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Query: 4hwo_A mol:protein length:411 Threonine--tRNA ligase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEELELast
1 -130.0004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model  100  1MARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEELE 405
2 -125.0004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model follow..  45  1MARDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGF-SFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF. 405
3 -125.0004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  44  6.SGDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGF-SFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF. 409
4 -119.0003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model follow..  29  21.KPDSRVPVFNREFATF--TGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMYLFDIEGHEFAVKPMNCPYHILLFLNEVASKLPLPFKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFKETFKVRLSMIGKEFMGSKEEWEGAEEALREAASRINEKYGIDEGEAAFYGPKLDFIEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTEIEDLASSIAKGLLDKGFRVAVKGSSKGLSSDVRHIESTAKPAVVFIGAKEVREKVLDVRVFDLESMKRRRLAIAYGDAADAVENLAAVAEE... 448
5 -118.0003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model follow..  37  28.ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPFVKFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSYKRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTAPLNDWHFNVDLDIRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRSFEKLTMSQIWEKFIELEKNYK........ 454
6 -116.0001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  41  240.ERDHRKIGKELELFTNQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR...... 645
7 -113.0001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  99  241.KRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE.. 642
8 -77.1002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  21  34.IVSHRLMLR---AGMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIDRHKRELLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPR-FGVMRGREFLMKDAYSFDVDEAGARKYNKMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHEFIVLAETGESGVYIDRDVLNLPVPDENVDYDGDLESEVPEANRLNTRGIEVGQIFYFGTKYKANVTGPDG-TDAPIHGGSYGVGVSRLLGAIIEACHDDNWPEAVAPFRVTILNLDAATDAACDQLYRELSAKGVDVLYDDTDQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGARENLALADVVARLT............... 452
9 -69.7005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  15  8.KREENFSAWYIDVITKAEMVSGCYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSLEREKDHIEGFAPEVAWVTRAEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHP-TPFIRTREFLWQEGHCAWKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEK------------------------------FAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENN-EQTLIPWQNSWGLSTRVIGVMIMVHGDNMPPRVASTQVIIIPVGQELLASCWRLESELCEGGVRARCDLRDNSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHAQMYA.. 404
10 -66.2001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  17  36.EWFHNILEE-AEIIDQRYPVKGMHVWMPHGFMIRKNTLKILRRIL-DRDHEEVLFPLLVEDELAKEAIHVKGFEDEVYWVSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKHTRPLIRVREITTFKEAHIHATASEAEEQVERAVEIYKEFFNSLGIPYLITRRPPWDKFPGSEYTVAFDT--------------------------------LMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEYVHQTC---YGLSDRVIASVIDESGLCLPPDVAAHQVVIVPIAEEVMEACRELRSRLEAAGFRVHLDDRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVTADLQGIEETLRELMKDILENLRTR.. 416
11 -65.5004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  17  41LADWYSQVITKSEMIEYHD-ISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAIPVVK------------------------------GRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEKQFAYQNS-WGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCKEALIAKCNDYRRRLLSVNIRVRADLRNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTR.. 432
12 -64.9005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model follow..  18  20FADWYSQVIVKSEMIEYYD-ISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKLETEKDHVEGFSPEVAWVTKSAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPT-PFIRTREFLWQEGHTAHSTRKEALEMVDII-----------------------------LNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGN---KEYAHQTSWGLTTRAIGVMIMTHGDNLPPKVAPVQVIIIPITEEQKKICNEVECILKKAGVRVKIDDRNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFK.. 405
13 -63.8003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model follow..  15  18FADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVIPESFKKESDHIKGFEAECFWVQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNTK-PLIRVREIHWNEAHCCHATAEAVSQLSDYWKVIDTIFSDELCFKGQKLRRVCWDRF-------------------------------PGADYSEVSDVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKANESVHPYLTCAGISTRVLACALSIHGDSGGVLPPLIAPIHVVIIPIGCGKKNNQESADTLKSKLGLRVSIDDDSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDKDQKRVIPITEVMKVSSHTTENHELVVKNVIK 412
14 -62.2001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  20  27.LADYGPV-------------RGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSLRKEAEHVEGFSPELAVVEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMR--TRPFLRTSEFLWQEGHTAHTREEAEEEVRRMLSIYARLAREYAA------------------------------IPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQ-AGTSHYLGENFARAFDIKFQDRDLQVK---YVHTTSWGLSWRFIGAIIDDRGLVLPPRLAPIQVVIVPIYERVLEAAQGLRQALLAQGLRVHLDDRQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGK-ETLPLAALPEALPGKLDAFHEELYRR.. 395
15 -62.0004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  18  25LADWYSQVITKSEMIEYHD-ISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKHVADFAPEVAWVTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEK------------------------------FAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIP-GEKQFAYQNSWGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCGEALIAKCNDYRRRLLSVNIRVRADLRDNSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTR.. 416
16 -61.1001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  15  7FSEWYSDILEKAEIYDVRYPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAKEAHIKGFEDEVYWVTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMTFKEAHTAHTKEEAENQVKEAISIYKKFFDTLGIPYLISKRPEWDK--------------------------------FPGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAYQCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGKEEKAKEIYEKLKGKFRVHIDDRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQVDETQLMEVVEKTLNNIMENIKNR.. 389
17 -61.1004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  17  17.SDWYTQVIVKSELIEYYD-ISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNLEKEKNHIEGFSPEVAWVSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQP-TPFIRTREFLWQEGHTAHKNEE---EAVKLVFDILDLYRRW-YEEYLAVPIIKGIKSEGE-------------------------KFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQ---YVHQTSWGCTTRSIGIMIMTHGDDLPPNVSKYKVVIVPIFNAIHSYCKDIEKILKNAQINCVYDDRASSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLK.. 401
18 -57.8001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  14  8LVALCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRLVLHYSGHEATFADPMVPRGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPR-NFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPEGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR........... 441
19 -57.6005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  18  14.EWYTQAIVRS---MIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHLEKEKDHVEGFSPEVAWVTHYPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQP-TPFLRTREFLWQEGHTAHATEEEAWELVLDI-----------------------------LELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKR---LVHQTSWGCTTRSLGVMIMTHGDDIPPRVASVQVVIIPITGEILGKCRELKTMLEKADIRVRIDDRNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEK.. 397
20 -52.1005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  18  13FADWYTQVIVRGELVEYYDI-SGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQALEKEKDHVEGFKPEVAWVTHYPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQP-TPFLRTREFLWQEGHTAHATEE---EAYTLVLEILELYRQW-YEDYLAVPVIKGEKSENE--------------------------KFAGGKKTTTIEGIIPDTGRGIQAATSHLGQNFSRMFSIEFEDEKGAKQ---LVHQTSWGCTTRSLGVMIMTHGDDLPPRVVAVQAVIIPIGMEIVAKCRELERLLNAAGVRVKVDDRNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNK.. 398
21 -47.9003qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  17  151.KLSHHEVLLRLDGYDPERVGHRGYFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVMAKTAQLSQFDEELYKVIDGEDEYLIATSEQPISAYHAGE-ESPAEQLPVRYAGYSSCFRREAGSHAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQSLGLPYRVVGIVSGAAAKKYDLEAW--------------------FPFQQEY-------------KELVSCSNCTDYQSRNLEIRCGIKQQNQQEKKYVHCLNSTLSATERTICCILENYQKEDGLVIPEVLRKYIPGEPEFIPYIKELPKNTTSVKKAKGKNPKNTTSVKKAKGKNGSR....................................................... 479
22 -43.9001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  14  97YRLDH--LLKEQPEEVLKRLYRAMEVEEENLHALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRPRGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEIT-PRNFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLENLVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR........... 504
23 -35.8002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  19  22...SHQILLRA----YIRQVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNLYRLDRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSR-SGLLRGREFIMKDGYSFADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKEFMAISEIGEDTICYSTESDYAANLEMAGSIGPVLAFTKGIEIGHIFKLGT-----RYSDAMGATVLDENGREKSVIM---GCYGGVSRLLSAIVEQNADEWPTGIAPFDLHVVQMNEYQTKLSQEVEAMMTEAGYEVLVDDRNERAGVKFADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEVE..... 572
24 -33.6005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  20  24...SHQLLLRA----MIRRLASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLKDHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPR-FGLMRGREFIMKDAYSFLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQADNGSIGGSGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEAVKGTLVIKRGIEVGHIFQLGT-----KYSEAMKLSVLSEQGKPVNLIM---GCYGGVSRVVAAAIEQNHDEWPSALAPFQIALVPLTESVKQATDKLYAELTAAGFEVLLDDRDKKTGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLSR.......... 573
25 -30.8002cim_A mol:protein length:522 SERYL-TRNA SYNTHETASE  ali model follow..  14  208..............WLKRGSSRGQWIHGPQSARIFRTFEKIVLEELEPLGYREMIFPKLVTWEVWMKSGHAKGVYPEIYYVKIAEPIGGMCYAQCPPFWMYVAGETLPNEEIPVKVFDRGTSHRYE-SGGIHGIERVDEFHRIEIVWIGTKEEVLKCAEELHDRYMHIFNDILDIEW-RKARVTPWFMAQEGLLGLAEENTVGTTDYEACLPYRGPDGEWLEFQN----------------VSINGDK-YPKGFNVKLQSGD-------ELWSGCSGGLERWAAVFLAQKGLDPANWPEEFRNRVGEMPK............................................................................................... 511
26 -26.7001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  12  7..........................................................................................................................................................................................................................................................................................................GPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLIFLNTSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTEHRNMPQADAMVLVARNYERYKNECREK.. 115
27 -23.5003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  13  16.....................SGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKG--PNRQAEKDKSGDTGSEARALKFDQTVPLAAYIARHLNDLTFPFARYQMDVVFRGERAKD-----RFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIGDFVIRINNRK-QSLNISETQIKSCISIIDNLEKIGEAKVKLELEKEGINPEQTQKIIDFVKIDGSVDDVLDKLKHLSQT-ITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTGGRYEELVTPAQVVVVNMQDELMPTYLKVSQQLRQAGLNVITNFEKRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRLT........... 465
28 -23.0003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  14  27.....................QGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSL-LLPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIVGVKSVSAE--VELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEADWVLFDASVVRGLAY-YTGIVFEGFDREGKFRALCGGDCVIVELLQEK--RLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILDKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKEEGGAERGFAVPLD............. 447
29 -22.9004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  13  68..................KTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLKDQGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQIGDFLVKVNDRDSKFRTICSSVDKLDKLLFEYLTLFGIDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYD-GLVGMFDPKGRKVPCVGLSIG-VERIFSIVEQR---------TETQVLVASAQKKLLEERLKLVSELWDAGIKAELLKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ.......... 515
30 -22.8001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  16  6.....................RGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGDSTDVVQKEMYTFKDKDRSITLRPGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQK-----RYRQFNQFGVEAIGAENPSVD--AEVLAMVMHIYQSFGLKHLKLVINSVDCKVDRDKEAIKTAPEQVKAYLDDLGIPYTEDPN---YYTHTAFELMMDNPNYDGAITTL--------RYN-GLLELLDGPSETGI---GFALSIERLLLALEEE--GIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK.............. 420
31 -22.6003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  13  27.....................QGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARQLLAKGRSLL-LPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIIGVKSVSSE--VELVCAACTAMQSLGLSSKDVGVKINSRKILQTCVIVDKMEKLPREEVVAQLAAIGLESNVVDAITSTLSLDFITQIEAYGFGDWVIFDASVVRGLAY-YTGIVFEGFDRDGNFRALCGGDCVIVELLNEK--KLLPELHHVVDDLVIPFDETMRPHALSILRRLRDAGRSADIVFDKKKVVQAFNYADRIGALRAVLVAPDEWARGEVRVKMLREGAGREEGANERGIVLPVD............. 447
32 -22.5004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  12  15..................KTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLKDQGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQIGDFLVKVNDRR-AICGVSDSKFRTICSSVDKLDKVSWEEVKNE-GEKGLAPEVADRIGDYVQQHGGVSLVELDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGVERIFSIVEQREALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ.......... 462
33 -22.3001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  16  10.....................RGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSGEELLQQTYSFVDKGGREVTLIPEATPSTVRMVTS--RKDLQRPLRWYSFPKVWRYEEPQA-----RYREHYQFNADIFGSDSPEAD--AEVIALASSILDRLGLQDYEIRINSRKVDQLRSAGIGEDGVSMIADLCSGTRGIDEMARITGKSSEEIARMAAVEDLLASYGVKNVRYDFSIVRGLSY-YTGIVFEAYDRSGQFRAILGG--RYDNLASLMSGESVP---EKKSVYICRVGKINSSIMNEYSRKLRERGMNVTVEIMERGLSAQLKYASAIGADFAVIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHLISQATLE......... 428
34 -22.2003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  13  43................HSMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVSLSPADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGL---TFRVDYASDPFFGRVGQMKAVSQKQQQL--------------------KFELLIPRSEEQPTACMSFNY--HFGTTWGIQDANGE-------PAHTGCVAGMDRLAVAMFHTHGTDLSAWPAKVRDIL.................................................................................................... 324
35 -22.0004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  13  43................HSMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVSLSPADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGL---TFRVDYASDPFFGRAGKMLANNQRDQQL--------------------KFELLIPRSEEQPTACMSFNY--HFGTTWGIQDANGE-------PAHTGCVAGMDRLAVAMFHTHGTDLSAW--PAKVR------DILGLQPHVAAGAHGEGWR............................................................................ 340
36 -21.7004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  18  9.....................RGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGAATDIVRKEMFTFQDRGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQK-----RYRQFHQVNYEALGSENPILD--AEAVVLLYECLKELGLRRLKVKLSSVGDKELGVRPMLDFLGKEVERHLERLSVPYELEPGLDYYVRTAFEVHHEEIGAQSALGGGGRYD---------GLSELLGGPRVPGV---GFAFGVERVALALEAE--GFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALRP-RLRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG........... 423
37 -21.6002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  17  91.....................SGLYDFGPVGCALKNNIIQTWRQHFQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFYLRPETAQGIFLNFKRLLENQGKLPFAAAQIGNSFRNEIS-PRSGLIRVREFTMAEIEHFVDPSE---KDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVG-AHYACDCWDAESKTSYGWIEIVGTFQLTKDM-INVKRFQKTLYVEEVVPNVIEPSF--GLGRIMYTVFEHT--SFPAVVAPFKCSVLPLNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTTATLRDRDSMRQIRAEISELPSIVQDLANGNI........ 660
38 -20.9004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  15  9QTQGPGSMTEQKRKLEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGEVTDIVEKEMYSFVDAGENLTLRPENTAAVVRAAIEH-NMLYDGPKRLWYIGPMFRHERPQR-----RYRQFHQVGVEALGFAGPDAD--AEIVMMCQRLWEDLGLTGIKLEINSLDTKNPALQEIVRNAPEGLQRLLKANNVPFTINPGLDYYNLTVFEWVTDKLGAQGTVAAGGRYD---------PLIEQLGGKPTAAC---GWAMGIERILELLKEE---------EGVDVYVVHQGDAAREQAFIVAERLRDTGLDVILDGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPGEKSVQQSVPVESLTEFLINAMVATAEDGDD... 461
39 -20.5002el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  16  3........GYQDPMAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRA---DVVEKEMYTFEDRGDSLTLRPEGTAGCVRAGIEH-GLLYNQEQRLWYIGPMFRHERPQK-----RYRQFHQLGCEVFGLQGPDID--AELIMLTARWWRALGISE-KRRMYTNPLRVLDSKNPEVQA-AGLCKLLESAGIAYTVNQGLDYYNRTVFEWVTNSLGSQGTVCAGGRYD---------GLVEQLGGRATPAV---GFAMGLERLVLLVQAV--NPEFKADPVVDIYLVASGADTQSAAMALAERLRDPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG........... 431
40 -20.4005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  15  11......................GFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRADATDIVEKEMYTFFDKGESLTLRPEGTAGCVRALVEH-NLLRGATPRVWYMGPMFRYEKPQK-----RYRQFHQFGVETFGVATPDID--AELIMLTARLWKRMGVDHMQRRLTTNPLRILDSKIESTQK-QQLQDYLTAAGIKFVINQK---YYNKTVFEWTTTALGSQGTVCA---------RYDGLVGQLKGKADQSVPAVGFAMG-MERLLLLLEQV---------VRDCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK.......... 432
41 -20.4002dq0_A mol:protein length:455 Seryl-tRNA synthetase  ali model follow..  16  160..KLHVDLLEILGGADFARSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIY--KVEDEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGDLGYVADIEAWMPGQGKFREVVSASNCT----------------------------------DWQ-ARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEIPKVLWK......................................................................................................... 436
42 -20.2003vbb_A mol:protein length:522 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  13  167.KYSHVDLVVMVDGFEGEKAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSDTRGIFRVHQFEKIEQFVYSSPNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHAADLEAWFPGSGAFRELVSCSNCT----------------------------------DYQ-ARRLRIRYGQTKKMMDKVEFVHNATMCATTRTICAILENYQTEVPEKLKELQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTD....................................................... 513
43 -20.0005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  12  95......................CHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGTLELRQVCQGLFNELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK........ 483
44 -19.6002dq3_A mol:protein length:425 Seryl-tRNA synthetase  ali model follow..  14  139..KPHWEIGERLGILDFKRSGSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLY--KCERDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGADIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTGDLGFSADIEVWFPSQNKYREISSCSNCE----------------------------------DFQ-ARRMNTRFKDSKTGKNRFVHTLNGSGLAVGRTLAAILENYQQEVPEVLRD......................................................................................................... 415
45 -19.6002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  12  78......................CHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGTLELRQVCQGLFNELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK........ 466
46 -19.4006blj_A mol:protein length:485 Serine-tRNA ligase  ali model follow..  15  183..LKHIDIMRKLGGLATEEGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGADTLGIFRVHQFEKIEQFVVTSPKDNKSMFDEMIGNSEAFYQSLGIPYRVVNIVSGALNNAADLEAWFPGADEGNE--------------------------------RELVSCSNCTDYQ-TRRLEVKYGKSKKQGSEVEFCHNSTLTATSRTLCCIVENYQTPVPEVLQP......................................................................................................... 467
47 -19.0004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  12  48ICQRRHFLSGSKQQLSDSLLSGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGTLELRQVCQGLFNELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK........ 459
48 -18.7003lsq_A mol:protein length:484 Seryl-tRNA synthetase  ali model follow..  12  174.LNHVSIMERLGMMDTSKAAGGRSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVMGEVAQLSQFDEELYQVSGDGDKKYLIATSEMPIAAYHRGRWFTELKEPLKYAGMSTCFRKEAGADTLGIFRVHQFDKIEQFVVCSQEESWRHLEDMITTSEEFNKSLGLPYRVVNICSGALNNAADLEAWFPASGAFRELVSCSNCT----------------------------------DYQ-SQSVNCRYGPNLRGTAVKEYCHNGTLCAITRTMCCICENYQTEIPDVLRP......................................................................................................... 459
49 -18.7001wle_A mol:protein length:501 Seryl-tRNA synthetase  ali model follow..  19  180..RGHLEIAEKLDIIRQKRSGHRSYYLRGAGALLQHGLVNFTLNKLIHRGFTPMTVPDLLRGVVFEGCGMTPNAKPSQIYNPSRFEDLNLAGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETDTEPWGLYRVHHFTKVEMFGVTGPEQSSELLEEFLSLQMEILTELGLHFRVLDMPTQELGLPADIEAWMPGRGRFGEVTSASNCT----------------------------------DFQ-SRRLHIMFQTEAGELQFAHTVNATGC-AVPRLLIALLESYQQKVPPALQP......................................................................................................... 460
50 -18.6003err_A mol:protein length:536 fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus  ali model follow..  14  243..LDHVALMEKNGWWEPRISGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVW--AIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASDFQELLENAEEILRLLELPYRLVEVATGDMGPGKDIEVYLPSEGRYRETHSCSALL----------------------------------DWQ-ARRANLRYRDPEGRVRYAYTLNNTAL-ATPRILAMLLENHQLQVPQALIP......................................................................................................... 519
51 -18.4003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  14  1........SNAMSKPFMFEKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVS--AILDQQLFKLDQQGNTLVLRPDMTAPIARLVASSLKD-RAYPLRLAYQSNVYRAQQNEG-----KPAEFEQLGVELIGDGTASAD--GEVIALMIAALKRAGLSEFKVAIGHVGREHVKSLNLSTIDKSRLMNLLSLRGGRAAIEEARGLIQTEKGK-KLYEVLESYGASEYVKFDLTLVLHMSY-YTGVVFEGYGNRLGVPLCSGG--RY---LLSKFHRPAQA-SNGHEQTCILFSNERRFEAIELARKKRANGEAVVLQDLAGVTDVDAMSSNYQDVIYCIGTAGRGGEDA........................................ 400
52 -18.2001ser_A mol:protein length:421 PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))  ali model follow..  13  132.PPLDHVALMEKNGWWEPRSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVW--AIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASDFQELLENAEEILRLLELPYRLVEVATGDMGPGKDIEVYLPSEGRYRETHSCSALL----------------------------------DWQ-ARRANLRYRDPEGRVRYAYTLNNTAL-ATPRILAMLLENHQLQVPQALIP......................................................................................................... 410
53 -18.0002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  15  49.....................................................................................................................................................................................................................................................................................SKQKFVLKTPK--ALEEKIRTTETQVLVASAQKKLLEERLKLVSELQDAGIKAELLYKKNKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPL........ 167
54 -17.6005c53_B mol:protein length:903 Pol gamma B  ali model follow..  12  398.KYD--EMSILFTVVTETTLENGLIHLRSRDTTMKSKLKDFLIKYISRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLPLLPGDSAFRLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYDSFQLT--ENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGTLELRQVCQGLFNELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK........ 901
55 -17.4001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  12  30LCRRRHFLSGTPQQLSTAALLSGCHAFGPLGVELRKNLASQWWSSMFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESFLENLLKTSGKLRATLLHGALEHYVNCLDLVNKLPFGLAQIGVCFHPVSNSNQSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSA----------------DCQDELGRKGSKLYYSFPWG-------------KEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSG--DVDLTLAYLYDSFQ-KLHPCLAPIKVALDVGTVELRQVCQGLLNELLENGISV-SETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASAS........ 441
56 -17.0003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  13  73CQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDAL-------------HHKPGPLLPGDSAFRGGLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKETLWNLGDHELLHMYPGNVSKLHGRDGRKNVV-PCV---LSVNGDLDRGMLAYLYD----QLTENSFTRKKNLHRKVLKLHPC-----------------------LAPIKVALDVGTLELRQVCQGLFNELLENGISVYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK........ 451
57 -16.7003w3s_A mol:protein length:527 Type-2 serine--tRNA ligase  ali model follow..  12  211....................GRGQWIYTPPMAALFEVLRDFLLERVRKLGFEPALFPKLIPLETMFRMRYLHGLPDGMYYVKLRDPGYVLAPAQCEPFYELLRDEVVDPERLPIKLYDCGWTYRWE-GGAAKGLERVNEFQRIEHVWIAEPEEAYRIRRELLEATKRVAEELEL---EWKVVVSDDPFYLEGRLLEDRDIELPDVPS---------------YEFEVYLPFKGERSSEEAWISVG-SFNVHGEHFVDGFNVKEKSGRTLFTGCAGLG-VTRWVVGLLAQHGFYPYEWPEPILERI.................................................................................................... 509
58 -16.0002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  14  78.........................LRTVKHRPALLELEEKLAKALHQQGFVQVVTPTIITKSALAKMT--GEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLW-DKPIRIFEIGTCYRKESQGA----QHLNEFTM--LNLTELGTPLEERHQRLEDMARWVLEAAGIREFELVTESSVDEKWEIFDPWVGLGFGLERLLMIREGTQHVQSARSLSYGVRLNIN............................................................................................................................................................................... 302
59 -15.1004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  16  22ISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPD-PIKIFEIGPCYRKESDGK-----HLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGID...................................................................................................................................................................................................................................... 187
60 -14.0003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  17  36ISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLVFWQ-----------------------------------------MGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVFGDTLDVMHGDLELSSALVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYY....................................................................................................................... 275
61 -14.0004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  16  21ISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMVAPNIFNYARKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFFQMGSGCTREN----LESIITDFLNHLGID...................................................................................................................................................................................................................................... 186
62 -13.9004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  17  65.........................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGID...................................................................................................................................................................................................................................... 204
63 -13.3005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  19  57..................................LGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLAFAQMGSGCTREN----LESIITDFLNHLGIDFKIVGDSCMV............................................................................................................................................................................................................................ 197
64 -12.9003rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  11  24..................DRPPGMQDGYPDFAKRRRAVETRLLSFVEDAGYEPVTSGLFEYVDTLLRARSPESSRDWIRLFDGGGDAVALRPEMTPSIARMAAPRVAA-GRTPIRWCYCERVYRRTDDPASLSWAKAAESTQVGIERIGEEASVDVDM-DVLRLLHEASAAAGVRHHRIVVSHARPRLLDALGISASLSRAFLACLTSGNYLHAAKDVDLLANLLTWSPAERDAAKRSREASDRELEALLRDAVDPEALHDSGLASDVVTFDLALHRELDYYTGLVFEMFAPGVGAPIA---------GGRYDELLAQFGAGAPAVGFAFEVERVMAVLEAQ............................................................... 366
65 -12.1001z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  13  20.....................EESAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMPPSFEYTQLYTESNGKTFNQEKMFQFKHEGQSITLRYDFTLP---LVRLYSQIKDSTSARYSYFGKIFRKEKRHK-----RSTENYQIGIELFGESADKSE--LEILSLALQVIEQLGLNKTVFEIG-SAKFFQRLCQLADGSTELLTELLLKKDLSGLNAFIEKNNFSKELEIFITNELSRLENLVTNTKDDVLISSFDLKEFSEKLSMIKPIIIDLGMVPKMDYYTDLMFKAY--------SSAANQPILSGGRYDQLLSNFQEEAFAIGFCCHMDTILKALERQ............................................................... 331
66 -12.0006FTT Entity 1(prereleased)  ali follow..  16  3...................LPDGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIQLTGRLMGIRADITPQ---ILRIDAHHGGDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD--IELIDVLFSMINSLDMSALHVDLGHVTKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDGMKSIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHR........................................................... 375
67 -12.0005m8h_A mol:protein length:388 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  16  3...................LPDGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIQLTGRLMGIRADITPQ---ILRIDAHHGGDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD--IELIDVLFSMINSLDMSALHVDLGHVTKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDGMKSIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHR........................................................... 375
68 -11.8002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  18  65.........................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGIDFKIVGDSC.............................................................................................................................................................................................................................. 212
69 -11.1004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  18  65.........................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLSFIQMGSGCTREN----LESIITDFLNHLGIDFKIVGDSCMV............................................................................................................................................................................................................................ 214
70 -9.6901usy_A mol:protein length:275 ATP PHOSPHORIBOSYLTRANSFERASE REGULATORY SUBUNIT  ali model follow..  10  3................................FLDFEKVFSFYSKATKKGFSPFFVPALEKAEEPAGNFFLDR----------KGNLFSIREDFTKT---VLNHRKRYSPDSQIKVWYADFVYRYSGS-------DLVAEYQLGLEKVPRNSLDDS--LEVLEIIVESASEFFEGPVIVEIGHTGVYEDLLKEIPKDLHEKVLNLIDTKNLFLSHMKKIDLSRVEKIIEDSIYRRSPEHLKTMDLPLSVREDLLSASSFLQEKFPTVSVEIDLTLARTIEEYCGLIFTIYGGEYTVNGEKGVGGSIFLEG............................................................................................... 272

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.