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Query: 3a5y_A mol:protein length:345 Putative lysyl-tRNA synthetase, from PDB1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRALast
1 -71.400PF00152.20; SYDND_NEIMB/118-567; tRNA synthetases class II (D, K and N)  ali follow..  20  1....SENVRLTNRVIDL----RRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGA-----RDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFLNEDEIMDITEGMAKQVFKDGDFPRMPYSEAMFYY-GAEFSRKEIDEYTKFVGIYGAKGLAYIKVNDVSNLSNGEDSGLQSPIVKVAVHHPFTAPKEGHEDLMVSDPANCLARAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKI----SPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDVIAFPKTQ. 450
2 -12.700PF01409.20; SYFA_BACHD/92-341; tRNA synthetases class II core domain (F)  ali follow..  16  20.................................TATITEVEDLFIGLGFSVAEGPQIETD-----NFEALNLPKDHPARDMQDSFYFSPVQARTMEKYKGKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVR--MSDLKGVLQAFAKSFFGEERSIR-----------------------------------------LRPSFFPFTEPSV---------EVDVSCGICHGDGCRVCKQTGWIEILGAGM-----------------------------------VHPRVLEMSGFNPNEYSGFGMGVERLSMLKYGIDDIRHF........ 239
3 -11.000PF13393.6; G2IXI8_PSEUL/10-315; Histidyl-tRNA synthetase  ali follow..  12  7...........................ATARQVESAKAAMLELFRTAGYELVLPPLIEDALVSEGDSALDIKTFKLDDHLSGRQLGLRADITPQVARIDAHLLSRLCYAGSVVHARPSGLMSSREPLQVG----------------ELYGYAGIEADLEIIELMLATLRQVGVDKLRLDVGHIAIF---RGLAAAAGLAAEDTRELFGALQSKDIATVRELVAEVAEPYKSAFLALPELYGPRQVLDKARTRLPSLPEVELGLMQLTAIANAQVELSFDLAELRGDFYHTGLMFAAYAPGWSEAL-PATGFSLDLRDL..................... 306
4 -7.420PF16761.5; R4XBL7_TAPDE/70-138; Transcription-silencing protein, cryptic loci regulator Clr2  ali follow..  12  2................................................................................................................................................................................................................................ALADFPENYTLLEHNKYQGEGKKPRTDMYLYGHPSGSRFRSINEFIPHMLWLAKDKQHSPKT..................................................... 63
5 -6.910PF02091.15; SYGA_PELCD/3-280; Glycyl-tRNA synthetase alpha subunit  ali follow..  13  2.................................QELILALQNYWAKQGCIIQQPYDMEKGAG--------------------------TFNPATFLRVLGPEPWNVAYVEPSRRPT--DGRYGENPNRLQHYYQFQVVTNIQELYLDSLKSFGISPSRHDIRFVE---------------------------------------------DDWESPTLGAWGLG-------------------------WEVWLDGMEITQ-YFQQVGGIDL----------------KPVSAE----------------ITYGCERIAMYLQGVDNVYDLEWIDGIK. 182
6 -6.820PF14945.6; G5AUM4_HETGA/16-134; Normal lung function maintenance, Low in Lung Cancer 1 protein  ali follow..  14  1................................................................................................................................................................................................................................LVAQDEIWRYLLKAESEARKNWAQNWGF------LTTSLEELIQGEEPHTPKPKVELPEHFRIRPVTPIEKYIKVLPSPPVPQTTQGLIGLEHDNMIRSCKGAYARGLGWP.... 116
7 -5.850PF14881.6; C5FUZ2_ARTOC/120-304; Tubulin domain  ali follow..  10  2.......................................................................................................................................................................................................................PELTPETVRYWSDFPRSIQQINEYDLGSQ--LVPFEDWSRGQSLFSELDGEHDLLDRDLRPFAE--------------ECDQLKGIQIFSGTDDAWGGFAASYVDRLKDEYGGKSIWTWAINGS 115
8 -5.510PF08331.10; D5ANY6_RHOCB/54-130; Domain of unknown function (DUF1730 topsan)  ali follow..  14  1.......................................................................................RGNP-----AALWPEARSVILLAESYEVDPREATRQPGHGAISVYAQGKDYHDLVRRLKRLGRWLIENSPCEIKVFVDT............................................................................................................................................................................. 77
9 -5.360PF11169.8; B7VIL4_VIBTL/9-113; Protein of unknown function (DUF2956 topsan)  ali follow..  14  3...................................................................................................................................................................................................................................ESQQEALKIAKATQKPAQTKEQTKLIAQGIE--KGIALYKKQQKERSRQADKARKRVQKEKQTQQTNLDEENNVDTIVETTSNHANKLPWLLLIAS................ 96
10 -5.300PF11339.8; Q1LQX6_CUPMC/45-624; Protein of unknown function (DUF3141 topsan)  ali follow..  221FEKLDPANTFWSKLYNVYAKADTEGPRFLEFERGEIDWIVQNLFVGNHLTNVRSPVIVFASWGDNITPPQQALNWIPDLYANVDEIVANDQTIVYCLHPSIGHLGIFVSGSVAN---------------KEHSELFCALDLIDVLPPGLYEAKIDDIAPGTSHKDLIEGRYMVRFERRTIDDILALDDGRDDELPFQVVRRVAEINQHLYDTFASPFLRAMSNESMAEHPTRLSAMAPAVREARQPVSPDNPFLAMQTAIDLYRDMRDAWQEQA-LPALFGMKVDTERAESPAVSALRTEVAEL-----RRREALSRI..................... 580

FFAS is supported by the NIH grant R01-GM087218-01
1 3 3 2 1 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Berman HM, Burley SK, Chiu W, Sali A, Adzhubei A, Bourne PE, Bryant SH,Dunbrack RL Jr, Fidelis K, Frank J, Godzik A, Henrick K, Joachimiak A, HeymannB, Jones D, Markley JL, Moult J, Montelione GT, Orengo C, Rossmann MG, Rost B,Saibil H, Schwede T, Standley DM, Westbrook JD. Outcome of a workshop on archiving structural models of biological macromolecules. Structure. 2006 Aug;14(8):1211-7.