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Query: 4hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MARDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEFLELast
1 -139.0004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model  100  1MARDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEFLE 407
2 -137.0004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  99  6.SGDHRKIGRDQELYFFHELSPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSRLWMTSGHWQHYSENMFSFEVEKELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALTGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLDFLRTVYSVFGFSFKLNLSTRPEKFLGDIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGDDKKRPVIVHRAILGSVERMIAILTENYGGKWPFWLSPRQVMVVPVGPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEEF.. 409
3 -125.0004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model follow..  45  1MARDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNER-KVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKAD-LRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEEL.. 404
4 -125.0003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model follow..  31  21.KPDSRVPVFNREFATF--TGAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTELFKVSGHIEFYRNNMYLFDIEGHEFAVKPMNCPYHILLFLNEVASKLPLPFKVFEFGRVHRYEPSGSIYGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEEMKLVLERLFETFKVRLSMIGKEFMGSKEEWEGAEEALREAASRINEKYGIDEGEAAFYGPKLDFIEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREEFGIEEVYIIHRALLGSIERFLGVYLEHRRGRMPFTLAPIQFAVIAVKTEIEDLASSIAKGLLDKGFRVAVKGSSKTGLSSDVRHIESTAKPAVVFIGAKEVREKVLDVRVFDLESMKRRRLAIAYGDAADAVENLAAVAEE.... 448
5 -116.0003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model follow..  45  28.ATMTSMVSQRQDLFMTDPLSPGSMFFLPNGAKIFNKLIEFMKLQQKKFGFNEVVTPLIYKKTLWEKSGHWENYADDMFKVDEEKEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALSGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLKLIDIVYNKIFPNYFINFSTRPDHFIGDLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSY-KRPIMIHRATFGSIERFMALLIDSNEGRWPFWLNPYQAVIIPVNTKNVQQLDMCTAPLNDWHFNVDLD-IRNEPVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRSFEKLTMSQIWEKFIELEKNYK......... 454
6 -114.0001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  37  240.ERDHRKIGKELELFTNQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFELSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEH-HRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDHYDYARQLQDELKSQGVRVSID-DRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR....... 645
7 -110.0001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  44  241.KRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNER-KVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKAD-LRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE... 642
8 -77.1002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  17  34.IVSHRLMLR---AGMLRQEAAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLADLWRESGRYDAYGPEMLRIDRHKRELLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPR-FGVMRGREFLMKDAYSFDVDEAGARKYNKMFVAYLRTFARMGLKIPMRAETGPIGGDLSHEFIVLAETGESGVYIDRDVLNLPVPDENVDYDGDLESEVPEANRLNTRGIEVGQIFYFGTKYKANVTGPDGT--DAPIHGGSYGVGVSRLLGAIIEACHDDNWPEAVAPFRVTILNLDAATDAACDQLYRELSAKGVDVLYD-DTDQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGARENLALADVVARLT................ 452
9 -74.9005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  14  8.KREENFSAWYIDVITKAEMVSGCYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSLEREKDHIEGFAPEVAWVTRAEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHP-TPFIRTREFLWQEGHCAWKAEECAKEVLEILECYASVYEQLLAVPVV-----------------------------RGRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENN--EQTLIPWQNSWGLSTRVIGVMIMVHGDNMPPRVASTQVIIIPVGQELLASCWRLESELCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHA....... 400
10 -70.6004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  16  41LADWYSQVITKSEMIEYHD-ISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAIPVV-----------------------------KGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPG--EKQFAYQNSWGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASE 435
11 -70.6005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model follow..  16  20FADWYSQVIVKSEMIEYYD-ISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKLETEKDHVEGFSPEVAWVTKSAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPT-PFIRTREFLWQEGHTAHSTRKEALEMVDII----------------------------LNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKG----NKEYAHQTSWGLTTRAIGVMIMTHGDNLPPKVAPVQVIIIPITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFK... 405
12 -70.0001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  16  36.EWFHNILEE-AEIIDQRYPVKGMHVWMPHGFMIRKNTLKILRRIL-DRDHEEVLFPLLVEDELAKEAIHVKGFEDEVYWVSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKHTRPLIRVREITTFKEAHIHATASEAEEQVERAVEIYKEFFNSLGIPYLITRRPPWDKFPGSEYTVA-------------------------------FDTLMPDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEY----VHQTCYGLSDRVIASVIDESGLCLPPDVAAHQVVIVPIAEEVMEACRELRSRLEAAGFRVHLD-DRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVTADLQGIEETLRELMKDILENLRTRAWE 419
13 -67.9003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model follow..  16  18FADWFDAIMDAAELVDRRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVIPESFKKESDHIKGFEAECFWVQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNTK-PLIRVREIHWNEAHCCHATAEAVSQLSDYWKVIDTIFSDEL------------------------------CFKGQKLRRVCWDRFPGADYSEVSDVVMPCGRVLQTAGIHNLGQRFSSTFDILYANKANES-VHPYLTCAGISTRVLACALSIHGDSGGVLPPLIAPIHVVIIPIGCGKKNNQESADTLKSKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDKDQKRVIPITEVMKVSSHTTENHELVVKNVIKD 413
14 -67.7001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  20  27.LADYGPV-------------RGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSLRKEAEHVEGFSPELAVVEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMR--TRPFLRTSEFLWQEGHTAHTREEAEEEVRRMLSIYARLAREYAA-----------------------------IPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQ-AGTSHYLGENFARAFDIKFQDRDLQVK----YVHTTSWGLSWRFIGAIIDDRGLVLPPRLAPIQVVIVPIYERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGK-ETLPLAALPEALPGKLDAFHEELYRRALA 398
15 -67.2004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  17  25LADWYSQVITKSEMIEYHD-ISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKHVADFAPEVAWVTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHP-QPFLRTREFLWQEGHSAFTMEEAAEEVLQILDLYAQVYEELLAIPVV-----------------------------KGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPG--EKQFAYQNSWGLTTRTIGVMTMVHGDNLPPRVACVQVVIIPCGEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTR... 416
16 -66.9004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  17  17.SDWYTQVIVKSELIEYYD-ISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNLEKEKNHIEGFSPEVAWVSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPT-PFIRTREFLWQEGHTAHKNEE---EAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGE-------------------------KFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQ----YVHQTSWGCTTRSIGIMIMTHGDDLPPNVSKYKVVIVPIFYKTTSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLK... 401
17 -65.5001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  16  7FSEWYSDILEKAEIYDVRYPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAKEAHIKGFEDEVYWVTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMTFKEAHTAHTKEEAENQVKEAISIYKKFFDTLGIPYLISKRPEWDKF-------------------------------PGAEYTMAFDTIFPDGRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAYQTCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGKEEKAKEIYEKLKGKFRVHID-DRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQVDETQLMEVVEKTLNNIMENIKNRAWE 392
18 -62.7005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  17  14.EWYTQAIVRS---MIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHLEKEKDHVEGFSPEVAWVSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQP-TPFLRTREFLWQEGHTAHATEEEAWELVLDI----------------------------LELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKR----LVHQTSWGCTTRSLGVMIMTHGDDIPPRVASVQVVIIPITGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEK... 397
19 -58.7001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  15  8LVALCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRLVLHYSGHEATFADPMVPRGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPR-NFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLNLVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPEGKWFVPYVIEPSAGVDR-GVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVPEITEYAKRLKARLLALGLGRVLY-EDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR............ 441
20 -57.3005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  17  13FADWYTQVIVRGELVEYYDI-SGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQALEKEKDHVEGFKPEVAWVTHYPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQP-TPFLRTREFLWQEGHTAHATEE---EAYTLVLEILELYRQWYEDYLAVPVIKGEKSENE--------------------------KFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRFSIEFEDEKGAKQ----LVHQTSWGCTTRSLGVMIMTHGDDLPPRVVAVQAVIIPIIFKETGKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNK... 398
21 -49.0003qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  13  151.KLSHHEVLLRLDGYDPERVGHRGYFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKEVMAKTAQLSQFDEELYKVIDGEDEYLIATSEQPISAYHAGE-ESPAEQLPVRYAGYSSCFRREAGSHAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEFYQSLGLPYRVVGIVSGELNNAAAKKYDLEA----------------FPFQQEY-------------KELVSCSNCTDYQSRNLEIRCGIKQQNQQE-KKYVHCLNSTLSATERTICCILENYQKEDGLVIPEVLRKYIPGEPEFIPYIKELPKNTTSVKKAKGKN-PKNTTSVKKAKGKNGSR........................................................ 479
22 -44.5001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  14  97YRLDH--LLKEQPEEVLKRLYRAMEVEEENLHALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRPRGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEIT-PRNFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSLVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVPEITEYAKRLKARLLALGLGRVLY-EDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR............ 504
23 -36.7002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  18  22...SHQILLRA----YIRQVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNLYRLDRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSR-SGLLRGREFIMKDGYSFADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGASEIGEDTI-DVNDVKLKNFLGADFLDEATEEDARRVLG-VLAFTKGIEIGHIFKLGT-----RYSDAMGATVLDENGRE--KSVIMGCYGIG-VSRLLSAIVEQNADEWPTGIAPFDLHVVQMNEYQTKLSQEVEAMMTEAGYEVLVD-DRNERAGVKFADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEV....... 571
24 -34.7005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  19  24...SHQLLLRA----MIRRLASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLDRHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPR-FGLMRGREFIMKDAYSFLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQADNGSANSGEDDI-KTIKTLVVHGAEEGTLVALIVRGDHELNEIKAANQPLVAIKRGIEVGIFQLGTKYSEAMKLSVLSEQGKP--VNLIMGCYGIG-VSRVVAAAIEQNHDEWPSALAPFQIALVPLTESVKQATDKLYAELTAAGFEVLLDDRDKKSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLSR........... 573
25 -33.9002cim_A mol:protein length:522 SERYL-TRNA SYNTHETASE  ali model follow..  16  208..............WLKRGSSRGQWIHGPQSARIFRTFEKIVLEELLEPGYREMIFPKLVTWEVWMKSGHAKGVYPEIYYVKIAEPIGGMCYAQCPPFWMYVAGETLPNEEIPVKVFDRGTSHRYE-SGGIHGIERVDEFHRIEIVWIGTKEEVLKCAEELHDRYMHIFNDILDIEWRKARVTPWFMAQEGLLGLAEENTVGTTDYEACLPYRGPDGEWLEFQN----------------VSINGDK-YPKGFNVKLQSGD--------ELWSGCSGGLERWAAVFLAQKGLDPANWPEEFRNRVGEMPK................................................................................................. 511
26 -27.2001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  15  7..........................................................................................................................................................................................................................................................................................................GPVDCSVIVVNKQTKDYAESVGRKVRDLGMVVDLILNTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTEHRNMPQADAMVLVARNYERYKNECREK... 115
27 -24.1004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  15  68..................KTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLKDQGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQIGDFLICGVSDSKFRTICSSVDKLDKLLFEYLTLFGIDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCV---GLSIGVERIFSIVEQR---------TETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ........... 515
28 -23.8004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  15  15..................KTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETL--MGKYGEDSKLIYDLKDQGELLSLRYDLTVPFARYLAMN----KLTNIKRYHIAKVYRRDNPAMTRG--RYREFYQCDFDIAGNFDPMIPDA-ECLKIMCEILSSLQIGDFLICGVSDSKFRTICSSVDKLDKLLFEYLTLFGIDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGMFDPKGRKVPCV---GLSIGVERIFSIVEQR---------TETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ........... 462
29 -23.2004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  13  43................HSMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVSLSPADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDP--FFGRAGKMLANNQRDQQL--------------------KFELLIPRSEEQPTACMSFNY--HFGTTWGIQDANGE--------PAHTGCVAGMDRLAVAMFHTHGTDLSAW--PAKVR------DILGLQPHVAAGAHGEGWR.............................................................................. 340
30 -23.1003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  12  43................HSMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQLEKSGYLKSFPNLLGCVSLSPADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRREPS---KHLDRLQSFRMREYVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYASDP--FFGRVGQMKAVSQKQQQL--------------------KFELLIPRSEEQPTACMSFNY--HFGTTWGIQDANGE--------PAHTGCVAGMDRLAVAMFHTHGTDLSAWPAKVRDIL...................................................................................................... 324
31 -22.9001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  15  10.....................RGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSGEELLQQTYSFVDKGGREVTLIPEATPSTVRMVTS--RKDLQRPLRWYSFPKVWRYEEPQA-----RYREHYQFNADIFGSDSPEAD--AEVIALASSILDRLGLQDIYEIRINSRKIMEEDRYHKISREEFVDQLRSAGIG-EMARITGKSSEEIARMAAVEDLLASYGVKNVRYDFSIVR--GLSYYTGIVFEAYDRSGQFRAILGG--RYDNLASLMSGESVP---EKKSVYICRVGKINSSIMNEYSRKLRERGMNVTVEIM-ERGLSAQLKYASAIGADFAVIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHLISQATLE.......... 428
32 -22.3003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  17  27.....................QGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARQLLAKGRSLL-LPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIIGVKSVSSE--VELVCAACTAMQSLGLSVVEQAGVSADKFAPVCVIVDKMEKLPREEVVAQLAAIGLESNVVDAITSTLSLDFITQIEAYGFGDWVIFDASVVR--GLAYYTGIVFEGFDRDGNFRALCGGDCVIVELLNEK--KLLPELHHVVDDLVIPFDETMRPHALSILRRLRDAGRSADIVFD-KKKVVQAFNYADRIGALRAVLVAPDEWARGEVRVKMLREGAGREEGANERGIVLPVD.............. 447
33 -22.3005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  15  11......................GFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRADATDIVEKEMYTFFDKGESLTLRPEGTAGCVRALVEH-NLLRGATPRVWYMGPMFRYEKPQK-----RYRQFHQFGVETFGVATPDID--AELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRNA-QQLQDYLTAAGIKFVINQGLDYYNKTVFEWTTTALGSQGTVCAGGRYD---------GLVGQLKGKADQSVPAVGFAMG-MERLLLLLEQV---------VRDCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK........... 432
34 -22.2003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  16  27.....................QGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQMFNFITKGGHRVALRPEMTPSLARLLLGKGRSL-LLPAKWYSIPQCWRYEAITR-----RRREHYQWNMDIVGVKSVSAE--VELVCAACWAMRSLGLSSKDVGIKVNSRKVLQDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEADWVLFDASVVR--GLAYYTGIVFEGFDREGKFRALCGGDCVIVELLQEK--RLLPDIPHVVDDVVIPFDESMRPHALAVLRRLRDAGRSADIILD-KKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKEEGGAERGFAVPLD.............. 447
35 -22.1002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  16  91.....................SGLYDFGPVGCALKNNIIQTWRQHFQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFYLRPETAQGIFLNFKRLLENQGKLPFAAAQIGNSFRNEIS-PRSGLIRVREFTMAEIEHFVDPSE--KDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGEMAHYADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVRFQKTLYVEEVVPNVIEPSF--GLGRIMYTVFEHT--SFPAVVAPFKCSVLPLNQEFMPFVKELSEALTRHGVSHKVD-DSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTTATLRDRDSMRQIRAEISELPSIVQDLANGNI......... 660
36 -21.6001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  16  7......................GTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGDSTDVVQKEMYTFDKGDRSITLRPGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQK-----RYRQFNQFGVEAIGAENPSVD--AEVLAMVMHIYQSFGLKHLKLV-----NSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTDPGIPYTEDPNLVR--------LDYYTHTAFELMMDNPNYDGAITTLC---ELLDSIERLLLALEEE--GIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYL-QRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK............... 420
37 -21.4003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  16  16.....................SGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKLPPNRQAEKDKSGDTGSEARALKFDQTVPLAAYIARHLNDL-TFPFARYQMDVVFRGERAKD-----RFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIDFVIRINNRK-QSLNISETQIKSCISIIDNLEKIGEAKVKLELEKEGINPEQTQKIIDFVKIDGSVDDVQFNLGVSELETVITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTGGRYEELVTPAQVVVVNMQDELMPTYLKVSQQLRQAGLNVITNFE-KRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRLT............ 465
38 -21.2005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  12  72ICQRRHFLSGSKQQLSDSLLSGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMS--------PSNFSSSDCQDEEGRKGNK----YYNFPWGKELIETLWNLGDHELLHMYPGNVS------------------KLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK......... 483
39 -21.0002el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  14  3........GYQDPMAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAEVTDVVEKEMYTFDRNGDSLTLRPEGTAGCVRAGIEH-GLLYNQEQRLWYIGPMFRHERPQK-----RYRQFHQLGCEVFGLQGPDID--AELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDA-AGLCKLLESAGIAYTVNQGLDYYNRTVFEWVTNSLGSQGTVCAGGRYD-GLVEQLGGRATPAVG---------------GLERLVLLVQAV--NPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG............ 431
40 -21.0002dq3_A mol:protein length:425 Seryl-tRNA synthetase  ali model follow..  18  139..KPHWEIGERLGILDFKRSGSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEILIGTGQLPKFEEDLY--KCERDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGADIRGIIRQHQFDKVELVKIVHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTGDLGFSDIEVWFPSQNKYREISSCSNCE----------------------------------DFQ-ARRMNTRFKDSKTGKNRFVHTLNGSGL-AVGRTLAAILENYQQEVPEVLRD........................................................................................................... 415
41 -20.7004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  17  10......................GTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGAATDIVRKEMFTFDRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQK-----RYRQFHQVNYEALGSENPILD--AEAVVLLYECLKELGLRRKERLELNPMRILDSKSERDQA-KEVERHLERLSVPYELEPGLDYYVRTAFEVHHEEIGAQSALGGGGRYD-GLSELLGGPRVPGVG---------------GVERVALALEAE--GFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALRP-RLRAEYALA-PRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG............ 423
42 -20.6002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  12  78......................CHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM---------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIET------------------WNLGDHELLHMYPGNLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK......... 466
43 -20.5002dq0_A mol:protein length:455 Seryl-tRNA synthetase  ali model follow..  15  160..KLHVDLLEILGGADFARSGSRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVEEGSTSFEDFEDVIY--KVEDEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAGTDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTGD--LGDIEAWMPGQGKFREVVSASNCT----------------------------------DWQ-ARRLNIRFRDRTDEKPRYVHTLNSTAI-ATSRAIVAILENHQEEIPKVLWK........................................................................................................... 436
44 -20.4004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  15  9QTQGPGSMTEQKRKLEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGEVTDIVEKEMYSFVDAGENLTLRPENTAAVVRAAIEH-NMLYDGPKRLWYIGPMFRHERPQR-----RYRQFHQVGVEALGFAGPDAD--AEIVMMCQRLWEDLGLTGIKLEINSLGLAEERAAHRVELIKYLEQHADKLDDDAQRRLYTNPL-APKLIDFLGDVSRAHFELKANNVPFTINPRLGLDYYNLTVFEWVTDKLGAQGTVAAGGRYDP-LIEQLGGK-----EGVDVYVVHQGDAAREQAFIVAERLRDTGLDVILHCSADASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPGEKSVQQSVPVESLTEFLINAMVATAEDGDD.... 461
45 -20.0004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  12  48ICQRRHFLSGSKQQLSDSLLSGCHPGFGPLGVELRKNLAAEWWTSVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAM---------------SPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIET------------------WNLGDHELLHMYPGNLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK......... 459
46 -19.9003vbb_A mol:protein length:522 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  12  167.KYSHVDLVVMVDGFEGEKAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKVDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVGSDTRGIFRVHQFEKIEQFVYSSPNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSGSLNHADLEAWFPGSGAFRELVSCSNCT----------------------------------DYQ-ARRLRIRYGQTKKMMDKVE-FVHNATMCATTRTICAILENYQTEVPEKLKEGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDVTLENRLQNMEVTD........................................................ 513
47 -19.9002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  14  49.....................................................................................................................................................................................................................................................................................SKQKFVLKTPK--ALEEKIRTTETQVLVASAQKKLLEERLKLVSELQDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQPL......... 167
48 -19.1001ser_A mol:protein length:421 PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))  ali model follow..  17  132.PPLDHVALMEKNGWWEPRSGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVW--AIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASDFQELLENAEEILRLLELPYRLVEVATGDMGPGDIEVYLPSEGRYRETHSCSALL----------------------------------DWQ-ARRANLRYRDPEGRVRYAYTLNNTAL--ATPRILAMLLENHQLQVPQALIP........................................................................................................... 410
49 -18.9003lsq_A mol:protein length:484 Seryl-tRNA synthetase  ali model follow..  14  174.LNHVSIMERLGMMDTSKAAGGRSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVMGEVAQLSQFDEELYQVSGDGDKKYLIATSEMPIAAYHRGRWFTELKEPLKYAGMSTCFRKEAGADTLGIFRVHQFDKIEQFVVCSQEESWRHLEDMITTSEEFNKSLGLPYRVVNICSGA--LNDLEAWFPASGAFRELVSCSNCT----------------------------------DYQ-SQSVNCRYGPNLRGTANVKEYCHNGTLCAITRTMCCICENYQTEIPDVLRP........................................................................................................... 459
50 -18.9001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  13  30LCRRRHFLSGTPQQLSTAALLSGCHAFGPLGVELRKNLASQWWSSMFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSLRATLLHGALEHYVNCLDLVNKLPFGLAQIGVCFHPVSNSNQSSVTRVGEKTEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMS--------PSNFSSADCQDELGRKGSK----YYSFPWGKEPIETLWNLGDQELLHTYPGNVS------------------TIQGRDGRKNVVPCVLSVSG--DVDLTLAYLYDSFQ-KLHPCLAPIKVALDVGTVELRQVCQGLLNELLENGISVGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASAS......... 441
51 -18.9003err_A mol:protein length:536 fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus  ali model follow..  18  243..LDHVALMEKNGWWEPRISGSRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAFLGTGHFPAYRDQVW--AIAETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAGSDVRGLMRVHQFHKVEQYVLTEASLEASDFQELLENAEEILRLLELPYRLVEVATGD--MGDIEVYLPSEGRYRETHSCSALL----------------------------------DWQ-ARRANLRYRDPEGRVRYAYTLNNTAL--ATPRILAMLLENHQLQVPQALIP........................................................................................................... 519
52 -18.7006blj_A mol:protein length:485 Serine-tRNA ligase  ali model follow..  15  183..LKHIDIMRKLGGLATEEGGGRGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQMKKVAQLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGADTLGIFRVHQFEKIEQFVVTSPKDNKSMFDEMIGNSEAFYQSLGIPYRVVNIVSGA---------------------------------NNAAAKKFDLEAADEGNEYRELVSCSTDYQ-TRRLEVKYGKSKKQGSEVE-FCHNSTLTATSRTLCCIVENYQTPVPEVLQP........................................................................................................... 467
53 -18.6003w3s_A mol:protein length:527 Type-2 serine--tRNA ligase  ali model follow..  16  211....................GRGQWIYTPPMAALFEVLRDFLLERVRKLGFEPALFPKLIPLETMFRMRYLHGLPDGMYYVKLRDPGYVLAPAQCEPFYELLRDEVVDPERLPIKLYDCGWTYRWE-GGAAKGLERVNEFQRIEHVWIAEPEEAYRIRRELLEATKRVAEELELEWKVVVSDDP--FYLEGRLLEDRDIELPDVP-------------------SYEFEVYLPFKGERSSEEAWISVGSFNVHGEHFVDGFNVKEKSGRTLFTGCAGGVTRWVVGLLAQHGFYPYEWPEPILERI...................................................................................................... 509
54 -18.4001wle_A mol:protein length:501 Seryl-tRNA synthetase  ali model follow..  19  180..RGHLEIAEKLDIIRQKRSGHRSYYLRGAGALLQHGLVNFTLNKLIHRGFTPMTVPDLLRGVVFEGCGMTPNAKPSQIYNPSRFEDLNLAGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETDTEPWGLYRVHHFTKVEMFGVTGPEQSSELLEEFLSLQMEILTELGLHFRVLDMPTQE--LGDIEAWMPGRGRFGEVTSASNCT----------------------------------DFQ-SRRLHIMFQTEAGELQFAHTVNATGC--AVPRLLIALLESYQQKVPPALQP........................................................................................................... 460
55 -17.9003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  13  73CQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDAL-------------HHKPGPLLPGDSAFRGGLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTK-NGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFA--------MSPSNFSSSDCQDEEGRKGNK----YYNFPWGKELIETLWNLGDHELLHMYPGNVS------------------KLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK......... 451
56 -17.3005c53_B mol:protein length:903 Pol gamma B  ali model follow..  13  101............................PLGVELRKNLAAEWWTVVFREQVFPVDALHHKPGPLLPGDSAFRKLRENLLHGALEHYVNCLDLVN---------------KRLPYGLAQIGVCFHPVFDTKQNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFA--------MSPSNFSSSDCQDEEGRKGNK----YYNFPWGKELIETLWNLGDHELL------------------HMYPGNVSKLHGRDGRKNVVPCVLSVNG--DLDRMLAYLYDSFQ-KLHPCLAPIKVALDVGRGPTLELCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNVMRSR... 456
57 -17.1003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  11  1........SNAMSKPFMFEKPFGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVS--AILDQQLFKLDQQGNTLVLRPDMTAPIARLVASSLKD-RAYPLRLAYQSNVYRAQQNEG-----KPAEFEQLGVELIGDGTASADEVIALMIAALKRAGLSEFKVAIGHVGYVNALLMDVVGNEQRADRLRRFLYEKNYVGYREHVKSLNLSTIDKSRLMAAIEEARGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVLHMSYYTGVVFEGYGGRYDELLSGHEQTCILFSNERRFEAIELARKKRANGEAVVLQDL-AGVTDVDAMSSNYQDVIYCIGTAGRGGEDA......................................... 400
58 -16.2004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  16  22ISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGIDFKIVGDSC................................................................................................................................................................................................................................ 195
59 -15.6002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  18  78.........................LRTVKHRPALLELEEKLAKALHQQGFVQVVTPTIITKSALAKMT--GEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLW-DKPIRIFEIGTCYRKESQGA----QHLNEFTM--LNLTELGTPLEERHQRLEDMARWVLEAAGIREFELVTESSVVYGDTVDVMKGDLELLERLLMIREGTQHVQSARSLSYGVRLNIN.................................................................................................................................................................................. 302
60 -15.2004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  16  21ISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMVAPNIFNYARKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFFQMGSGCTREN----LESIITDFLNHLGIDFKIVGDS................................................................................................................................................................................................................................. 193
61 -15.0004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  16  65.........................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGIDFKIVGDSC................................................................................................................................................................................................................................ 212
62 -14.6003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  16  36ISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLVFWQMGSGCTREN----LESIITDFLNHLGIDFKIVGDSC................................................................................................................................................................................................................................ 209
63 -14.5005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  18  57..................................LGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLAFAQMGSGCTREN----LESIITDFLNHLGIDFKIVGDS................................................................................................................................................................................................................................. 194
64 -12.7002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  17  65.........................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLNFCQMGSGCTREN----LESIITDFLNHLGIDFKIVGDS................................................................................................................................................................................................................................. 211
65 -12.6006FTT Entity 1(prereleased)  ali follow..  14  3...................LPDGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIQLTGRLMGIRADITPQ---ILRIDAHHGGDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD--IELIDVLFSMINSLDMSAVLHVDLGHKRLAELAALSASDTEQLMQLYANKNLP-VLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDGMKSIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDGLTHRLSLADNQWRLHAV................................................... 388
66 -12.6005m8h_A mol:protein length:388 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  14  3...................LPDGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESL-LSGASEDLKRQTFKIQLTGRLMGIRADITPQ---ILRIDAHHGGDGIARYCYAGDVIHTLPSGL-----GSRTPLQLGAEIFGCESIAAD--IELIDVLFSMINSLDMSAVLHVDLGHKRLAELAALSASDTEQLMQLYANKNLP-VLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYGGRFDGMKSIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDGLTHRLSLADNQWRLHAV................................................... 388
67 -12.4001z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  14  21......................ESAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMPPSFEYTQLYTESNGKTFNQEKMFQFKHEGQSITLRYDFTLP---LVRLYSQIKDSTSARYSYFGKIFRKEKRHK-----RSTENYQIGIELFGESADKSE--LEILSLALQVIEQLGLNKTVFEIGSAKFFQRLCQLADGSTELLTELLLKKDLSGLNAFIEKNNFSKELEIFITNELSRLENLVTNTKDDVLISSFDQLKEFSEKLSMIKPIIIDLGMVPKMDYYTDLMFKAY--------SSAANQPILSGGRYDQLLSNFQEEAFAIGFCCHMD.......................................................................... 322
68 -12.1004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  17  65.........................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMG--DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----EHLEEFTMLSFIQMGSGCTREN----LESIITDFLNHLGIDFKIVGDS................................................................................................................................................................................................................................. 211
69 -11.2003rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  13  24..................DRPPGMQDGYPDFAKRRRAVETRLLSFVEDAGYEPVTSGLFEYVDTLLRARSPESSRDWIRLFDGGGDAVALRPEMTPSIARMAAPRVAA-GRTPIRWCYCERVYRRTDDPASLSWAKAAESTQVGIERIGEEASVDVDM-DVLRLLHEASAAAGVRHHRIVVSH-PRLLDALGISASLSRAFLACLTSGNLTWSPAERDAAKRSREASDRELEALLRDAVRAAADVRDAWRYLCRLAEALHDSGLASDVVTFDLALHRELDYYTGLVFEMF--------APGVGAPIAQGGRYDELLAQFGAGAPAVGFAFEVE.......................................................................... 357

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.