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Query: 3ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMASATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYKLast
1 -140.0003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model  100  1MGSSSSGLVPRGSHMASATKNASSATPATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKFKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVETTDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKGGSGAESNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTALQKKLRNELEADDMEPVPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSFEKLTMSQIWEKFIELEKNYK 454
2 -121.0001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  32  207.GDSNNKMLQRIYGTAFFDKKELEERKERDHRKIGKELELFTNQLVGAGLPLWLPNGATIRREIERYIVDKEV-SMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQ-LDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSF-----RLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDHYDYARQLQD-----------------ELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQ-DQETVEKDEFIWNLVDEIRLKK 643
3 -118.0004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model follow..  37  2...........................ARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLK-EYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT---SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKI---------VVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQ-----------------KLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGK-DLGSMDVNEVIEKLQQEIRSRS 397
4 -118.0004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  44  1......................MGSSSSGDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYR-KRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSF---EVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGF----------SFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQ-----------------QFHDAKFMADIDDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNK-VHGERTISETIERLQQLKEFRS 402
5 -116.0004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model follow..  45  2...........................ARDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYR-KRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSF---EVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGF----------SFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQ-----------------QFHDAKFMADIDDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNK-VHGERTISETIERLQQLKEFRS 398
6 -115.0001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  35  208.GDSNNKMLQRIYGTAWADKKALEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLK-EYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT---SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKI---------VVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQ-----------------KLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGK-DLGSMDVNEVIEKLQQEIRSRS 636
7 -115.0003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model follow..  26  1..............MASGQDKTHDITVKPDSRVPVFNREFATF--TGAGVPLFSLGGGPIRYALAEVLAKFHA-RRGYYVVETPIIASTELFKVSGHIEFYRNNMYLF---DIEGHEFAVKPMNCPYHILLFLNEVASKLPLPFKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKLGVSSETFKVRLSMSKSLIGKEFMGSKEEWEGAEEALREAASRINEKYGIDEGEAAFYGPKLDFIEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTGGEVDREIE-----------DLASSIAKGLLDKGFRVAVKGSSKGLSSDVRHIESTAKPAVVFIGAKEVREKVLDVRVFDLE-SMKRRRLAIAYGDAADAVENLA 443
8 -74.3002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  16  13....SHMRLSRFFLPIL--KENPKEAEIVSHRLMLR---AGMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQN-RAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIA--DRHKRELLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPR-FGVMRGREFLMKDAYSFDVDEAGARKYNKMFVAYLRTFARMGLKAI---------PMRAETGPIGGDLSHEFIVLAETGESGVYIDRDVLNLPVPDENVDYDGDLESEVPEANRLNTRGIEVGQIFYFGTKYKANVTGPDGT-DAPIHGGSYGVGVSRLLGAIIEACHDDNWPEAVAPFRVTILNLKQGDAATDAACDQLYR--------------ELSAKGVDVLYDDTDQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGA-RENLALADVVARLT....... 452
9 -67.2004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  19  1MGSSSSGLVPRGSHMASGAGEGQEENLADWYSQVITKSEMIEYHD-ISGCYILRPWAYAIWEAIKDFFDAEIK-KLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAIPVVK---------------------------------------GRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNS-WGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCGITNALSEEDKEALIA-------KCNDYRRRLLSVNIRVRADLRNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEK-LTVAENEAETKLQAILEDIQ 426
10 -67.1005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  15  1....................GAMGIAAKREENFSAWYIDVITKAEMVSGCYIIRPWAYYVWKCVQRFLGGKIE-KLGVEDCYFPMFVSRSLEREKDHIEGFAPEVAWVTRAGDTEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHP-TPFIRTREFLWQEGHCAWKAEECAKEVLEILECYASVYEQLLAVPVVR---------------------------------------GRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENN-EQTLIPWQNSWGLSTRVIGVMIMVHGDNMPPRVASTQVIIIPVGITKDTTEEARQELLA-------SCWRLESELCEGGVRARCDLRDNSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGAR-HSVAWDAQTPAAVAALLED. 397
11 -66.3001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  16  12.GSHMQKPIKKDPNRYHGEKM--TEFSEWFHNILEE-AEIIDQRYPVKGMHVWMPHGFMIRKNTLKILRRIL--DRDHEEVLFPLLVEDELAKEAIHVKGFEDEVYWVTHLSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKHTRPLIRVREITTFKEAHIHATASEAEEQVERAVEIYKEFFNSLGIPYLITR----------RPPWDKFPGSEYTVA-------------------------------FDTLMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEYVHQTC---YGLSDRVIASVIDESGLCLPPDVAAHQVVIVPIIFKKAA------------EEVMEACRELRSRLEAAGFRVHLDDRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEK-VTADLQGIEETLRELMKDIL 410
12 -63.2003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model follow..  16  12....................TKTRDTFADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYA-KVGISQILFPTVIPESFKKESDHIKGFEAECFWVEKLQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNTK-PLIRVREIHWNEAHCCHATAEAVSQLSDYWKVIDTIFSDEL----------------------------------------CFKGQKLRRVCWDRFPGADYSEVSDVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKANESVHPYLTCAGISTRVLACALSIHGDSGGVLPPLIAPIHVVIIPIGCGKKNNQESDQQVLGKVNEIAD------TLKSKLGLRVSIDDDSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDGKDQKRVIPITEVMKVSSHTTENHE 404
13 -63.2005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model follow..  16  2....ASKENESLLGITADK----ITSFADWYSQVIVKSEMIEYYD-ISGCYILRPWSYFIWETIQSVFDQKIK-QHDVQNAYFPIFVTQKLETEKDHVEGFSPEVAWVTKSGKSAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPT-PFIRTREFLWQEGHTAHSTRKEALEMVDII--------------------------------------LNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGN---KEYAHQTSWGLTTRAIGVMIMTHGDNLPPKVAPVQVIIIPIIFKTVI-----------TEEQKKICNEVECILKKAGVRVKIDDRSNTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEK-MDIPISELESKIPKLLEEFQ 399
14 -62.6001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  18  1........MAKEKGLTPQSQDFIQKAELADYGPV-------------RGTIVVRPYGYAIWENIQQVLDRMFK-ETGHQNAYFPLFIPMSLRKEAEHVEGFSPELAVVTHAEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMR--TRPFLRTSEFLWQEGHTAHTREEAEEEVRRMLSIYARLAREYAA---------------------------------------IPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQ-AGTSHYLGENFARAFDIKFQDRDLQVK---YVHTTSWGLSWRFIGAIIDDRGLVLPPRLAPIQVVIVPIYKDESR------------ERVLEAAQGLRQALLAQGLRVHLDDDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKE--TLPLAALPEALPGKLDAFH 389
15 -61.7004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  16  4.GEGQGPKKQTRLGLEAKKEENLA----DWYSQVITKSEMIEYHD-ISGCYILRPWAYAIWEAIKDFFDAEIK-KLGVENCYFPMFVSQSALEKEKHVADFAPEVAWVTGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAIPVVK---------------------------------------GRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIP-GEKQFAYQNSWGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCGITNALSEEDKEALIA-------KCNDYRRRLLSVNIRVRADLRDNSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEK-LTVAENEAETKLQAILEDIQ 410
16 -59.3004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  17  1.......MASNILGITSKK----IENFSDWYTQVIVKSELIEYYD-ISGCYILRPAAYYIWECVQAFFNKEIK-KLNVENSYFPLFVTKNLEKEKNHIEGFSPEVAWVTKYGDSPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQP-TPFIRTREFLWQEGHTAHKNEE---EAVKLVFDILDLYRRWY-----------------------------------EEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQ---YVHQTSWGCTTRSIGIMIMTHGDDLPPNVSKYKVVIVPIFYKTTDENAIH-----------SYCKDIEKILKNAQINCVYDDRASSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEK-CNVKKESVLLETQQMLVDIH 395
17 -58.0001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  14  4.......................MLEFSEWYSDILEKAEIYDVRYPIKGCGVYLPYGFKIRRYTFEIIRNLLD-ESGHDEALFPMLIPEDLLAKEAHIKGFEDEVYWVTGKTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMTFKEAHTAHTKEEAENQVKEAISIYKKFFDTLGIPYLISKR-----------------------------------------PEWDKFPGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAYQCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGKE-------------DIVMEKAKEIYEKLKGKFRVHIDDRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEK-FQVDETQLMEVVEKTLNNIM 383
18 -55.4001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  10  1..................AASSLDELVA---KRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNYERDDMEGLDASVLTHRLVLHYSGHEATFADPMVDNAKRGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPR-NFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRE-------NLVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPEGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKA--------------RLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQI-RLHVDELEGFLRERLR... 441
19 -54.6005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  16  5..................TAKKDENFSEWYTQAIVRS---MIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIK-KMGVENSYFPMFVSRHLEKEKDHVEGFSPEVAWVTHYGDSPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQP-TPFLRTREFLWQEGHTAHATEEEAWELVLDI--------------------------------------LELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKR---LVHQTSWGCTTRSLGVMIMTHGDDIPPRVASVQVVIIPILFKDEN-----------TGEILGKCRELKTMLEKADIRVRIDDRNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEA-YQISWADLAPKLLELMEGIQ 391
20 -48.4005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  16  3............MGVTAKKSTNFAD-----YTQVIVRGELVEYYD-ISGCYIIRPWAYRIWEAVQKFFDDGIK-RLGVENCYFPMFVSQALEKEKDHVEGFKPEVAWVTHYGDSEEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQP-TPFLRTREFLWQEGHTAHATEE---EAYTLVLEILELYRQWY----------EDYLAVPVIKGEKSENE--------------------------KFAGGKKTTTIEGIIPDTGRGIQAATSHLGQNFSRMFSIEFEDEKGAKQ---LVHQTSWGCTTRSLGVMIMTHGDDLPPRVVAVQAVIIPIIFKETG-----------GMEIVAKCRELERLLNAAGVRVKVDDRNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEA-RNVPWAEAASTIPAMLETMQ 392
21 -46.7003qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  13  120.QDEENNELVRTWTPENYKKAATGAPAKLSHHEVLLRLDGYDPERVGHRGYFLRNYGVFLNQALINYGLSFLS-SKGYVPLQAPVMMNKEVMAKTAQLSQFDEELYKVI--DGEDEKYLIATSEQPISAYHAGE-ESPAEQLPVRYAGYSSCFRREAGSHAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQSLGLPYRVVGIVSGELNNAAAKK------DLEAW--------------------FPFQQEY-------------KELVSCSNCTDYQSRNLEIRCGIKQQNQQEKKYVHCLNSTLSATERTICCILENYQKEDGLVIPEVLRKYIPGEPEFIPYIKELPK-----------------NTTSVKKAKGKNPKNTTSVKKAKGKNGSR................................................ 479
22 -40.6001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  83............FADPMVDNRITKKRYRLDH--LLKEQPEEVLKRLYRAMEVEEENLHALVQ-AMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPR--GGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEIT-PRNFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRE-------NLVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKA--------------RLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQI-RLHVDELEGFLRERLR... 504
23 -33.7002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  16  12...................REVPNDAEVLSHQILLRA----YIRQVAAGIYSYLPLANRVLEKLKTIMREEFE-KIDAVEMLMPALLPAELWKESGRYETYGPNLYRLK--DRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSR-SGLLRGREFIMKDGYSFADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKE-ISEIGEDTI-DVNDVKLKNFLGADFLDEATEEDARRVLG-VLAFTKGIEIGHIFKLGT-----RYSDAMGATVLDENGREKSVIM---GCYGGVSRLLSAIVEQNADEWPTGIAPFDLHVVQMNVKDEYQTKLSQEVEA--------------MMTEAGYEVLVDDRNERAGVKFADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEML-EVRKEELESTLSILMNTTS 569
24 -32.1002cim_A mol:protein length:522 SERYL-TRNA SYNTHETASE  ali model follow..  15  164.....TLLEEKIEAAQYGAKAEHEPMEHPFKEDPTQAM--WLKRGSSRGQWIHGPQSARIFRTFEKIVLEELLEPLGYREMIFPKLVTWEVWMKSGHAKGVYPEIYYVCPEKIAEPIGGMCYAQCPPFWMYVAGETLPNEEIPVKVFDRGTSHRYE-SGGIHGIERVDEFHRIEIVWIGTKEEVLKCAEELHDRYMHIFNDILDIEW----------RKARVTPWFMAQEGLLGLAEENTVGTTDYEACLPYRGPDGEWLEFQN----------------VSINGDK-YPKGFNVKLQSGD-------ELWSGCSGGLERWAAVFLAQKGLDPANWPEEFRNRVGEMPK......................................................................................................... 511
25 -32.1005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  17  1.......MAMRTSQYLLSTLKETADAVVISHQLLLRA----MIRRLASGLYTWLPMGLRVLRKVETIVREEMN-AAGALEVLMPAVQPAELWQESGRWEQYGPELLRLK--DRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPR-FGLMRGREFIMKDAYSFLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQAGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEAVPRESARGSATEDMRLVDTPTLVIKRGIEVGHIFQLGT-----KYSEAMKLSVLSEQGKPVNLIM---GCYGGVSRVVAAAIEQNHDEWPSALAPFQIALVPLKYETESVKQATDKLYA--------------ELTAAGFEVLLDDRDKKTGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQ-NLPIGELMSFITEKLSR.. 573
26 -23.4001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  10  7.................................................................................................................................................................................................................................................................................................................................................GPVDCSVIVVNKQTKDYAESVGR-----------------KVRDLGMVVDLIFLNTSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTQEHRNMPQADAMVLVARNYERY. 108
27 -23.3003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  16  1MGSSSSGLVPRGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSH--REAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTERDLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGL------------TFRVDYASDPFFGRVGQMKAVSQKQQQL--------------------KFELLIPRSEEQPTACMSFNY--HFGTTWGIQDANGE-------PAHTGCVAGMDRLAVAMFHTHGTDLSAWPAKVRDIL.............................................................................................................. 324
28 -23.1004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  17  1MGSSSSGLVPRGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSH--REAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVCGLHGTPADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGL------------TFRVDYASDPFFGRAGKMLANNQRDQQL--------------------KFELLIPRSEEQPTACMSFNY--HFGTTWGIQDANGE-------PAHTGCVAGMDRLAVAMFHTHGTDLSAW--PAKVR............................................................................................................... 321
29 -20.9002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  14  66..................DRAKMEDTLKR-RFFYDQAFAIY-----VSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLENQGKLPFAAAQIGNSFRNEIS---SGLIRVREFTMAEIEHFVDPSEKDHPKFQNVA------------DLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVG-AHYACDCWDAESKTSYGWIEIVGTFQLTKDM-INVKRFQKTLYVEEVVPNVIEPSF--GLGRIMYTVFEHT--SFPAVVAPFKCSVLPLSQN---------------QEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTTATLRDRDSMRQI-RAEISELPSIVQDLANGN. 659
30 -19.6001wle_A mol:protein length:501 Seryl-tRNA synthetase  ali model follow..  14  157VGDESQARVLHVVG-----DKPAFSFQPRGHLEIAEKLDIIRQKRSGHRSYYLRGAGALLQHGLVNFTLNKL-IHRGFTPMTVPDLLRGVVFEGCGMTPNAKPSQIYNIDPSRFEDLNLAGTAEVG--AGYFMDHSVAFRDLPIRMVCSSTCYRAETD-EPWGLYRVHHFTKVEMFGVTGPEQSSELLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRK------DIEAWMPGRGRFGEVTSASNCT----------------------------------DFQ-SRRLHIMFQTEAGELQFAHTVNATGC-AVPRLLIALLESYQQKVPPALQP................................................................................................................... 460
31 -19.5002dq0_A mol:protein length:455 Seryl-tRNA synthetase  ali model follow..  14  118.KDENDNVPIRFWGKARVWKGHLEEWKPKLHVDLLEILGGADFARSGSRFYYLLNEIVILDLALIRFALDRL-IEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIYKVEDEDLYLIPTAEHPL-----AGMHANEILDGKDLPLLYVGVSPCFRKEAGTDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVAAKK------DIEAWMPGQGKFREVVSASNCT----------------------------------DWQ-ARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEIPKVLWK................................................................................................................... 436
32 -19.4006blj_A mol:protein length:485 Serine-tRNA ligase  ali model follow..  13  156.DNEDNNGIVRMVGNPRPKVDPETGYKCLKHIDIMRKLGGLATEEGGGRGYFLLGDLVRMNLALQNYAIDFL-AKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAA---FHLEKRFDESELPIKYCGMSTCFRKEVGADTLGIFRVHQFEKIEQFVVTSPKDNKSMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAAAKK------DLEAWFPGADEGNE--------------------------------RELVSCSNCTDYQ-TRRLEVKYGKSKKQGSEVEFCHNSTLTATSRTLCCIVENYQTPVPEVLQP................................................................................................................... 467
33 -19.3003vbb_A mol:protein length:522 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  12  145ISNDEDVDNKVERI-----WGDCTVRKKYSHVDLVVMVDGFEGEKAGSRGYFLKGVLVFLEQALIQYALRTL-GSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVISDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSDTRGIFRVHQFEKIEQFVYSSPNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAASKK------DLEAWFPGSGAFRELVSCSNCT----------------------------------DYQ-ARRLRIRYGQTKKMMDKVEFVHNATMCATTRTICAILENYQTEVPEKLKEGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTDALE............................................................. 516
34 -19.2004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  11  43...................EEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFK-RHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLK--DQGGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQIGDFLVKVNDRRITICSSVDKLDKVSWEEVKNEMVKLLFEYLTLFGIDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYD-GLVGMFDPKGRKVPCVGLSIG-VERIFSIVEQR---------TETQVLVASAQKKLLEERLKL-----------------VSELWDAGIKAELLKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEV-DVRREDLVEEIKRRTGQ.. 515
35 -19.1001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  13  3............................................KIPRGTQDILPEDSKKWRYIENQLDELMT-FYNYKEIRTPIFESTDLFARGDSTDVVQKEMYTFK--DKGDRSITLRPGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQK-----RYRQFNQFGVEAIGAENPSVD--AEVLAMVMHIYQSFGLKHLKLVINSVGDQSRLHTDPMRILDCKVDRDKE-EQVKAYLDDLGIPYTEDPN---YYTHTAFELMMDNPNYDGAITTL--------RYN-GLLELLDGPSETGI---GFALSIERLLLALEEE--GIELDIEENLDLFIVTMGDQADRYAVKL-----------------LNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESE-TIELDALVEYFKK...... 420
36 -18.7004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  11  6............................................RAVRGTKDLFGKELRMHQRIVATARKVLE-AAGALELVTPIFEETQVFEKGAATDIVRKEMFTFQ--DRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQK-----RYRQFHQVNYEALGSENPILD--AEAVVLLYECLKELGLRRLKVKLSSVGDKERLELNPMRILDSKSERDQA-KEVERHLERLSVPYELEPGLDYYVRTAFEVHHEEIGAQSALGGGGRYD---------GLSELLGGPRVPGV---GFAFGVERVALALEAE--GFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALR------------------PRLRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQV-RLSREEVPGYLLQALG... 423
37 -18.6003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  11  13............................................STPSGFPEFLPSEKRLELYLLDTIRRVYE-SYGFTPIETPAVERLEVLQAKNQGDNIIYGLEPILPPNRQAEKDKSGDTGSEARALKFDQTVPLAAYIPFARYQMDVVFRGERAKD-----RFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIGDFVIRINNRKVLTGF-----QSLNISETQIKSCISIIDNLEKIGEAKVKLELEKEGINPEQTQKIIDFVKIDGSVDDVLDKLKHLSQT-ITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTGGRYEELVGTFIGEKMPGVGISIGLTRLISRLLKA-DELMPTYLKVSQQLRQAGLNVITNFEKRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQV-EVALADLAEEIKRRLT... 465
38 -18.6005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  10  33LTERSSPKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEIFLSSLLSGCHPGFGPLGVELRKNLAAWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYY---ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGRGPTLELRQVCQGLFN--------------ELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKE-MMHISKLKDFLIKYISSAK 483
39 -18.6002dq3_A mol:protein length:425 Seryl-tRNA synthetase  ali model follow..  16  117.EDEKDNVEVRRWG-----EPRKFDFEPKPHWEIGERLGILDFKRSGSRFTVIAGWGARLERALINFMLDLH-TKKGYKEICPPHLVKPEILIGTGQLPKFEEDLYKC-----ERDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGADIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTGDLGFSAAKT------DIEVWFPSQNKYREISSCSNCE----------------------------------DFQ-ARRMNTRFKDSKTGKNRFVHTLNGSGLAVGRTLAAILENYQQEVPEVLRD................................................................................................................... 415
40 -18.5003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  13  24............................................EPVQGCRDFPPETMRLRKYLFDVFHSTAR-KFGFEEYDSPVLESEELYIRK---EEITEQMFNFI--TKGGHRVALRPEMTPSLARQLLAKGRSLL-LPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIIGVKSVSSE--VELVCAACTAMQSLGLSSKDVGVKINSRKIQAGVSADKFAPVCVIVDKMEKLPREEVVAQLAAIGLESNVVDAITSTLSLDFITQIEAYGFGDWVIFDASVVRGLAY-YTGIVFEGFDRDGNFRALCGGDCVIVELLNEK--KLLPELHHVVDDLVIPFDETMRPHALSI-----------------LRRLRDAGRSADIVFDKKKVVQAFNYADRIGALRAVLVAPDEWARGEVRVKMLREGAGR-EEGANERGIVLPVD..... 447
41 -18.5003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  13  3......................MGTLEAQTQGPGSMQKNMVETEPV-QGCRDFPPEAMRCRRHLFDVFHATAK-TFGFEEYDAPVLESEELYIRK---EEITEQMFNFI--TKGGHRVALRPEMTPSLARLLLGKGRSL-LLPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIVGVKSVSAE--VELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKF-KIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEADWVLFDASVVRGLAY-YTGIVFEGFDREGKFRALCGGDCVIVELLQEK--RLLPDIPHVVDDVVIPFDESMRPHALAV-----------------LRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGK-EEGGAERGFAVPLD..... 447
42 -18.4004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  11  15............................................KTPKGTRDYSPRQMAVREKVFDVIIRCFK-RHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLK--DQGGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQIGDFLVKVNDRRIEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGL-FGIDDKISFDLSLAR--------LDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGVERIFSIVEQR---------TETQVLVASAQKKLLEERLKL-----------------VSELWDAGIKAELLKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEV-DVRREDLVEEIKRRTGQ.. 462
43 -18.3001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  11  7............................................EKIRGFRDFYPEDMDVEKFIFKTAEEAAE-AFGFRRIDFPSLEYLDLYRIK---EELLQQTYSFV--DKGGREVTLIPEATPSTVRMVTS--RKDLQRPLRWYSFPKVWRYEEPQA-----RYREHYQFNADIFGSDSPEAD--AEVIALASSILDRLGLQDYEIRINSRKIGMTSSDPFSVFSIIDRYHKISREEFVDQLRSAGIGEDGVS--------MIADLCSGTRGIDEMARITGKSSEEIARMAAVEDLLASYGVKNVRYDFSIVRGLSYYTGIVFEAYGGRYDNLASAVISLLLKRENVQIPREKKSVYICRVGKINSSIMNEYSRKLRERGMNVTVEIMERGLSAQLKYASAIGADFAVIFGERDLERGVVTIRNMYTGSQE-NVGLDSVVEHLISQATLE. 428
44 -18.2004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  14  1..............MAMGTLEAQTQGPGSMTEQKRKLEKL----TGVKGMNDILPQDAGLWEFFEATVKSLLR-AYGYQNIRTPIVEHTPLFTRGGEVTDIVEKEMYSFVDALNGENLTLRPENTAAVVRAAIEH-NMLYDGPKRLWYIGPMFRHERPQR-----RYRQFHQVGVEALGFAGPDAD--AEIVMMCQRLWEDLGLTGIKLEINSLGLQRRLYTNPLRVLDTKNPALQE-EGLQRLLKANNVPFTINPGLDYYNLTVFEWVTDKLGAQGTVAAGGRYD---------PLIEQLGGKPTAAC---GWAMGIERILELLKEE---------EGVDVYVVHQGDAAREQAFIV-----------------AERLRDTGLDVILDGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPLRGTGDQQSVPVESLTEFLINAMVATA 456
45 -17.9002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  11  47.................EGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLVTFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYY---ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGRGPTLELRQVCQGLFN--------------ELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKE-MMHISKLKDFLIKYISSAK 466
46 -17.8002el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  11  3..................................GYQDPMAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLG-SYGYSEIRLPIVEQTPLFKRA---DVVEKEMYTFE--DRNGDSLTLRPEGTAGCVRAGIEH-GLLYNQEQRLWYIGPMFRHERPQK-----RYRQFHQLGCEVFGLQGPDID--AELIMLTARWWRALGISEHHKEKLDEDCKRRMYTNPLRVLDSKNPEVQA-AGLCKLLESAGIAYTVNQGLDYYNRTVFEWVTNSLGSQGTVCAGGRYD---------GLVEQLGGRATPAV---GFAMGLERLVLLVQAV--NPEFKADPVVDIYLVASGADTQSAAMALAERLRD---------------ELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQT-AVAQDSVAAHLRTLLG... 431
47 -17.8005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  13  7............................................VAIKGFNDVLPTQTAAWRRLEQHLASLMD-AYGYQQIRLPIVEQTGLFKRADATDIVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEH-NLLRGATPRVWYMGPMFRYEKPQK-----RYRQFHQFGVETFGVATPDID--AELIMLTARLWKRMGVDHMHKDALDEDSQRRLTTNPLRILDSKIESTQK-QQLQDYLTAAGIKFVINQK---YYNKTVFEWTTTALGSQGTVCA---------RYDGLVGQLKGKADQSVPAVGFAMG-MERLLLLLEQV---------VRDCEAFLVAEPAYQSKALVL-----------------AEQLRDQLEAANSNGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQS-QVALAELVPFLIEKFTK.. 432
48 -17.7003err_A mol:protein length:536 fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus  ali model follow..  16  220VGGEEANREIKRVG-----GPPEFSFPPLDHVALMEKNGWWEPRISGSRSYALKGDLALYELALLRFAMD-FMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAI-----AETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASDFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQ------DIEVYLPSEGRYRETHSCSALL----------------------------------DWQ-ARRANLRYRDPEGRVRYAYTLNNTAL-ATPRILAMLLENHQLQVPQALIP................................................................................................................... 519
49 -17.6003lsq_A mol:protein length:484 Seryl-tRNA synthetase  ali model follow..  12  153.QDEETGNTVVRTF-----GNTTKRAKLNHVSIMERLGMMDTSKAAGGRSYVLKGGLVQLQVALVSYSLDFL-VKRGYTPFYPPFFLNRDVMGEVAQLSQFDEELYQVSGDGDKKYLIATSEMPIAA---YHRGRWFTELKEPLKYAGMSTCFRKEAGADTLGIFRVHQFDKIEQFVVCSQEESWRHLEDMITTSEEFNKSLGLPYRVVNICSGALNNAAAKK------DLEAWFPASGAFRELVSCSNCT----------------------------------DYQ-SQSVNCRYGPNLRGTAVKEYCHNGTLCAITRTMCCICENYQTEIPDVLRP................................................................................................................... 459
50 -17.5003w3s_A mol:protein length:527 Type-2 serine--tRNA ligase  ali model follow..  13  184.......................ESGPRRIRFRGDVTEEARRRGWVGRGQWIYTPPMAALFEVLRDFLLERVTRKLGFEPALFPKLIPLETMFRMRYLHGLPDGMYYVCPPKRDPEGYVLAPAQCEPFYELLRDEVVDPERLPIKLYDCGWTYRWE-GGAAKGLERVNEFQRIEHVWIAEPEEAYRIRRELLEATKRVAEELEL------------EWKVVVSDDPFYLEGRLLEDRDIELPDVPS---------------YEFEVYLPFKGERSSEEAWISVG-SFNVHGEHFVDGFNVKEKSGRTLFTGCAGLG-VTRWVVGLLAQHGFYPYEWPEPILERIDEKFGGLPEVPKTLT............................................................................................... 524
51 -17.2004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  11  20VKSHAELEGNGEHPEAPGSGEGSEALLEICQRRLSGSKQQLSDSLLSGCHPGFGPLGVELRKNLAAWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYY---ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGRGPTLELRQVCQGLFN--------------ELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKE-MMHISKLKDFLIKYISSAK 459
52 -16.9001ser_A mol:protein length:421 PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))  ali model follow..  16  129........................FSFPPLDHVALMEKNGWWEPRSGSRSYALKGDLALYELALLRFAMDFM-ARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVWAIAETDLYLTGTAEVVL-----NALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASDFQELLENAEEILRLLELPYRLVEVATGDMGPGKWRQ------DIEVYLPSEGRYRETHSCSALL----------------------------------DWQ-ARRANLRYRDPEGRVRYAYTLNNTAL-ATPRILAMLLENHQLQVPQALIP................................................................................................................... 410
53 -16.6003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  1..................................SNAMSKPFMFEKPFGMRDTLPEWYKTKKNICDQMTEEIN-LWGYDMIETPTLEYYETVGVVS--AILDQQLFKLL--DQQGNTLVLRPDMTAPIARLVASSLKD-RAYPLRLAYQSNVYRAQQNEG-----KPAEFEQLGVELIGDGTASAD--GEVIALMIAALKRAGLSEFKVAIGHVGLYEKNYVGYREHVKSLNLSTIDKSRLMNLLSLRGGRAAIEEARGLIQTEKGK-KLYEVLESYGASEYVKFDLTLVLHMSY-YTG---------VVFEGYGNRLGVPLC-LLSKFHRPAQTGFGVRIDLLVEALNGEIISNGHEQTCILFSNERRFEAIELARKKRANGEAVVLQDLAGVTDVDAMSSNYQDVIYCIGTAGRGGEDA................................. 400
54 -16.4001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  10  2LSGYAGPADGTQQPDAPEHAVAREALVDLCRRRLSGTPQQLSTAALLSGCHAFGPLGVELRKNLASWWSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSKEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNKLPFGLAQIGVCFHPVSNSNQSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYY---ETLWNLGDQELLHTYPGNVSTIQGRDGRKNVV-PCV---LSVSGDVDLGTLAYLYD----QLAENSFARKKSLQRKVLKLHPC-----------------------LAPIKVALDVGKGPTVELRQVCQGLLN--------------ELLENGISV-SETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKE-MMHISKLRDFLVKYLASAS 441
55 -16.2005c53_B mol:protein length:903 Pol gamma B  ali model follow..  374....LENGISVWPGYLETMQSSLEQLYSK-YDEMSILFTVVTETTLENGLIHLRSRDTTMKSKLKDFLIKYISSAKNVMRRACHKVCRCLLSGFGGRVDAGQPELLTERSSPPGDSAFRLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKG-PWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYDSFQLT--ENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGRGPTLELRQVCQG--------------LFNELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKE-MMHISKLKDFLIKYISSAK 901
56 -15.6002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  15  44......EQLEMGFSDALSRDRAFQGIEHQLMSQGKRHLEQLRTVKHRP-----------ALLELEEKLAKALH-QQGFVQVVTPTIITKSALAKMT-----GEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLW-DKPIRIFEIGTCYRKESQGA----QHLNEFTM--LNLTELGTPLEERHQRLEDMARWVLEAAGIREFELVTESSVVYGDTPHFLDEKWEIFDPWVGLGFGLERLLMIREGTQHVQSARSLSYGVRLNIN......................................................................................................................................................................................... 302
57 -14.9003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  2..........................................................................RSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSPGDSAFRGGLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYY---ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGRGPTLELRQVCQGLFN--------------ELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKE-MMHISKLKDFLIKYISSAK 451
58 -14.9004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  13  2......PALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFF-VDRGFLEIKSPILIPLEYIERMG-----DNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPD-PIKIFEIGPCYRKESDGK-----HLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGID......................................................................................................................................................................................................................................................... 187
59 -13.8004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  13  1......PALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFF-VDRGFLEIKSPILIPLEYIERMG-----DNDTELSKQIFRVDKNFCLRPMVAPNIFNYARKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFFQMGSGCTREN----LESIITDFLNHLGID......................................................................................................................................................................................................................................................... 186
60 -13.8004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  16  34.................NPKDEISLNSGKPFRELESELLSRRKKDLQQ---IYAEERENYLGKLEREITRFF-VDRGFLEIKSPILIPLEYIERMG-----DNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGID......................................................................................................................................................................................................................................................... 204
61 -13.6002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  10  49............................................................................................................................................................................................................................................................................................................................SKQKFVLKTPK--ALEEKIRTTETQVLVASAQKKLLEERLKL-----------------VSELQDAGIKAELLYKKNKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEV-DVRREDLVEEIKRRTGQPL 167
62 -13.3003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  16  31.................NPKDEISLNSGKPFRELESELLSRRKKDLQQ---IYAEERENYLGKLEREITRFF-VDRGFLEIKSPILIPLEYIERMG-----DNDTELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLVFWQ--------------------------------------------------MGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTLDVMHGDLELSSALVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................................. 275
63 -13.0005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  14  2..PALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQ---IYAEERENYLGKLEREITRFF-VDRGFLEIKSPILIPLEYIERMGI----DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLAFAQMGSGCTREN----LESIITDFLNHLGIDF........................................................................................................................................................................................................................................................ 188
64 -11.5002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  18  1MGSSSSGLVPRSAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESE---IYAEERENYLGKLEREITRFFV-DRGFLEIKSPILIPLEYIERMG-----DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGIDF........................................................................................................................................................................................................................................................ 205
65 -10.7004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  18  1MGSSSSGLVPRSAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESE--QIYAEERENYLGKLEREITRFFV-DRGFLEIKSPILIPLEYIERMG-----DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLSFIQMGSGCTREN----LESIITDFLNHLGIDF........................................................................................................................................................................................................................................................ 205
66 -10.6006FTT Entity 1(prereleased)  ali follow..  11  6................................................GVADVLFEDAHKQEVLRHQLTQQLI-THGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIID-QLTGRLMGIRADITPQ---ILRIDAHHGGDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD--IELIDVLFSMINSLDMSA------VLHVDLGHVTIFKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHR.................................................... 375
67 -10.6005m8h_A mol:protein length:388 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  11  6................................................GVADVLFEDAHKQEVLRHQLTQQLI-THGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIID-QLTGRLMGIRADITPQ---ILRIDAHHGGDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD--IELIDVLFSMINSLDMSA------VLHVDLGHVTIFKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHR.................................................... 375
68 -10.0003rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  10  1...................SNAMNGTRSAWGARAWEAVRGFA--DRPPGMQDGYPDFAKRRRAVETRLLSFVE-DAGYEPVTSGLFEYVDTL-LRARSPESSRDWIRLF--DGGGDAVALRPEMTPSIARMAAPRVAA-GRTPIRWCYCERVYRRTDDPASLSWAKAAESTQVGIERIGEEASVDVDM-DVLRLLHEASAAAGVRHHRIVVSHARLAFLACLTSGNYVQFRELWQLHAAKDVDLLANLLTWSPAERDAAKRSREASDRELEALLRDAVDPRAAADVRDAWRYLCAEALHDSGLASDVVTFDLALHRELDYYTGLVFEMFGGRY......................................................................................................................... 336
69 -9.8103j7y_7 mol:protein length:338 mL39  ali model follow..  12  286LQPTQPSLIRRFQGVSLPVHLRWDKLLERSRKMVTEDQSKATEECTST...................................................................................................................................................................................................................................................................................................................................................................................................................... 338
70 -9.5201z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  15  21................................................ESAEMTLNQVKSLRQIEGRLRKLFS-LKNYQEVMPPSFEYTQLYTALESNGKTFNQEKMFQFIKHEGQSITLRYDFTLP---LVRLYSQIKDSTSARYSYFGKIFRKEKRHK-----RSTENYQIGIELFGESADKSE--LEILSLALQVIEQLGLNKTVFEIGSAKFFQRLCQLADG----------STELLTELLLKKDLSGLNAFIEKNNFSKELEIFITNELSRLENLVTNTKDDVLISSFDLKEFSEKLSMIKPIIIDLGMVPKMDYYTDLMFKAYGGRYDQLLSNFQEEAFAIG-----FCCHMDTILKALERQ...................................................................................... 331

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.