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Query: PF08568.10; Q6CFU3_YARLI/1-673; Uncharacterised protein family, YAP/Alf4/glomulin, from PfamA32U

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MQLTDDHKKDLEKLGEELKGKEEHTVAGEDEEDVNHGADDSEDAEDEDAEDENDYTELDVDIVCQFIKDAAREAEKTGDYISYATVIDIHCSDPSRYKHVDRVKILTSLLEVLRTNPKICEEIGWDLPALLLPYFNVEDFDFNDGLEGHPTFYPLIMLFSTLAEYGNPKELFLKTVETLSTLTCDRAPENDKLKFKQAESLRKFEVCKFHVLEELMSSCMKKIKTQYPSRFLASAASAILMFSARNAALFRHFPLIVGILARRVYVFIRDWGMDGDEPMDMSPDEQAKSAKILQSLSTYFFYSWFHRVAVRWSSNLFREIKHSIHELPRAERAKYDNPKSNGSAVYTIYNRWGTLALSLDLDPSQYFLPLIQEIQEDVQEATKGGLDDTLAGFSKSSLSDASPIAFVDYSMYDDASEIPLSQEGLLMLATQYMMENRDHSLNISLDQLVSLTLYLVHRSSPKEPLPFAITDLLLFWGWWTLKDMERPEVRQLDEAFYVKYLQFLVFISASSPLPEIRNIAYTLCGRLLYLQHESVSFAFIADTIADCPFENAQVAMVGILKRLMIPDEISDQLSKLRIPDVPTREGVEHQKASQTTIPTTPEHVDTIKSLCNAALEQENTHLVITWLNFLSTVKLDCGFAGDYAERVEKVIDEVEDENDRTLIRLALDVLAKTLast
1 -157.000PF08568.10; Q6CFU3_YARLI/1-673; Uncharacterised protein family, YAP/Alf4/glomulin  ali  100  1MQLTDDHKKDLEKLGEELKGKEEHTVAGEDEEDVNHGADDSEDAEDEDAEDENDYTELDVDIVCQFIKDAAREAEKTGDYISYATVIDIHCSDPSRYKHVDRVKILTSLLEVLRTNPKICEEIGWDLPALLLPYFNVEDFDFNDGLEGHPTFYPLIMLFSTLAEYGNPKELFLKTVETLSTLTCDRAPENDKLKFKQAESLRKFEVCKFHVLEELMSSCMKKIKTQYPSRFLASAASAILMFSARNAALFRHFPLIVGILARRVYVFIRDWGMDGDEPMDMSPDEQAKSAKILQSLSTYFFYSWFHRVAVRWSSNLFREIKHSIHELPRAERAKYDNPKSNGSAVYTIYNRWGTLALSLDLDPSQYFLPLIQEIQEDVQEATKGGLDDTLAGFSKSSLSDASPIAFVDYSMYDDASEIPLSQEGLLMLATQYMMENRDHSLNISLDQLVSLTLYLVHRSSPKEPLPFAITDLLLFWGWWTLKDMERPEVRQLDEAFYVKYLQFLVFISASSPLPEIRNIAYTLCGRLLYLQHESVSFAFIADTIADCPFENAQVAMVGILKRLMIPDEISDQLSKLRIPDVPTREGVEHQKASQTTIPTTPEHVDTIKSLCNAALEQENTHLVITWLNFLSTVKLDCGFAGDYAERVEKVIDEVEDENDRTLIRLALDVLAKT 673
2 -9.830PF00257.19; M4EQW9_BRARP/22-179; Dehydrin  ali follow..  10  1VQLTDEFGNPMHITGVATGETTTGEQQHHESLGEHLRRSGSSSSSSSEDDGQGGRRKKGMKDKIKEKLSGGKHKDEQTPSTATTTGPTTTTGAAAADQHHEKKGILEKIKEKLPGHH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 158
3 -9.270PF05786.14; G3J5P2_CORMM/14-857; Condensin complex subunit 2  ali follow..  12  15IPLNDDAEERGKR-INSRKALHDKQINQLKAAASGSRKSSLGIEDIENAAPGSNAGTPRASRGLDLSDDPIMINGVNLTPVKRVPILANF------------EEWMK-----MATDNKINATNSWNF---LIDYFHD----SLLKEGDGVNFQKASCTLDGCVKIYTNRSVATETGKLLSGLADSNSKKKADGEGGTGEESDDEVDED--------VKKKPKKKSQRSEATLAPSFTSL------QLKKFELEFSVDPLFKKASADF----------------DEGGAKGLLLNHL......................................................................................................................................................................................................................................................................................................................................................................................... 261
4 -8.800PF14961.6; W5NL29_LEPOC/12-1308; Broad-minded protein  ali follow..  32LEETDEHNYGFMYLRHYVENMEAETECCASGEGQGVGPGQDTLVHAVTRRTRESNEYKEMLSLKNTMMVAVESLINTFEFIKQEQLQAIAEKIDSSQPKEVRWEALQTLCCA--PPSDVLSCESWTLRRNLSAALGDPD---------PAFSDKVLKFYAKTFSSSPLREIYTSLAKHLESVFLSQKTSFSTAAGLDISNQDVARLLKKMRLLNEFQKEVTSFWIRNPEKYMEEIIESTLSLLSLNLDQSLKTTSADKVLEPIYFLSMLDIKAN----------KKWMHGYYSRTVVLRLLENKYKSLIVASLQQCINYYESCESSCDKTSNIAHVRQQQQTGTTQRMFYTARQLEYTYFVHSVCLLGRLLTHGRKLFPIKLKRRKDPVTLTDLIVILIRIMYRHPIPYYSEIPHVVVDSLSPACLVVLRTLCDRKECAVECLYAIAVIELLLSPIIALLKGKQVNLTSPETTLTHIADILARIATTERGL--------FLYDGNFIYTEGEGISAAHVIVQFTKKLLAD---------ISVLSEAGPLTSLKGAFIFVCRQMYNTCEGLQVLKPYGLHDCIAEAWKQTVSLSERVPTPVPGDCSSSATQDSQNNMVWEETLLDNLLNFALLLLQQTGAINECVTYM.......................... 705
5 -8.580PF14816.6; F7I216_CALJA/2-354; Family of unknown function, FAM178  ali follow..  15.YLLLEKREQEQKQERLLLQECLHLNSLDTDEDEMPLTPEHRLRQEDRLSSRVLDQPGQHGETPSLPKQNAKILVRCATILPPHSSLASMF----ISSPAQQLSFLRSLSTLYLHMPDCPVPL-W-LFQLLT--LSVDELFLQSDEDMHLWCPSLQEIREAFHSLGAYSPALYPLGPFWHSGRMLPGEAGLSENKHQDAPQEVTLDISLSHIYKFLSLCAQAQPGAYTDENLMDLIELLCRTLFLLLENIQEWPGKLQELCCVLSWVSDHHH---QFFPDVTSRSRCLRSQLSLVVIARMLG................................................................................................................................................................................................................................................................................................................................................................................... 349
6 -7.720PF18515.1; A5K696_PLAVS/164-420; Rh5 coiled-coil domain  ali follow..  16GFVCENDINNLYNIVTHLENPEHYKNKRYNYSKDREKFQKQLSSVHGCLLTNHKQNYKDMIYADTTIFDYLHYIYCYPEDKYYRDMLNISMGKINEYEQKKKNEAINKIIDVHETGAYVMRKIKEEL---------------NPSLNSDVADFVIDEIKYIIERLNAHSEKIKCASDFIKHIYKEKVQNEISKNELESNYIV---LSIHHGSFRFSTEHVIMLEEIFKSK-LHNICSKFLNELKNKITALINS.................................................................................................................................................................................................................................................................................................................................................................................................................................... 256
7 -7.030PF14631.6; U3I414_ANAPL/1-1417; Fanconi anaemia protein FancD2 nuclease  ali follow..  3......SKRKLSKTDASGENSKPDLPSRCSETKKPRASDKEKASAQGGLESEGVFEEL-LRTSGIILKAGEGQNEIAVDQMAFQKKLRLTLEK-HPTYPGVVKQFISGLESHIRDRNQFKNCL--SLIKMLL----------GINILQPAVITLLLEKIPEFFFDVVGTFLIVNQFKWLDGLLDSQDLVKK--------------------LMQMLSVSPVPIQHD-----IITSLPEILSQQSEVARELGCLLKEGRRLTVPILDALSRLDLDAELLAEVQQSAMTIVPSVKLEDLPVVVKFILHNVKAANAVEVISDLRKNLDLSSCVLPLQIVGSQKKLKSQVQTSSSTSQVTTSQNCVLFDVIKLAVRFQKDVSEAWIKAIENTTSVSDHKKVLDLIVLLLIHSTNTKNRKQAEKVLRSKI--CMPEQLMQNAFQDHSMVIRDFFPSILVLAQTFLHAAHPAIVSFGSCMYKQAFAVFDSYCQQ----------EVVSALVTHVCSGNEAELD-IALDVLTDLVVVHTSLLMVKTILDSTQKLNPCQIR-KLFYILSTLAFSQRQEGSRKWLSSTVPNHKQMGIIGAVTMIGSVALKRNEGDGGSSERPEPNFERDGQLSTLLDLV-CCEQTPEVLALYYDELANLIEKQKGNLDLQLLEEFGKSLVE. 664
8 -6.670PF14228.6; F6GVU1_VITVI/618-1735; Cell morphogenesis central region  ali follow..  29LELL----RCVRALRNDIRDSLYERFDNNLKNEENGDDIVQSCYWDSGRPFDMRRESDAIPPDATFQSILFESPDKNRWARCLSELVRYAAELCPSSVQEAKLEVIQRLAHITQDTDNKLDQ--WDLYHLIFPSLKSGSEAHIHAA--------------TMALGHSHLEVCEIMFGELASFIDE-METEGKPKWKSQKARREELRVHIANIYRTVSENIWPGMLGRKPIFRLHYLKFIEETTRQILTAPSENFQEIQPLRYALASVLRSL------APEFVDSKSEKFDLRTRKRLFDLLLSWCDDTGSTWVQDGVSDYRREVERYKSSQHSRSKDSVDKLSFDKEVSEQVEAIQWA---RVISWINSLFNEPAPRAPFGYSPADPRTPSYSKYTGEGPRGAAGRDRHRGGHLRVSLAKMALKNLLLTNLDLFPACIDQCYYSDAAIADGYFSVLAEVYMRQEIPKCEIQRLLSLILYKVVDPNRQ------RDDALQMLETLSVAAVVGNLPDSYQQFQYKLSCKLAKDHPELSQLLCEEIQLDAVDIIAQHQVLTCMAPWIENLNFWKLKDSGWSERLLKSLYYVTWRHGDQFPDEIEKLWSTI------ASKPRNISPVLDFLITKGIEDCDSNASAEISGAFATYFSVAKRICPQRTIDHLVYQLAQR 756
9 -6.440PF15313.6; H0V9E3_CAVPO/32-167; Hexamethylene bis-acetamide-inducible protein  ali follow..  14  46..LMDDHDQEEPDLKTG-LCPRRAAKSDSSDEDFLEEAGEEDGGSDGMGGDGGEFLQRDFSETYERYHAESLQNMSKQELIREYLELEKCLSRM................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 136
10 -6.420PF09174.10; U4LAW3_PYROM/25-204; Maf1 regulator  ali follow..  10TKAAGADKKLYKSISNTLSSRYESDLRLSESLSPPHSSSLQSQAVYKTLHSPGPLDQISARKTFAYMIATLNASHPDYDFSSV-------LRPSDFRREKNLRQVINTFNTTLFNLGVKSLPRIWDIIDEEMDLAACGVYSYQPQDVADDPYGEEGLLNIYFFFSKERKRVCY.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 178

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.