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Query: 3ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRGGLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNVLast
1 -160.0003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model  100  1MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRGGLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV 453
2 -133.0005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  99  1MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV 485
3 -131.0002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  98  2.....................RGTMDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV 468
4 -127.0004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  98  1........................MDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV 461
5 -121.0005c53_B mol:protein length:903 Pol gamma B  ali model follow..  95  2...RSRVAVRACHKVCRCLLSGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSA-FRKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV 452
6 -119.0001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  77  9..................................................ADGTQQPDAPEHAVAREALVDLCRRRHFLSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQWWSSMVVFREQVFAVDSLHQEPGSSQPRDSKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYSFPWGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSFQLAENSFARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVWPGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASNV 443
7 -89.8001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  25  1.............................................................AASSLDELVALCKRRGFIFQSSEIYGGLQGV----YDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDNMMFQDLRGPRGGRGLLAYLRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITPR---NFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGRDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREEL----PNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKARLLALGLGR---VLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR..... 441
8 -85.0001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  19  57.RDDMEGLDASVLTHRLVLHYSGHEATFADPMVDNR--ITKKRYRLDHLLKEQPEEVLKRLYRAMEVEEENLHALVQAMMQAPE--------------------RAGGAMTAAGVLDPASGEPGDWTPFNMMFQDLRGPRGGRGLLAYLRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITP---RNFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGIDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREEL----PNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKARLLALGLGR---VLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR..... 504
9 -82.0002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  15  117QEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDV--KNGECFRADHLLKAHLQKLMSDKSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLM------------------------KTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRS---GLIRVREFTMAEIEHFVDPSEKNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEITEMEMLLNEKGEFTIETEGKTFQLTKDMINV-----KRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVRE------GDEQRTFFSFPAVVAPFKCSVLPLSQN-QEFMPFVKELSEALTRHGVSH---KVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTTATLRDRDSMRQIRAEISELPSIVQDLANGNIT. 661
10 -27.5004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  1........................MGSSSSGLVPRGSHMASGAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHD---------ISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHR-DLPIKLNQWCNVVRWEFKHPQP---FLRTREFLWQEGHSAATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEA---SASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMG------------LVLPPRVACVQVVIIPCEEDKEALIAKCNDYRRRLLSVNIRVRAD--LRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQV. 427
11 -26.8001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  11  1...............................MGSSSSGLVPRGSHMQKPIKKDPNRYHGEKMTEFSEWFHNILEEAEIID--------QRYPVKGMHVWMPHGFMIRKNTLKILRRILDRDHEEVLFPEDEVYWVTHGGLSKLQRKLALRPTSETVMYPMFALWVRSHT-DLPMRFYQVVNTFRYETKHTR--PLIRVREITTFKEATIHATASEAEEQVERAVEIYKEFFNSLGIP---YLITRRPPWDKFPGSEYTVAFDTLMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEYVHQT--CYGLSDRVIASVIAIHGDESG------------LCLPPDVAAHQVVIVPIKKAAEEVMEACRELRSRLEAAGFRV---HLDDRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVTADLQGIEETLRELMKDILE. 411
12 -26.7005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  6.........................................................TAKKSTNFADWYTQVIVRGELVEYYD---------ISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQATHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHR-DLPLKLNQWNNVVRWEFKQPTP---FLRTREFLWQEGHTAATEEEAYTLVLEILELYRQWYEDYLAVPV-IKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQ--LVHQTSWGCTTRSLGVMIMTHGDDKG------------LVLPPRVVAVQAVIIPIIFKETGIVAKCRELERLLNAAGVRVKVD--DRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQK. 393
13 -26.6004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  10  5..........................................................EGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHR-DLPIKLNQWCNVVRWEFKHPQP---FLRTREFLWQEGHSAATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEA---SASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMG------------LVLPPRVACVQVVIIPCGITNEALIAKCNDYRRRLLSVNIRVRAD--LRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQV. 411
14 -26.1004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  1.................................................MASNILGITSKKIENFSDWYTQVIVKSELIEYYD---------ISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYR-DLPLKLNQWNTVVRWEFKQPTP---FIRTREFLWQEGHTAKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFIS-ENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQY--VHQTSWGCTTRSIGIMIMTHGDDKG------------LVLPPNVSKYKVVIVPITTDENAIHSYCKDIEKILKNAQINCVYD--DRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHK. 396
15 -25.7005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  10  7...........................................................KKDENFSEWYTQAIVRSEMIEYYD---------ISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHR-DLPLKLNQWCSVVRWEFKQPTP---FLRTREFLWQEGHTAATEEEAWELVLDILELYRRWYEECLAVPVIKG-EKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKR--LVHQTSWGCTTRSLGVMIMTHGDDKG------------LVIPPRVASVQVVIIPIDENTGEILGKCRELKTMLEKADIRVRID--DRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQR. 392
16 -25.2001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  11  1..........................................................GSHMLEFSEWYSDILEKAEIYD--------VRYPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDTHGGKTQLDVKLALRPTSETPIYYMMKLWVKVHT-DLPIKIYQIVNTFRYETKHTRP---LIRLREIMTFK-TAHSTKEEAENQVKEAISIYKKFFDTLGIP---YLISKRPEWDKFPGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDK--DYAYQTCYGISDRVIASIIAIHGDEKG------------LILPPIVAPIQVVIVPLIFKGKEVMEKAKEIYEKLKGK----FRVHIDDRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQVDETQLMEVVEKTLNNIME. 384
17 -25.0005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model follow..  11  47....................................................................................................PWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHR-DLPLKINQWTSIVRWEFKHPTP---FIRTREFLWQEGHTASTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEG---PEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEY--AHQTSWGLTTRAIGVMIMTHGDNKG------------LVLPPKVAPVQVIIIPITVITEEQKKICNEVECILKKAGVRVKID--DRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQN. 400
18 -24.7002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  10  11.......................................RGSHMRLSRFFLPILKENPKEAEIVSHRLMLRA--------------GMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLAD--RIADRHKRELLYGPTNEEMITEIFRAYIKSYK-SLPLNLYHIQWKFRDEQRPR---FGVMRGREFLMKDAYSFDVDEAARKSYNKMFVAYLRTFARMGLKAIPMRA-ETGPIGGDLSHEFIVLAETGESGVRGIEVGQIFYFGTKYSDSMKANVTGPDGTDAPIHGGSYGVGVSRLLGAIIEACHDDNG-------------IIWPEAVAPFRVTILNLKQGDAATDAACDQLYRELSAKGVDVL---YDDTDQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGARENLALADVVARLT......... 452
19 -23.6003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model follow..  10  1.......................................................MAMGGDVTFSLTKTRDTFADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVCFWVEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYK-DLPLKIHQTCTIFRHETKNTKP---LIRVREIHWNEAHCCATAEDAVSQLSDYWKVIDTIFSDELCFKGQKLRRVCWDRFPGADYSEVSD----MPCGRVLQTAGIHNLGQRFSSTFDILYANKANESVHPYLT--CAGISTRVLACALSIHGDSGG------------LVLPPLIAPIHVVIIPIGCGKKNNQESDQQVLGKVNESKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDVGKDQKIPITEVMKVSSHTTENHEL. 405
20 -23.2005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  1..................................................................GAMGIAAKREENFSAWYIDVITKAEMIEYYDVSGPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSTRAGDTELEQPVAVRPTSETVMYPYYAKWIRSHR-DLPVRLNMWNNVIRWEFSHPTP---FIRTREFLWQEGHCAAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVET---EAVGRGCQGATSHNLGQNFGKMFDIRFQDPENNEQTLIPWQNSWGLSTRVIGVMIMVHGDNRG------------MVMPPRVASTQVIIIPVEEARQELLASCWRLESELCEGGVRARCD--LRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLED... 397
21 -23.0001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  13  18.............................................................................YLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWR-DLPQLLNQWGNVVRWEMRTR-----FLRTSEFLWQEGHTAATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEA----KDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVH--TTSWGLSWRFIGAIIMTHGDDRG------------LVLPPRLAPIQVVIVPIDESRERVLEAAQGLRQALLAQGLRVHLD--DRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGG-KETLPLAALPEALPGKLDAFHE. 390
22 -21.6002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  11  1...........................................MKQSKMLIPTLREVPNDAEVLSHQILL----RAGYI----------RQVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLYGPNLYRLKDRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRS---RSGLLRGREFIMKDGYSFADEASLDQSYRDYEKAYSRIFERCGL-EFRAIIGDGGAMGGKDSKEFMAISEIGEDTITESDYAANLEMATSLYTPKKSHETQLDLEKIATGVLAFTKGIEIGHIFKLGTRYSDAMGATVLDENGREKSVIMPTGIAPFDLHVVQMNVKDEYQTKLSQEVEAMMTEAGYEVL---VDDRNERAGVKFADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEMLEVRKEELESTLSILMNTTSE. 570
23 -20.2005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  14  3...........................................MRTSQYLLSTLKETPADAVVISHQLLL----RAGMI----------RRLASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQYGPELLRLKDRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRP---RFGLMRGREFIMKDAYSFLSQDSLQQTYDGMYQAYSKIFSRLGL-DFRPVQADNGSIGGSGSHEFHVLANSGEDDIDSSDYAANIEKAEAVPRESARGSATEDMRLVDTGTLVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMPSALAPFQIALVPLKYETESVKQATDKLYAELTAAGFEVLLD---DKKTSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLSR.... 573
24 -19.0002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  19  78.......................................................................................................................................................................................................................................................................................................................................................................QKKLLEERLKLVSELQDAGIKA--ELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPLSI 169
25 -18.7001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  13  187...................PSTAKIKEFK--LLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVD-PPMQLDETESMVLRPMNCPHHMMIYANKPHSYR-ELPIRIAELGTMHRYEASGA---SGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADESTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVTMER-FVAFLTEETK-----------------AFPTWLAPKQVQIIPVNVDLHY--DYARQLQDELKSQGVRV---SIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKK.. 643
26 -18.4004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  13  1....................................................................MGSSSSGDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWR-ELPLRLADFGVLHRNELSGA---TGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGTRPEKFLGDIEVWDQAEKQLE-EFGEKWELNSGDGAFYGPKIDIQIKDAIGRYTYVSHDGDDKKRPVIVHRAISVER-MIAILTENYG-----------------KWPFWLSPRQVMVVPV---GPTCDEYAQKVRQQFHDAKFMA--DIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRS.. 402
27 -17.8004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model follow..  13  1........................................................................MARDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWR-ELPLRLADFGVLHRNELSGA---TGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGTRPEKFLGDIEVWDQAEKQLE-EFGEKWELNSGDGAFYGPKIDIQIKDAIGRYTYVSHDGDDKKRPVIVHRAISVER-MIAILTENYG-----------------KWPFWLSPRQVMVVPV---GPTCDEYAQKVRQQFHDAKFMA--DIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRS.. 398
28 -17.3003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model follow..  65.RRGYYVVETPIIASTELFKVSGHIEFYRNNMYL---------------------------------------------------------------------------------------------------------FDIEGHEFAVKPMNCPYHILLFLNEVAKHRSPLPFKVFEFGRVHRYEPSGS---YGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKSKEEWEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFINLPRRFRLYDVVREEFGIEEVYIIHRALSIER-FLGVYLEHRR-----------------RMPFTLAPIQFAVIAVKTGGREIEDLASSIAKGLLDKGFRV--AVKGSSKTGLSSDVRHIESTAKPANVFIGAKEVREKVLDVRVFDLESMKRRRLAIAYGDAADAVENLA.. 443
29 -17.0004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model follow..  13  1........................................................................MARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYR-DLPLRMAEFGSCHRNEPSGS---HGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGS---------------DEMWDRAEADLAVALEENNIPFEYQLGEGAFYPKILYDCLDRAWQCGTVQLD--SRLSASYVGEDNERKVPVMIHRALAPVQVVIMNI---TDSQSEYVNELTQKLSNAGIRV---KADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRS.. 397
30 -16.3001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  12  188...................PNMRFCHHFK--LMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYR-DLPLRMAEFGSCHRNEPSGS---HGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSEADLAVALEENNIPFEYQLGYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAISMER-FIGILTEEFA-----------------FFPTWLAPVQVVIMNI---TDSQSEYVNELTQKLSNAGIRV---KADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRS.. 636
31 -14.9003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model follow..  75.KFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVET------------------------------------------------------------------------------------------------------TDEEKEEYGLKPMNCPGHCLIFGKKDRSYN-ELPLRFSDFSPLHRNEASGA---SGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPDLKVWNHAEQVLKEILEESGKPWKLNPGTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATSIER-FMALLIDSNE-----------------RWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKPLNDWHFNV---DLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFKLTMSQIWEKFIELEKNYK.. 454
32 -14.6001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  13  8...........................................................................................................................................................................................................................................................................................................................................................PVDCSVIVV---NKQTKDYAESVGRKVRDLGMVV--LIFLNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTPQENMPQADAMVLVARNYERYKN. 110
33 -13.0001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  15  36...........................................................................................................KEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQK-------RYRQFNQFGVEAIGAENPSVD--AEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYDCQSRLHTDPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYTEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLRLLLALEEEGIELDIEENLDDQADRYAVKLLNHLRHNGIKA---DKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK........ 420
34 -11.6001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  27.................................................................FKTAEEAAEAFGFRRIDFPSLEYLDLYR------IKSGEELLQQTYS---------------------------VDKGGREVTLIPEATPSTV---RMVTSRKDLQRPLRWYSFPKVWRYEEPQA-------RYREHYQFNADIFGSDSPEAD--AEVIALASSILDRLGLQDI--IIDRYHKISREEFVDQLRSAGIGEDGVSMIADLCSGGIDEMARITGKSSEEIARMAAVEDLLVRYDFSIVRGLTGIVFEAYDRSGQFRAILGGGR-LLLKRENVQIPREKKSVYICRVGKINSSIMNEYSRKLRERGMNV---TVEIMERGLSAQLKYASAIGADFAVIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHLISQATLE... 428
35 -11.5005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  27.................................................................EQHLASLMDAYGYQQIRLPIVEQTGLFKR---AIGDATDIVEKEMYT-------------------------FDKGNPPESLTLRPEGTAGCVRAL--VEHNLLRGATPRVWYMGPMFRYEKPQK-------RYRQFHQFGVETFLNTLGETDERTEYRNALVAFLNQRRLTTNPLRILDSKIESTQKILE----------NAPKLHDFLKEDSLSHFQQLQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRGMERLLLLLEQVQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAA-IRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK.... 432
36 -11.0004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  18  330......................................................................................................................................................................................................................................................................................................PKGRKVPCV---SIGVERIFSIV----------------EQRLEALEEKIRTTETQVLVASA---QKKLLEERLKLVSELWDAGIKA--ELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQP... 463
37 -10.9004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  18  383......................................................................................................................................................................................................................................................................................................PKGRKVPCV---SIGVERIFSIV----------------EQRLEALEEKIRTTETQVLVASA---QKKLLEERLKLVSELWDAGIKA--ELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQP... 516
38 -10.8003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  44.................................................................FDVFHATAKTFGFEEYDAPVLESEELYI------RKAGEEITEQMFN---------------------------ITKGGHRVALRPEMTPSLARLL--LGKGRSLLLPAKWYSIPQCWRYEAITR-------RRREHYQWNMDIVGVKSVSAE--VELVCAACWAMRSLGLSSKDVGIKIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFYGDWVLFDASVVGIVFEGFDREGKFRALCGGGRYDNLVIVELLQEKRLLPDIPHVVDESMRPHALAVLRRLRDAGRSA---DIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKEEGGAERGFAVPL........ 446
39 -10.6003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  10  89...........................................................................................................................................GDTGSEARALKFDQTVPLAAYI--ARHLNDLTFPFARYQMDVVFRGERAKD-------RFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIGDFVIRINNLEKIGEAKVKLELEKEGINPEQTQKIIDGSVDDVLDKLKHLSQTLPESEQFNLGVSELFCIDLAIARGLNYYTGTVYETTLIGHEALGGLTRLISRLLKA-TPAQVVVVNM---QDELMPTYLKVSQQLRQAGLNV---ITNFEKRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRLT..... 465
40 -10.3003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  44.................................................................FDVFHSTARKFGFEEYDSPVLESEELYI------RKAGEEITEQMFN---------------------------ITKGGHRVALRPEMTPSLARQL--LAKGRSLLLPAKWYSIPQCWRYEAITR-------RRREHYQWNMDIIGVKSVSSE--VELVCAACTAMQSLGLSSKDVGVKKMEKLPREEVVAQLAAIGLESNVVDAITSTLSLTIDEIAQRIGEEHEAVRELRDFITQIFGDWVIFDASVVGIVFEGFDRDGNFRALCGGGRYDNL--PTAVPCVGFGFDLVIPFDETMRPHALSILRRLRDAGRSA---DIVFDKKKVVQAFNYADRIGALRAVLVAPDEWARGEVRVKMLREGAGREEGANERGIVLPV........ 446
41 -10.3004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  12  39...........................................................................................................LELVTPIFEETQVFEKGVGAATDIVRKEMFTFQDRGGRSLTLRPEGTAAMVRAYLE--GMKVWPQPVRLWMAGPMFRAERPQK-------RYRQFHQVNYEALGSENPILD--AEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNLDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVERHLERLSVPYELEPALGLDRTAFEVHHEEIGAQSALGGGGRGVERVALALEAE-KGPDLYLIPL---TEEAVAEAFYLAEALRPR----LRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG..... 423
42 -10.1004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  47.................................................................EATVKSLLRAYGYQNIRTPIVEHTPLFTR---GIGEVTDIVEKEMYS--------------------------VDALNGENLTLRPENTAAVVRAA--IEHNMLYDGPKRLWYIGPMFRHERPQR-------RYRQFHQVGVEALGFAGPDAD--AEIVMMCQRLWEDLGLTGIKLEINSLGLAEERAAHRVELI-----RNAPKLIDFLGDVSRAHFEGLQRLLKANNVPFTINPRLVRGLDYYNLTVFEWVTDKLGAQGTVAAGGRGIERILELLKEEVPEQEGVDVYVVHQGDAAREQAFIVAERLRDTGLDVILHCSADAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPGEKSVQQSVPVESLTEFLINAMVATAE. 457
43 -9.6502el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  10  46...........................................................................................................SEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAG--IEHGLLYNQEQRLWYIGPMFRHERPQK-------RYRQFHQLGCEVFLNSIGSLEARANYRDALVAFLEKRRMYTNPLRVLDSKNPEVQALLNAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRRATPAV---AMGLERLVLLV-----QAVNPEFKADPVVDIYLVAS-----------------GADTQSAAMALAERLRDELPGV-KLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG..... 431
44 -9.5403qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  10  184......................................................................................................GVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVMAKTAGEDEKYLIATSEQPISAYHAGEWFESPAEQLPVRYAGYSSCFRREAGSGKDAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQSLGLPYRVVGISGELNNAAAKKYDLEAWFPFQQEYKELVSCSNCTDYQSRNLEIRCGIKQQNQQEKKYVHCLNSTLSATERTICCILENYQKEDG------------LVIPEVLRKY-------IPGEPEFIPYIKELPKNTTSVKKAK-------------------------------GKNPKNTTSVKKAKGKNGSR..................... 479

FFAS is supported by the NIH grant R01-GM087218-01
1 2 7 7 6 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.