDIDEIKNILSEKRGVILVPFKEEIYNEELEEK-----VEATILGETEYK----GNKYIAIA----------KTY 459
12 -88.4002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  19  1MKQSKMLIPTLREVPNDAEVLSHQILLRAGYI--RQVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAEL-WKESGRYETYGPNLYRLK----DRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSRSGLLRGREFIMKDGYSFHADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKEFMAISEILAFTKGIEIGHIFKLGTRYSDAMGATVLDENGREKSVIMGCYGIGSRLLSAIVEQNADERGINWPTGIAPFDLHVVQMNVKDEYQTKLSQEVEAM--------MTEAGYEVLVDDR-NERAGVKFADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEMLE--VRKEELESTLSILMNTTSEV.......................................................................................................... 571
13 -83.0002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  19  15MRLSRFFLPILKENPKEAEIVSHRLMLRAGML--RQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLADL-WRESGRYDAYGPEMLRIA----DRHKRELLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDVDEAGARKSYNKMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHESEVPEANRLNTRGIEVGQIFYFGTKYSDSMKANVTGPDGTDAPIHGGSYGVGSRLLGAIIEACHDDNGIIWPEAVAPFRVTILNLKQGDAATDAACDQLYRE--------LSAKGVDVLYDDT-DQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGAREN--LALADVVARLT................................................................................................................... 452
14 -78.8005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  21  3MRTSQYLLSTLKETPADAVVISHQLLLRAGMI--RRLASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQPAEL-WQESGRWEQYGPELLRLK----DRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQADNGSIGGSGSHEFHVLANSLVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGSRVVAAAIEQNHDERGILWPSALAPFQIALVPLKYETESVKQATDKLYAE--------LTAAGFEVLLDDRDKKSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQN--LPIGELMSFITEKLSR.............................................................................................................. 573
15 -69.4004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  16  1.............MGSSSSGDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRL-WMTSGHWQHYSENMFSF-----EVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALGLTRVRRFQQDDAHIFCAMEQ-IEDEIKGCLDFLRTVYSVFGSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDKKRPVIVHRAILGSVERMIAILTENYGG-KWPFWLSPRQVMVVPVGPTCDEYAQK-----------VRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRD--NKVHGERTISETIERLQQLKEFRSKQAEEEF..................................................................................................... 409
16 -67.9004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model follow..  16  1.................MARDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRL-WMTSGHWQHYSENMFSF-----EVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALGLTRVRRFQQDDAHIFCAMEQ-IEDEIKGCLDFLRTVYSVFGSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKRPVIVHRAILGSVERMIAILTENYGG-KWPFWLSPRQVMVVPVGPTCDEYAQK-----------VRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRD--NKVHGERTISETIERLQQLKEFRSKQAEEEFLE................................................................................................... 407
17 -64.9003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model follow..  12  3SGQDKTHIDYAYELDITVKPDSRVPVFNREFATF--TGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTEL-FKVSGHIEFYRNNMYLF-----DIEGHEFAVKPMNCPYHILLFLNEVASKLPLPFKVFEFGRVHRYEPSGSIGLLRVRGFTQDDAHIIVPGGR-VIDVVYDVFEEMKLVLERLFKLGVSGIDIVELEGEAAFYGPKLDMVEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREFGIEEVYIIHRALLGSIERFLGVYLEHRRG-RMPFTLAPIQFAVIAVKTGGEVDREIEDLASSIAKGL-----LDKGFRVAVKGSSKTGLSSDVRHIESTAKPAVVFIGAKEVREKVLDVRVFD--LESMKRRRLAIAYGDAADAVENLAAVAEELESPVRS................................................................................................ 455
18 -63.8004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model follow..  15  1.................MARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVL-WEKTGHWDNYKDAMFTT-----SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLGLMRVRGFTQDDAHIFCTEEQ-IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAG-FFPTWLAPVQVVIMNITDSQSEYVNE-----------LTQKLSNAGIRVKADLR-NEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRR--GKDLGSMDVNEVIEKLQQEIRSRSLKQLEELE.................................................................................................... 405
19 -63.2003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model follow..  16  21...........NASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKKFGFNEVVTPLIYKKTL-WEKSGHWENYADDMFKVET--TDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALGLTRLRKFHQDDGHIFCTPSQ-VKSEIFNSLKLIDIVYNKIFILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEG-RWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEVPLNDWHFNVDLDIR-NEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERD-NRKSFEKLTMSQIWEKFIELEKNYK............................................................................................................ 454
20 -60.7001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  18  222FFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDL-YKTSGHWDHYQEDMFPPMQ---LDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVGLQRVRGMTLNDSHIFVRPDQ-IKEEFKRVVNMIIDVYKDFGAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKG-AFPTWLAPKQVQIIPVNVDLH---------YDYARQLQDEL-KSQGVRVSIDDR-NEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYG--SQDQETVEKDEFIWNLVDEIRLKKHR.......................................................................................................... 645
21 -58.2001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  15  223WADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVL-WEKTGHWDNYKDAMFTT-----SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSHGLMRVRGFTQDDAHIFCTEEQ-IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAG-FFPTWLAPVQVVIMNITDSQSEYVNE-----------LTQKLSNAGIRVKADLR-NEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRR--GKDLGSMDVNEVIEKLQQEIRSRSLKQLEE...................................................................................................... 642
22 -49.0001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  14  1..........AASSLDELVALCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRLV-LHYSGHEATFADPMVDNAKARYGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRPGE-DEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYRELEGIAQRTDFDLGSHTKDQEALGITARVLRNEYVIEPSAGVDRGVLALLAEAFTREE-LKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKAR--------LLALGLGRVLYEDTG-NIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIR--LHVDELEGFLRERLR............................................................................................................... 441
23 -39.0002cim_A mol:protein length:522 SERYL-TRNA SYNTHETASE  ali model follow..  16  179.AEHWNLLWQREPMEHPFKEDPTQAMMKEGWLK-RGSSRGQWIHGPQSARIFRTFEKIVLEELEPLGYREMIFPKLVTWEVW-MKSGHAKGVYPEIYYVCPPQTRDAEPIGGMCYAQCPPFWMYVAGETLPNEEIPVKVFDRGTSHRYESGGIHGIERVDEFHRIEIVWI-GTKEEVLKCAEELHDRYMHIFNDILDIEWRKARVTPWFMAQEGLLGLAEENTVPDGEWLEFQNVSINGDKYPKGFNVKLQSGD----ELWSGCSGVGERWAAVFLAQKGLDPA-NWP---EEFRNRVGEMPKGIR.............................................................................................................................................................................................................. 514
24 -36.0001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  15  1..............AASSLDELVALCKRRGFIFQSSEIQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRLV-LHYSGHEATFADPMFQDLRGPRGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRPGE-DEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYR----FPHGSLELEGIAQRTDFDLGSHTKDQEALYVIEPSAGVDRGVLALLAEAFTREE-LKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKAR--------LLALGLGRVLYEDTG-NIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIR--LHVDELEGFLRERLR............................................................................................................... 504
25 -35.8002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  14  49RVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAISGLYDFGPVGCALKNNIIQTWRQHFQEEQILEIDCTMLTPEPVL-KTSGHVDKFADFMVKDVKNGEGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVISFGLGRIMYTVFEHTFHVREGFSFPAVVAPFKCSVLPLSQN--------QEFMPFVKELSEAL-TRHGVSHKVDDSSG-SIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNIT--------------ADVEARYPLFEGQETGKKETIEELE.................................................................... 687
26 -30.7003qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  10  134.ENYKKPEQIAAATGAPAKLSHHEVLLRLDGYDPERGVHRGYFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVM-AKTAQLSQFDEELYKVI----DGEDEKYLIATSEQPISAYHAGEWFSPAEQLPVRYAGYSSCFRREAKDAWGIFRVHAFEKIEQFVLTEPEK-SWEEFDRMIGCSEEFYQSLGLPYRVVGIVSGELNNAAAKKYDLEAWFPFQQEYKELVSCSNCTDYQSRNLEIRCGIKQQNQQHCLNSTLSATERTICCILENYQKEDGLVIPEVLRKY----------------PGEPEFIPYIKELPKNTTSVKKAKGKNPK-NTTSVKKAKGKNGSR............................................................................................................................................................. 479
27 -28.5004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  15  11.RGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALIT-SHREAGTEALRFPPVMSRAQL-EKSGYLKSFPNLLGCVCGLHGTEREADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRRE--PSKHLDRLQSFRMRE-YVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDGKMLANNQRDQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGE----PAHTGCVAFGDRLAVAMFHTHGTDLS-AWPAKVRDI.......................................................................................................................................................................................................................... 323
28 -28.0002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  11  31AELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPV-LHHKPGPLLPGDSAFRLVSAETLQLVTFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQGVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYN---ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLE------NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEM--MHISKLKDFLIKYISSAKN........................................................................................................... 467
29 -27.8005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  11  49.ELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLL-PGDSAFRLVSAETLQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQIVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYN--KELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLE------NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEM--MHISKLKDFLIKYISSAKN........................................................................................................... 484
30 -27.8003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  15  11.RGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQL-EKSGYLKSFPNLLGCVCGLHGTEREADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRRE--PSKHLDRLQSFRMREY-VCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDGQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGE----PAHTGCVAFGDRLAVAMFHTHGTDLS-AWPAKVRDI.......................................................................................................................................................................................................................... 323
31 -27.3004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  11  25.ELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPV-LHHKPGPLLPGDSAFRLVSAETLQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKNGVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYN---ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLE------NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEM--MHISKLKDFLIKYISSAKN........................................................................................................... 460
32 -25.6001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  11  7.GPADGTQQPDAPEHAVAREALVDLCRRRHFLSGTPQQSGCHAFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHQEP-SQPRDSAFRLVSPESEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNKLPFGLAQIGVCFHNSNQTPSSVTRVGEKTEASLVWF-TPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYS---EPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSGDVDLGTLAYLYDSFQLAENLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLE------NGISVWPGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEM--MHISKLRDFLVKYLASASN........................................................................................................... 442
33 -23.7003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  10  56HPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDAL-------------------HHKPGPLLPGDSAFRGGLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQIVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYN--KELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLE------NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEM--MHISKLKDFLIKYISSAKN........................................................................................................... 452
34 -22.9001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  12  7...................................EKIRGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSG--EELLQQTYSFV----DKGGREVTLIPEATPSTVRMVTS--RKDLQRPLRWYSFPKVWRYE-EPQAG--RYREHYQFNADIFGSDSPEADAEVIALAFSVFSIIDRYHKISREEFVDQLRSAGIGEDGVSMIADLCSGTRGIDE-KNVRYDFSIVRGLSIVFEAYDRSGQFRAILGGGRYDNLASLMSGESVPAVGFGM-IPREKKSVYICRVGKINSSIMNE-----------YSRKLRERGMNVTVE--MERGLSAQLKYASAIGADFAVIFGERDLERGVVTIRNMYTGSQEN--VGLDSVVEHLISQATLE............................................................................................................. 428
35 -22.8001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  12  3...................................KIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGD-DVVQKEMYTFK----DKGDRSITLRPEGTAAVVRSYEHKMQGNPNQPIKLYYNGPMFRYE-RKQKG--RYRQFNQFGVEAIGAENPSVDAE---VLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALLDIEENLDLFIVTMGDQADRYAVK-----------LLNHLRHNGIKADKD--LQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESET--IELDALVEYFKK.................................................................................................................. 420
36 -22.4004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  9  32LKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGE----SKLIYDLK----DQGGELLSLRY-----LTVPFARYLAMNKLTNIKRYHIAKVYRRD-NPAMTRGRYREFYQCDFDIAGNFDPMIPDA--ECLKIMCEILSSLQIGDFLVKVNDRRQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARIYEAVLLQTPAQAKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLK-----------LVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKL--RSVTSREEVDVRREDLVEEIKRRTGQ.............................................................................................................. 515
37 -22.1003vbb_A mol:protein length:522 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  13  167..................KYSHVDLVVMVDGFEGEKVVAGSYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVM-QEVAQLSQFDEELYKVIGKGSEKSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVRDTRGIFRVHQFEKIEQFVYSSPHNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDHMLNATMCATTRTICAILENYQTEKGITVPEKLKEFLQELIP-SKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDALE............................................................................................................................................................................... 516
38 -22.0003w3s_A mol:protein length:527 Type-2 serine--tRNA ligase  ali model follow..  17  208..................................EFPGRGQWIYTPPMAALFEVLRDFLLERVRKLGFEPALFPKLIPLETM-FRMRYLHGLPDGMYYVCPPKRDPEDPGYVLAPAQCEPFYELLRDEVVDPERLPIKLYDCGWTYRWEGGAAKGLERVNEFQRIEH-VWIAEPEEAYRIRRELLEATKRVAEELELEWKVVVSDPDVPSYEFEVYLPFKGERSSEEAWISVGSFNVHGEHFVDGFNVK--EKSGRTLFTGCAGLGV-TRWVVGLLAQHGFYPY-EWPEPI............................................................................................................................................................................................................................. 505
39 -21.6003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  13  24...................................EPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAG--EEITEQMFNFI----TKGGHRVALRPEMTPSLARLLLGKGRSLL-LPAKWYSIPQCWRYE-AITRG--RRREHYQWNMDIVGVKSVSAEVE---LVCAACWAMRSLGLSSKDVGIKVNSRK-EEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAIVFEGFDREGKFRALCGGGRYDNLLTTYIPCAGFGFGDLLPDIPHVVDDVVIPFDESMRPHALA-----------VLRRLRDAGRSADII--DKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKE--EGGAERGFAVPLD................................................................................................................. 447
40 -21.5001ser_A mol:protein length:421 PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))  ali model follow..  15  115.EANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAF-LGTGHFPAYRDQVWAIA-------ETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAKDVRGLMRVHQFHKVEQYVLTEASEASDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLN--ATPRILAMLLENHQLQDGVRVPQALIPY.......................................................................................................................................................................................................................... 411
41 -21.5005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  14  7...................................VAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGD-DIVEKEMYTFFDKGNP--PESLTLRPEGTAGCVRALVEH-NLLRGATPRVWYMGPMFRYE-KPQKG--RYRQFHQFGVETFGVATPDIDAELIMLMGVDHMVQLELNTLGETDERTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKIDFLKEDSLSHF-YLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTAMERLLLLLEQVEQAEIVRDCEAFLVAEP-LAEQLRDQLEAANSNIRSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQ--VALAELVPFLIEKFTK.............................................................................................................. 432
42 -21.5004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  13  6...................................RAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGA-DIVRKEMFTFQ----DRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAE-RPQKG--RYRQFHQVNYEALGSENPILDAE---AVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLREVLSPHREARLSVPYELEPALVRGLDYRYDGLSELLGGPRVPGVGFAFGVERVALALEAEG---FGLPEEKGPDLYLIPLT----------EEAVAEAFYLAEALRPRLRAEYALAPR---KPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVR--LSREEVPGYLLQALG............................................................................................................... 423
43 -21.5001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  18  7...................................................................................................................................................................................................................................................................................................GPVDCSVIVVNKQTKDYAES-----------VGRKVRDLGMVVDLI-NTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQEHRNMPQADAMVLVARNYERYKNECREK...................................................................................................... 115
44 -21.3004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  10  15...................................KTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGE----SKLIYDLK----DQGGELLSLRY-----LTVPFARYLAMNKLTNIKRYHIAKVYRRD-NPAMTRGRYREFYQCDFDIAGNFDPMIPDA--ECLKIMCEILSSLQIGDFLVKVNDRRQNKQALEGLGDLKLLFEYLTLFGIDDKISFDLSLARIYEAVLLQTPAQAKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLK-----------LVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKL--RSVTSREEVDVRREDLVEEIKRRTGQ.............................................................................................................. 462
45 -21.3003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  15  24...................................EPVQGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLESEELYIRKAG--EEITEQMFNFI----TKGGHRVALRPEMTPSLARQLLAKGRSLL-LPAKWYSIPQCWRYE-AITRG--RRREHYQWNMDIIGVKSVSSEVELVCAADVGVKINSRKILQTVVEQAGVSADKFEEHEAVRELRDFITQIEAYGFGDWVIFDASVVRGLAIVFEGFDRDGNFRALCGGGRYDNLLTTYVPCVGFGFGDLLPELHHVVDDLVIPFDETMRPHALS-----------ILRRLRDAGRSADIV--DKKKVVQAFNYADRIGALRAVLVAPDEWARGEVRVKMLREGAGRE--EGANERGIVLPVD................................................................................................................. 447
46 -21.0002dq3_A mol:protein length:425 Seryl-tRNA synthetase  ali model follow..  14  139...................KPHWEIGERLGILDFKRGASRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEIL-IGTGQLPKFEEDLYKCE-------RDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAKDIRGIIRQHQFDKVELVKI-VHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTGDLGFSAAKTYDIEVWFPSQNKYREISSCSNCEDFQARRMNTRFKDSKTGKNRFVHTLNGSGGRTLAAILENYQQEDGVVVPEVLRDY.......................................................................................................................................................................................................................... 416
47 -20.8003err_A mol:protein length:536 fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus  ali model follow..  17  243...................LDHVALMEKNGWWEPRSQVSGSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAF-LGTGHFPAYRDQVWAIA-------ETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAKDVRGLMRVHQFHKVEQYVLTEASLESDRAFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTLN--ATPRILAMLLENHQLQDGVRVPQALIPY.......................................................................................................................................................................................................................... 520
48 -20.5002el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  12  4..........................YQDPMAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGE-DVVEKEMYTFE----DRNGDSLTLRPEGTAGCVRAGIEH-GLLYNQEQRLWYIGPMFRHE-RPQKG--RYRQFHQLGCEVFGLQGPDIDAELIMLLGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVFEWVTNSLGSQGTVCAGGRYGFAMGLERLVLLVQAVN---PEFKADPVVDIYLVASGADTQSAAMALAERLRD---------ELPGVKLMTN--GGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTA--VAQDSVAAHLRTLLG............................................................................................................... 431
49 -20.3002dq0_A mol:protein length:455 Seryl-tRNA synthetase  ali model follow..  16  160...................KLHVDLLEILGGADFARAASRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVE-EGSTSFEDFEDVIYKVE-------DEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAKDTKGIFRVHQFHKVEQFVY-SRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGKFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTASRAIVAILENHQEEDGVRIPKVLWKY.......................................................................................................................................................................................................................... 437
50 -20.3001wle_A mol:protein length:501 Seryl-tRNA synthetase  ali model follow..  15  180...................RGHLEIAEKLDIIRQKRHVSGSYYLRGAGALLQHGLVNFTLNKLIHRGFTPMTVPDLLRGVVF-EGCGMTPNAKPSQIYNI---DPSRFEDLNLAGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETKEPWGLYRVHHFTKVEMFGVTGPGEQSSELLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVN--AVPRLLIALLESYQQKDGVLVPPALQPY.......................................................................................................................................................................................................................... 461
51 -20.3003lsq_A mol:protein length:484 Seryl-tRNA synthetase  ali model follow..  15  167...........NTTKRAKLNHVSIMERLGMMDTSKASMAGGYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVM-GEVAQLSQFDEELYQVSGDGDK-----KYLIATSEMPIAAYHRGRWFTELKEPLKYAGMSTCFRKEARDTLGIFRVHQFDKIEQFVVCSPREESWRHLEDMITTSEEFNKSLGLPYRVVNICSGALNNAAAKKYDLEAWFPASGAFRELVSCSNCTDYQSQSVNCRYGPNLRGTAHMLNGTLCAITRTMCCICENYQTEEGVVIPDVLRPY.......................................................................................................................................................................................................................... 460
52 -20.2005c53_B mol:protein length:903 Pol gamma B  ali model follow..  10  56HPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPV--------------------DALHHKPGPLLPGDSAFRKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQIVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYN--KELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLE------NGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEM--MHISKLKDFLIKYISSAKNVMRSRVAVR-HKVCRCLLSGFGGRVDA................................................................................ 479
53 -19.5003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  11  13...................................STPSGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKGNQGDNIQAEKDKSG----DTGSEARALKFDQTVPLAAYIARHLNDLT-FPFARYQMDVVFRGE-RAKDG--RFRQFRQCDIDVVGREKLSLLYDA-QMPAIITEIFEAVNIGDFVIRINNRKSELETVITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTLIGHEALGSICSGGRYGISIGLTRLISRL--LKAGILNTLPPTPAQVVVVNMQDELMPTYLK-----------VSQQLRQAGLNVITN--EKRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSL--KDLQSGEQVEVALADLAEEIKRRLT............................................................................................................... 465
54 -19.3006blj_A mol:protein length:485 Serine-tRNA ligase  ali model follow..  16  175...........DPETGYKCLKHIDIMRKLGGLATEEQVGGGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQM-KKVAQLSQFDEELYTVTGE-----GEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKKFDLEAWFPGADE-ELVSCSNCTDYQTRRLEVKYGKSKKQGSHMLNSTLTATSRTLCCIVENYQTPEGVNVPEVLQPY.......................................................................................................................................................................................................................... 468
55 -18.8004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  15  6.KSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDT-------ELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLNFCQMGCTRENLESIITDFLNHL.................................................................................................................................................................................................................................................................................................................................... 184
56 -18.8004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  12  1MAMGTL---------EAQTQGPGSMTEQKRKLEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGIGE-DIVEKEMYSFVDALN---GENLTLRPENTAAVVRAAIEH-NMLYDGPKRLWYIGPMFRHE-RPQRG--RYRQFHQVGVEALGFAGPDADAE---IVMMCQRLWEDLGLTGIKLEINSLGLAEERAAHRVELIKYLEQHAD-ANNVPFTINPRLVRGLDYRYDPLIEQLGGKPTAACGWAMGIERILELLKEEHL-----PEQEGVDVYVVHQGDAAREQAFI-----------VAERLRDTGLDVILADGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPLRGTGDVQQSVPVESLTEFLINAMVATAEDGDD....................................................................................................... 461
57 -18.8005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  15  6.KSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-------DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGKE---HLEEFTMLAFAQMGSGRENLESIITDFLNHL.................................................................................................................................................................................................................................................................................................................................... 184
58 -17.8003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  15  19TKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-------DNDTELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLVFWQMGSGCENLESIITDFLNHL.................................................................................................................................................................................................................................................................................................................................... 198
59 -17.6004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  15  5.KSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQI-------FRVDKNFCLRPMVAPNIFNYARKLDRALPD-PIKIFEIGPCYRKESDGKE---HLEEFTMLNFFQMGSGRENLESIITDFLNHL.................................................................................................................................................................................................................................................................................................................................... 183
60 -17.6004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  14  22TKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-------DNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLNFCQMGSGCENLESIITDFLNHL.................................................................................................................................................................................................................................................................................................................................... 201
61 -17.3002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  15  39LNASGEQLEMGFSDALSRDRAFQGIEHQLMSQGKRHL----QLRTVKHRPALLELEEKLAKALHQQGFVQVVTPTIITKSALAKMTIGEDH---------FSQVFWLDGKKCLRPMLAPNLYTLWRELERLWDK-PIRIFEIGTCYRKESQGAQ---HLNEFTMLNLTELGTPLEERHQRLEDMARWVLEAAG............................................................................................................................................................................................................................................................................................................................... 217
62 -15.9003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  10  11...................................EKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVSAILD---QQLFKLL----DQQGNTLVLRPDMTAPIARLVASSLKD-RAYPLRLAYQSNVYRAQQNEG----KPAEFEQLGVELIGDGTASADGEVIALMSRLMNLLSLRGGRAAIEEARGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSVVFE--SGGRYDELLSKFHRPAQATGFGVRIDLLVEALNGEIISNGHEQTCILFSNERRFEAIE-----------LARKKRANGEAVVLQDLAG-VTDVDAMSSNYQDVIYCIGTAGRGGEDA.............................................................................................................................................. 400
63 -15.7002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  11  26TDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQ---IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-------DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGKE---HLEEFTMLNFCQMGSGCT-----RENLESIITDFLNHLGI........................................................................................................................................................................................................................................................................................................................... 203
64 -15.4002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  15  45.........................................................................................................................................................................................................................................................................GPDESKQKFVLKT---PKALEEKIRTTETQVLVASAQ----------KKLLEERLKLVSEL-QDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKL--RSVTSREEVDVRREDLVEEIKRRTGQPLS........................................................................................................... 168
65 -15.1006FTT Entity 1(prereleased)  ali follow..  7  5......................................DGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESLLSGAS--EDLKRQTFKIIDQLT---GRLMGIRA---DITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGL----GSRTPLQLGAEIFGCESIAADIELIDVL--------------------------------------FSMINSLDMSAVLHVDLGHVTIFKRLAELAALSASDTEQLMQLYANK-LKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHY-VFNGYINSETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHRLSLA........................................................ 379
66 -15.1005m8h_A mol:protein length:388 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  7  5......................................DGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESLLSGAS--EDLKRQTFKIIDQLT---GRLMGIRA---DITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGL----GSRTPLQLGAEIFGCESIAADIELIDVL--------------------------------------FSMINSLDMSAVLHVDLGHVTIFKRLAELAALSASDTEQLMQLYANK-LKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHY-VFNGYINSETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHRLSLA........................................................ 379
67 -14.5004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  14  65..........................................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDT---------SKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGKE---HLEEFTMLSFIQMGSGCT-----RENLESIITDFLNHLGI........................................................................................................................................................................................................................................................................................................................... 203
68 -13.4003rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  9  1...SNAMNGTRSAWGARAWEAVRGFA---------DRPPGMQDGYPDFAKRRRAVETRLLSFVEDAGYEPVTSGLFEYVDTLLRARS--PESSRDWIRLF----DGGGDAVALRPEMTPSIARMAAPRVAA-GRTPIRWCYCERVYRRTLSWASG--KAAESTQVGIERIGEEASVDVD--MDVLRLLHEASAAA-----------------GVRHHRIVVSHARLVPRLLDALGISASLSRAFLACLTSGNYVQFRELWQLHAAKDVDLLANLLTWSPAERDAAKRSREASDRELEALLRDAVDPRAAADVRDAWRYLCRLAEALHD-ASDVVTFDLALHRELDY-VFEMFAPGVGAPIAQGGR----DELLAQFGAGAPAVGFAFEVERVMAVLEAQEEGEGE........................................................................................................... 372
69 -12.0001z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  10  1MRGSGSIEGRMEKIN--------------------LLPEESAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMPPSFEYTQLYTALESNGKTFQEKMFQFI----KHEGQSITLRY---DFTLPLVRLYSQIKDSTSARYSYFGKIFRKEKRHK----RSTENYQIGIELFGESADKSELEILSLA....................................................................................................................................................................................................................................................................................................................................... 157
70 -10.6003g1z_A mol:protein length:326 Putative lysyl-tRNA synthetase  ali model follow..  13  17................................................LLKRAAIMAEIRRFFADRGVLEVETPCMSQATV---TDIHLFPFETRF----VGPGHSQGINLYLMTSPEYHMKRLLAAGCG-------PVFQLCRSFRNE---EMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHF----------------------PASQAS----LAQISTEDHRVAERFEELANGFHELTDAREQQQRFEQDNRKRAAQPIDQNLLDALAAGLPVMLALGAESLAD............................................................................................................................................... 317
71 -9.8603a5y_A mol:protein length:345 Putative lysyl-tRNA synthetase  ali model follow..  13  30................................................LLKRAAIMAEIRRFFADRGVLEVETPCMSQATV---TDIHLVPFETRF----VGPGHSQGMNLWLMTSPEYHMKRLLVAGCG-------PVFQLCRSFRNE---EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHF----------------------PASQAS----LAQISTEDHRVAERFEELANGFHELTDAREQQQRFEQDNRKRAAHPIDQNLIEALKVGMPVMLALGAETLAE............................................................................................................................................... 330
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.