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Query: [R] KOG0075 GTP-binding ADP-ribosylation factor-like protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLALINRILEWFKSIFWKEEMELTLVGLQFSGKTTFVNVIASGQFAEDMIPTVGFNMRKITRGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAADLDKLEASRNELHSLLDKPQLAGIPVLVLGNKRDLPGALDETGLIERMNLSSIQDREICCYSISCKEKDNIDITLQWLIQHSKSQSRLast
1 -95.000[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali  100  1MLALINRILEWFKSIFWKEEMELTLVGLQFSGKTTFVNVIASGQFAEDMIPTVGFNMRKITRGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAADLDKLEASRNELHSLLDKPQLAGIPVLVLGNKRDLPGALDETGLIERMNLSSIQDREICCYSISCKEKDNIDITLQWLIQHSKSQSR 186
2 -89.700[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  30  1...MDGGVLSYFRGLLGSREMRILILGLDGAGKTTILYRLQVGEVV-TTIPTIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSADRDRIGISKDELLYMLREEELAGAILVVLANKQDMDGCMTVAEVHHALGLENLKNRTFQIFKTSATKGEGLDQAMDWLSNTLQSRK. 181
3 -89.400[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  32  5...LFKGFSKPFSRLFSNKEMRILMLGLDAAGKTTILYKLKLNQSV-VTIPTVGFNVETVTYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSADSNRISEARQELHRIISDREMRDCLLLVLANKQDLPGALSPAQITDVLQLDKLKDRLWNVQPTCALTGDGLLEGLAWLSQNAKLK.. 184
4 -89.100[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  30  10............LKSAPDQEVRILLLGLDNAGKTTLLKQLASED-ISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAKKK 182
5 -89.100[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  30  1MGLSFGKL---FSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIV-TTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSNNIASKA. 181
6 -88.600[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  29  1MGNIFSSMFDKLWG--SNKELRILILGLDGAGKTTILYRLQIGEVV-TTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTASKELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKEEQ. 182
7 -88.200[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  29  1....MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGED-IDTISPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGATLLIFANKQDLPGALSSNAIREALELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSRIF 181
8 -82.400[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  29  1.MFLFDWFYGILASLLWQKEAKILFLGLDNAGKTTLLHMLKDER-LVQHQPTQHPTSEELSIGKIKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYDKERFAESKRELDALLSDEALATVPFLILGNKIDIPYAASEDELRYHLGLTNFTTRPLEVFMCSIVRKMGYGEGFKWLSQYIN.... 193
9 -80.100[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  27  1MFHLVKGL---YNNWNKKEQYSILILGLDNAGKTTFLETLKKEKALEKIQPTVGQNVATIPVDSKQLKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRERLDECSTTLQSVVMDEEIEGVPILMLANKQDRQDRMEVQDIKEVFNKEHISARDSRVLPISALTGEGVKDAIEWMIVRLERNKK 191
10 -52.900[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  19  36VLLLATIWLLSIRLFRRTKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALEFLPIRAASEYLYDILTNASVNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEIDKLRVSRSAISTADIANDFTLGIEGEVFSFSH... 230
11 -38.400[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  17  55............DPFSTEVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLSTNKICREDVSNSFVNFQIWDFPGQIDFFDPYEMIFRGTGALIFVIDSQDDYMEALARLHLTVTRAYKVNTDINFEVFIHKVDGLSDDHKIETQRDIHQRANDDKIHLSFYLTSIYDHSIFEAFSKVVQKLIPQLP 242
12 -35.000[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  22  10....................FRLILIGDSTVGKSSLLKFFTDGKFAELSDPTVGFFARLIEMKDIKLQLWDTAGQERFRSITKSYYRNSVGVLLVYDISNHASFEHIPLWMMEAQRHIEPHRPVFALVGCKLDLINAGGHREVTTEEAQKFAKQHGLHFVETSARSGANVEEAFRMVTQEVYARIR 180
13 -34.800[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  24  13....................FKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDL--VRVCENIPIVLCGNKVDVKERKVKAK-----TITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQ 175
14 -34.700[R] COG2229 Predicted GTPase  ali follow..  19  2..................RENKIIFTGPVGVGKTTAIAAISDEALVQTRNTTVAMDYGAISLDDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNARTNPLKDLEFFLHSF--RGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAKHNL---NVPVFEIDARKEDDVKQLVSAMLFSIDPGLE 177
15 -33.700[U] KOG0081 GTPase Rab27, small G protein superfamily  ali follow..  21  10....................IKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGFREKRVVYRAIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLE---DQRVVKEEEAIALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRME 186
16 -33.400[R] KOG0394 Ras-related GTPase  ali follow..  19  9....................LKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGFLTKEVQFEDFTLQIWDTAGQERFQSLGVAFYRGADCCVLVYDVNSMKSFENLNEEFLIQASPSDPENFPFVLIGNKVDVDDGNSRVVSEKKAKAWCASKGNIPYFETSAKVGTNVEEAFQCIAKDALKSGE 181
17 -33.100[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  18  9....................LKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKSVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFA----RKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPG 174
18 -32.200[TU] KOG0084 GTPase Rab1/YPT1, small G protein superfamily, and related GTP-binding proteins  ali follow..  21  9....................FKLLLIGDSGVGKSCLLLRFADDSYLDSYISTIGVDFKEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVTYDVTDLESFNNVKQWLNEIDRYAS-ENVNKLLVGNKCDLT---SQKVVSTETAKAFADELGIPFLETSAKNATNVEEAFMAMTAAIKTRMA 174
19 -32.100[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  19  13....................FKIVLLGEGCVGKSSLVLRFVENKFSCKHLSTIQFQNKTVNVEDADLHIWDTAGQEKYHALGPIYYRGSNGVLLVFDITDRKSFEKVKNWVLEIKTCLG-NTAEILIVGNKIDLE---EERQVTRQDAEAYAESEGALYMETSAQDNVGISDAFESLTAKMIEHSR 178
20 -32.100[TU] KOG0078 GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins  ali follow..  21  10....................IKLLLIGDSGVGKSCLLLRFSEDSFTPSFITTIGIDFKELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLLYDVTDKKSFDNVRTWFSNVEQHAS-ENVYKILIGNKCDCE---DQRQVSFEQGQALADELGVKFLEASAKTNVNVDEAFFTLAREIKKQKI 175
21 -32.100[R] KOG0079 GTP-binding protein H-ray, small G protein superfamily  ali follow..  21  11....................FKLLIIGDSGVGKSSLLLRFADNTFSENYITTIGVDFKDINGQRVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTNGESFGNVKRWLQEI--ENNCDSVQKVLVGNKCEEN---ERRVVLESDARNYAQSMNISFFETSAKEDKNVEPMFTCITSLVLTAKL 175
22 -32.100[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  22  21....................FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGFLTQTVCLDDVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQAS-PNIVIALSGNKADLA---NKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEP 186
23 -31.900[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  23  10....................FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVGFMEINGEKVKLQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYAS-NKVITVLVGNKIDLA---ERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEAR 175
24 -31.800[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  20  10....................YKLVFLGDQSVGKTSIITRFMYDKFDTTYQATIGFLSKTMYLEDVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDVANRLSFLNTSKWIEEVRNERA-GDVIIVLVGNKTDLV---EKRQVSIEEGDSKGREYGVMFIETSAKAGFNIKPLFRKIAAALPGMES 175
25 -31.400[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  19  9....................FKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLAS-PNIVVILCGNKKDLD---PEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKID 174
26 -31.400[U] KOG0093 GTPase Rab3, small G protein superfamily  ali follow..  22  23....................FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGFKVKTIYRNDIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSW-DNAQVLLVGNKCDME---DERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMS 188
27 -31.300[T] KOG4252 GTP-binding protein  ali follow..  23  10....................IKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGFLERQIQVNDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRGSFEAVSSWREKV--VAEVGDIPTVLVQNKIDLL---DDSCIKNEEAEALAKRLRLRFYRTSVKEDLNVNEVFKYLAEKYLQKLK 174
28 -31.200[R] KOG0395 Ras-related GTPase  ali follow..  18  17.................KNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIE-KVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILETKEAAELPMVICGNKNDHGELCRQVPTTEAELLVS-GDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHE 195
29 -31.000[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  16  12....................FKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGEVSGQKIKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTN-PNTVIILIGNKADLE---AQRDVTYEEAKQFAEENGLLFLEASAKTGENVEDAFLEAAKKIYQNIQ 177
30 -30.700[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  19  11....................FKTVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGFATRNIVLDNIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITKQSSFDNVGRWLKELREHAD-SNIVIMLVGNKTDLL---HLRAVSTEEAQAFAAENNLSFIETSAMDASNVEEAFQTVLTEIFRIVS 176
31 -30.700[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  16  7....................FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGTIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTSWLEDARQHSN-SNMVIMLIGNKSDLE---ARREVKREEGEAFAREHGLVFMETSAKTAANVEEAFIDTAKEIYRKIQ 172
32 -29.500[T] KOG3886 GTP-binding protein  ali follow..  17  38.................AMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRATILDRIHSLQIGNLVLNLWDCGGQDTFMENYDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSDAKIFCLVHKMDLVQEDQRDLIFKERELRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQ 246
33 -27.600[R] KOG1673 Ras GTPases  ali follow..  16  102....................LKISLLGDCQTGKTTFVVKYVGDEN-QSFLEMTGLNLMDVQGVTISFSIWDVGGDERSKDHIPIACKDAVAILFMFDLTSRSTLNSVFGWYSQA--RKWNKTAIPILIGTKFDDFVRLPPNWTIVTQARAYAKVMNASLFFSSATHNINVNKIFKFILARLFNLP. 270
34 -27.200[R] KOG0083 GTPase Rab26/Rab37, small G protein superfamily  ali follow..  21  469....................GKVIMLGDSGVGKTSLLIRFRDGRYVPSFLSTVGIDFRVVDGTRVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKTTYDNIRAWLGEIREYAQ-EDVVIVLIGNKADCSG--SERQVKREDGERLGREHNVPFMETSAKTGLNVELSFTAVARQLKSR.. 634
35 -25.000[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  14  2..................QAIKCVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNNPASFENVRAKWYPEVSH-HCPNTPIILVGTKADLREDRDTIERLRESRLQPVSHTQVKYLECSALTQIGLKQVFDEAIRTGLTPPQ 181
36 -25.000[R] COG1084 Predicted GTPase  ali follow..  16  160.................LDAFTVVIAGFPNVGKSTLLRTLTGAEPEVADYPTKGIQIGHLERKWKRIQVIDTPGNNIELQAMVALENIADVIMFIFDASETCG-YTLESQYSLYLGIRSVFDIPVVTVFNKMDLAENVKY--------LEEYINMVEDPLKVSAFEGRGVSKIIKKLEGLYEKETR 330
37 -21.700[E] COG4917 Ethanolamine utilization protein  ali follow..  16  3.....................RIAFVGSVGAGKTTLFNALQGNYTLARKTQAVEFNDKGD----------DTPGHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLL-------DIGVSKRQIAVISKTDMPDA-DVAATRKLLLETGFEEP---MFELNSHDPQSVQQLVDYLASLTKQEE. 150
38 -21.700[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  16  2.......WMGVGDSSGSPKPIRIVVVGEKGSGKSSLIMAAARNTFHPNIPSLLPYTNSEFFPDRIPATVIDTSSRPEDKGKVVKEVRQADAIVLTFAFDRPETLDRLSKYWLPLFRQLE-VRVPIIVAGYEVDNKEAYNHFSIEQITSALMKQYRE-TSIQWSAQRLDQAKDVLYYAQKAV..... 177
39 -21.200[R] COG3596 Predicted GTPase  ali follow..  10  36.................HYEPVIGIMGKTGAGKSSLCNAL-FAGEVSPVSDVAACTRDRLQIGEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADD--RALATDEHFYRQVIGEA-YRHKMLFVISQSDKAEPTSGGNILSTEQKQNISRKI-PVCAVSVRLQWGLRVMAERMIKCLPREPS 221
40 -20.800[R] KOG2486 Predicted GTPase  ali follow..  18  137.....................EFALVGRSNVGKSSLLNSLVRRKRLALTSKKPG-KTQCINH-NDKWYLVDLPGKQDWNKFTKDYFSTLVSVFLLVDA--SIPVKPIDLEYASWLGQ---NQVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDL--PWIMTSSVTNQGRDEILLHMAQLRNYWLK 317
41 -20.300[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  12  170.....................TVLICGYPNVGKSSFMNKVTRADVDVQPYATKSLFVGHTDYKYLRYQVIDTPG-EMCSITALAHLRAAVLFFLDISGSCGYTIAQQAALFHSI--KSLFMNKPLVIVCNKTDLMPMENISEEDRKLKTAMGASEEQVLLKMSTLTDEGVMSVKNAACERLLDQR. 353
42 -20.100[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  21  337.................KSIADLGLIGLPNAGKSTILNKISNAKPKTTLSPTIG--TVSLGFGQDVFTVADIPGDKGMGLEFLRHIERSNGWVFVLDLSNKNPLNDLQLLIEEVGTLEKVKTKNILIVCNKVDIDAEKSESFAKYLQVEKFSKSQEWDCVPISALREKT................. 499
43 -19.200[T] KOG0099 G protein subunit Galphas, small G protein superfamily  ali follow..  27  38.................RATHRLLLLGAGESGKSTIVKQMRIQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNRLQEALNLFKSIWNNRWLRTISVILFLNKQDL.................................................... 296
44 -18.900[T] KOG0085 G protein subunit Galphaq/Galphay, small G protein superfamily  ali follow..  21  37.................RRELKLLLLGTGESGKSTFIKQMRIQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLEDKILYSHLVDYFDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLN. 352
45 -18.900[DT] KOG0082 G-protein alpha subunit (small G protein superfamily)  ali follow..  20  31.................ARTVKLLLLGAGESGKSTIVKQMKIQDVLHSRVKTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAEDEEVNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDI.................................................... 273
46 -18.500[R] COG0218 Predicted GTPase  ali follow..  17  27.....................EIALAGRSNVGKSSFINTMLNRKNLARTSGKPG-KTQLLNFFNIKMRFVDVPGSKKEREKWGCMIENLRAVVSLVDL--RHDPSADDVQMYEFLKY---YEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL..... 195
47 -17.700[P] COG0370 Fe2+ transport system protein B  ali follow..  13  2..................SQNTYCILGNPNTGKTSLFNALTGSYEYVGNWSGVTVEKKVGTLRSKTGKLIDLPGIYDLNPISRD--EKFDCMLNIVDSSQIERNLNLTVQLLEY-------GAPVVMGLNMIDVAAGLNIQNLAKKLRIP--------ILPVVARSGKGTEDILSTLSEKHVAPAI 166
48 -17.600[S] KOG4273 Uncharacterized conserved protein  ali follow..  12  2.................ESRPGVLVVGSSGVGKRTLLSRLLSVEFEDSSESSSQTEVHNTKYYTADVSVCISHICDEYSLPNLPNSHPLVALVMVFDLSELSTLVALQDWVSHT---DINSFDILLCIGNKVDREYRRRLLKASDPSRDLYSDIDDFGISETEGSSLLGSEDALEWCSEN...... 181
49 -17.100[R] COG1160 Predicted GTPases  ali follow..  15  5.....................VVALVGRPNVGKSTLFNRL-TRTRDALVADFPGLTRDRKHIAGYDFIVIDTGGEEKMAEQSLLAIDEADIVLFLVDA--RAGLTAADIGIANYLRQR--QNKITVVVANKTDGIDADSHCAEFYQLGLGE-------IEQIAASQGRGVTQLMEQVLAPFAEKME 169
50 -16.900[R] COG0536 Predicted GTPase  ali follow..  21  155...................ELKSMLVGFPSAGKSSLISVMSAAKPKIGDYPTLQPNLGVVNVGHETFTMADVPGGKGLGLDFLRHIERTSVLVHVVDTATMDPGRDPISDIEALEAE-DLSQRPRLVVLNKADVPEA---EELAEFLKEDIEKQFGWPVFIISAVARKGLDPLKYKLLEIVQDARK 345
51 -15.800[R] COG1163 Predicted GTPase  ali follow..  16  59.............DVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYETLVTVPGVIRYKGAKIQMLDLPGGRGRGKQVIAVARTCNLLFIILDVNKPHHKQIIEKELEGV--GIRLNKTPPDILIKKKEKGGI................................................. 190
52 -15.700[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  18  58.............DVAKTGDARIGFVGFPSVGKSTLLSNLAGVYSEVAAYETLTTVPGVIRYKGAKIQLLDLPGGKGRGRQVIAVARTCNLILIVLDVLKPGHKKIIENELEGF--GIRLNSKPPNIGFKKKDKGGI................................................. 189
53 -15.100[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  15  39.................QATINIGTIGHVAHGKSTVVKAISKNELERNITIKLGYANAKIFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAI---EIMKLKHILILQNKIDLVKERQAKEQYEQILVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPR 248
54 -14.800[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  13  56.............EVTKYGHGRVALIGFPSVGKSTLLTMLTGTHSEAASYETLTCIPGVIHYNDTKIQLLDLPGGKGRGRQVIAVAKSSDLVLMVLDSKSEGHRQILTKELEAV--GLRLNKTPPQIYFKKKKTGGI................................................. 187
55 -14.400[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali follow..  17  183......................VTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADD------VMKQTVESIQHAKDAQVPIILAVNKCDKAEA-DPEKVKKELLAYDVVCEDYQAVPVSALTGDNLMALAEATV........ 339
56 -14.300[R] COG0486 Predicted GTPase  ali follow..  18  225.................REGMKVVIAGRPNAGKSSLLNALAGREIVTDIAGTTRDVLREIHIDGMPLHIIDTAGLREATDE-WSEIEQADRILLMLDSTEA--DNQDLEKVRSEFLTKLPSNIPVTIVRNKADLSGENEGIVEQNGYTVITL----------SAKTQQGIALLREHLKQSMGYQ.. 390
57 -14.000[R] COG1159 GTPase  ali follow..  17  11......................IAIVGRPNVGKSTLLNKLLGQKITSRKAQTTRHRIVGITEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTRWTPDDE------MVLNKLRDGKAPVILAVNKVDN--VQEKVDLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPE... 175
58 -13.900[R] KOG0410 Predicted GTP binding protein  ali follow..  18  283....IGVLKKELESVRKHRKQYVSLVGYTNAGKSTLLNQLTGANVLNRLFATLDPTTRRVQMNGKEFLLTDTVG-AAFRATLEE-IAESSLLVHVVDISHPL-AEQQIEAVEKVMSELDVSSIPKLVVWNKVDRVDDPQKVKLEAEETGDTI--------CISALTGEGLDDFCNAVHEKLKDSMV 477
59 -13.800[J] COG4108 Peptide chain release factor RF-3  ali follow..  15  13.................SKRRTFAIISHPDAGKTTITEKVSNQHAKSDWMESVTTSVMQFPYGDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAK------VEDRTRKLMEVTRLRDTPIVTFMNKLDREIR-LMDEVENELKIACS.................................. 169
60 -13.600[R] COG2262 GTPases  ali follow..  18  200......................VSLVGYTNAGKSTLFNRITEARVYDQLFATLDPTLRRIDVDVGETVLADTVG-AAFKATLQE-TRQATLLLHVIDAADVR-VQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPR-------IDRDEENKPIRVWLSAQTGAGIPQLFQALTERLSGEVA 366
61 -13.200[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  16  1..............MKNQSEINIGLVGHVDHGKTTLTKALSSEETKRGISIRLGYADITFTELLRKVSFVDAPGHETLMATMLSGAALMDGAILVIAANEPCPQPQTKEHLMAL---DVIGVKDVIVVQNKIDIVSKERALESYREIKVKGTCAEDAPIIPVSAQQGANIDILIETIEERIKTPKR 202
62 -13.100[J] KOG1191 Mitochondrial GTPase  ali follow..  14  351.................QSGLQIAIVGRPNVGKSSLLNAWSKSEIVTEVAGTTRDVVEAVTVRGVPITLLDTAGIRETNDI-ETAAKVADVIIMAVSAVEGWTEEDTEVSFYDLFGGLLYLKQPMILVMNKIDCAPPGSCDQLEDQRKKEEVFHKSVFT---SAVTGQGIEELEDAILEILGLDR. 537
63 -12.900[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  12  2.................KRPLIIGVGGPVGAGKTMLIERLTKGYSMAAITNDIYTKEDADKHPDLQLLFLESGGDNLSATF---SPDLVDFSIYIIDVAQGEKIPRKGGQGMIKSD---------LFIINKVDLAPYVGANVEVMKADTLKSRGNK-DFFVTNLKTDEGLKSVADWIEKRLQLALL 204
64 -12.900[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali follow..  22  448......................VTIMGHVDHGKTTLLDRFRESRVTEGEA-TQHIGAYQIKANGKKITFLDTPGHEAFTSMRARGASVTDITILVVAADD------VMPQTIEAINHSKAAGVPIIVAINKIDKPGA-NPQRVTQELTEHGVFPVAWEFVEISAKFNQNLDELLDTVL........ 605
65 -12.400[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  20  44.....................NFGIVAHVDHGKSTLADRLPGQKQMLDKLQTVKAQTAALRHRGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQ------VQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNLFEFNPEE--CLHISAKSGLNVDKVLEAIIDRV..... 211
66 -12.000[M] COG0481 Membrane GTPase LepA  ali follow..  16  6.....................NFSIIAHIDHGKSTLSDRLERERGITIKAQSVTLNYKAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQ------VEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDIVGIDAME--AVRCSAKTGVGIEDVLEEIVHKI..... 180
67 -12.000[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  20  8.................KPHLNLITIGHVDHGKSTLVGRLEHGEIPAHIIETIDLAHRKFETDKYYFTLIDAPGHRDFVKNMITGTSQADAAILVISAREGEGVMEQTREHAFLARTLGVPQ--MVVAINKMDATSPPYSEKRYNEVKLRSIGFKDISFVPISGYKGDNVSPNMPW.......... 206
68 -11.900[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  16  5.................KVHINIVVIGHVDSGKSTTTGHLKCGGIDKRTIETIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTEAGISKNGQTREHALLAQTLGVKQLIVACNKMDSTEP--TNEVSGFIKKIGYNPKAVPFVPISGFNGDNMLE.............. 203
69 -11.500[J] KOG0468 U5 snRNP-specific protein  ali follow..  19  133.....................NVALVGHLHHGKTTFVDCLEQERGCSIKATPVTLVLQDVKQKSYLLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDA-----AEGVMLNTERLLKHAVQERQAITVCINKIDRLILLPPQDAYFKLK...................................... 281
70 -11.300[J] KOG0458 Elongation factor 1 alpha  ali follow..  12  165.................LPHLSFVVLGHVDAGKSTLMGRLDLNIVNQSQLRTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVD---KSKLLPYLVDIGFFEDNINWVPISGFSGEGVYK.............. 361
71 -11.000[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  18  51.................KPHVNIGTIGHVDHGKTTLTAAIKAPEEKARGI-TISSAHVEYETANRHYAHVDCPGHADYIKNMITGAATMDGAIIVVSATD---MPQTREHLLLA---RQVGVKQIVVYINKVDMVEELVEMEMRELLSEYGFDGDNTPIVSGSALCA................... 218
72 -10.800[J] COG0480 Translation elongation factors (GTPases)  ali follow..  17  12.....................NIGIAAHIDAGKTTTTERIHEGTAVTDWMDTITAAAISTSWKDYQINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVG------VQPQSETVWRQADRYKVPRIAFINKMDRTGA-VHEQMRDRLRANAI.................................. 160
73 -10.800[J] KOG0459 Polypeptide release factor 3  ali follow..  17  99.................KRHLNVVFIGHVDAGKSTIGGQILSGQVDDRQIQTVEVGRAHFETESTRFTILDAPGHKSYVPNMISGASQADIGVLVISARKETGYERGGQTREHVQLAKTLGVSKLIVVVNKMDDPTVNWSKERYDEIASGYNTKKDVVFLPISGLMGKNMDQ.............. 298
74 -10.800[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  19  3.................ENLRNIAIIAHVDHGKTTLVDKLRKEAESERVMDTILAKNTAIKWNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQD------PMPQTRFVTQKAFKAGLRPIVVVNKIDRPGARPDWVIDQIFDLFDNLGATDEQLDFPIVYASALN............... 169
75 -10.500[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  18  3......................IVTSGHVDHGKTALLKAL-TGTSTAHLPETIDLGYAYLPLENKVLGFIDVPGHEKFLSNMLAGLGGVHYAMLIV-AADEGVAVQTKEHLAIL---RQLQFHEIIVVITKADRTNSAQIESLIQTIKQDYSFLRNANYFVTSAETGQGISELRHYLANLAELADT 167

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Database searching by flexible protein structure alignment. Protein Sci. 2004 Jul;13(7):1841-50.