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Query: 4tqd_A mol:protein length:291 Pyrrolysine--tRNA ligase, from PDB1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGSSSSGLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLSFIQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNLLast
1 -52.000PF01409.20; SYFA_BACHD/92-341; tRNA synthetases class II core domain (F)  ali follow..  14  1..........TIDVTLPGRPVLKGGAHPLTATITEVEDLFIGLG--FSVAEGPQIETDYYNFEALNLPKDHP-----ARDMQDSFY-----------------------------------FTDELLLRTQTSPVQARTMEKYKG--KGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVRMSDLKGVLQAFAKSFFGESIRLRPSFFPFTEPSVEVTGWIEILGAGMVHPRVLEMSGFNPNGFAFGMGVERLSMLKYGIDDIRHFYTNDRRF....... 246
2 -30.200PF13393.6; G2IXI8_PSEUL/10-315; Histidyl-tRNA synthetase  ali follow..  11  1.............................................................IADILPATARQ-VESAKAAMLELFRTAGYELVLPPLIEYADALSEGDSALDIKTFKLDDHLSRQLGLRADITPQVARIDAHLLSNRTGVTRLCYAGSVVHARPSGLMSSREPLQVGAELYGYAGIEADLEELMLATLRQVGVDKLR------------------LDVGHIAIFR-GLAAAAGLAAEDTR------FGALQSKDIATVRELVAE........... 193
3 -24.800PF00152.20; SYDND_NEIMB/118-567; tRNA synthetases class II (D, K and N)  ali follow..  13  1...................................................SENVRLTNRVIDLRRPVRNLRLRYQVAMGVRRYLDAQGFIDIETPML-----TRSTPEGARDYLVPSRVHPGEFFALP------QSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFLN--EDEIMDITEGMAKQV-----------------FKDALNVDLGDFPRMPYSEAMFYYGSDKPDMRINLKFTELTDLMKTEE................... 187
4 -22.600PF17759.1; A0A0C5VP95_9GAMM/474-682; Phenylalanyl tRNA synthetase beta chain CLM domain  ali follow..  15  10.................................................................LEMPALKEADISHRVIKNSLVSLGMQEIVTYSFLDRKTQSLFESELEPVALANPISEDLAV-MRTSLIPNLVKTLSYNINRQQERIRLFETGLSFINTN---DGLLQNQKLAGLIYGEEVDFYDLKSIVETVLALAPGKQCVFEPGQIEFGQTAFIRCDDQIIGYLGLVHPSIRKTLGLKKGVFVFELDM.............................. 208
5 -11.600PF02091.15; SYGA_PELCD/3-280; Glycyl-tRNA synthetase alpha subunit  ali follow..  12  1.........................................................................FQELILALQNYWAKQGCIIQQPYDME--------------------------------KGAGTFNPATFLRVLGPEPWNVAYVEPSRRPT--DGRYGENPNRLQHYYQFQVVM-TNIQELYLDSLKSFGIEDDWESPTLGAWGLGWEVWLDGMEITQFTYF--QQVGGIDLKPVSAEITYGCERIAMYLQGVDNVYDL.............. 175
6 -7.320PF00587.25; SYT_ECOLI/318-529; tRNA synthetase class II core domain (G, H, P, S and T)  ali follow..  19  7..........................................................................................................................NREYCIKPMNCPGHVQIFNQGLKSYRDPLRMAEFGSCHRNEPSGSMRVRGFTQDDAHIFCTEEQIRDCIRLVYDMYSTFGFEKIVVKLSTRP....................................................................... 107
7 -7.010PF02269.16; SUPT3_HUMAN/24-116; Transcription initiation factor IID, 18kD subunit  ali follow..  10  2...........................................................................SFATELQSMMYSLG--DARRPLHETAVLVED--------------------VVHTQLINLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGIDE................................................................................................ 93
8 -6.170PF09749.9; B2AA01_PODAN/50-293; Uncharacterised conserved protein  ali follow..  12  44.............................................................IEWHPPPEFKRMLSGLIYSVRSQI----------RKIDPEVEITSFLESDLGVPLPLHISLSRPLNLSTFQKDQFLSDLQKILAGDQPFEIRLGRVEWHFTSE----SGRAFLVLRVVCPSRNNELVYLLSKINELANIYGQPQLYSWAS----AAEGKDVADAFHFSIAWCLGKPSDHLERITKEVFAKPEIRTVIGMGKLTIHSIKVKIGNVVT........ 241
9 -5.580PF10275.9; Q7SI56_NEUCR/243-485; Peptidase C65 Otubain  ali follow..  2.......................GDKLPSTAITEEYAKADPVYVQKTRSLPAVYSHYRFGYFETLIKLGNKAQVDGERERLESLMVFVDFVEETDELLKRISDKLNVPEEAMSEVMHAFTDAEKSNAIIYHLRLLASSWLKENRGS-------------HEAFITTDESVEKFCQRVIEVPNIEIDQLGLQALVSILLKPVGFVLRV.............................................................................. 198
10 -5.230PF09736.9; E2BWY8_HARSA/413-553; Pre-mRNA-splicing factor of RES complex  ali follow..  14  3..............................................VRDKSGRKRNFEAE-----AAEERQREAQQREMNEKYTKWGKGLKQVE----DREEQLKSDLHEMNKPLARYADDADLDKQLREQEGDPMLAYIKEKRTKEGKAPNRFGIKPGHRWDGVDRSNGYE................................................................................................................. 133

FFAS is supported by the NIH grant R01-GM087218-01
1 2 7 4 5 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sasin JM, Godzik A, Bujnicki JM. SURF'S UP! - protein classification by surface comparisons. J Biosci. 2007 Jan;32(1):97-100.