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Query: 6aqh_A mol:protein length:508 Lysine--tRNA ligase, from PDB1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAMTPPESVDPDLPEQFRIRQAKRADLLAQGRQPYPVDVPRTHTLLEIRQAYPDLPVDARTGEIVGVTGRVVFARNSGKLCFATLQEGDGTQLQAMISLAEVGQEALDNWKTYVDIGDIVFVHGEVITSKRGELSVLADSWQMAAKALRPLPVAHKEMSEESRVRQRYVDLIVRDQARKVARQRIAVMRAIRSALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDTELYLRIAPELFLKRCLVGGFERVFELNRVFRNEGADSTHSPEFVMLETYQAYGTYDDSAVVTRELIQEVADEAIGTRQVPLPDGTVYDLDGEWESIQMYPSLSEALGEEITPDTPAETLWAIADRLGLDIPRDRGYGHGKLVEELWEHTVGAKLWAPTFVKDFPVETTPLTRSHRSIPGVTEKWDLYVRRIELATGYSELTDPIIQRERFEAQARAAAAGDDEAMALDEDFLAALEYGMPPSTGTGMGIDRLMMTLTGLSIRETVLFPIVKPRLast
1 -70.800PF00152.20; SYDND_NEIMB/118-567; tRNA synthetases class II (D, K and N)  ali follow..  20  1..............................................................................................................................................................SENVRLTNRVIDL-RRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFRDEDLRADRQPEFTQIDLETSFLNEDEIMDITEGMAKQVFKDALNVDLG------------DFPRMPYSEAMFYY--TDLMKTEEFKVFRGAADMKGGRVVALRVPNGAEFSRKEIDEYTADRYVAVHHPFTAPKEGHEDLMVSDPANCLARAYDMVLNGWEIGGGSIRIHRADVQEKVFAALKI----SPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGASIRDVIAFPKTQ.. 450
2 -11.700PF01409.20; SYFA_BACHD/92-341; tRNA synthetases class II core domain (F)  ali follow..  19  20........................................................................................................................................................................................TATITEVEDLFIGLGFSVAEGPQIETDYYNFEALNLPKDHPAFTDELLLRTQTSPVQARTMEKGPIKIICPGKVFRRDDDDATHSHQFMQIEGLYVDHGVR--MSDLKGVLQAFAKSFFGEERSIRLRPSFFPFTEPSVEVDVSCGICHGDGCRVCKQTG------------------------------WIEILGAGMVHPRVL--------------------------------------------------------------EMSGFNPNEYSGF--------AFGMGVERLSMLKYG--IDDIRHF...... 239
3 -9.060PF13393.6; G2IXI8_PSEUL/10-315; Histidyl-tRNA synthetase  ali follow..  14  1............................................................................................................................................................................IADILPATARQVESAKAAMLELFRTAGYELVLPPLIEEGDSALDIKTFKLDDHLSGRQLGLRADITPQVARIDAHLLSRLCYAGSVVHARPSGLMSSREPLQVELYGYAGIEADIIELMLATLRQVGVD---------------KLRLDVGHIAIFRGLAAAAGLAAEDTRELFGALQSKDIATVR----------ELVAEVAEPYKS--------------AFLALPELYGPRQVLDKARTRLPSLPEVELGLMQLTAIAN------------ALDGQVELSFDLAELRGDFY---PATGFSLDLRDL..................... 306
4 -5.920PF01336.25; TIAS_METAC/272-345; OB-fold nucleic acid binding domain  ali follow..  15  1................................................................YRFEGTVSAKTIEGGHVIFAVRDGKGDEIDCAAFEP---TKNFRVLARRLLLGDQIFLSGSV-----TSGTLNIEKMQV....................................................................................................................................................................................................................................................................................................................................................................... 73
5 -5.800PF16100.5; I3IYQ1_ORENI/15-142; RecQ-mediated genome instability protein 2  ali follow..  17  38..............................................................SLVWMQGTVLEVQQDRDT--VLLMDETGT-FVVQGVNNIPKG------KPCLSQGKYVMVMGII-QAVSPEPVIRAVKMADLSEL................................................................................................................................................................................................................................................................................................................................................................... 112
6 -5.580PF01411.19; SYA_HAEIN/6-555; tRNA synthetases class II (A)  ali follow..  14  1..................................................................................................................................................................EIRQSFLDFFHSKG---------------HQVVESSSLVPENDPTLLFTNAGMN--QFKDVFLGMDKRPYSRATTA---RCVRPGGKHNDLE------NVGYTARHHTFFEMLGNF-SFGDYQDAINFAWEYLTQWLGLPKEKLWVTVYETDDEAYNIWNKDVGVPAERIIRIGDNKGSPYASDNFWAMCTEIFYDHGDHIWGGPPGSPEEDGDRYIE-NVVFMQFNRLADGTMEKLPRPSVDTGMGLERISAVLQHVN-SNYEIDIFKTLIAK---TAEIVGATDLTNKSLRVIADHIRSCAYLIPSNEGRGYVLRRII.................... 308
7 -5.500PF04076.13; YGIW_ECOLI/25-127; Bacterial OB fold (BOF) protein  ali follow..  18  29........................................................KSLRDDTWVTLRGNIVERISDDLYVF---KDASGT-INVDIDHKRWNGVT-------VTPKDTVEIQGEV-DKDWNSVEIDVKQIR........................................................................................................................................................................................................................................................................................................................................................................ 102
8 -5.480PF00596.21; P73359_SYNY3/18-220; Class II Aldolase and Adducin N-terminal domain  ali follow..  11  2...............................................................................................................QRVYTSRLLGREPSLVLHGGGNTSVKCQVTNLVGEKEDILYVKGSGWDLATIEAAGFAPVRMPHLLKLSKLTQLSDRQMVNELKTQMTLASAPSPSVETILHAILPFKYVDHTHADAVVTITNTANGEERIREIYGGFDLARVCAEKFAAE-VLMNHGIFSFGAIAREAYEGMISLVNEAEEYL............................................................................................................................................................................................................... 203
9 -5.460PF17191.4; A8F350_PSELT/110-273; RecG wedge domain  ali follow..  14  1...........EIKYAKRVGPRKEAILKKLGISTFPRDYEDRRKIIPI--------SEISFEGKLTTRGKVVNVETK-TITAAVLADGVSQLLLKWFNQEYLHKG-------QVLKNKTIYATGLVKHSQFGGIEMVNPEIEPEDGEILPIYPLTHGISQKERIVRENISCV.......................................................................................................................................................................................................................................................................................................................................... 164
10 -5.260PF03466.20; Q98I60_RHILO/88-294; LysR substrate binding domain  ali follow..  17  3................................................................................................................................RPSGVLRVTTTV-GWLTERVQEFIELYPEISLQLILANEELDLTMRQADCAIRLRQPQQPDLIQRRLFTVHFHLYAAPSYVAKHGKPASVSELRNHRIVTFGLSLQINDILSIKRAVQGGAGIAMLPDYVINKDSGLVQLLPETEVFDTYFAYPDAMKNQAKLHVFRDFIIAKA........................................................................................................................................................................................................ 206

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;