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Query: [R] COG4797 Predicted regulatory domain of a methyltransferase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst DTSLTAMFIGNLPTQAAEKLQAINDIVRTEQYMDFITNRKFRSTLLCHQNIPINRKIEFNNLKEFFTSLNIRPVILEKAVDLTNEQENVSFYYENLPEPFISTTSPIMKAILYVYAENISNPISLEQVAKEAFKKLGKYQLQDFLAALEQHFIIFIFQGYLKIFETKPHAIATITEKPKTSEFARYQAKQAYFNNVTSVFSVTNRLNDMVGIPIHEKYILEMLDGTHNIDDIKKGVLEKINSKLLTARDDKGQEVTDPKLLKEFVDYVVNTSLEKFRMNYLLVELast
1 -97.100[R] COG4797 Predicted regulatory domain of a methyltransferase  ali  100  1DTSLTAMFIGNLPTQAAEKLQAINDIVRTEQYMDFITNRKFRSTLLCHQNIPINRKIEFNNLKEFFTSLNIRPVILEKAVDLTNEQENVSFYYENLPEPFISTTSPIMKAILYVYAENISNPISLEQVAKEAFKKLGKYQLQDFLAALEQHFIIFIFQGYLKIFETKPHAIATITEKPKTSEFARYQAKQAYFNNVTSVFSVTNRLNDMVGIPIHEKYILEMLDGTHNIDDIKKGVLEKINSKLLTARDDKGQEVTDPKLLKEFVDYVVNTSLEKFRMNYLLVE 284
2 -6.220[A] KOG2098 Predicted N6-adenine RNA methylase  ali follow..  11  1...........................MSDTWSSIQAHKKQLDSL--RERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDL---ALTLPTDAVSICLAISTPDAPATQDGVESLLQKFAAQELIEVKRDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLN...... 251
3 -5.690[S] COG3219 Uncharacterized protein conserved in bacteria  ali follow..  1..........................MQPEISAQY--QHRFAQAIREGEAADGLPQERLNVYIRL---------------------------IRNNIHSFIDRCYTETRQYFGFVRDAHAQTPYFQEIPGEFLQYCQSLPLLDGILALMDTQLLAEVAQIPDIPDIHYSNDSKYTPSPAAFIRQYRYDVTDDLHEAETALLIWRNAEDDVTLDGFDMMLLEIMSSALSFDTLAQTLVEFMPE-------------------DDNWKNILLGKWSGWTEQRIIIP 227
4 -5.410[S] COG4860 Uncharacterized protein conserved in archaea  ali follow..  5...........................................................................................................................................................................................................................IKVVNDPGELVSIFHAADSEVKRKLLLDLSTGWITLPV---IEQKYGKEGRRALLYLDKIKMI.. 64
5 -5.180[CE] COG0473 Isocitrate/isopropylmalate dehydrogenase  ali follow..  131................................FDMVTVRELTGGIYFGQPKGREGEGANEKAFDTEVYHRYEIERIARVA---ETAMKRSKHVTSVDKANVLISSVLWREVVCDVAKDYPEVTLDHIYIDNATMQLIKQPEFFDVSNIFGDIISDECAMITG----------SMGMLPSASLNEKGFGLYEPAGGSAPDIAGKGIANPIAQILSAAMMLRHSFNLNDAATAIENAVKNVLAEGHRTADLADESQPLSTKQMGDLIAQAVE.............. 359
6 -4.860[Q] COG3207 Pyoverdine/dityrosine biosynthesis protein  ali follow..  10  2......TFTSNLPSSSEQSISP-DLSTYSKFLALYCRSDKCDDFYSLEEKQNCKFGDQWLDFINTIHNLDFSESEVSGRVSERILPASLANKFTNNLGVAIKISEQIRGCVTTVENENSFNNWFVYHILDQSQLSLSEHPIVTKEVKYHELFADFFEKNLKNTIVND---QWNFGGRDYFIERSRYFTDR----------------YLRIECDKGEELALKRL------IKATQDLVKIYPPGMKIWIVSDGHVFSDCIGVDDDVVSTYTTKLHELYK...... 296
7 -4.730[E] KOG0784 Isocitrate dehydrogenase, gamma subunit  ali follow..  10  155................................LDFVIVREQTEGEYS----SLEHELVPGVIECLKISTRTKAERIAKFAFDYATKTGRKKVTAVHKANIMKLGDGLFLRTCEGVAKQYPKIQFESMIIDNTCMQLVSKPEQFDVPNLYGNIIDNLAAGLVG----------GAGVVPGQSVGRDFVIFEPGSRHSFQEAMGRSIANPTAMI--CAANMLNHLHLDAWGNSLRQAVADVVKEGKVRTRDLGGYATTVD------FADAVIDKFRI......... 379
8 -4.710[K] COG2101 TATA-box binding protein (TBP), component of TFIID and TFIIIB  ali follow..  1......................................................................................................MSEREKITIENIVASSLAEHLDLSRIALALDGSEYEPEQFPGLIYRLQTAVLIFRSGKVNCTGAKNIEDVKRTIKIIIDKLKAANIEVYDDPDIVQNIVAVYDLESELNLTDIAMS-LGLENVEYEPEQFPGLVYRVEEPRVVLLLFGSGKVVCTGAKEESEIEQAVIKVKKELQKVGLI.. 184
9 -4.650[E] KOG0785 Isocitrate dehydrogenase, alpha subunit  ali follow..  133................................VDVVTIRENTEGEYS----GIEHEIVPGVVQSIKLITETASRNVASFAFEYARQNGRKVVTAVHKANIMRQSDGLFLSICREQAALYPDIKFKEAYLDTVCLNMVQDPSQYDVGDILSDLCAGLVGGLVTPSGNIGKGAAVFDEIQFFIQTKLTKFLYRSVHGTAPDIAGQDKANPTALL--SAVMMLRYMNLPQHAARIEKAVFDAIADGRAKTGDLGGTGTCSS------FTADVCARVKDLE....... 374
10 -4.510[S] COG2733 Predicted membrane protein  ali follow..  82.........DRIGENLGQFVQ--KKFLDTQSLVALIRRHEPALLIGNWFSQPENARRVGQHLLQIGFLELTDDARIQRLLKRAVHRAIDKVDLSGTSALMLESHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEHPLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDPEMTADAVKSYLKEKERIARAGQWFGETLIADDALRASLNGHLEQAAHRVAPEFSAFLTDARDMSRQIELNIGKDLQFIRVNGTLV. 400

FFAS is supported by the NIH grant R01-GM087218-01
1 3 0 5 6 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.