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Query: PF12574.8; A0A0F3MK43_9RICK/404-636; 120 KDa Rickettsia surface antigen, from PfamA32U

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst ILEDESFKKWQEQNQNKTLDDFKHSAAQMDNLTPETKELISKLGAAGYANILGSGANIEQAQEMSFAASFCTLDWATQSNAVGNTTRKTITNEAGEKVVDLVSHSHSVQLSASVNGATKTITKCRTIDIPSTVEKGPLDLALVAQDSTGKNMPESKAVYFTVHYDQDGKIVEMTHPEPLKFFSETPSSPAYTVINGEIFTLPITKEKYEQLHKEISQNMEEQYAKDHQLAADKLast
1 -7.550[H] COG0307 Riboflavin synthase alpha chain  ali follow..  15  34.......................................................................................................EGLETGASVAHNGCCLTVTEINGNQISFDLMKETLRITNLGALRVGDEVNVERAALMSGHIITTAEIAKILTSENVWFKVQDASLMKYILYKGFIISLTVGEVTPTRFCVHLIPETLERTTLGRKKLGER 179
2 -7.540[H] KOG3310 Riboflavin synthase alpha chain  ali follow..  20  34.......................................................................................................DDCHTGDSIAVNGTCLTVTDFDRYHFTVGIAPESLRLTNLGQCKAGDPVNLERAVFVQGHVDTVAEIVEKKQDGEFTFRPRDPFVLKYIVYKGYITSLTITHVDDSTFSIMMISYTQSKVIMAKKNVGDL 179
3 -6.250[C] KOG4110 NADH:ubiquinone oxidoreductase, NDUFS5/15kDa  ali follow..  22  115........................................................................................................DYSQMLAIDINPTLMGLKSCRE---PQELWKGCEEIPSTVTGDEGKKPKKQKTENFPVH--------------PVLYVIE--QYASQIEIGLEMIVVSVNRPKYSLLQKNNHENFGKD........... 218
4 -5.890[O] COG4934 Predicted protease  ali follow..  1265...............NELYISYNGNIIASEPITTSSGVLQINGNDLPYGILNLTFTIETANGQTNETSTVMNLPADEYYPTVNIIAPVTGSSQTGSLNITFTYTGFDDTVILYVNGSSGNVKNLYTITEGSSLPAGNYTVTVLVISKDGQVAKQSANFDLKAPVVPPVQSSIIIEYLVIGIVG------GLIV--GSLAVVAVMRRH.......................... 1459
5 -5.860[S] COG3330 Uncharacterized protein conserved in bacteria  ali follow..  12  340....................................................................................................IVYGATEPDATVTIGGRPIKLNEDGTFRFQMSFQDGLIDYPIVAVAVDGEQTRN-----VHMKFTRETPSRNTNTKEE....................................................... 412
6 -5.130[O] COG0501 Zn-dependent protease with chaperone function  ali follow..  11  51............................................................................................................................................KIVLKMYRAREVTPAESPNL---HRIVDGLLKANIPKPKVYVVDSGMPNAFATRNPQHAAVAVTTGILNLLSYE-EIEGVLAHELAHVKNRD. 140
7 -5.030[J] COG1859 RNA:NAD 2`-phosphotransferase  ali follow..  27...............................LDDSREEKLGRFVSGTLRHFPASAGVKMDEYGWVDLNAFCDVMKKRYNWMRKEYLYALVESDEKGRY-QIRGFMIRAR-----YGHSVNIELDYEESDAPYVYYGASPEEVDVLLENGIFPIKQRYVHLSTSYEKAAEVALIHTESPVILQVDEDGISLKLATDYIVLAEKIPPEYLYVIEE.................... 207
8 -4.950[S] COG1844 Uncharacterized protein conserved in archaea  ali follow..  12  8.........................................................................................................IRTDNFDKALTALSDLVRYGGMKIPRIIPPALSDWAFEQIVGEKPRKKVRAHVVAQVDLPASGRIRDIHPPAHIVVIP--VGTHVHKEILRLWGTFKELKGFHP........................ 115
9 -4.820[R] COG2520 Predicted methyltransferase  ali follow..  13  26...........................................................................PKCFDYVGDVAVISIPEELEAYRDSIVSKILSMRGNTRLNKVSKLEGEHRVARFELLSGDS----AETLHRENGYTYRMDRKVFFNPRLYWE-RVASKVLPGESVFAGVGPFVLPSAGKGAAVCAIEINPDACACLKENVRLNR.............. 172
10 -4.790[P] COG3338 Carbonic anhydrase  ali follow..  16  11..........................................LGALALTACTSPLKKEETHTHWGYTGHESPEHWAELSPEGKNQTPIDIKHTIDGKLAPIKLDYRPSNVEIVNNGHTIQV-DFKEASNRMQLNGKTFTLKQF-NLIRGKSFPME--AHF-VHADNEGNLAVLGVENQRL-----PKKRDYYRFSGSLTTPPCSEGVNWLVLKHYDNISQSQVE......... 228

FFAS is supported by the NIH grant R01-GM087218-01
1 3 5 0 8 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.