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Query: 5ynl_A mol:protein length:362 Arginase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSSGLVPRGSGMKETAAAKFERQHMDSPDLGTDDDDKMSPATSPFLATPRTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSDTPDPDIGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEACLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIGLRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDPSVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGALASVAQTVDVGRSLVRCALGETLLLast
1 -99.1005ynl_A mol:protein length:362 Arginase  ali model  100  1MSSGLVPRGSGMKETAAAKFERQHMDSPDLGTDDDDKMSPATSPFLATPRTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSDTPDPDIGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEACLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIGLRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDPSVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGALASVAQTVDVGRSLVRCALGETLL 356
2 -86.9001pq3_A mol:protein length:306 Arginase II, mitochondrial precursor  ali model follow..  45  1.................................................HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYN---NLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEATTANLAVDVIASSFGQTR. 304
3 -86.7001wva_A mol:protein length:322 Arginase 1  ali model follow..  47  1............................................MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQI----VKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVRTVNTAVAITLACFGLAR. 308
4 -86.4001d3v_A mol:protein length:323 PROTEIN (ARGINASE)  ali model follow..  45  1............................................MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVP----NDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVRTVNTAVALTLSCFGTKR. 308
5 -85.7001t5f_A mol:protein length:314 Arginase 1  ali model follow..  44  1.................................................KPIEIIGAPFSKGCPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVP----NDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLAVIWVDAHTDINTPLTTSSGNLAGQPVAFLLKELKGKFPDVPGFSWVTPAISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVRTVNTAVALTLSAFGTKR. 303
6 -81.4002eiv_A mol:protein length:291 Arginase  ali model follow..  35  2.................................................ERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEIRAA----ALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAAR-GRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGH------PRLTEVFRAVDPKDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHL---QGLPLHVSLDADVLDPTLAPGVGTPVPGGLTYREAHLLMEILAESGRVQSLDLVEVNPILDERN---RTAEMLVGLALSLLGKRIF 291
7 -79.8001cev_A mol:protein length:299 PROTEIN (ARGINASE)  ali model follow..  34  2.................................................KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGD--IPIGKAERLHEQGDSRLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGH---PALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYL-KERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERN---KTASVAVALMGSLFGEKLM 299
8 -79.4006dkt_A mol:protein length:296 Arginase  ali model follow..  34  2................................................DKTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINREKIKNDEE-----LKNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKHYDNLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGIGH---ESLVNLEGYAPKIKPENVVIIGARSLDEGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYL--SACDGVHLSLDLDGLDPNDAPGVGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPILDHKN---KTGKTAVELVESLLGKKLL 296
9 -79.4004q3p_A mol:protein length:385 Arginase  ali model follow..  34  2.................GSSSSGLVPRGSHMMLKSVATPYQDEKPKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSKSTPVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCR. 352
10 -77.3004ity_A mol:protein length:330 Arginase  ali model follow..  48  3............................................GSGMAKKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFVVEARKASDNGDRIGR-VKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPEC--FSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVDTISVGCAIARCMMGETLL 315
11 -73.1003nio_A mol:protein length:319 Guanidinobutyrase  ali model follow..  21  2.............DKNLHQPLGGNEMPRFGGIATMMRLPHVQSPAELDALDAAFVGVPLDIGSLRSGTRFGPREIRAESVMIRPYNMATGAA-----PFDSLNVADIGDVAINTFN----LLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHMFG-EKIAHGTTFRRAVEED---------------LLDCDRVVQIGLRAQTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKV---GGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGC-QGLDLIGCDLVEVSPPYDTTGNTSLGANLLYEMLCVLPGVV.. 317
12 -71.2001gq6_A mol:protein length:313 PROCLAVAMINATE AMIDINO HYDROLASE  ali model follow..  18  2..................ERIDSHVSPRYAQIPTFMRLPHDP---QPRGYDVVVIGAPYDGGSYRPGARFGPQAIRSESGLIHGVGIDRGPG-----TFDLINCVDAGDINLTPFD----MNIAIDTAQSHLSGLLKANAAFLMIGGDHSLTVAALRAVAEQHGPLAVVHLDAHSDTNPAFYG-GRYHHGTPFRHGIDEK---------------LIDPAAMVQIGIRGHKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKV---GQRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCV-GDLKPVGFDVMEVSPLYDHGGITSLATEIGAELLYQYARAH.. 309
13 -71.0004g3h_A mol:protein length:330 Arginase (RocF)  ali model follow..  18  1...................................................MILVGLEAELGASKRGTDKGVRRLREALSATHGDVIK---GMQTITQERCVLYKEFRYAK----NFEDYYLFCKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMSELEKGGLEIDPKCLVYFGVRSTEQSERDVIRELQIPLFSVDAIRE-NMQEVVQKTKESL--KAVDIIYLSLDLDIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESDRLKAVEVTEYNPTVSIKHNNE-EEKQVLEILDLIINSCK. 310
14 -70.4003nip_A mol:protein length:326 3-guanidinopropionase  ali model follow..  21  2.............SNDHPQPLDAAEIPRFAGIPTFMRLPAFT---DPAALQVGLIGVPWDGGTNRAGARHGPREVRNLSSLMRKVHHVSRIA-----PYDLVRVGDLGDAPVNPID----LLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGR-ERPLGMVHFDAHSDTNDRYFGDNPYTHGTPFRRAIEEG---------------LLDPLRTVQIGIRGSSPDDDAFARECGIRVIHMEEFVELGVEATLAEARRVV---GAGPTYVSFDVDVLDPAFAPGTGTPEIGGMTSLQAQQLVRGL-RGLDLVGADVVEVSPPFDVGG---ATALVGATMMFELLC.... 308
15 -70.2003mmr_A mol:protein length:413 Arginase  ali model follow..  32  8.......................................LVPRGSHMASKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNINYEENNVISTNDKYKNNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYF-EWSENLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHTGKLCLELIARVLGYDIV 407
16 -69.9003pzl_A mol:protein length:313 Agmatine ureohydrolase  ali model follow..  22  5....................GNGREKDHASELRSIFSLKKIADVNGYEEAKYVVFGIPFDNTSYRRGSKYAPDSIRGAYVNLESYEYSYGID------LLASGMADLGDMEES-----EDVEYVIDTVESVVSAVMSDGKIPIMLGGEHSITVGAVRALPK---DVDLVIVDAHSDFRSSYMG-NKYNHACVTRRALDL-----------------LGEGRITSIGIRSVSREEFEDPDFRKVSFISSFDVKKNGIDKYIEEV-----DRKSRRVYISVDMDGIDPAYAPAVGTPEPFGLADTDVRRLIERLSY--KAVGFDIVEFSPLYDNGNTSMLAAKLLQVFIASREKYY.. 301
17 -69.4001wog_A mol:protein length:305 agmatinase  ali model follow..  20  2.....................SGPAHLPYGGIPTFARAPLVQP-DGDWQADVAALGVPFDIAGFRPGARFAPRALREASLRSVPPFTGLD----GKTRLQGVTFADAGDVILPSLE----PQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFAD-VPDLHVVQLDAHLDFTDTRND-TKWSNSSPFRRACEAL----------------PNLVHITTVGLRGLDPEAVAAARARGHTIIPMDDVTADLAGVLAQLP-------RGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELMARLVMETLCEVFDHVL. 305
18 -69.1004dz4_A mol:protein length:324 Agmatinase  ali model follow..  20  18.................PSVYGSSIENTYAGVLSFMRRNYTR---DLDGVDVVVSGVPLDLATFRSGARLGPSAVRAASVQLA----ELNPYPWGFDPFDDLAVIDYGDCWFDAHH----PLSIKPAIVEHARTILQSDARMLTLGGDHYITYPLLIAHAQKYGPLSLIHFDAHCDTWADDAP-DSLNHGTMFYKAVKDG---------------LIDPKASVQVGIRTWNDDY------LGINVLDAAWVHEHGARATLERIESIV---GGRPAYLTFDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGL-GGVNLIGADVVEVAPAYDQSEITAAAAHVACDLLCLWRQRK.. 320
19 -67.5003m1r_A mol:protein length:322 Formimidoylglutamase  ali model follow..  19  18...........................KDRDVTKMSDLI--ATWDGQDIKGPALIGVPLSKSISHSGASFAPGTIRQALKHSSAYSAELGEH------VVSELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSD--HPDWVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDG--GPTNGTPFRRLLDEE---------------IIEGQHLIQLGIREFSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQ-DKTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRD---MTSRAAAHVLLHALK.... 314
20 -67.1004rhm_A mol:protein length:351 Arginase  ali model follow..  18  1........................MGSSSSGLVPRGSHMF----------SKFLMNVKGVTPGSDWANRLGPVALFGYGAGMPRRAPLLDFFPRDCDHYAELTIHDKGPIECPPETVMPTSDEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFPDIVIVHFDAHPDVSD---------PRSPLRVLLDKGLL-----------------KGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKGLFCIRDIR-------NDYPVFISIDADVLDPAFAPAVDSPVAGGLSTRDLLHIMNGI-RGPKVVGIDVYGYNPDLDVYRKVGLTAIALSKIIKEGILKAY. 314
21 -67.0003lhl_A mol:protein length:287 Putative agmatinase  ali model follow..  19  3............................................LNYEESNLIVFGVGFDGTSNRPGARFASSSMRKEFYGLETYSPFLDLD------LEDYNICDYGDLEISVGS----TEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNN-SKNSHATVIKRIWD-----------------IVGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGID------TFENIVNML---NGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKSNINIVGCDIVELSPDYDTTGVSTIACKILRELCLIISDKI.. 278
22 -65.8002a0m_A mol:protein length:316 ARGINASE SUPERFAMILY PROTEIN  ali model follow..  18  4..........................AARTDDPRLLSLFSAQ---REEDADIVIIGFPYDEGGGRAGAKKGPAAFRFFLQRLGSVN-----NLELNVDASHLKLYDAGDITAS------TLEEAHEKLESKVFTVLARGAFPFVIGGGNDQSAPNGRAMLRAFGDVGVINVDSHLDVRPPLQD-GRVHSGTPFRQLLEES---------------SFSGKRFVEFACQGSGALHAQYVRDHQGHLMWLSEVRKKGAVAALEDAFGLTG----KNTFFSFDVDSLKSSDMPGVSCPAAVGLSAQEAFDMCFLAGKTPTVMMMDMSELNPLVEEYRSPRVAVYMFYHFVLGFATRP.. 304
23 -65.1004rhi_A mol:protein length:351 Arginase  ali model follow..  17  1........................MGSSSSGLVPRGSHMFSKF------LMNVKGVTPRG---SDWANRLGPVALFGYGAGMPRRAPLLDFFPRDCDHYAELTIHDKGPIECPPETVMPTSDEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFPDIVIVHFSARPSVSD---------PRSPLRVLLDKGLL-----------------KGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKGLFCIRDIR-------NDYPVFISIDASVLDPAFAPAVDSPVAGGLSTRDLLHIMNGI-RGPKVVGIDVYGYNPDLDRKDNVGLTAIALSKIIKEGILKAY. 314
24 -54.1001xfk_A mol:protein length:336 Formimidoylglutamase  ali model follow..  13  12..............QGRHDPEDGQAGRRVHHIACPIQVGELAN----QEPGVALIGFECDAGKGRTGAKHAPSLIKQALANLAWHH--------------PIPIYDLGNIRCEG----DELEQAQQECAQVIQQALPHA-RAIVLGGGHEIAWATFQGLAQHFPRIGIINFDAHFDLRTFESELAPVSSGTPFNQIHHFCQQQG-------------WDFHYACLGVSRATPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFI--DDCDYLYLTIDLDVFPAASAPGVSAPAARGVSLEALAPYFDRILHKNKLMIADIAEYNPSFDIDQ---HTARLAARLCWDIAN.... 324

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.