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Query: [J] COG0564 Pseudouridylate synthases, 23S RNA-specific, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLEIPAPTAVFSFVIDEQLTGRLDKGLVSYNGAYSRAFYQQQIELGRVRVNGRVYTRVSHPLSLGDVVEVELIEEEEPSSLIPEDIPLDKVYEDDMMLVINKPRDMVVHPAPGHTQGTVVHALLHEIGERLKQEFPEEPWRPGIVHRLDKDTSGLLITVKTRRAKALYSELFATKQVKKLYVAICINAPSQERIHTRIARHPLKRKEMTVLSTHAEGGKEAITHCQVLATNGRLSVVALYPETGRTHQLRVHMKHLGTPILGDPVYGIPSINFRYGLDKQQLHAYSLVFAHPESAERVKLVTKLPDDMTSLIEKEFREGVSILDGSCDWFKITRLast
1 -130.000[J] COG0564 Pseudouridylate synthases, 23S RNA-specific  ali  100  1MLEIPAPTAVFSFVIDEQLTGRLDKGLVSYNGAYSRAFYQQQIELGRVRVNGRVYTRVSHPLSLGDVVEVELIEEEEPSSLIPEDIPLDKVYEDDMMLVINKPRDMVVHPAPGHTQGTVVHALLHEIGERLKQEFPEEPWRPGIVHRLDKDTSGLLITVKTRRAKALYSELFATKQVKKLYVAICINAPSQERIHTRIARHPLKRKEMTVLSTHAEGGKEAITHCQVLATNGRLSVVALYPETGRTHQLRVHMKHLGTPILGDPVYGIPSINFRYGLDKQQLHAYSLVFAHPESAERVKLVTKLPDDMTSLIEKEFREGVSILDGSCDWFKITR 334
2 -75.300[A] KOG1919 RNA pseudouridylate synthases  ali follow..  25  35............FAKLRWYGKTLLEVFNTEFRDRESGYYEKAIRNGQVKVNNQIG-NVDTLIENGYIVSHHAHRHEPP----VSDQPVGIVHEDESYVVIDKPAGVPVHPTGRYNHNTVLHILMKEN----------KCSLLYPCNRLDRLTSGLMFFSKSPKAAEEMRVHMISKSLKKEYVARVIGEFPNVICDAPLLTVAPTLGLNRI----HPDGKEASTVFKRIAFDGHTSLVLCKPLTGRTHQLRVHLQYLGYPIANDPIYANKREGSNESVIMRLSEIGKTETASPLLQYEWYTNETEAEAKARRDKRLGE................. 333
3 -21.600[J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases  ali follow..  20  45.VKASTHSVKPTVKNPLVEGEKLQKVLARA----SRREIEAMIAENRVSVDGKI-------ATLGDRID---VHAGVKIRIDGHLINLLHA-EVCRVLMYYKPEGELCTRHDPEGRPTVFDRLPRLTGS-----------RWIAVGRLDINTSGLLLFTTDGELANRLMH--PSREVEREYSVRVFGQVDEAMLH---------RLKKGVQ----EDGPANFKEIKFAGGVGMNQWFDVTLMEGRNREVRRLWESQGVQV.......................................................................... 268
4 -20.400[S] KOG4837 Uncharacterized conserved protein  ali follow..  15  64.DEDFKDERDSKVVKTKVNSLRADLLLKAGL-GMARNKVELNFYESKIRVNGKKLPKKSAQLEVGDEIDV-IRGFSQSNPSHLVVARVSIL-EEGLSVHLRRYKSLLVENYRGPNAFKSSEHVAH................................................................................................................................................................................................................. 189
5 -17.500[S] COG4332 Uncharacterized protein conserved in bacteria  ali follow..  20  124.ASESAATLELQLGLEMPTSLRLDRLLASEL-GISRSRLQTLAERRLLVVDPDGAKALRKPARQGMTIRIDLAGEPDHE------------------AIICAAGG..................................................................................................................................................................................................................................... 208
6 -14.700[J] COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)  ali follow..  19  1............MKEKSSVEVRLDKWLWAARFYKTRAMAREMIEGGKVHYNGQRS-KPSKIVELNATLTLRQGNDERTVIVKAPASEAVALYEEEKMAQARKLNALTMPHPDRRPD.......................................................................................................................................................................................................................... 117
7 -12.700[S] COG2501 Uncharacterized conserved protein  ali follow..  25  8................DTEMITLGQFLKLADVIQSGGMAKWFLSEHEVLVNDEPDNRRGRKLYVGDVVEIE....................................................................................................................................................................................................................................................................... 62
8 -10.700[J] COG0522 Ribosomal protein S4 and related proteins  ali follow..  26  76YKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAIMVNGRVVNIASYQVSPNDVVSIR....................................................................................................................................................................................................................................................................... 146
9 -9.470[J] KOG3301 Ribosomal protein S4  ali follow..  15  88.ETRMKLDYVLALRIEDFLERRLQTQVFKLGLAKSIHHARVLIFQRHIRVGKQIVNVPSFVVRLDTQKHIDFALSSPYGGGRPGRCK....................................................................................................................................................................................................................................................... 173
10 -9.120[S] COG2302 Uncharacterized conserved protein, contains S4-like domain  ali follow..  18  162LANAVYAPVVWEEMGLTVSSMRLDVIISNAH-HISRQKAKQLVTAGLVKVNWKTVENPDFECEEEDVLSAR....................................................................................................................................................................................................................................................................... 231

FFAS is supported by the NIH grant R01-GM087218-01
1 2 4 1 8 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sasin JM, Godzik A, Bujnicki JM. SURF'S UP! - protein classification by surface comparisons. J Biosci. 2007 Jan;32(1):97-100.