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Query: 5x6c_A mol:protein length:553 O-phosphoserine--tRNA(Cys) ligase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSMKLKHKRDDKMRFDIKKVLELAEKDFETAWRETRALIKDKHIDNKYPRLKPVYGKPHPVMETIERLRQAYLRMGFEEMINPVIVDEMEIYKQFGPEAMAVLDRCFYLAGLPRPDVGLGNEKVEIIKNLGIDIDEEKKERLREVLHLYKKGAIDGDDLVFEIAKALNVSNEMGLKVLETAFPEFKDLKPESTTLTLRSHMTSGWFITLSSLIKKRKLPLKLFSIDRCFRREQREDRSHLMSYHSASCVVVGEDVSVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPETQTEVYAYHPKLGEWIEVATFGVYSPIALAKYNIDVPVMNLGLGVERLAMIIYGYEDVRAMVYPQFYEYRLSDRDIAGMIRVDKVPILDEFYNFANELIDICIANKDKESPCSVEVKREFNFNGERRVIKVEIFENEPNKKLLGPSVLNEVYVYDGNIYGIPPTFEGVKEQYIPILKKAKEEGVSTNIRYIDGIIYKLVAKIEEALVSNVDEFKFRVPIVRSLSDINLKIDELALKQIMGENKVIDVRGPVFLNAKVEIKLast
1 -168.0005x6c_A mol:protein length:553 O-phosphoserine--tRNA(Cys) ligase  ali model  100  1MGSSMKLKHKRDDKMRFDIKKVLELAEKDFETAWRETRALIKDKHIDNKYPRLKPVYGKPHPVMETIERLRQAYLRMGFEEMINPVIVDEMEIYKQFGPEAMAVLDRCFYLAGLPRPDVGLGNEKVEIIKNLGIDIDEEKKERLREVLHLYKKGAIDGDDLVFEIAKALNVSNEMGLKVLETAFPEFKDLKPESTTLTLRSHMTSGWFITLSSLIKKRKLPLKLFSIDRCFRREQREDRSHLMSYHSASCVVVGEDVSVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPETQTEVYAYHPKLGEWIEVATFGVYSPIALAKYNIDVPVMNLGLGVERLAMIIYGYEDVRAMVYPQFYEYRLSDRDIAGMIRVDKVPILDEFYNFANELIDICIANKDKESPCSVEVKREFNFNGERRVIKVEIFENEPNKKLLGPSVLNEVYVYDGNIYGIPPTFEGVKEQYIPILKKAKEEGVSTNIRYIDGIIYKLVAKIEEALVSNVDEFKFRVPIVRSLSDINLKIDELALKQIMGENKVIDVRGPVFLNAKVEIK 553
2 -138.0002du3_A mol:protein length:534 O-phosphoseryl-tRNA synthetase  ali model follow..  49  1..............MKFDPQKYRELAEKDFEAAWKAGKEILAERSPNELYPRVGFSFGKEHPLFATIQRLREAYLSIGFSEVVNPLIVEDVHVKKQFGREALAVLDRCFYLATLPKPNSAEKIRQIEAITKREVDSKPLQEIFHRYKKGEIDGDDLS-----YLIAEVLDVDDITAVKILDEVFPEFKELKPISSTLTLRSHMTTGWFITLSHIADKLPLPIKLFSIDRCFRREQGEDATRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQTEVFSSTKYSDGWIEIATFGIYSPTALAEYDIPYPVMNLGLGVERLAMILYGYDDVRKMVYPQIHGEIKLDLDIAREIKVKEVPQTAVGLKIAQSIVETAEKHASEPSPCSFLA---FEGEMMGRNVRVYVVEEEENTKLCGPAYANEVVVYKGDIYGIPKTKK---------WRSFFEEGVPTGIRYIDGFAYYAARKVEEAAMREQEEVKVKARIVENLSDINLYIHENVRRYILWKKGKIDVRGPLFVTVKAEIE 534
3 -75.3001b70_A mol:protein length:350 PHENYLALANYL-TRNA SYNTHETASE  ali model follow..  16  4..................................EALAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESE---FFNFDALNIPEHHPARDMWDTFWLGPLGEEVEGRLLLRTHTSPMQVRYM----VAHTPPFRIVVPGRVFRFEQ-TDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWW--PEGGKWLELGGAGMVHPKVFQAVDAYVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGVL........................................................................................................................................................................................ 350
4 -74.0002rhq_A mol:protein length:294 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  17  1..............MGSSSSGLVPRGSHMGTELMEKLNQQLAEETIDVTLPSRQISIGSKHPLTRTVEEIEDLFLGLGYEIVDGYEVEQDY------------------------------------------------------------------------YNFEALNLPKSHPARDMQDSFYI-------TDEILMRTHTSPVQARTMEK--RNGQGPVKIICPGKVYRRDS-DDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKLFGADREIRLRPSYFPFTEPSVEVDVSCNVCKHTGWIEILGAGMVHPNVLEMAGFDYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDVRFLEQFK........................................................................................................................................................................................... 281
5 -73.5003l4g_A mol:protein length:508 Phenylalanyl-tRNA synthetase alpha chain  ali model follow..  19  114....................RVDKSAADGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMTDNFIESS---FWNFDALFQPQQHPARDQHDTFFLYNWKLDEARKNLLRTHTTSASARALYRLAKKPFTPVKYFSIDRVFRNET-LDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFK--PAYNPYTEPSMEVFSY--HQGLKKWVEVGNSGVFRPEMLLPMGLNVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPLCRLDAEPRPPPTQEA......................................................................................................................................................................... 507
6 -71.1003pco_A mol:protein length:327 Phenylalanyl-tRNA synthetase, alpha subunit  ali model follow..  16  2................SHLAELVASAKAAISQA----------SDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDD---YHNFDALNIPGHHPARADHDTFWF-------DTTRLLRTQTSGVQIRTM----KAQQPPIRIIAPGRVYRND--YDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGK---NGKWLEVLGCGMVHPNVLRNVGIDYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK........................................................................................................................................................................................... 327
7 -70.1004p71_C mol:protein length:338 Phenylalanine--tRNA ligase alpha subunit  ali model follow..  16  2................ENLDALVSQALEAVRHT----------EDVNALEQIRVHYLGKKGELTQVMKTLGDLPAEERPKVGALINVAKEKDVLNARKTELEGAALAARLAAERIDVTLPGRGQLSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDD---YHNFEALNIPGHHPARAMHDTFYF-------NANMLLRTHTSPVQVRTM----ESQQPPIRIVCPGRVYRCDS--DLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCRVCKQTGWLEVMGCGMVHPNVLRMSNIDFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFR........................................................................................................................................................................................... 338
8 -48.5004tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase  ali model follow..  14  10...........................................PRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGFRELESELLSRRKKDLQQIYAEERE--------------------------NYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTE-------------LSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLSFIQMGSGCTRENLESIITDFLNHLGIDFKIV--GDSCMVYGDTLDVMH---------GDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................................................................................................ 278
9 -48.4004q6g_A mol:protein length:267 Pyrrolysine--tRNA ligase  ali model follow..  14  3..............................................................................LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPL----EYIERMGIDNDTELSKQIFRV---------DKNFCLRPMVAPNIFNYARKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLNFFQMGSGCTRENLESIITDFLNHLGIDFKIVG--DSCSVYGDTLDVMH---------GDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................................................................................................ 260
10 -48.2003cmq_A mol:protein length:415 Phenylalanyl-tRNA synthetase, mitochondrial  ali model follow..  14  34...................................................................................................................VLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDTTWQNFDSLLIPADHPSRKKGDNYYL-------NRTHMLRAHTSAHQWDLLHA------GLDAFLVVGDVYRRDQ-IDSQHYPIFHQLEAVRLAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINF----HGEWLEVLGCGVMEQQLVNSAGAQDRIWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCNQKVKFQPLSKYPAVI--NDISFWLPSENYAENDFYD--KVDLIDKFVHPKTHKTSHCYRITYRHMERTLSQREVRHIH--------------------QALQEAAVQL-LGVEGRF...................................................................... 415
11 -45.3005k1p_A mol:protein length:274 Pyrrolysine--tRNA ligase  ali model follow..  13  4..............................................................................LTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEY----IERMGIDNDTELSKQIFRV---------DKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLAFAQMGSGCTRENLESIITDFLNHLGIDFKIV--GDSCMVYGDTLDVMH---------GDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYY................................................................................................................................................................................................ 261
12 -40.6002e3c_A mol:protein length:291 Pyrrolysyl-tRNA synthetase  ali model follow..  14  13..............................................SHMASAPALTKSQTDRLEVLLNPKDEISLNSGFRELESELLSRRKKDLQQIYAEERENY--------------------------LGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTE-------------LSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIV--GDSCMVYGDTLDVM---------HGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSGSYY................................................................................................................................................................................................ 278
13 -31.6004bw9_A mol:protein length:291 PYRROLYSINE--TRNA LIGASE  ali model follow..  13  6...............................................................SGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTE-------------LSKQIFRVDKNFCLRPMLAPNLGNYLRKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLG---IDFKIVGDSCMVFGDTLDV--------MHGDLELSSAVVGPRPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSES.................................................................................................................................................................................................. 276
14 -31.4004cs2_A mol:protein length:274 PYRROLYSINE--TRNA LIGASE  ali model follow..  15  52..............................................................................................................................ERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERM-------------GIDNDTELSKQIFRVDKNFCLRPMLAPNLANYLRKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIV--GDSCMVFGDTLDVMH---------GDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRA-ARSESYYNGISTNL........................................................................................................................................................................................ 268
15 -30.2003qtc_A mol:protein length:290 Pyrrolysyl-tRNA synthetase  ali model follow..  13  5.................................................................LVPRGSHGASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTE-------------LSKQIFRVDKNFCLRPMLTPNLYNYLRKLDRALPDPIKIFEIGPCYRKES-DGKEHLEEFTMLVFWQMGSGCTRENLESIITDFLNHLGIDFKIVG-----------DSCMVFGDTLDVMHGDLELSSALVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRA....................................................................................................................................................................................................... 268
16 -22.0002zni_A mol:protein length:308 Pyrrolysyl-tRNA synthetase  ali model follow..  18  87...................................................................................................................................LLELEEKLAKALHQQGFVQVVTPTIITKSALAK-------------MTIGEDHPLFSQVFWLDGKKCLRPMLAPNLYTLWRELERLWDKPIRIFEIGTCYRKES-QGAQHLNEFTMLNLTELGTPLEHQRLEDMARWVLEAAGIREFELVTESSVV-----GDTVDV------MKGDLELASGAMGPHFLDEKWEIFDPWVGLGFGLERLLMIREGTQHVQSMARSLS.................................................................................................................................................................................................. 292
17 -13.8004h2w_A mol:protein length:346 Amino acid--[acyl-carrier-protein] ligase 1  ali model follow..  12  1...MGSSSSGLVPRGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKS----------------------LKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLS------------------------------------PADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVERWMVRAQAIARDLG---LTFRVDYASDPFFGRQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDA--CVAFGMDRLAVAMFH-AKVRDILGLQ................................................................................................................................................................................................... 327
18 -13.6003mey_A mol:protein length:346 Bll0957 protein  ali model follow..  12  1...MGSSSSGLVPRGSHMNIAVLPNSPDTAPQIADPLDHLADKLFHSMGSDGVYARTALYESIVERLAALITSHREAGTEALRFPPVMSRAQLEKS----------------------LKSFPNLLGCVCGLHGTEREINAAVSRFDAGGDWTTSLS------------------------------------PADLVLSPAACYPVYPIAASRGPLPKGGLRFDVAADCFRREPSKHLDRLQSFRMREYVCIGTPDDVERWMVRAQAIARDLG---LTFRVDYASDPFFGRQLKFELLIPLRSEEQPTACMSFNYHREHFGTTWGIQDA--CVAFGMDRLAVAMFH-AKVRDILGLQ................................................................................................................................................................................................... 327
19 -13.4003ica_A mol:protein length:213 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  14  1..............................................................................................................................SNADRRYKWQTVVSEQLVGAGFNEI----LNNSLTAGSYYEGLKSHPREMAVELMNPL--------SQELNCMRQTLLFGGLETLSHNLRRKHLSLYLFEWGKCYRFHAAKRTDETPEDDRLGIWICGEPTSVFELKAVVEQVLCRVGIETGAYTLKTA-DNDLYASAMEVKTRSGK------LLGTFGTVSTELIKRFEIEQPVYFAELLWDALM................................................................................................................................................................................................................... 213
20 -13.2003ig2_A mol:protein length:213 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  13  1..............................................................................................................................SNADKSNKLQNLVAEQLVGCGFNEI----LNNSLTRAAYYDGLESYPSKNLVMLLNPL--------SADLNCMRQTLLFGGLESIAHNANRKNADLKFFEFGNCYHFDAEKKNPEYSEDYHLGLWVTGENTSVYELKAYVENIFKRLGLDLHSLVVGNL-SDDIYSTALTVNTKGGK------RLATFGVVTKKMLKAFDVDNEVYYADLNWKELM................................................................................................................................................................................................................... 213
21 -13.0003l4g_B mol:protein length:589 Phenylalanyl-tRNA synthetase beta chain  ali model follow..  13  285.......................EAAEVVFPNGKSHTFPELAYRKEMVRADLINKKVG----IRETPENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYNTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGV-DISATKAVHISNPK---------TAEFQVARTTLLPGLLKTIAA-NRKMPLPLKLFEISDIVIKDSNTD-VGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVPKGGYVIKASEGPAFFPGRCAEIFARGQ------SVGKLGVLHPDVITKFELTMPCSSLEINIGPFL................................................................................................................................................................................................................... 589
22 -12.2003hri_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  12  43......................................................................................................................................LFDVFHSTARKFGFEEYDSPVLESEELYIRKAGEEITEQ------------MFNFITKGGHRVALRPEMTPSLARQLLAKGRSLLLPAKWYSIPQCWRYEA-ITRGRRREHYQWNMDIIGVKSVSSELVCAACTAMQSLGLSSKDVGVKINSRKILQTVVEVDKMEKLPREEVVAQLAAIGL-ESNVVDAITSTLSLKTIDEIAQRIGEEHEAVRELRDFIT-GFGDWVIFDASVVRGLAY-----------YTGIVFEGFDRDGNFRALCGGGRYDNLLTTYGSPTAVPCVFGDCVIVELLNEKKLLPELHHVVDDLVIPFDETMRPHAL-SILRRLRDAGRSADIVF-QAFNYADRIGALRAVLVAPDEWAVRVKMLREGAGREEGANERGIVL---PVDKI............... 449
23 -11.6003hrk_A mol:protein length:456 Histidyl-tRNA synthetase  ali model follow..  11  43......................................................................................................................................LFDVFHATAKTFGFEEYDAPVLESEELYIRKAGEEITEQ------------MFNFITKGGHRVALRPEMTPSLARLLLGKGRSLLLPAKWYSIPQCWRYEAI-TRGRRREHYQWNMDIVGVKSVSAELVCAACWAMRSLGLSSKDVGIKVNSRKVLQTVVEQAGVTSDKFAPVCVIVDKMEKIPREEVEAQLAVLGLEPTVVDAITTTLSLKSIDEIAQRVGEEHEAVKELRQFFEQVEAYGYGDWVLFDASVVRGLAEGFDREGKFRALCGGGRYDNLLTTYGSPTPIPCAFGDCVIVELLQEKRLLPDIPHVVDDVVIPFDESMRPHAL-AVLRRLRDAGRSADIKVVQAFNYADRVGAVRAVLVAPEEWEVQVKMLREGTGKEEGGAERGFAVPLDR................... 448
24 -11.3004g85_A mol:protein length:517 Histidine-tRNA ligase, cytoplasmic  ali model follow..  12........................................................MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPK---GTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLM-------------GKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYL---AMNKLTNIKRYHIAKVYRRDNAMTRGRYREFYQCDFDIAGNFDPMAECLKIMCEILSSLQIGDFLVKVNDR---FAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVAD----IGDYVQQHGGVSLVEQLLQGDLKLLFEYLTLFGIDDKISFDLSLARGLDYTGVIYEAVLLQTPAQAGEE---YDGLVGMFDPKGRKVPCVGLSIGVERILEALEEKIRTTETQVLVASAQKKLLEERL-KLVSELWDAGIKAELLYKKNLQYCEEAGIPLVAIIGEQELKIKLRSVTSREEVDVRREDLVEEIKRRTGQPL............... 517
25 -11.0003p8t_A mol:protein length:294 AsnS-like asparaginyl-tRNA synthetase related protein  ali model follow..  12  19....................................................................................................................................TKILDYMTKFFTDRGFKWLLPIMLSPI-----TDPLWPDPAGEGIRPAEVDVYGVRMRLTHSMILHKQLAIAMG----------------KIFVLSPNIRLESRRKDDHSYEFTQLDFEIE---AKMKDVMRLIEELIYGLFRKAEEVNIPREFYDREENGVWKNYDLILPYGYG--EVSSGGE---AKIRAAGLKEDSFGAGIGVERLVRFIVGAKHIAEV....................................................................................................................................................................................................... 281
26 -10.8004e51_A mol:protein length:467 Histidine--tRNA ligase  ali model follow..  10  46......................................................................................................................................FEATVKSLLRAYGYQNIRTPIVEHTPLFTRGI-------GEVTDIVEKEMYSFV-DALNGENLTLRPENTAAVVRAAIEHNMLYDGPKRLWYIGPMFRHER--QRGRYRQFHQVEALGFAGPDADAEIVMMCQRLWEDLGLTGIKLEINSLGLAEERAAHRVELIKYLEQHADKLDDDAQRRLYTNPLRVLDTKN---------PALQEIVRNAPKLIDFLGDV-HFEGLQRLLKANNVPFTINPRLVRGLDYNLTVFEWVTDKLGAQGT-----YDPLIEQLGGKPTAACGWAMGIERILELLKEEHLVPEQEGVDVYVVHQGDAAREQAFIVAERLRDTGLDVILSFKSQMKRADASGAAFAVIFGEDEVTNGTASVKP-------LRGTGDDGEKSVQQSVPVE-SLTEFLINAMV 453
27 -10.7001nnh_A mol:protein length:294 asparaginyl-tRNA synthetase-related peptide  ali model follow..  14  19....................................................................................................................................TKILEYMTDFFVKEGFKWLLPVIISPIT------PLWPDPAGEGMEPAEVEIYGVKMRLTHSMILHKQLAIAMG----------------KIFVLSPNIRLESRQKDDHAYEFTQLDFEVE---AKMEDIMRLIERLVYGLFRKAEEINIPREFYDREVDGFWRNYDLILPYGYG--EVASGGE---AKIRKAGLNEDSFGAGIGVERLVRFIVGAKHIAEV....................................................................................................................................................................................................... 281
28 -10.7004g84_A mol:protein length:464 Histidine--tRNA ligase, cytoplasmic  ali model follow..  34......................................................................................................................................VFDVIIRCFKRHGAEVIDTPVFELKETLM-------------GKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYL---AMNKLTNIKRYHIAKVYRRDNAMTRGRYREFYQCDFDIAGNFDPMAECLKIMCEILSSLQIGDFLVKVNDR---FAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVAD----IGDYVQQHGGVSLVEQLLQGDLKLLFEYLTLFGIDDKISFDLSLARGLDYTGVIYEAVLLQTPAQAGEE---YDGLVGMFDPKGRKVPCVGLSIGVERILEALEEKIRTTETQVLVASAQKKLLEERL-KLVSELWDAGIKAELLYKKNLQYCEEAGIPLVAIIGEQELKIKLRSVTSREEVDVRREDLVEEIKRRTGQPL............... 464
29 -10.6004up7_A mol:protein length:777 LYSINE--TRNA LIGASE  ali model follow..  11  144..................................................................................................PSMHYGLGDQETRFRKRYLDLIVNPESVKNFVLRTKVVKAVRKYLDDKGFLEVETPILNT------------IPGGATARPF------ITHHNQLDIQMYMRIAPELYLKELVVGGIN------RVYEIGRLFRNEG-IDQTHNPEFTTCE-AYADYNDIMKMTEELLGNMVKDITGGSTKLEIKDAYTELNNPIVQRSNFEQQAKDKAFLDAIEHAF--P----------PTGGWGLGIDRLAMLLADVDNIKEVILAATEEKGGKKVVKPKANKQQPVKEVLDGFQLEIRVGKIVEAGPHPNSEHLLALKVDV-GEEKPRSVVAGLAEHYKPEELLNQKATFVCNLKPSKLRGVASELAATSLDGTKVKFCHPSADAAIGAQVIEGKVTISAKKISIDVV-GKMNLALKGGLVRT-NDVPLIVKDTELTVTVDE-----IDGTV......... 770
30 -10.6003i7f_A mol:protein length:548 Aspartyl-tRNA synthetase  ali model follow..  13  248....................................................................................................................................SACCGLFREFLTSQKFVEIHTPKLIG------------CSSEGGSNIFEVKYFDRKAYLAQSPQLYKQMAIMGD----------------KVFEVGPVFRAENSNTRRHLTEFEGLDIEMEIVE-NYHECIDVMEKLFTFIILDKFPAAIRPFYTMPDIDDPNYSNSYDVFVRGQ--EITSGAQ---KRCIEKGVDPATLGCGIGLERITMLYLGIPNIRKVT...................................................................................................................................................................................................... 537
31 -10.6003net_A mol:protein length:465 Histidyl-tRNA synthetase  ali model follow..  32......................................................................................................................................LLDTIRRVYESYGFTPIETPAVERLEVLQQGDNIIYGLEPILPPNRQAEKDKSG--DTGSEARALKFDQTVPLAAYIARHLNDLTFPFARYQMDVVFRGER--KDGRFRQFRQCDIDVVGRELYDAQMPAIITEIFEAVNIGDFV-----------------------------IRINNRKVLTGFF-----------SLNISETQIKSCISIIDNLEKIVKLELEKEGINPEQTQKIIDFKIDGSVDDVLDKLKHLSQTLPESEQFNLGVS---------ELETVITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTLIGHEAGGRYEELVGTFIGEGISIGLTRLISRLLKAGILNTLVVNMQDELMPTYLKVSQQLRQAGLNVINFEKRQLGKQFQAADKQGIRFCVIIGADE 432
32 -10.3005e3i_A mol:protein length:438 Histidine--tRNA ligase  ali model follow..  10  26......................................................................................................................................LEQHLASLMDAYGYQQIRLPIVEQTGLFKRAI-------GDATDIVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEK--QKGRYRQFHQVETFGVATPDIDAELIMLTARLWKRMGVDHVQLELNTLGETDERTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSK---------IESTQKILENAPKLHDFLKED-HFQQLQDYLTAAGIKFVINQKLVRGLDYNKTVFEWTTTALGSQGT---GLVGQLKGKADQSVPAV--------ERLLLLLEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNI-SQMKKADQAGAVYAIILGEREWELAVKELATAEQSQVALAELVPFLIEKFTK................. 432
33 -10.1003od1_A mol:protein length:400 ATP phosphoribosyltransferase regulatory subunit  ali model follow..  11  28....................................................................................................................................KNICDQMTEEINLWGYDMIETPTLE-------YYETVGVVSAILDQQL------FKLLDQQGNTLVLRPDMTAPIARLVASSLKDRAYPLRLAYQSNVYRAQQN-EGGKPAEFEQLGVELIGDGTASADVIALMIAALKRAGLSEFK-----------------------------VAIGHVGYVNALL-----------DVVGNEQRADRLRRFLYEKNYVGYREH--VKSLNLSTIDKSRLMNLLSLRGGRAAIEEARGLIQTEKGKTALAEMTKLYEVLESY-------------SEYVKFDLTLVLHMSYYTGVVFEGYGNR-CSGGRYDELLSKFHRPGFGVRIDLLVEALNGEIISNGHCILFSNERRFEAIELARKKRANGEAVVQDLAGVTDVDAMSSNYQDVIYCIGTAGRG 396
34 -10.1001wu7_A mol:protein length:434 Histidyl-tRNA synthetase  ali model follow..  26......................................................................................................................................IFKTAEEAAEAFGFRRIDFPSLEYLDLYRIKSGEELLQQ------------TYSFVDKGGREVTLIPEATPSTVRMVTS-RKDLQRPLRWYSFPKVWRYEE--QAGRYREHYQFNADIFGSDSPEADVIALASSILDRLGLQDIRINSRKIMEEIIGGMTSSDPFSVFSIIDRYHKISREEF---DQLRSAGIGEDGVS----IADLCSGTRGIDEMARITGKSSEEIARMAAASYGVKNVRYDFSIVRGLSYTGIVFEAYDRSGQFRAILGGGRYDNLASLMSGESVPAVGFGMGDAVISLLLKRENVQIPREKKSVYICRVGKINSSIMNEYSRKLRERGMNVTVGLSAQLKYASAIGADFAVIFGERDLEVTIRNMYTGSQENVGLDSVVEHLISQATLE................ 428
35 -9.7501qe0_A mol:protein length:420 Histidine--tRNA ligase  ali model follow..  22......................................................................................................................................IENQLDELMTFYNYKEIRTPIFESTDLFA---RGVGDSTDVVQKEM------YTFKDKGDRSITLRPEGTAAVVRSYHKMQGNPNQPIKLYYNGPMFRYER--QKGRYRQFNQVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTDPMRILDCK---------VDRDKEAIKTAPRITDFLNEE-YYEQVKAYLDDLGIPYTEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLYNGLLELLDGPSETGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAV-KLLNHLRHNGIKADKDY-GQMKQADRLGAKFTIVIGDQELEIDVKNMTTGESETIELDALVEYF....................... 418
36 -9.6203rac_A mol:protein length:373 Histidine-tRNA ligase  ali model follow..  10  3..............................................................................................AMNGTRSAWGARAWEAVRGFADRPPGMQDGYPDFAKRRRAVETRLLSFVEDAGYEPVTSGLFEYVDTLLRARSPESSRD------------WIRLFDGGGDAVALRPEMTPSIARMAAPRVAAGRTPIRWCYCERVYRRTDSWASGKAAESTQVGIERIGEEASVMDVLRLLHEASAAAGVRHHR-----------------------------IVVSHARLVPRLL-----------ALGISASLSRAFLACLTSGNYV------------RELWQLHAAKDVDLLANLLTWSPAERDAAKRSREASDRELEALLRDAVDPRAAADVRDAWRYLCRLAEALHDSGLASDVV-------------------------TFDLALHRELDYYTGLVEMFAPGVGAPIAQGGRYDELLAQFGAGAPAVGFAFEERVMAVLEAQEE................. 368
37 -9.3905xil_A mol:protein length:512 Putative prolyl-tRNA synthetase  ali model follow..  47....................................................................................................................................KCVQRFLGGKIEKLGVEDCYFPMFVSR-------SCLEREKDHIEGFAPEVAWVTR-DTELEQPVAVRTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEHPTPFIRTREFLWQEGHCAECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQ-NSWGLSTRVIGVMIMVHGDNRGM----------------------VMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESELCEGGVRARCDLRDNYS------------FNHWEVKGVPGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHAQMARAKETMETHRVRVTEWTEFVPTLNR............................ 429
38 -9.3205xix_A mol:protein length:472 Asparagine--tRNA ligase, cytoplasmic  ali model follow..  13  168....................................................................................................................................SMVTRCFRDHFFDRGYYEVTPPTLVQ------------TQVEGGATLFKLDYFGEEAFLTQSSQLYLETCLPALG---------------DVFCIAQSYRAEQSRTRRHLAEYTHVEAECP---LTFDDLLNRLEDLVCDV--GSIVHELNPNFQPPKRPFKRMNYSDAIVWLKE--EIVGGSM---AGYKREGIDPTPYGYGLGLERFLTWILNRYHIRDVC...................................................................................................................................................................................................... 455
39 -9.1004lns_A mol:protein length:351 Asparagine synthetase a  ali model follow..  13  8...............................................................................................................................SYVLLQEQILTVKRSFSEALEKELNLVEVRAPILFRVGDGT--SGFEKAVQVPVKAIPNASFEVVHSLAKWKRRTLANYKFAPGH----------GLYTHMTALRVDDVLDNIHSVVVDQWD-VMKDDQRNLAFLKEVVCKVYAAIRKTELAVCEKYKQKPILPETIQFDILLYNPTLDDSLEVSSMGI-AEALRHQISLT-QTVGGGIGQSRMVMFMLRKKHIGEVQCS.................................................................................................................................................................................................... 338
40 -9.0702xti_A mol:protein length:437 ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, PUTATIVE  ali model follow..  13  138....................................................................................................................................AAATRAMREHFYNAGYVEVAPPTLVQ------------TQVEGGSTLFNLDYFGEQSFLTQSSQLYLETCIPTLG---------------DVFCIAQSYRAEKSRTRRHLAEYAHVEAECP---ITLDDLMEKIEELVCDTLLNRFPSEIKAFYMQRDAKDNTLTESVDLLMPG---EIVGGSM---KAFKNVEIDPKPYGYGLGLERFICWLTNTNHIRDVC...................................................................................................................................................................................................... 426
41 -9.0503m4p_A mol:protein length:456 Asparaginyl-tRNA synthetase, putative  ali model follow..  16  160....................................................................................................................................SEIQWYFRKYYHDNHFTEIQPPTIVK------------TQCEGGSTLFKLQYFNEPAYLTQSSQLYLESVIASLG---------------KSFCMLSSYRAEQSRTVRHLAEYLHLEAELP---ISFEDLLNHLEDLVCTV-FKRMTYHFPSKMKAFYMSKVPGHTESVDLLMPGVGEIVGGSM---GAYKANGLNPDPYGYGLGVERLVMWLLGEDHIRKVC...................................................................................................................................................................................................... 445
42 -9.0101n9w_A mol:protein length:422 aspartyl-tRNA synthetase 2  ali model follow..  14  129....................................................................................................................................AALVRGFRRYLDRQDFTEIFTPKVVRA------------GAEGGSGLFGVDYFEKRAYLAQSPQLYKQIMVGVFE---------------RVYEVAPVWRMEEHHTSRHLNEYLSLD-VEMGFIADEEDLMRLEEALLAEMLEEALNTRYPRSVRPFYTYPEEDGTTRSFDLLFRGLEITSGGQ---ESLKAKGMDPEAFGFAIGAERLTQKLLGLPNVRYAR...................................................................................................................................................................................................... 411

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Osterman A, Overbeek R, Godzik A. Automatic detection of subsystem/pathway variants in genome analysis. Bioinformatics. 2005 Jun 1;21 Suppl 1:i478-i486.