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Query: [U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGNSLFKGFSKPFSRLFSNKEMRILMLGLDAAGKTTILYKLKLNQSVVTIPTVGFNVETVTYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSADSNRISEARQELHRIISDREMRDCLLLVLANKQDLPGALSPAQITDVLQLDKLKDRLWNVQPTCALTGDGLLEGLAWLSQNAKLKLast
1 -98.700[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali  100  1MGNSLFKGFSKPFSRLFSNKEMRILMLGLDAAGKTTILYKLKLNQSVVTIPTVGFNVETVTYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSADSNRISEARQELHRIISDREMRDCLLLVLANKQDLPGALSPAQITDVLQLDKLKDRLWNVQPTCALTGDGLLEGLAWLSQNAKLK 184
2 -96.500[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  67  1....MGLSFGKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASK 180
3 -96.300[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  47  1....MDGGVLSYFRGLLGSREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQSR 180
4 -94.800[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  40  1....MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK 180
5 -94.100[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  42  3.......LLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSSNAIREALELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSR 179
6 -94.000[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  53  1MGNIFSSMFDKLWGS---NKELRILILGLDGAGKTTILYRLQIGEVVTTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTASKELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKEE 181
7 -89.400[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  32  4....LINRILEWFKSIFWKEEMELTLVGLQFSGKTTFVNVIASGQFADMIPTVGFNMRKITRGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAADLDKLEASRNELHSLLDKPQLAGIPVLVLGNKRDLPGALDETGLIERMNLSSIQDREICCYSISCKEKDNIDITLQWLIQHSKSQ 184
8 -86.800[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  32  3...LFDWFYGILASLGLWQKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKIKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYDKERFAESKRELDALLSDEALATVPFLILGNKIDIPYAASEDELRYHLGLTNFTTRPLEVFMCSIVRKMGYGEGFKWLSQYIN.. 193
9 -84.100[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  33  1....MFHLVKGLYNNWNKKEQYSILILGLDNAGKTTFLETLKFKALEKIQPTVGQNVATIPVDSKQLKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRERLDECSTTLQSVVMDEEIEGVPILMLANKQDRQDRMEVQDIKEVFNKEHISARDSRVLPISALTGEGVKDAIEWMIVRLERN 189
10 -53.000[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  20  38...LLATIWLLSIRLFRRTKSNTVLLSGLSGSGKTVLFYQLRDGSSHGAVTSMEPNEGTFKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALEFLPIRAASEYLYDILTNASVNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEIDKLRVSRSAISTADIANDFTLGIEGEVFSFSH. 230
11 -39.100[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  21  46....TEEGVLDFSDPFSTEVKPRILLMGLRRSGKSSIQKVVSPNETLFLESTNKICREDVSNSFVNFQIWDFPGQIDFFDPYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDDKIHLSFYLTSIYDHSIFEAFSKVVQKLIPQ 240
12 -34.200[R] COG2229 Predicted GTPase  ali follow..  18  2...................RENKIIFTGPVGVGKTTAIAAISDEALVQTNTTVAMDYGAISLEDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNARTNPLKDLEFFLHSF--RGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAKHNLN-----VFEIDARKEDDVKQLVSAMLFSIDPG 175
13 -32.900[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  20  10.....................FRLILIGDSTVGKSSLLKFFTDGKFALSDPTVGFFARLIEMKDIKLQLWDTAGQERFRSITKSYYRNSVGVLLVYDISNHASFEHIPLWMMEAQRHIEPHRPVFALVGCKLDLINAGGHREVTTEEAQKFAKQHGLHFVETSARSGANVEEAFRMVTQEVYAR 178
14 -32.100[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  18  13.....................FKLVLVGDGGTGKTTFVKRHLTGEFEKKIATIGVEVHPTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDL--VRVCENIPIVLCGNKVDVKERKVKAK-----TITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGN 173
15 -31.600[U] KOG0081 GTPase Rab27, small G protein superfamily  ali follow..  20  10.....................IKFLALGDSGVGKTSVLYQYTDGKFNKFITTVGFREKRVVYQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLE---DQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKR 184
16 -30.900[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  19  9.....................LKILIIGESGVGKSSLLLRFTDDTFDELAATIGVDFKSVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFA----RKHSMLFIEASAKTCDGVQCAFEELVEKIIQT 172
17 -30.800[R] KOG0394 Ras-related GTPase  ali follow..  17  9.....................LKVIILGDSGVGKTSLMNQYVNKKFSNQKATIGFLTKEVQFEDFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSMKSFENLNEEFLIQASPSDPENFPFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNVEEAFQCIAKDALKS 179
18 -29.800[TU] KOG0084 GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins  ali follow..  22  9.....................FKLLLIGDSGVGKSCLLLRFADDSYLSYISTIGFKIRTVEQDGIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTDLESFNNVKQWLNEIDRYAS-ENVNKLLVGNKCDLT---SQKVVSTETAKAFADELGIPFLETSAKNATNVEEAFMAMTAAIKTR 172
19 -29.800[TU] KOG0078 GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins  ali follow..  19  10.....................IKLLLIGDSGVGKSCLLLRFSEDSFTSFITTIGIDFKELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTDKKSFDNVRTWFSNV-EQHASENVYKILIGNKCDCE---DQRQVSFEQGQALADELGVKFLEASAKTNVNVDEAFFTLAREIKKQ 173
20 -29.800[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  20  21.....................FKLVLLGESAVGKSSLVLRFVKGQFHEFESTIGFLTQTVCLDDVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQAS-PNIVIALSGNKADLA---NKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKN 184
21 -29.800[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  17  11.....................FKLLIIGDSGVGKSSLLLRFADNTFSNYITTIGFKIRTMDINGVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTNGESFGNVKRWLQEI--ENNCDSVQKVLVGNKCEEN---ERRVVLESDARNYAQSMNISFFETSAKEDKNVEPMFTCITSLVLTA 173
22 -29.800[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  20  13.....................FKIVLLGEGCVGKSSLVLRFVENKFSKHLSTIQFQNKTVNVEDADLHIWDTAGQEKYHALGPIYYRGSNGVLLVFDITDRKSFEKVKNWVLEIKTCLG-NTAEILIVGNKIDLE---EERQVTRQDAEAYAESEGALYMETSAQDNVGISDAFESLTAKMIEH 176
23 -29.600[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  19  10.....................YKLVFLGDQSVGKTSIITRFMYDKFDTTQATIGFLSKTMYLEDVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVANRLSFLNTSKWIEEVRNERA-GDVIIVLVGNKTDLV---EKRQVSIEEGDSKGREYGVMFIETSAKAGFNIKPLFRKIAAALPGM 173
24 -29.500[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  18  10.....................FKIVLIGNAGVGKTCLVRRFTQGLFPGQGATIGFMIKTVEINGVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYAS-NKVITVLVGNKIDLA---ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISE 173
25 -29.300[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  21  9.....................FKFLVIGSAGTGKSCLLHQFIENKFKDSNHTIGVEFGNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLAS-PNIVVILCGNKKDLD---PEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNK 172
26 -29.300[U] KOG0093 GTPase Rab3, small G protein superfamily  ali follow..  20  23.....................FKILIIGNSSVGKTSFLFRYADDSFTAFVSTVGFKVKTIYRNDIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI-KTYSWDNAQVLLVGNKCDME---DERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEK 186
27 -29.000[T] KOG4252 GTP-binding protein  ali follow..  16  10.....................IKMVVVGNGAVGKSSMIQRYCKGIFTDYKKTIGFLERQIQVNDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRGSFEAVSSWREKV--VAEVGDIPTVLVQNKIDLL---DDSCIKNEEAEALAKRLRLRFYRTSVKEDLNVNEVFKYLAEKYLQK 172
28 -28.800[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  17  12.....................FKYIIIGDMGVGKSCLLHQFTEKKFMDCPHTIGFGTRIIEVSGIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTN-PNTVIILIGNKADLE---AQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQN 175
29 -28.700[T] KOG3886 GTP-binding protein  ali follow..  18  38..................AMKKKVLLMGKSGSGKTSMRSIIFANDTRRLGATILDRIHSLQIGNLVLNLWDCGGQDTFMENYDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSDAKIFCLVHKMDLVQEDQRDLIFKERELRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPN 244
30 -28.600[R] KOG1673 Ras GTPases  ali follow..  16  102.....................LKISLLGDCQTGKTTFVVKYVGDENQSFLEMTGLNLMDVQGVTISFSIWDVGGDEKSKDHIPIACKDAVAILFMFDLTSRSTLNSVFGWYSQA--RKWNKTAIPILIGTKFDDFVRLPPNWTIVTQARAYAKVMNASLFFSSATHNINVNKIFKFILARLFNL 269
31 -28.600[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  17  11.....................FKTVLIGDSGVGKSNLLMRFTRNEFNESKSTIGFATRNIVLDNIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITKQSSFDNVGRWLKELREHAD-SNIVIMLVGNKTDLL---HLRAVSTEEAQAFAAENNLSFIETSAMDASNVEEAFQTVLTEIFRI 174
32 -28.600[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  19  7.....................FKYIIIGDTGVGKSCLLLQFTDKRFQPVDLTIGFGARMVTIDGIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSN-SNMVIMLIGNKSDLE---ARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRK 170
33 -28.300[R] KOG0395 Ras-related GTPase  ali follow..  17  17..................KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQTPTIEFHRKVYNIRGYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILETKEAAELPMVICGNKNDHGELCRQVPTTEAELLVS-GDENCAYFEVSAKKNTNVDEMFYVLFSMAKLP 193
34 -27.000[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  22  469.....................GKVIMLGDSGVGKTSLLIRFRDGRYVPSLSTVGIDFRVVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEI-REYAQEDVVIVLIGNKADCSG--SERQVKREDGERLGREHNVPFMETSAKTGLNVELSFTAVARQLKSR 634
35 -23.100[R] COG1084 Predicted GTPase  ali follow..  16  160..................LDAFTVVIAGFPNVGKSTLLRTLTGAEPEVA-TTKGIQIGHLERKWKRIQVIDTPGNNIELQAMVALENIADVIMFIFDASETCG-YTLESQYSLYLGIRSVFDIPVVTVFNKMDL--------AENVKYLEEYINMVEDPLKVSAFEGRGVSKIIKKLEGLYEKE 328
36 -21.800[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  19  2...................QAIKCVVVGDGAVGKTCLLLSYTTNAFPGEILTVFDTYSMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSH-HCPNTPIILVGTKADLREDRDTIERLRESRLQPVSHTQ-KYLECSALTQIGLKQVFD......... 170
37 -21.400[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  12  1.......MWMGVGDSSGSPKPIRIVVVGEKGSGKSSLIMAAARNTFHPNIPSLLPYTNEFFPDRIPATVIDTSSRPEDKGKVVKEVRQADAIVLTFAFDRPETLDRLSKYWLPLFRQLE-VRVPIIVAGYEVDNKEAYNHFSIEQITSALMKQYRE-TSIQWSAQRLDQAKDVLYYAQKAV... 177
38 -21.400[R] COG3596 Predicted GTPase  ali follow..  13  36..................HYEPVIGIMGKTGAGKSSLCNALFAGEVSPVSDVAACTRDRLQIGEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADD--RALATDEHFYRQVIGEA-YRHKMLFVISQSDKAEPTSGGNILSTEQKQNISRKI-PVCAVSVRLQWGLRVMAERMIKCLPRE 219
39 -20.500[R] KOG2486 Predicted GTPase  ali follow..  14  137......................EFALVGRSNVGKSSLLNSLVRRKRLALTSKKPGKTQCINHFRIKWYLVDLPGKQDWNKFTKDYFSTLVSVFLLVDA--SIPVKPIDLEYASWLGQ---NQVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDL--PWIMTSSVTNQGRDEILLHMAQLRNY. 314
40 -20.400[E] COG4917 Ethanolamine utilization protein  ali follow..  17  3......................RIAFVGSVGAGKTTLFNALQGNYTLAR------KTQAVEFNDKGDI--DTPGHPRWYHALITTLQDVDMLIYVHGANDPESRLPAG--------LDIGVSKRQIAVISKTDMPDA-DVAATRKLLLETGFEEP---MFELNSHDPQSVQQLVDYLASLTKQE 149
41 -19.000[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  20  337..................KSIADLGLIGLPNAGKSTILNKISNAKFTTLSPTIG--TVSLGFGQDVFTVADIPGDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREKT............... 499
42 -18.700[T] KOG0099 G protein subunit Galphas, small G protein superfamily  ali follow..  30  38..................RATHRLLLLGAGESGKSTIVKQMRIDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVEDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDL.................................................. 296
43 -18.700[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  15  171.......................VLICGYPNVGKSSFMNKVTRADVDVQFTTKSLFVGHTDYKYLRYQVIDTPG-EMCSITALAHLRAAVLFFLDISGSCGYTIAQQAALFHSI--KSLFMNKPLVIVCNKTDLMPMENISEEDRKLKTAMGASEEQVLLKMSTLTDEGVMSVKNAACERLLDQ 352
44 -18.500[T] KOG0085 G protein subunit Galphaq/Galphay, small G protein superfamily  ali follow..  25  37..................RRELKLLLLGTGESGKSTFIKQMRIDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLEDKILYSHLVDYFDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQL 351
45 -18.500[DT] KOG0082 G-protein alpha subunit (small G protein superfamily)  ali follow..  26  31..................ARTVKLLLLGAGESGKSTIVKQMKIDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDI.................................................. 273
46 -17.500[R] COG1160 Predicted GTPases  ali follow..  18  5......................VVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKHIAGYDFIVIDTGGEEKMAEQSLLAIDEADIVLFLVDA--RAGLTAADIGIANYLRQR--QNKITVVVANKTDGIDADSHCAEFYQLGLGE-------IEQIAASQGRGVTQLMEQVLAPFAEK 167
47 -17.000[R] COG0218 Predicted GTPase  ali follow..  16  27......................EIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIKMRFVDVPGSKKEREKWEEYLTTRENLRAVVSLVDLRHDPSADDV--QMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL... 195
48 -16.300[P] COG0370 Fe2+ transport system protein B  ali follow..  17  2...................SQNTYCILGNPNTGKTSLFNALTSYEYVGNWSGVTVEKKVGTLRSKTGKLIDLPGIYDLNPVVTRFLEKFDCMLNIVDSSQIERNLNLTVQLLEY-------GAPVVMGLNMIDVAAGLNIQNLAKKLRIP--------ILPVVARSGKGTEDILSTLSEKHVAP 164
49 -15.700[S] KOG4273 Uncharacterized conserved protein  ali follow..  16  2..................ESRPGVLVVGSSGVGKRTLLSRLLSVEFEDSSSSSQTEVHNTKYYTADVSVCISHICDEYSLPNLPNSHPLVALVMVFDLSELSTLVALQDWVSHT---DINSFDILLCIGNKVDREYRRRLLKASDPSRDLYSDIDDFGISETEGSSLLGSEDALEWCSEN.... 181
50 -15.700[R] COG0536 Predicted GTPase  ali follow..  20  155....................ELKSMLVGFPSAGKSSLISVMSAAKFTTLQPNLGV----VNVGHETFTMADVPGGKGLGLDFLRHIERTSVLVHVVDTATMDPGRDPISDIEALEAE-DLSQRPRLVVLNKADVPEA---EELAEFLKEDIEKQFGWPVFIISAVARKGLDPLKYKLLEIVQD. 342
51 -14.800[R] COG0486 Predicted GTPase  ali follow..  13  211....LDHVRSEAKQGSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLRIDGMPLHIIDTAGLREATDE-WSEIEQADRILLMLDSTEA--DNQDLEKVRSEFLTKLPSNIPVTIVRNKADLSGENEGIVEQNGYTVITL----------SAKTQQGIALLREHLKQSMGYQ 390
52 -14.500[R] COG1163 Predicted GTPase  ali follow..  16  60...............VARTGVASVGFVGFPSVGKSTLLSKLTGTEFTTLVTVPGV----IRYKGAKIQMLDLPGGRGRGKQVIAVARTCNLLFIILDVNKPHHKQIIEKELEGV--GIRLNKTPPDILIKKKEKGGI............................................... 190
53 -14.400[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  17  59...............VAKTGDARIGFVGFPSVGKSTLLSNLAGVYFTTLTTVPGV----IRYKGAKIQLLDLPGGKGRGRQVIAVARTCNLILIVLDVLKPGHKKIIENELEGF--GIRLNSKPPNIGFKKKDKGGI............................................... 189
54 -13.900[R] COG1159 GTPase  ali follow..  16  11.......................IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRITEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTRWTPDDE------MVLNKLRDGKAPVILAVNKVDN--VQEKVDLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPE. 175
55 -13.800[J] KOG1191 Mitochondrial GTPase  ali follow..  12  337....VESALDTANYDKLLQSGLQIAIVGRPNVGKSSLLNAWSKSERAIVTEVAGTTRDVVEVRGVPITLLDTAGIRETNDI-ETAAKVADVIIMAVSAVEGWTEEDTEVSFYDLFGGLLYLKQPMILVMNKIDCAPPGSCDQLEDQRKKEEVFHKSVFT---SAVTGQGIEELEDAILEILGL. 535
56 -13.700[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali follow..  21  183.......................VTIMGHVDHGKTTLLDKFRKTQVAAITQHIGFLVSLPSGEKITFL--DTPGHAAFSAMRARGAQVTDIVVLVVAADD------VMKQTVESIQHAKDAQVPIILAVNKCDKAEA-DPEKVKKELLAYDVVCEDYQAVPVSALTGDNLMALAEATV...... 339
57 -13.700[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  15  57...............VTKYGHGRVALIGFPSVGKSTLLTMLTGTHFTTLTCIPGV----IHYNDTKIQLLDLPGGKGRGRQVIAVAKSSDLVLMVLDSKSEGHRQILTKELEAV--GLRLNKTPPQIYFKKKKTGGI............................................... 187
58 -13.000[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  13  34.............EVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNRSCGSSMPDEFPVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAI---EIMKLKHILILQNKIDLVKERQAKEQYEQILVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIP.. 244
59 -12.900[R] KOG0410 Predicted GTP binding protein  ali follow..  19  312.......................VSLVGYTNAGKSTLLNQLTGANVLRLFATLDPTTRRVQMNGKEFLLTDTVGPTTLVAAFRATLEESSLLVHVVDISHPL-AEQQIEAVEKVMSELDVSSIPKLVVWNKVDRVDDPQKVKLEAEETGDTI--------CISALTGEGLDDFCNAVHEKLKDS 475
60 -12.800[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  16  2..................KRPLIIGVGGPVGAGKTMLIERLYLSTKGYSMAAITNDIYTDKHPDLQLLFLESGGDNLSATF---SPDLVDFSIYIIDVAQGEKIPRKGGQGMIKSD---------LFIINKVDLAPYVGANVEVMKADTLKSRGNK-DFFVTNLKTDEGLKSVADWIEKRLQLA 202
61 -12.700[J] COG4108 Peptide chain release factor RF-3  ali follow..  17  13..................SKRRTFAIISHPDAGKTTITEKVRGSNQHAKSDSVTTSVMQFPYGDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAK------VEDRTRKLMEVTRLRDTPIVTFMNKLDREIR-LMDEVENELKIACS................................ 169
62 -12.600[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali follow..  20  448.......................VTIMGHVDHGKTTLLDRFRESRVTE---TQHIGAYQIKANGKKITFLDTPGHEAFTSMRARGASVTDITILVVAADD------VMPQTIEAINHSKAAGVPIIVAINKIDKPGA-NPQRVTQELTEHGVFPVAWEFVEISAKFNQNLDELLDTVL...... 605
63 -12.400[R] COG2262 GTPases  ali follow..  15  200.......................VSLVGYTNAGKSTLFNRITEARVYQLFATLDPTLRRIDVDVGETVLADTVGPHDLVAAFKATLQEATLLLHVIDAADVR-VQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPR-------IDRDEENKPIRVWLSAQTGAGIPQLFQALTERLSGE 364
64 -11.900[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  15  47........................IVAHVDH-GKSTLADRLGQKQMLDKLQTVKAQTAALRHRGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQ------VQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNLFEFNPEE--CLHISAKSGLNVDKVLEAIIDRV... 211
65 -11.600[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  13  7.................QKPHLNLITIGHVDHGKSTLVGRLRFKEERERGVTIDLAHRKFETDKYYFTLIDAPGHRDFVKNMITGTSQADAAILVISAREGEGVMEQTREHAFLARTLGVPQ--MVVAINKMDATSPPYSEKRYNEVKLRSIGFKDISFVPISGYKGDNVSPNMPW........ 206
66 -11.600[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  16  4.................EKVHINIVVIGHVDSGKSTTTGHLKLKAERERGITIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTEAGISKNGQTREHALLAQTLGVKQLIVACNKMDSTEP--TNEVSGFIKKIGYNPKAVPFVPISGFNGDNMLE............ 203
67 -11.300[M] COG0481 Membrane GTPase LepA  ali follow..  15  9........................IIAHIDH-GKSTLSDRLRERGITIKAQSVTLNYKAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQ------VEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDIVGIDAME--AVRCSAKTGVGIEDVLEEIVHKI... 180
68 -11.200[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  18  50.................KKPHVNIGTIGHVDHGKTTLTAAIKAPEEKARGITISSAHVEYETANRHYAHVDCPGHADYIKNMITGAATMDGAIIVVSATDGQ-MPQTREHLLLA---RQVGVKQIVVYINKVDMVEELVEMEMRELLSEYGFDGDNTPIVSGSALCA................. 218
69 -11.200[J] KOG0458 Elongation factor 1 alpha  ali follow..  17  164.................ALPHLSFVVLGHVDAGKSTLMGRLQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVD---KSKLLPYLVDIGFFEDNINWVPISGFSGEGVYK............ 361
70 -11.100[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  14  1...............MKNQSEINIGLVGHVDHGKTTLTKTHSEETKRGISIRLGYRCGTETELLRKVSFVDAPGHETLMATMLSGAALMDGAILVIAANEPCPQPQTKEHLMAL---DVIGVKDVIVVQNKIDIVSKERALESYREIKVKGTCAEDAPIIPVSAQQGANIDILIETIEERIK.. 198
71 -10.800[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  21  3.......................IVTSGHVDHGKTALLKALTGTSTAHLPETIDLGYAYLPLENKVLGFIDVPGHEKFLSNMLAGLGGVHYAMLIV-AADEGVAVQTKEHLAIL---RQLQFHEIIVVITKADRTNSAQIESLIQTIKQDYSFLRNANYFVTSAETGQGISELRHYLANLAELA 165
72 -10.700[J] KOG0468 U5 snRNP-specific protein  ali follow..  17  133......................NVALVGHLHHGKTTFVDCLQERGCSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDA-----AEGVMLNTERLLKHAVQERQAITVCINKIDRLILLPPQDAYFKLK.................................... 281
73 -10.600[J] KOG0459 Polypeptide release factor 3  ali follow..  15  98.................KKRHLNVVFIGHVDAGKSTIGGQITNEEERLKGKTVEVGRAHFETESTRFTILDAPGHKSYVPNMISGASQADIGVLVISARKETGYERGGQTREHVQLAKTLGVSKLIVVVNKMDDPTVNWSKERYDEIASGYNTKKDVVFLPISGLMGKNMDQ............ 298
74 -10.500[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  17  10........................IIAHVDH-GKTTLVDKLESERVMDSNDTILAKNTAIKWNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQD------PMPQTRFVTQKAFKAGLRPIVVVNKIDRPGARPDWVIDQIFDLFDNLGATDEQLDFPIVYASALN............. 169
75 -10.100[H] COG3172 Predicted ATPase/kinase involved in NAD metabolism  ali follow..  11  10......................TVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYSHLGGDEIALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTD-KKYEGREHPFVQALIDEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLE-IEFVRVEEEDYDSRFLRCVELVRE. 181

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Bossy-Wetzel E, Barsoum MJ, Godzik A., Schwarzenbacher R, Lipton SA. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr Opin Cell Biol. 2003 Dec;15(6):706-16. Review.