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Query: 5f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEKDHVEGFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLSLDNEDNQSMTGAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSYLast
1 -163.0005f9y_A mol:protein length:511 Aminoacyl-tRNA synthetase  ali model  100  1MASKENESLLGITADKITSFADWYSQVIVKSEMIEYYDISGCYILRPWSYFIWETIQSVFDQKIKQHDVQNAYFPIFVTQKKLETEKDHVEGFSPEVAWVTKSGKSDLAEPIAIRPTSETIMYPYFAKWIRSHRDLPLKINQWTSIVRWEFKHPTPFIRTREFLWQEGHTAHSTRKEALEMVDIILNEYASIYEDLLATPVVKGTKSENEKFPGGDITKSIEGFIPEIGRAVQAATSHLLGQNFSKMFGVEFEDEKGNKEYAHQTSWGLTTRAIGVMIMTHGDNKGLVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRVKIDDRSNYTPGWKYNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQNRLLFKAKQRQNESIIRVDTFDKVMDTLNQKKMVIAPWCEDVSCEEEIKKETARLSLDNEDNQSMTGAMKSLCIPNDQIFKIEEGKTKCFFCDKLAKKFTLFGRSY 505
2 -156.0004ncx_A mol:protein length:506 Proline--tRNA ligase  ali model follow..  57  1....MASNILGITSKKIENFSDWYTQVIVKSELIEYYDISGCYILRPAAYYIWECVQAFFNKEIKKLNVENSYFPLFVTKNKLEKEKNHIEGFSPEVAWVTKYGDSNLPEEIAIRPTSETIMYSVFPKWIRSYRDLPLKLNQWNTVVRWEFKQPTPFIRTREFLWQEGHTAHKNEEEAVKLVFDILDLYRRWYEEYLAVPIIKGIKSEGEKFGGANFTSTAEAFISENGRAIQAATSHYLGTNFAKMFKIEFEDENEVKQYVHQTSWGCTTRSIGIMIMTHGDDKGLVLPPNVSKYKVVIVPIFYKTTDENAIHSYCKDIEKILKNAQINCVYDDRASYSPGYKFNHWELRGIPIRIEVGPKDLQNNSCVIVRRDNNEKCNVKKESVLLETQQMLVDIHKNLFLKAKKKLDDSIVQVTSFSEVMNALNKKKMVLAPWCEDIATEEEIKKETQRLSLNQTSETTLSGAMKPLCIPLDQPP--MPPNMKCFWSGKPAKRWCLFGRSY 500
3 -153.0005xif_A mol:protein length:500 Prolyl-tRNA synthetase (ProRS)  ali model follow..  62  2.........AMVTAKKDENFSEWYTQAIVRSEMIEYYDISGCYIMRPWAFHIWEKVQRFFDDEIKKMGVENSYFPMFVSRHKLEKEKDHVEGFSPEVAWVTHYGDSPLPEKIAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWCSVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAWELVLDILELYRRWYEECLAVPVIKGEKSEGEKFAGGKKTTTVEAFIPENGRGIQAATSHLLGTNFAKMFEIEFEDEEGHKRLVHQTSWGCTTRSLGVMIMTHGDDKGLVIPPRVASVQVVIIPILFKDENTGEILGKCRELKTMLEKADIRVRIDDRSNYTPGWKYNHWEVKGVPLRLELGPKDLAKGTARVVRRDTGEAYQISWADLAPKLLELMEGIQRSLFEKAKARLHEGIEKISTFDEVMPALNRKHLVLAPWCEDPESEEQIKKETQKLSEIGDSEQVMTGAMKTLCIPFDQPP--MPEGTKCFYTGKPAKRWTLWGRSY 500
4 -152.0005xip_A mol:protein length:498 Prolyl-tRNA synthetase, putative  ali model follow..  62  1.......GAMGVTAKKSTNFADWYTQVIVRGELVEYYDISGCYIIRPWAYRIWEAVQKFFDDGIKRLGVENCYFPMFVSQAKLEKEKDHVEGFKPEVAWVTHYGDSELPEKVAIRPTSETIMYPAYAKWIRSHRDLPLKLNQWNNVVRWEFKQPTPFLRTREFLWQEGHTAHATEEEAYTLVLEILELYRQWYEDYLAVPVIKGEKSENEKFAGGKKTTTIEGIIPDTGRGIQAATSHLLGQNFSRMFSIEFEDEKGAKQLVHQTSWGCTTRSLGVMIMTHGDDKGLVLPPRVVAVQAVIIPIIFKETGGMEIVAKCRELERLLNAAGVRVKVDDRTNYTPGWKFNDWELKGVPLRLEIGPRDVESCQTRVVRRDTSEARNVPWAEAASTIPAMLETMQKDLFNKAKAKFEASIEQITTFDEVMPALNRRHVVLAPWCEDPETETQIKRETQRLSEIQENADGMTGAMKPLCIPFDQPP--MPEGTRCFFTGRPAKRWCLFGRSY 498
5 -149.0004hvc_A mol:protein length:519 Bifunctional glutamate/proline--tRNA ligase  ali model follow..  53  7.QGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNEDKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLE--PGAPSMGAKSLCIPFKPLCE-LQPGAKCVCGKNPAKYYTLFGRSY 513
6 -147.0004k86_A mol:protein length:535 Proline--tRNA ligase  ali model follow..  51  24..GPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQS-ALEKEKTHVADFAPEVWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIPGEFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALKEALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLE--PGAPSMGAKSLCIPFKPLCE-LQPGAKCVCGKNPAKYYTLFGRSY 529
7 -140.0005xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  49  1.......GAMGIAAKREENFSAWYIDVITKAEMIEYYDVSGCYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSCLEREKDHIEGFAPEVAWVTRAGDTELEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHPTPFIRTREFLWQEGHCAWAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENNEQIPWQNSWGLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTRQELLASCWRLESELCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAAALLEDVHAQMYARAKETMETHRVRVTEWTEFVPTLNRKCLILAPWCGAMECENQVKKDSAEESKVREDARAPSMGAKTLCIPFEQPEEPAEHECICKGCTKPATTWVLFGRSY 512
8 -136.0003ial_A mol:protein length:518 Prolyl-tRNA synthetase  ali model follow..  29  2...AMGGDVTFSLTKTRDTFADWFDAIMDAAELVDRYPVKGCVVFRPYGFFMENAIMRLCEEEYAKVGISQILFPTVIPESFLKKESDHIKGFEAECFWVEKGGLQPLEERLALRPTSETAIYSMFSKWVRSYKDLPLKIHQTCTIFRHETKNTKPLIRVREIHWNEAHCCHATAEDAVSQLSDYWKVIDTIFSDELCFKGQKLRRVCWDRFPGADYSEVSDVVM-PCGRVLQTAGIHNLGQRFSSTFDILYANKANESVHPYLTCAGISTRVLACALSIHGDSGGLVLPPLIAPIHVVIIPIGCGKKNDQQVLGKVNEIADTLSKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDVGKDQVIPITEVMKVSSDELDAYKARLKEKAFAFHNSMVTNCKSFDEIVACIENKGLARFPFYTTEADGEVWDKKLKDA-----------CSAEIRGHNPDEN---VLPGEVCALSGKPAVCYMYCAKSY 512
9 -134.0001h4q_A mol:protein length:477 PROLYL-TRNA SYNTHETASE  ali model follow..  41  1.....MAKEKGLTP-QSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLRKEAEHVEGFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTR-PFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKD-GKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIY-KDESRERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEGGQAVLASRLGGKE-TLPLAALPEALPGKLDAFHEELYRRALAFREDHTRKVDTYEAFKEAVQEG-FALAFHCGDKACERLIQEET---------------TATTRCVPFEAE----PEEGFCVRCGRPSAKRVVFAKAY 477
10 -129.0001nj1_A mol:protein length:501 Proline-tRNA Synthetase  ali model follow..  33  15.MQKPIKKDPNRYHEKMTEFSEWFHNILEEAEIIDQRYVKGMHVWMPHGFMIRKNTLKILRRILDR-DHEEVLFPLLVPEDELAKEAIHVKGFEDEVYWVTHGGLSKLQRKLALRPTSETVMYPMFALWVRSHTDLPMRFYQVVNTFRYETKHTRPIRVREITTFKEAHTIHATASEAEEQVERAVEIYKEFFNS-LGIPYLITRRPPWDKFPGSEYTVAFDTLM-PDGKTLQIGTVHNLGQTFARTFEIKFETPEGDHEYVHQTCYGLSDRVIASVIAIHGDESGLCLPPDVAAHQVVIVPIIFK-KAAEEVMEACRELRSRLEAAGFRVHLDDR-DIRAGRKYYEWEMRGVPLRVEIGPRDLEKGAAVISRRDTGEKVTADLQGIEETLRELMKDILENLRTRAWERMESEIREAETLEEASRIVDEKRIISFMWCGEEECGMDVEEKV---------------RVDILGIQEEGS-------GTCINCGREAPYRAYLARTY 495
11 -115.0001nj8_A mol:protein length:459 Proline-tRNA Synthetase  ali model follow..  35  1.............GSHMLEFSEWYSDILEKAEIYDVYPIKGCGVYLPYGFKIRRYTFEIIRNLLDESGHDEALFPMLIPEDLLAKEAEHIKGFEDEVYWVTHGGKTQLDVKLALRPTSETPIYYMMKLWVKVHTDLPIKIYQIVNTFRYETKHTRPLIRLREIMFKEAHTAHSTKEEAENQVKEAISIYKKFFDT-LGIPYLISKRPEWDKFPGAEYTMAFDTIF-PDGRTMQIATVHNLGQNFSKTFEIIFETPTGDKDYAYQTCYGISDRVIASIIAIHGDEKGLILPPIVAPIQVVIVPLIFKGKE-DIVMEKAKEIYEKL-KGKFRVHIDDR-DIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKFQVDETQLMEVVEKTLNNIMENIKNRAWEKFENFITILEDIDEIKNILEKRGVILVPFKEEIYNEELEEKV----------------EATILGETEYK-------GNKYIAIA----------KTY 459
12 -90.4002j3l_A mol:protein length:572 PROLYL-TRNA SYNTHETASE  ali model follow..  19  2...KQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQV-AAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAE-LWKESGRYETYGPNLYRLKDRNDRD----YILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSRSGLLRGREFIMKDGYSFHADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKEFMAISEIGEDTTKGIEIGHIFKLGTRYSDAMGATVLDENGREKSVIMGCYGIGSRLLSAIVEQNADERGINWPTGIAPFDLHVVQMNVKD---EYQTKLSQEVEAMMTEAGYEVLVDDR-NERAGVKFADADLIGCPIRITVGKKAVD-GVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEV........................................................................................................ 571
13 -83.9002i4l_A mol:protein length:458 Proline-tRNA ligase  ali model follow..  16  13.SHMRLSRFFLPILKEPKEAEIVSHRLMLRAGMLRQE-AAGIYAWLPLGHRVLKKIEQIVREEQNRAGAIELLMPTLQLAD-LWRESGRYDAYGPEMLRIADRHKRE----LLYGPTNEEMITEIFRAYIKSYKSLPLNLYHIQWKFRDEQRPRFGVMRGREFLMKDAYSFDVDEAGARKSYNKMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHEESEVPEANRLNTRGIEVGQIFYFGTKYSDSMKANVTGPDGTDAPIHGGSYGVGVRLLGAIIEACHDDNGIIWPEAVAPFRVTILNL---KQGDAATDAACDQLYRELSAKGVDVLYDDT-DQRAGAKFATADLIGIPWQIHVGPRGLAEGKVELKRRSDGARENLALADVVARLT................................................................................................................. 452
14 -81.1005ucm_A mol:protein length:579 Proline--tRNA ligase  ali model follow..  20  1MAMRTSQYLLSTLKETPADAVVISHQLLLRAGMIRRL-ASGLYTWLPMGLRVLRKVETIVREEMNAAGALEVLMPAVQPAE-LWQESGRWEQYGPELLRLKDRHERE----FCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQADNGSIGGSGSHYAANIEKAEAVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGSRVVAAAIEQNHDERGILWPSALAPFQIALVPLKYET---ESVKQATDKLYAELTAAGFEVLLDDRDKKSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLSR............................................................................................................ 573
15 -72.1004p3n_A mol:protein length:415 Threonine--tRNA ligase, cytoplasmic  ali model follow..  16  2................GSSSSGDHRKIGRDQELYFFHESPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSR-LWMTSGHWQHYSENMFSFEVE-----KELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGRPVIVHRAILGSVERMIAILTENYGGK----WPFWLSPRQVMVVPV------GPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEE.................................................................................................... 408
16 -70.5004hwt_A mol:protein length:413 Threonine--tRNA ligase, cytoplasmic  ali model follow..  16  1...................MARDHRKIGRDQELYFFHESPGSCFFLPKGAYIYNALIEFIRSEYRKRGFQEVVTPNIFNSR-LWMTSGHWQHYSENMFSFEVE-----KELFALKPMNCPGHCLMFDHRPRSWRELPLRLADFGVLHRNELSGALGLTRVRRFQQDDAHIFCAMEQIEDEIKGCLIEVWDQAEKQLENSLNEFGEKWELNSGDGAFYGPKIDIQIKDAIGRYHQCATIQLDFQLPIRFNLTYVSHDGRPVIVHRAILGSVERMIAILTENYGGK----WPFWLSPRQVMVVPV------GPTCDEYAQKVRQQFHDAKFMADIDLDPGCTLNKKIRNAQLAQYNFILVVGEKEKISGTVNIRTRDNKVHGERTISETIERLQQLKEFRSKQAEEE.................................................................................................... 404
17 -68.9003a31_A mol:protein length:471 Probable threonyl-tRNA synthetase 1  ali model follow..  12  1MASGQDKTHIDYAYELDITVKPDSRVPVFNREFATFT-GAGVPLFSLGGGPIRYALAEVLAKFHARRGYYVVETPIIASTE-LFKVSGHIEFYRNNMYLFDIE-----GHEFAVKPMNCPYHILLFLNEVASKLPLPFKVFEFGRVHRYEPSGSIGLLRVRGFTQDDAHIIVPGGRVIDVVYDVFEGAEEALREAASRINEKYGIDIVELEGEAAFYGPKLDFIEESGVSKEWQMGTIQFDFNLPRRFRLYDVVREEEVYIIHRALLGSIERFLGVYLEHRRGR----MPFTLAPIQFAVIAVKTGGEVDREIEDLASSIAKGLLDKGFRVAVKGSSKTGLSSDVRHIESTAKPAVVFIGAKEVREKVLDVRVFDLESMKRRRLAIAYGDAADAVENLAAVAEELESPVRSLSGQAPRIPADFSFML.............................................................................. 471
18 -64.9004hwo_A mol:protein length:411 Threonine--tRNA ligase  ali model follow..  18  1...................MARDHRKIGKQLDLYHMQEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRV-LWEKTGHWDNYKDAMFTTSSE-----NREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNEPVMIHRAILGSMERFIGILTEEFAGF----FPTWLAPVQVVIMNI------TDSQSEYVNELTQKLSNAGIRVKADLR-NEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE.................................................................................................... 403
19 -63.5001nyq_A mol:protein length:645 threonyl-tRNA synthetase 1  ali model follow..  16  210.NNKMLQRIYGTAFFDKKELERDHRKIGKELELFTNSQGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVD-LYKTSGHWDHYQEDMFPPM---QLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGRPVVIHRGVVSTMERFVAFLTEETKGA----FPTWLAPKQVQIIPVNVDLH-----YDYARQLQDELKSQGVRVSIDDR-NEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR........................................................................................................ 645
20 -63.1003ugq_A mol:protein length:460 Threonyl-tRNA synthetase, mitochondrial  ali model follow..  16  5.SSGLVPRGSHMASATSATPATMTSMVSQRQDLFMTDPSPGSMFFLPNGAKIFNKLIEFMKLQQKKFGFNEVVTPLIYKKT-LWEKSGHWENYADDMFKVETTDEE--KEEYGLKPMNCPGHCLIFGKKDRSYNELPLRFSDFSPLHRNEASGALGLTRLRKFHQDDGHIFCTPSQVKSEIFNSLLKVWNHAEQVLKEILEESGKPWKLNPGDGAFYGPKLDIMVTDHLRKTHQVATIQLDFQLPERFDLKFKDQDNSPIMIHRATFGSIERFMALLIDSNEGR----WPFWLNPYQAVIIPVNTKNVQLRNELEADDMEPVPLNDWHFNVDLDIRNE-PVGYRIKSAILKNYSYLIIVGDEEVQLQKYNIRERDNRKSEKLTMSQIWEKFIELEKNYK.......................................................................................................... 454
21 -59.4001qf6_A mol:protein length:642 THREONYL-TRNA SYNTHETASE  ali model follow..  18  211.NNKMLQRIYGTAWADEEAAKRDHRKIGKQLDLYHMQEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRV-LWEKTGHWDNYKDAMFTTSSE-----NREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNVPVMIHRAILGSMERFIGILTEEFAGF----FPTWLAPVQVVIMNI------TDSQSEYVNELTQKLSNAGIRVKADLR-NEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE.................................................................................................... 642
22 -47.2001b76_A mol:protein length:442 Glycine--tRNA ligase  ali model follow..  14  1............AASSLDELVALCKRRGFIFQSSEIYGLQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRL-VLHYSGHEATFADPMVDNAKARYGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRPGEDEESSAHYAKATVDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARLRNEHSTQRLAYRDPETGKWFVPYVIEPSDRGVLALLAEAFTREELPNGEERIV----LKLKPQLAPIKVAVIPL---VKNRPEITEYAKRLKARLLALGLGRVLYEDTG-NIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR............................................................................................................. 441
23 -40.5002cim_A mol:protein length:522 SERYL-TRNA SYNTHETASE  ali model follow..  17  177.AKAEHWNLLWQREPMEHPFKEDPTQAMMKEGWLKRGSSRGQWIHGPQSARIFRTFEKIVLEELEPLGYREMIFPKLVTWEVW-MKSGHAKGVYPEIYYVCPPQTRDPDYIGGMCYAQCPPFWMYVAGETLPNEEIPVKVFDRGTSHRYESGGIHGIERVDEFHRIEIVWI-GTKEEVLKCAEELHDRYMHIFNDILDIEWRKQEGLLGLAEENTVGTTDYEACLPPDGEWLEFQNVSINGDKYPKGFNVKLQSGD----ELWSGCSGVGERWAAVFLAQKGLDPA-NWP---EEFRNRVGEMPKGIR..................................................................................................................................................................................................... 514
24 -39.5002pme_A mol:protein length:693 Glycyl-tRNA synthetase  ali model follow..  14  47RKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFY-YGGVSGLYDFGPVGCALKNNIIQTWRQHFQEEQILEIDCTMLTPEP-VLKTSGHVDKFADFMVKDVKNGEGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVVIEPSFGLG-RIMYTVFEHTFHVREFSFPAVVAPFKCSVLPLSQN----QEFMPFVKELSEALTRHGVSHKVDDSSG-SIGRRYARTDEIGVAFGVTIDFDTVNKTTATLRDRDSMRQIRAEISELPSIVQDLANGNIADVEARYPLFEGQETGKKETIEELE................................................................................. 687
25 -38.4001ati_A mol:protein length:505 GLYCYL-TRNA SYNTHETASE  ali model follow..  15  1................AASSLDELVALCKRRGFI-YGGLQGVYDYGPLGVELKNNLKQAWWRRNERDDMEGLDASVLTHRL-VLHYSGHEATFADPMVDNRITKKGGRGLLAYLRPETAQGIFVNFKNVLDATSKLGFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRPGEDEYWHVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYRFPH-LELEGIAQRTDFDLGSHTKDQEALGITARVLRNEYVIEPSAGVDRGVLALLAEAFTREE-LKLKPQLAPIKVAVIPL---VKNRPEITEYAKRLKARLLALGLGRVLYEDTG-NIGKAYRRHDEVGTPFAVTVDYDTIGQSTVTVRDRDTMEQIRLHVDELEGFLRERLR............................................................................................................. 504
26 -32.9003qne_A mol:protein length:485 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  14  123.ENNELVRTWTPENYKKAPAKLSHHEVLLRLDGYDPEVGHRGYFLRNYGVFLNQALINYGLSFLSSKGYVPLQAPVMMNKE-VMAKTAQLSQFDEELYKVI----DGEDEKYLIATSEQPISAYHAGEWFSPAEQLPVRYAGYSSCFRREAKDAWGIFRVHAFEKIEQFVLTEPEK-SWEEFDRMIGCSEEFYQSLGLPYRVVGIVSG-ELNNAAAKKYDLEAWFPFQQEYKELVSCSNCTDYQSRNLEIRCGIKQQNQQHCLNSTLSATERTICCILENYQKEDGLVIPEVLRKY-----------PGEPEFIPYIKELPKNTTSVKKAKGKNPK-NTTSVKKAKGKNGS.......................................................................................................................................................... 478
27 -29.6005c51_B mol:protein length:485 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  10  49...ELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPV-LHHKPGPLLPGDSAFRLVSAETLQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQIVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNF---ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVVLSVNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVG---RGPTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKN......................................................................................................... 484
28 -29.4002g4c_A mol:protein length:474 DNA polymerase gamma subunit 2  ali model follow..  10  30.HAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPV-LHHKPGPLLPGDSAFRLVSAETLQLVTFLENVLKTSGKLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQGVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNF---ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVVLSVNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVG---RGPTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKN......................................................................................................... 467
29 -29.3004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  15  12.GSHMNIAVLPNSPDTAPQIADPLDHLADKLFH--SMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQL-EKSGYLKSFPNLLGCVCGLHGTEREADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRRE--PSKHLDRLQSFRMRE-YVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYAKMLANNQRDQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGE----PAHTGCVAFGDRLAVAMFHTHGTDLS-AWPAKVRDI................................................................................................................................................................................................................. 323
30 -28.9004ztu_B mol:protein length:472 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  10  22SHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPV-LHHKPGPLLPGDSAFRLVSAETLQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDVNKRLPYGLAQIGVCFHPVFDTKQGVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNF---ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVVLSVNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVG---RGPTLELRQVCQGLFNELLENGISVGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKN......................................................................................................... 460
31 -28.9003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  14  12.GSHMNIAVLPNSPDTAPQIADPLDHLADKLFH--SMGSDGVYARTALYESIVERLAALITS-HREAGTEALRFPPVMSRAQL-EKSGYLKSFPNLLGCVCGLHGTEREADLVLSPAACYPVYPIAASRGPL-PKGGLRFDVAADCFRRE--PSKHLDRLQSFRMRE-YVCIGTPDDVSDFRERWMVRAQAIARDLGLTFRVDYAQMKAVSQKQQQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDANGE----PAHTGCVAFGDRLAVAMFHTHGTDLS-AWPAKVRDI................................................................................................................................................................................................................. 323
32 -27.7001g5h_A mol:protein length:454 MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT  ali model follow..  12  5.YAGPADGTQQPDAPEHAVAREALVDLCRRRHFLSGTPLSGCHAFGPLGVELRKNLASQWWSSMVVFREQVFAVDLHQEPGSSQPRDSAFRLVSPESEQLVAFLENLLKTSGKLRATLLHGALEHYVNCLDLVNKLPFGLAQIGVCFHNSNQTPSSVTRVGEKTEASLVWF-TPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYSF---EPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVVLSVSGDVDLGTLAYLYDSFQLAENLKLHPCLAPIKVALDVG---KGPTVELRQVCQGLLNELLENGISVGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDFLVKYLASASN......................................................................................................... 442
33 -25.1003ikl_A mol:protein length:459 DNA polymerase subunit gamma-2, mitochondrial  ali model follow..  11  101..............................................PLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKP-------------------GPLLPGDSAFRGGLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQIVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNF--KELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVVLSVNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVG---RGPTLELRQVCQGLFNELLENGISVWPGETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKN......................................................................................................... 452
34 -24.7003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  15  1.............MAMGTLEAQTQGPGSMQKNMVETEPVQGCRDFPPEAMRCRRHLFDVFHATAKTFGFEEYDAPVLESEELYIRKAG--EEITEQMFNFITKGGHR----VALRPEMTPSLARLLLGKGRSLL-LPAKWYSIPQCWRYE-AITRG--RRREHYQWNMDIVGVKSVSAEELVCAACWAMRSLVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAYNLLTTYGSPTPIPCAGFGFGDCVIVELLQEKR-----LLPDIPHVVDDVVIPFD------ESMRPHALAVLRRLRDAGRSADII--DKKKVVQAFNYADRVGAVRAVLVAPEEWERGEVQVKMLREGTGKEEGGAERGFAVPL................................................................................................................ 446
35 -24.2003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  13  1.............MAMGTLEAQTQGPGSMQMNMVETEPVQGCRDFPPETMRLRKYLFDVFHSTARKFGFEEYDSPVLESEELYIRKAG--EEITEQMFNFITKGGHR----VALRPEMTPSLARQLLAKGRSLL-LPAKWYSIPQCWRYE-AITRG--RRREHYQWNMDIIGVKSVSSEELVCAACTAMQSLVDAITSTLSLKTIDEIAQRIGEEHEAVRELRDFITQIEAYGFGDWVIFDASVVRGLAYNLLTTYGSPTAVPCVGFGFGDCVIVELLNEKK-----LLPELHHVVDDLVIPFD------ETMRPHALSILRRLRDAGRSADIV--DKKKVVQAFNYADRIGALRAVLVAPDEWARGEVRVKMLREGAGREEGANERGIVLPV................................................................................................................ 446
36 -23.4001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  12  4.................................LQIEKIRGFRDFYPEDMDVEKFIFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSG--EELLQQTYSFVDKGGRE----VTLIPEATPSTVRMVTS--RKDLQRPLRWYSFPKVWRYE-EPQAG--RYREHYQFNADIFGSDSPEADAEVIALLGLQDIYEIRINSRKIMEEIIGGMTSSDPFSVFSIIDRYHKISREEFRYDFSIVRGLSYYTGIVFEAYDRSGQFRAILGG--GRYDNLASLMSGESVPAVGFGM-IPREKKSVYICRVG------KINSSIMNEYSRKLRERGMNVTVE--MERGLSAQLKYASAIGADFAVIFGERDLERGVVTIRNMYTGSQENVGLDSVVEHLISQATL............................................................................................................ 427
37 -23.3005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  10  1..............................MAMSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGD-DIVEKEMYTFFDKGNPP--ESLTLRPEGTAGCVRALVEH-NLLRGATPRVWYMGPMFRYE-KPQKG--RYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTRTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQSVPAVGFAM----VRDCEAFLVAE------PAYQSKALVLAEQLRDQLEAANSNIRSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK............................................................................................................ 432
38 -22.9001qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  12  5......................................PRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGD-DVVQKEMYTFKDKGDRS----ITLRPEGTAAVVRSYEHKMQGNPNQPIKLYYNGPMFRYE-RKQKG--RYRQFNQFGVEAIGAENPSVDEVLAMVMHIYQSFGLKHLKLVIDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTDPMRILDCKVDRAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALLDIEENLDLFIVTMG------DQADRYAVKLLNHLRHNGIKADKD--LQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK................................................................................................................ 420
39 -22.9005c53_B mol:protein length:903 Pol gamma B  ali model follow..  13  373LLENGISVWPGYLETMQSSLEQLYSKVLVTETTLE----NGLIHLRSRDTTMISKLKDFLIKYISRSRVAVRACHKVCR-CLLSGFGGRVDAGQPELLTERSSPKGG-DSAFRLRENLLHGALEHYVNCLDLVNRLPYGLAQIGVCFHPVFDTKQGVKSIGEKTEASLVWF-TPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNF--KELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVVLSVNGDLDRGMLAYLYDSFQLTENLKLHPCLAPIKVALDVG---RGPTLELRQVCQGLFNELLENGISVWPGETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKN......................................................................................................... 902
40 -22.8003w3s_A mol:protein length:527 Type-2 serine--tRNA ligase  ali model follow..  14  173VTKVEPGTVVDESGPRRIRFRGDVTEEARRRGWVKEFPGRGQWIYTPPMAALFEVLRDFLLERVRKLGFEPALFPKLIPLETM-FRMRYLHGLPDGMYYVCPPKRDPEDPGYVLAPAQCEPFYELLRDEVVDPERLPIKLYDCGWTYRWEGGAAKGLERVNEFQRIEH-VWIAEPEEAYRIRRELLEATKRVAEELELEWKVVVSDEDRDIELPDVPSYEFEVYLPFKGERSSEEAWISVGNVHGEHFVDGFNVKEKSGRTLFTGCAGLGTRWVVGLLAQHGFYPY-EWPEPI.................................................................................................................................................................................................................... 505
41 -22.6001ser_A mol:protein length:421 PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))  ali model follow..  14  113.GEEANREIKRVGGPPEFSFPPLDHVALMEKNGWWEPRISRSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAF-LGTGHFPAYRDQVWAIA-------ETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAKDVRGLMRVHQFHKVEQYVLTESLEASDRAFQELLENAEEILRLLELPYRLVEVATG-DMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTNTALATPRILAMLLENHQLQDGVRVPQALIPY................................................................................................................................................................................................................. 411
42 -22.5003vbb_A mol:protein length:522 Seryl-tRNA synthetase, cytoplasmic  ali model follow..  16  161..............DCTVRKKYSHVDLVVMVDGFEGAVVAGSYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVM-QEVAQLSQFDEELYKVIGKGSEKSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTCFRQEVRDTRGIFRVHQFEKIEQFVYSSPHNKSWEMFEEMITTAEEFYQSLGIPYHIVNIVSG-SLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKKVEFVHMATMCATTRTICAILENYQTEKGITVPEKLKEFLQELIP-KQHEGSKKKAAARDVTLENRLQNMEVTDALE........................................................................................................................................................................... 516
43 -22.3004rdx_A mol:protein length:423 Histidine--tRNA ligase  ali model follow..  12  1...............................GPMTARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGA-DIVRKEMFTFQDRGGRS----LTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAE-RPQKG--RYRQFHQVNYEALGSENPILDEAVVLLYECLKELGLRRLKVKLDPEDRARYNAYLREVLSPHREALSEDSKERLELNPMRILDSKSERAFEVHHEEIGAQSALGGGGRYDGLSELLGG-VPGVGFAFGVFGLPEEKGPDLYLIPLT------EEAVAEAFYLAEALRP-RLRAEYA--APRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG............................................................................................................. 423
44 -22.0004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  11  60............................ESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDS---KLIYDLKDQGGEL----LSLRY-----LTVPFARYLAMNKLTNIKRYHIAKVYRRD-NPAMTRGRYREFYQCDFDIAGNFDPMIPDA--ECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKGLDYYTGVIYE-RYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRL-------KIRTTETQVLVASAQ------KKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ............................................................................................................ 515
45 -21.9003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  12  1........................SNAMAKNDKINFSTPSGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKGNQGDNIQAEKDKSGDTGSEA----RALKFDQTVPLAAYIARHLNDLT-FPFARYQMDVVFRGE-RAKDG--RFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFINPEQTQKIIDFVKIDGSVDDVLDKLKHLSQTLPESEQFNLGVSELELNYYTGTVYETTLIGHEALGSICSGGRYGISTRLISRL-----LKAGILNTLPPTPAQVVVVNMQ------DELMPTYLKVSQQLRQAGLNVITN--EKRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRLT............................................................................................................. 465
46 -21.8004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  11  12.................................FVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDS---KLIYDLKDQGGEL----LSLRY-----LTVPFARYLAMNKLTNIKRYHIAKVYRRD-NPAMTRGRYREFYQCDFDIAGNFDPMIPDA--ECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKGLDYYTGVIYE-RYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRL-------KIRTTETQVLVASAQ------KKLLEERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ............................................................................................................ 462
47 -21.7003err_A mol:protein length:536 fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus  ali model follow..  15  236..............PEFSFPPLDHVALMEKNGWWEPSQVSGSYALKGDLALYELALLRFAMDFMARRGFLPMTLPSYAREKAF-LGTGHFPAYRDQVWAIA-------ETDLYLTGTAEVVLNALHSGEILPYEALPLRYAGYAPAFRSEAKDVRGLMRVHQFHKVEQYVLTEASEASDRAFQELLENAEEILRLLELPYRLVEVATG-DMGPGKWRQVDIEVYLPSEGRYRETHSCSALLDWQARRANLRYRDPEGRVRYAYTNTALATPRILAMLLENHQLQDGVRVPQALIPY................................................................................................................................................................................................................. 520
48 -21.6002dq3_A mol:protein length:425 Seryl-tRNA synthetase  ali model follow..  13  132..............RKFDFEPKPHWEIGERLGILDFKRGSRFTVIAGWGARLERALINFMLDLHTKKGYKEICPPHLVKPEIL-IGTGQLPKFEEDLYKCE-------RDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAKDIRGIIRQHQFDKVELVKI-VHPDTSYDELEKLVKDAEEVLQLLGLPYRVVELCTG-DLGFSAAKTYDIEVWFPSQNKYREISSCSNCEDFQARRMNTRFKDSKTGKNRFVHTLNGSGLRTLAAILENYQQEDGVVVPEVLRDY................................................................................................................................................................................................................. 416
49 -21.4001v95_A mol:protein length:130 Nuclear receptor coactivator 5  ali model follow..  14  7.....................................................................................................................................................................................................................................................................................................GPVDCSVIVV------NKQTKDYAESVGRKVRDLGMVVDLI-NTEVSLSQALEDVSRGGSPFAIVITQQHQIHRSCTVNIMFGTEHRNMPQADAMVLVARNYERYKNECREKERE................................................................................................. 118
50 -21.3001wle_A mol:protein length:501 Seryl-tRNA synthetase  ali model follow..  16  173..............PAFSFQPRGHLEIAEKLDIIRQSHVSGSYYLRGAGALLQHGLVNFTLNKLIHRGFTPMTVPDLLRGVVF-EGCGMTPNAKPSQIYNIDPSRFE---DLNLAGTAEVGLAGYFMDHSVAFRDLPIRMVCSSTCYRAETKEPWGLYRVHHFTKVEMFGVTGPGEQSSELLEEFLSLQMEILTELGLHFRVLDMPTQ-ELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTATGCAVPRLLIALLESYQQKDGVLVPPALQPY................................................................................................................................................................................................................. 461
51 -20.9002dq0_A mol:protein length:455 Seryl-tRNA synthetase  ali model follow..  15  153..............EILEWKPKLHVDLLEILGGADFARASRFYYLLNEIVILDLALIRFALDRLIEKGFTPVIPPYMVRRFVE-EGSTSFEDFEDVIYKVE-------DEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGVSPCFRKEAKDTKGIFRVHQFHKVEQFVY-SRPEESWEWHEKIIRNAEELFQELEIPYRVVNICTG-DLGYVAAKKYDIEAWMPGQGKFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIRAIVAILENHQEEDGVRIPKVLWKY................................................................................................................................................................................................................. 437
52 -20.8002el9_A mol:protein length:431 Histidyl-tRNA synthetase  ali model follow..  11..................................NIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGE-DVVEKEMYTFEDRNGDS----LTLRPEGTAGCVRAGIEH-GLLYNQEQRLWYIGPMFRHE-RPQKG--RYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSRANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVFEWVTNSLGSQGTVCAGGRYDGLVEQLGG-TPAVGFAMGLPEFKADPVVDIYLVASG------ADTQSAAMALAERLRDELPGVKLMNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG............................................................................................................. 431
53 -20.7003lsq_A mol:protein length:484 Seryl-tRNA synthetase  ali model follow..  14  168..............TTKRAKLNHVSIMERLGMMDTSTSMAGSYVLKGGLVQLQVALVSYSLDFLVKRGYTPFYPPFFLNRDVM-GEVAQLSQFDEELYQVSGD-----GDKKYLIATSEMPIAAYHRGRWFTELKEPLKYAGMSTCFRKEARDTLGIFRVHQFDKIEQFVVCSPREESWRHLEDMITTSEEFNKSLGLPYRVVNICSG-ALNNAAAKKYDLEAWFPASGAFRELVSCSNCTDYQSQSVNCRYGPNLRGTAAQNVKEY-AITRTMCCICENYQTEEGVVIPDVLRPY................................................................................................................................................................................................................. 460
54 -20.3004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  11  5..............TLEAQTQGPGSMTEQKRKLEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLFTRGIGE-DIVEKEMYSFVDALN---GENLTLRPENTAAVVRAAIEH-NMLYDGPKRLWYIGPMFRHE-RPQRG--RYRQFHQVGVEALGFAGPDADEIVMMCQRLWEDLGLTGIKLEILAEERAAHRVELIKYLEQHADKLDDDAQRRLYTNPLRVLDTKNPAVFEWVTDKLGAQGTVAAGGRYDPLIEQLGG-TAACGWAMGI---PEQEGVDVYVVHQG------DAAREQAFIVAERLRDTGLDVILHDGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPGEKSVQQSVPVESLTEFLINAMVATAEDGDD..................................................................................................... 461
55 -20.0006blj_A mol:protein length:485 Serine-tRNA ligase  ali model follow..  15  176..............PETGYKCLKHIDIMRKLGGLATTQVGGGYFLLGDLVRMNLALQNYAIDFLAKKGYMPIYTPFFMTKEQM-KKVAQLSQFDEELYTVTGE-----GEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVKDTLGIFRVHQFEKIEQFVVTSPKDNSWEMFDEMIGNSEAFYQSLGIPYRVVNIVSG-ALNNAAAKKFDLEAWFPGADEG-ELVSCSNCTDYQTRRLEVKYKKQGSEVEFCHMSTLTATSRTLCCIVENYQTPEGVNVPEVLQPY................................................................................................................................................................................................................. 468
56 -18.5002lw7_A mol:protein length:170 Histidine--tRNA ligase, cytoplasmic  ali model follow..  14  68.....................................................................................................................................................................................................................................................................................................TETQVLVASAQ------KKLLEERLKLVSELQDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDLVEEIKRRTGQ............................................................................................................ 165
57 -18.2004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  11  4LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDT-------ELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLNFCQM--SGCTRENLESIITDFLNHL......................................................................................................................................................................................................................................................................................................................... 184
58 -17.9005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  12  4LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-------DNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLAFAQMGSGCTRE-NLESIITDFLNHL......................................................................................................................................................................................................................................................................................................................... 184
59 -17.2004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  11  21LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGI-------DNDTELSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLNFCQM--SGCTRENLESIITDFLNHL......................................................................................................................................................................................................................................................................................................................... 201
60 -17.1003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  11  18LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDT-------ELSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLVFWQM--SGCTRENLESIITDFLNHL......................................................................................................................................................................................................................................................................................................................... 198
61 -16.9004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  11  3LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEEREYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQI-------FRVDKNFCLRPMVAPNIFNYARKLDRALPD-PIKIFEIGPCYRKESDGKE---HLEEFTMLNFFQMGSGCTREN...................................................................................................................................................................................................................................................................................................................................... 171
62 -15.8002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  11  40...NASGEQLEMGFSDALSRDRAFQGIEHQLMSQGKRHLE--QLRTVKHRPALLELEEKLAKALHQQGFVQVVTPTIITKSALAKMTIGEDH----------SQVFWLDGKKCLRPMLAPNLYTLWRELERLWDK-PIRIFEIGTCYRKESQGAQ---HLNEFTMLNLTELGTPLEERHQRLEDMAR.............................................................................................................................................................................................................................................................................................................................. 210
63 -15.0003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  10  14.......................................FGMRDTLPEWYKTKKNICDQMTEEINLWGYDMIETPTLEYYETVGVVSAILD---QQLFKLLDQQG----NTLVLRPDMTAPIARLVASSLKD-RAYPLRLAYQSNVYRAQQNEG----KPAEFEQLGVELIGDGTASADEVIALMIAALKRAKSRLMNLLSLRGGRAAIEEARGLIQTEKGKTALAEMTKLYEVLESYGASEYVKFDLTLVYTG-SGGRYDELLSKFHRPAQATGFGVRIDLLVEALNGEIISNGHEQTCILFSNERRFE------AIELARKKRANGEAVVLQDLAG-VTDVDAMSSNYQDVIYCIGTAGRGGEDA.......................................................................................................................................... 400
64 -14.1002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  12  21LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDL-IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDT----------KQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGK----HLEEFTMLNFCQMGSGCTRE-NLESIITDFLNHL......................................................................................................................................................................................................................................................................................................................... 201
65 -13.7004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  11  65...........................................IYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDT---------SKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPD-PIKIFEIGPCYRKESDGKE---HLEEFTMLSFIQMGSGCTREN-----LESIITDFLNHLGIDFKIVGDSCM-----------VYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKP------------GAGFGLERLLKVKHDFKN.............................................................................................................................................................................................................................. 267
66 -11.9006FTT Entity 1(prereleased)  ali follow..  10  5.......................................DGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESLLSGAS--EDLKRQTFKIIDQLTGRL---MGIRA---DITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGL----GSRTPLQLGAEIFGCESIAADELIDVLFSMINSL--------------------------------------DMSAVLHVDLGKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWCAVSID---HYHTGIVF-NGYINSETQPLVRGGRGMKSNQLATNQPRQATGFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLL----QQVASLRQQGYRVTMPLTAEDMPVGLTHRLS..................................................... 377
67 -11.9005m8h_A mol:protein length:388 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  10  5.......................................DGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESLLSGAS--EDLKRQTFKIIDQLTGRL---MGIRA---DITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGL----GSRTPLQLGAEIFGCESIAADELIDVLFSMINSL--------------------------------------DMSAVLHVDLGKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWCAVSID---HYHTGIVF-NGYINSETQPLVRGGRGMKSNQLATNQPRQATGFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLL----QQVASLRQQGYRVTMPLTAEDMPVGLTHRLS..................................................... 377
68 -11.7003rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  1.............SNAMNGTRSAWGARAWEAVRGFADRPPGMQDGYPDFAKRRRAVETRLLSFVEDAGYEPVTSGLFEYVDTLLRARS--PESSRDWIRLFDGGG----DAVALRPEMTPSIARMAAPRVAA-GRTPIRWCYCERVYRRTLSWASG--KAAESTQVGIERIGEEASVDVDVLRLLHEASAAA......................................................................................................................................................................................................................................................................................................................... 177
69 -11.0001z7m_A mol:protein length:344 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  12  10.............................RMEKINYLLPEESAEMTLNQVKSLRQIEGRLRKLFSLKNYQEVMPPSFEYTQLYTALESNGKTFQEKMFQFIKHEG----QSITLRY---DFTLPLVRLYSQIKDSTSARYSYFGKIFRKEKRHK----RSTENYQIGIELFGESADKSEEILSLALQVIEQL---------------------------GLNKTVFEIGSAKFFQRLCQLADGSTELLTELLLKKDLSGLNAFIEKNNFSKELRGLLKEIFITN------------ELSRLENLVTNTKDDVLISSFDQLKEFSEKLSMIKPIIIDLGMVPKMDYYKAYSSAANQPILSGGR-------QLLSNFQEEAFAIGFCCHMDTILKALERQELEEDND.................................................................................................... 338
70 -9.0804o2d_A mol:protein length:620 Aspartate--tRNA ligase  ali model follow..  10  116VLGESAPLPFQLDEQAGEEARLKYRYLDLRREGPGNA------------LRLRSKVNAAARSVLAEHDFVEIETPTLTRST------------------------PEGARDFLVPARLQPGSFYALPQSPQLFKQLLMRYYQIARCYRDEDFRA----RQPEFTQLDMEMSFVEADDVIAISEQVLAVWATIGYDLPLPLPRISYEEAMRRFGSDKPDLRFGIELVECTEYFKDTTAKNLSDAERDGLVAHVGANPGDCIFFAAGPAKGARALLGATRIEIAKRLDLIDPNAWAFTWVVDFPMFEAADEATAAGDVAVGSGA---TAMHHAFTAPKPDSVDTFDSDPGNALSDAYDIVCNGNEIGGGSIRIHRRDIQERVF----AMMGIDHDEAQEKFGFLLDAFSYGAPPHGGIAFGWDRITALL----------AGVDSIREVIKSGGGVDPLTDAPAPITPQQRKESGIDAKPREDKPKEDAK.................. 611

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Awobuluyi M, Yang J, Ye Y, Chatterton JE, Godzik A, Lipton SA, Zhang D. Subunit-specific roles of glycine-binding domains in activation of NR1/NR3N-methyl-D-aspartate receptors. Mol Pharmacol. 2007 Jan;71(1):112-22. Epub 2006 Oct 17.